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Items: 1 to 50 of 254

1.

Multimodal assessments of Zika virus immune pathophysiological responses in marmosets.

Lum FM, Zhang W, Lim KC, Malleret B, Teo TH, Koh JJ, Lee KJ, Chua TK, Kam YW, Yee WX, Huen I, Tan JJL, Amrun SN, Prakash Kn B, Cozzone PJ, Renia L, Lee PTH, Ng LFP.

Sci Rep. 2018 Nov 20;8(1):17125. doi: 10.1038/s41598-018-35481-6.

PMID:
30459473
2.

Plasmodium co-infection protects against chikungunya virus-induced pathologies.

Teo TH, Lum FM, Ghaffar K, Chan YH, Amrun SN, Tan JJL, Lee CYP, Chua TK, Carissimo G, Lee WWL, Claser C, Rajarethinam R, Rénia L, Ng LFP.

Nat Commun. 2018 Sep 25;9(1):3905. doi: 10.1038/s41467-018-06227-9.

3.

A Plasmodium Cross-Stage Antigen Contributes to the Development of Experimental Cerebral Malaria.

Fernandes P, Howland SW, Heiss K, Hoffmann A, Hernández-Castañeda MA, Obrová K, Frank R, Wiedemann P, Bendzus M, Rénia L, Mueller AK.

Front Immunol. 2018 Aug 14;9:1875. doi: 10.3389/fimmu.2018.01875. eCollection 2018.

4.

A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection.

Zanghì G, Vembar SS, Baumgarten S, Ding S, Guizetti J, Bryant JM, Mattei D, Jensen ATR, Rénia L, Goh YS, Sauerwein R, Hermsen CC, Franetich JF, Bordessoulles M, Silvie O, Soulard V, Scatton O, Chen P, Mecheri S, Mazier D, Scherf A.

Cell Rep. 2018 Mar 13;22(11):2951-2963. doi: 10.1016/j.celrep.2018.02.075.

5.

Doxycycline inhibits experimental cerebral malaria by reducing inflammatory immune reactions and tissue-degrading mediators.

Schmidt KE, Kuepper JM, Schumak B, Alferink J, Hofmann A, Howland SW, Rénia L, Limmer A, Specht S, Hoerauf A.

PLoS One. 2018 Feb 13;13(2):e0192717. doi: 10.1371/journal.pone.0192717. eCollection 2018.

6.

Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity.

Lum FM, Couderc T, Chia BS, Ong RY, Her Z, Chow A, Leo YS, Kam YW, Rénia L, Lecuit M, Ng LFP.

Sci Rep. 2018 Jan 30;8(1):1860. doi: 10.1038/s41598-018-20305-4.

7.

Prime-boost vaccination with recombinant protein and adenovirus-vector expressing Plasmodium vivax circumsporozoite protein (CSP) partially protects mice against Pb/Pv sporozoite challenge.

de Camargo TM, de Freitas EO, Gimenez AM, Lima LC, de Almeida Caramico K, Françoso KS, Bruna-Romero O, Andolina C, Nosten F, Rénia L, Ertl HCJ, Nussenzweig RS, Nussenzweig V, Rodrigues MM, Reyes-Sandoval A, Soares IS.

Sci Rep. 2018 Jan 18;8(1):1118. doi: 10.1038/s41598-017-19063-6.

8.

In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate.

Cravo P, Machado RB, Leite JA, Leda T, Suwanarusk R, Bittencourt N, Albrecht L, Judice C, Lopes SCP, Lacerda MVG, Ferreira MU, Soares IS, Goh YS, Bargieri DY, Nosten F, Russell B, Rénia L, Costa FTM.

Malar J. 2018 Jan 10;17(1):20. doi: 10.1186/s12936-017-2144-x.

9.

Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax.

Gruszczyk J, Kanjee U, Chan LJ, Menant S, Malleret B, Lim NTY, Schmidt CQ, Mok YF, Lin KM, Pearson RD, Rangel G, Smith BJ, Call MJ, Weekes MP, Griffin MDW, Murphy JM, Abraham J, Sriprawat K, Menezes MJ, Ferreira MU, Russell B, Renia L, Duraisingh MT, Tham WH.

Science. 2018 Jan 5;359(6371):48-55. doi: 10.1126/science.aan1078.

10.

Interferon regulatory factor 1 is essential for pathogenic CD8+ T cell migration and retention in the brain during experimental cerebral malaria.

Gun SY, Claser C, Teo TH, Howland SW, Poh CM, Chye RRY, Ng LFP, Rénia L.

Cell Microbiol. 2018 May;20(5):e12819. doi: 10.1111/cmi.12819. Epub 2018 Jan 18.

PMID:
29281764
11.

In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial.

Basilico N, Parapini S, Sparatore A, Romeo S, Misiano P, Vivas L, Yardley V, Croft SL, Habluetzel A, Lucantoni L, Renia L, Russell B, Suwanarusk R, Nosten F, Dondio G, Bigogno C, Jabes D, Taramelli D.

Molecules. 2017 Dec 1;22(12). pii: E2102. doi: 10.3390/molecules22122102.

12.

Singapore's Anopheles sinensis Form A is susceptible to Plasmodium vivax isolates from the western Thailand-Myanmar border.

Pang SC, Andolina C, Malleret B, Christensen PR, Lam-Phua SG, Razak MABA, Chong CS, Li D, Chu CS, Russell B, Rénia L, Ng LC, Nosten F.

Malar J. 2017 Nov 16;16(1):465. doi: 10.1186/s12936-017-2114-3.

13.

Co-infection with Chikungunya virus alters trafficking of pathogenic CD8+ T cells into the brain and prevents Plasmodium-induced neuropathology.

Teo TH, Howland SW, Claser C, Gun SY, Poh CM, Lee WW, Lum FM, Ng LF, Rénia L.

EMBO Mol Med. 2018 Jan;10(1):121-138. doi: 10.15252/emmm.201707885.

14.

Dual modal ultra-bright nanodots with aggregation-induced emission and gadolinium-chelation for vascular integrity and leakage detection.

Feng G, Li JLY, Claser C, Balachander A, Tan Y, Goh CC, Kwok IWH, Rénia L, Tang BZ, Ng LG, Liu B.

Biomaterials. 2018 Jan;152:77-85. doi: 10.1016/j.biomaterials.2017.10.031. Epub 2017 Oct 20.

PMID:
29111495
15.

Constructing cell lineages from single-cell transcriptomes.

Chen J, Rénia L, Ginhoux F.

Mol Aspects Med. 2018 Feb;59:95-113. doi: 10.1016/j.mam.2017.10.004. Epub 2017 Nov 26. Review.

PMID:
29107741
16.

Quantitative mass spectrometry of human reticulocytes reveal proteome-wide modifications during maturation.

Chu TTT, Sinha A, Malleret B, Suwanarusk R, Park JE, Naidu R, Das R, Dutta B, Ong ST, Verma NK, Chan JK, Nosten F, Rénia L, Sze SK, Russell B, Chandramohanadas R.

Br J Haematol. 2018 Jan;180(1):118-133. doi: 10.1111/bjh.14976. Epub 2017 Nov 2.

PMID:
29094334
17.

Vaccine Containing the Three Allelic Variants of the Plasmodium vivax Circumsporozoite Antigen Induces Protection in Mice after Challenge with a Transgenic Rodent Malaria Parasite.

Gimenez AM, Lima LC, Françoso KS, Denapoli PMA, Panatieri R, Bargieri DY, Thiberge JM, Andolina C, Nosten F, Renia L, Nussenzweig RS, Nussenzweig V, Amino R, Rodrigues MM, Soares IS.

Front Immunol. 2017 Oct 11;8:1275. doi: 10.3389/fimmu.2017.01275. eCollection 2017.

18.

Safety and effectiveness of mass drug administration to accelerate elimination of artemisinin-resistant falciparum malaria: A pilot trial in four villages of Eastern Myanmar.

Landier J, Kajeechiwa L, Thwin MM, Parker DM, Chaumeau V, Wiladphaingern J, Imwong M, Miotto O, Patumrat K, Duanguppama J, Cerqueira D, Malleret B, Rénia L, Nosten S, von Seidlein L, Ling C, Proux S, Corbel V, Simpson JA, Dondorp AM, White NJ, Nosten FH.

Wellcome Open Res. 2017 Sep 6;2:81. doi: 10.12688/wellcomeopenres.12240.1. eCollection 2017.

19.

Deep Sequencing of RNA from Blood and Oral Swab Samples Reveals the Presence of Nucleic Acid from a Number of Pathogens in Patients with Acute Ebola Virus Disease and Is Consistent with Bacterial Translocation across the Gut.

Carroll MW, Haldenby S, Rickett NY, Pályi B, Garcia-Dorival I, Liu X, Barker G, Bore JA, Koundouno FR, Williamson ED, Laws TR, Kerber R, Sissoko D, Magyar N, Di Caro A, Biava M, Fletcher TE, Sprecher A, Ng LFP, Rénia L, Magassouba N, Günther S, Wölfel R, Stoecker K, Matthews DA, Hiscox JA.

mSphere. 2017 Aug 23;2(4). pii: e00325-17. doi: 10.1128/mSphereDirect.00325-17. eCollection 2017 Jul-Aug.

20.

The G6PD flow-cytometric assay is a reliable tool for diagnosis of G6PD deficiency in women and anaemic subjects.

Bancone G, Kalnoky M, Chu CS, Chowwiwat N, Kahn M, Malleret B, Wilaisrisak P, Rénia L, Domingo GJ, Nosten F.

Sci Rep. 2017 Aug 29;7(1):9822. doi: 10.1038/s41598-017-10045-2.

21.

Specific Biomarkers Associated With Neurological Complications and Congenital Central Nervous System Abnormalities From Zika Virus-Infected Patients in Brazil.

Kam YW, Leite JA, Lum FM, Tan JJL, Lee B, Judice CC, Teixeira DAT, Andreata-Santos R, Vinolo MA, Angerami R, Resende MR, Freitas ARR, Amaral E, Junior RP, Costa ML, Guida JP, Arns CW, Ferreira LCS, Rénia L, Proença-Modena JL, Ng LFP, Costa FTM; Zika-Unicamp Network.

J Infect Dis. 2017 Jul 15;216(2):172-181. doi: 10.1093/infdis/jix261.

22.

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

Takata K, Kozaki T, Lee CZW, Thion MS, Otsuka M, Lim S, Utami KH, Fidan K, Park DS, Malleret B, Chakarov S, See P, Low D, Low G, Garcia-Miralles M, Zeng R, Zhang J, Goh CC, Gul A, Hubert S, Lee B, Chen J, Low I, Shadan NB, Lum J, Wei TS, Mok E, Kawanishi S, Kitamura Y, Larbi A, Poidinger M, Renia L, Ng LG, Wolf Y, Jung S, Önder T, Newell E, Huber T, Ashihara E, Garel S, Pouladi MA, Ginhoux F.

Immunity. 2017 Jul 18;47(1):183-198.e6. doi: 10.1016/j.immuni.2017.06.017.

23.

Strict tropism for CD71+/CD234+ human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi.

Kosaisavee V, Suwanarusk R, Chua ACY, Kyle DE, Malleret B, Zhang R, Imwong M, Imerbsin R, Ubalee R, Sámano-Sánchez H, Yeung BKS, Ong JJY, Lombardini E, Nosten F, Tan KSW, Bifani P, Snounou G, Rénia L, Russell B.

Blood. 2017 Sep 14;130(11):1357-1363. doi: 10.1182/blood-2017-02-764787. Epub 2017 Jul 11.

24.

Adaptive immunity is essential in preventing recrudescence of Plasmodium yoelii malaria parasites after artesunate treatment.

Claser C, Chang ZW, Russell B, Rénia L.

Cell Microbiol. 2017 Nov;19(11). doi: 10.1111/cmi.12763. Epub 2017 Jul 20.

PMID:
28664674
25.

Singapore Malaria Network Meeting (SingMalNet) 2016.

Preiser P, Renia L, Bozdech Z, Tan K, Russell B, Cooke BM.

Int J Parasitol. 2017 Jun;47(7):369-370. doi: 10.1016/j.ijpara.2017.05.001. No abstract available.

PMID:
28622798
26.

Asian G6PD-Mahidol Reticulocytes Sustain Normal Plasmodium Vivax Development.

Bancone G, Malleret B, Suwanarusk R, Chowwiwat N, Chu CS, McGready R, Rénia L, Nosten F, Russell B.

J Infect Dis. 2017 Jul 15;216(2):263-266. doi: 10.1093/infdis/jix278.

27.

Mapping the human DC lineage through the integration of high-dimensional techniques.

See P, Dutertre CA, Chen J, Günther P, McGovern N, Irac SE, Gunawan M, Beyer M, Händler K, Duan K, Sumatoh HRB, Ruffin N, Jouve M, Gea-Mallorquí E, Hennekam RCM, Lim T, Yip CC, Wen M, Malleret B, Low I, Shadan NB, Fen CFS, Tay A, Lum J, Zolezzi F, Larbi A, Poidinger M, Chan JKY, Chen Q, Rénia L, Haniffa M, Benaroch P, Schlitzer A, Schultze JL, Newell EW, Ginhoux F.

Science. 2017 Jun 9;356(6342). pii: eaag3009. doi: 10.1126/science.aag3009. Epub 2017 May 4.

PMID:
28473638
28.

Four human Plasmodium species quantification using droplet digital PCR.

Srisutham S, Saralamba N, Malleret B, Rénia L, Dondorp AM, Imwong M.

PLoS One. 2017 Apr 19;12(4):e0175771. doi: 10.1371/journal.pone.0175771. eCollection 2017.

29.

Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections.

Kam YW, Lee CY, Teo TH, Howland SW, Amrun SN, Lum FM, See P, Kng NQ, Huber RG, Xu MH, Tan HL, Choo A, Maurer-Stroh S, Ginhoux F, Fink K, Wang CI, Ng LFP, Rénia L.

JCI Insight. 2017 Apr 20;2(8). pii: 92428. doi: 10.1172/jci.insight.92428. [Epub ahead of print]

30.

The unhealthy attraction of Plasmodium vivax to reticulocytes expressing transferrin receptor 1 (CD71).

Malleret B, Rénia L, Russell B.

Int J Parasitol. 2017 Jun;47(7):379-383. doi: 10.1016/j.ijpara.2017.03.001. Epub 2017 Apr 13. Review.

PMID:
28414070
31.

Host Resistance to Plasmodium-Induced Acute Immune Pathology Is Regulated by Interleukin-10 Receptor Signaling.

Claser C, De Souza JB, Thorburn SG, Grau GE, Riley EM, Rénia L, Hafalla JCR.

Infect Immun. 2017 May 23;85(6). pii: e00941-16. doi: 10.1128/IAI.00941-16. Print 2017 Jun.

32.

Zika Virus Infects Human Fetal Brain Microglia and Induces Inflammation.

Lum FM, Low DK, Fan Y, Tan JJ, Lee B, Chan JK, Rénia L, Ginhoux F, Ng LF.

Clin Infect Dis. 2017 Apr 1;64(7):914-920. doi: 10.1093/cid/ciw878.

PMID:
28362944
33.

Generation, characterization and immunogenicity of a novel chimeric recombinant protein based on Plasmodium vivax AMA-1 and MSP119.

Rocha MV, Françoso KS, Lima LC, Camargo TM, Machado RLD, Costa FTM, Rénia L, Nosten F, Russell B, Rodrigues MM, Soares IS.

Vaccine. 2017 Apr 25;35(18):2463-2472. doi: 10.1016/j.vaccine.2017.03.023. Epub 2017 Mar 22.

PMID:
28341111
34.

Fingolimod treatment abrogates chikungunya virus-induced arthralgia.

Teo TH, Chan YH, Lee WW, Lum FM, Amrun SN, Her Z, Rajarethinam R, Merits A, Rötzschke O, Rénia L, Ng LF.

Sci Transl Med. 2017 Feb 1;9(375). pii: eaal1333. doi: 10.1126/scitranslmed.aal1333.

PMID:
28148838
35.

Corrigendum to "Unambiguous determination of Plasmodium vivax reticulocyte invasion by flow cytometry" [Int. J. Parasitol. 46 (2016) 31-39].

Cho JS, Russell B, Kosaisavee V, Zhang R, Colin Y, Bertrand O, Chandramohanadas R, Chu CS, Nosten F, Renia L, Malleret B.

Int J Parasitol. 2017 Mar;47(4):237. doi: 10.1016/j.ijpara.2017.01.001. Epub 2017 Jan 13. No abstract available.

PMID:
28089659
36.

Severity of Plasma Leakage Is Associated With High Levels of Interferon γ-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.

Her Z, Kam YW, Gan VC, Lee B, Thein TL, Tan JJ; SIgN Immunomonitoring Platform, Lee LK, Fink K, Lye DC, Rénia L, Leo YS, Ng LF.

J Infect Dis. 2017 Jan 1;215(1):42-51. doi: 10.1093/infdis/jiw494. Epub 2016 Oct 17.

PMID:
28077582
37.

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice.

Lee WW, Teo TH, Lum FM, Andiappan AK, Amrun SN, Rénia L, Rötzschke O, Ng LF.

Sci Rep. 2016 Nov 25;6:37603. doi: 10.1038/srep37603.

38.

Malaria Parasites: The Great Escape.

Rénia L, Goh YS.

Front Immunol. 2016 Nov 7;7:463. eCollection 2016. Review.

39.

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.

Chong SZ, Evrard M, Devi S, Chen J, Lim JY, See P, Zhang Y, Adrover JM, Lee B, Tan L, Li JL, Liong KH, Phua C, Balachander A, Boey A, Liebl D, Tan SM, Chan JK, Balabanian K, Harris JE, Bianchini M, Weber C, Duchene J, Lum J, Poidinger M, Chen Q, Rénia L, Wang CI, Larbi A, Randolph GJ, Weninger W, Looney MR, Krummel MF, Biswas SK, Ginhoux F, Hidalgo A, Bachelerie F, Ng LG.

J Exp Med. 2016 Oct 17;213(11):2293-2314. Epub 2016 Oct 10.

40.

UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes.

Lim MY, LaMonte G, Lee MC, Reimer C, Tan BH, Corey V, Tjahjadi BF, Chua A, Nachon M, Wintjens R, Gedeck P, Malleret B, Renia L, Bonamy GM, Ho PC, Yeung BK, Chow ED, Lim L, Fidock DA, Diagana TT, Winzeler EA, Bifani P.

Nat Microbiol. 2016 Sep 19:16166. doi: 10.1038/nmicrobiol.2016.166. [Epub ahead of print]

41.

Ex Vivo Maturation Assay for Testing Antimalarial Sensitivity of Rodent Malaria Parasites.

Chang ZW, Malleret B, Russell B, Rénia L, Claser C.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6859-6866. doi: 10.1128/AAC.01292-16. Print 2016 Nov.

42.

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity.

Karunarathne DS, Horne-Debets JM, Huang JX, Faleiro R, Leow CY, Amante F, Watkins TS, Miles JJ, Dwyer PJ, Stacey KJ, Yarski M, Poh CM, Lee JS, Cooper MA, Rénia L, Richard D, McCarthy JS, Sharpe AH, Wykes MN.

Immunity. 2016 Aug 16;45(2):333-45. doi: 10.1016/j.immuni.2016.07.017.

43.

Rheopathologic Consequence of Plasmodium vivax Rosette Formation.

Zhang R, Lee WC, Lau YL, Albrecht L, Lopes SC, Costa FT, Suwanarusk R, Nosten F, Cooke BM, Rénia L, Russell B.

PLoS Negl Trop Dis. 2016 Aug 10;10(8):e0004912. doi: 10.1371/journal.pntd.0004912. eCollection 2016 Aug.

44.

Tissue-Resident CD169(+) Macrophages Form a Crucial Front Line against Plasmodium Infection.

Gupta P, Lai SM, Sheng J, Tetlak P, Balachander A, Claser C, Renia L, Karjalainen K, Ruedl C.

Cell Rep. 2016 Aug 9;16(6):1749-1761. doi: 10.1016/j.celrep.2016.07.010. Epub 2016 Jul 28.

45.

Neutralizing Antibodies against Plasmodium falciparum Associated with Successful Cure after Drug Therapy.

Goh YS, Peng K, Chia WN, Siau A, Chotivanich K, Gruner AC, Preiser P, Mayxay M, Pukrittayakamee S, Sriprawat K, Nosten F, White NJ, Renia L.

PLoS One. 2016 Jul 18;11(7):e0159347. doi: 10.1371/journal.pone.0159347. eCollection 2016.

46.

Mice lacking Programmed cell death-1 show a role for CD8(+) T cells in long-term immunity against blood-stage malaria.

Horne-Debets JM, Karunarathne DS, Faleiro RJ, Poh CM, Renia L, Wykes MN.

Sci Rep. 2016 May 24;6:26210. doi: 10.1038/srep26210.

47.

Breadth of humoral response and antigenic targets of sporozoite-inhibitory antibodies associated with sterile protection induced by controlled human malaria infection.

Peng K, Goh YS, Siau A, Franetich JF, Chia WN, Ong AS, Malleret B, Wu YY, Snounou G, Hermsen CC, Adams JH, Mazier D, Preiser PR, Sauerwein RW, Grüner AC, Rénia L.

Cell Microbiol. 2016 Dec;18(12):1739-1750. doi: 10.1111/cmi.12608. Epub 2016 May 27.

48.

Reply to "Flow Cytometry for Antimalarial Drug Testing: More than Meets the Eye".

Russell B, Rénia L, Malleret B.

J Clin Microbiol. 2016 Mar;54(3):818-9. doi: 10.1128/JCM.03158-15. No abstract available.

49.

Neutrophils Self-Regulate Immune Complex-Mediated Cutaneous Inflammation through CXCL2.

Li JL, Lim CH, Tay FW, Goh CC, Devi S, Malleret B, Lee B, Bakocevic N, Chong SZ, Evrard M, Tanizaki H, Lim HY, Russell B, Renia L, Zolezzi F, Poidinger M, Angeli V, St John AL, Harris JE, Tey HL, Tan SM, Kabashima K, Weninger W, Larbi A, Ng LG.

J Invest Dermatol. 2016 Feb;136(2):416-24. doi: 10.1038/JID.2015.410.

50.

Measuring antigen presentation in mouse brain endothelial cells ex vivo and in vitro.

Howland SW, Gun SY, Claser C, Poh CM, Rénia L.

Nat Protoc. 2015 Dec;10(12):2016-26. doi: 10.1038/nprot.2015.129. Epub 2015 Nov 12.

PMID:
26562622

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