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Items: 19


The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair.

Sparks JL, Chistol G, Gao AO, Räschle M, Larsen NB, Mann M, Duxin JP, Walter JC.

Cell. 2019 Jan 10;176(1-2):167-181.e21. doi: 10.1016/j.cell.2018.10.053. Epub 2018 Dec 27.


Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts.

Larsen NB, Gao AO, Sparks JL, Gallina I, Wu RA, Mann M, Räschle M, Walter JC, Duxin JP.

Mol Cell. 2019 Feb 7;73(3):574-588.e7. doi: 10.1016/j.molcel.2018.11.024. Epub 2018 Dec 27.


CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination.

Dewar JM, Low E, Mann M, Räschle M, Walter JC.

Genes Dev. 2017 Feb 1;31(3):275-290. doi: 10.1101/gad.291799.116. Epub 2017 Feb 24.


Proteomics reveals a new DNA repair factor involved in DNA damage signaling.

Räschle M.

Mol Cell Oncol. 2016 Nov 29;4(1):e1263713. doi: 10.1080/23723556.2016.1263713. eCollection 2017.


SCAI promotes DNA double-strand break repair in distinct chromosomal contexts.

Hansen RK, Mund A, Poulsen SL, Sandoval M, Klement K, Tsouroula K, Tollenaere MA, Räschle M, Soria R, Offermanns S, Worzfeld T, Grosse R, Brandt DT, Rozell B, Mann M, Cole F, Soutoglou E, Goodarzi AA, Daniel JA, Mailand N, Bekker-Jensen S.

Nat Cell Biol. 2016 Dec;18(12):1357-1366. doi: 10.1038/ncb3436. Epub 2016 Nov 7.


Activation of the ATR kinase by the RPA-binding protein ETAA1.

Haahr P, Hoffmann S, Tollenaere MA, Ho T, Toledo LI, Mann M, Bekker-Jensen S, Räschle M, Mailand N.

Nat Cell Biol. 2016 Nov;18(11):1196-1207. doi: 10.1038/ncb3422. Epub 2016 Oct 10.


Homology-driven assembly of NOn-redundant protEin sequence sets (NOmESS) for mass spectrometry.

Temu T, Mann M, Räschle M, Cox J.

Bioinformatics. 2016 May 1;32(9):1417-9. doi: 10.1093/bioinformatics/btv756. Epub 2016 Jan 6.


TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.

Hoffmann S, Smedegaard S, Nakamura K, Mortuza GB, Räschle M, Ibañez de Opakua A, Oka Y, Feng Y, Blanco FJ, Mann M, Montoya G, Groth A, Bekker-Jensen S, Mailand N.

J Cell Biol. 2016 Jan 4;212(1):63-75. doi: 10.1083/jcb.201506071. Epub 2015 Dec 28.


DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links.

Räschle M, Smeenk G, Hansen RK, Temu T, Oka Y, Hein MY, Nagaraj N, Long DT, Walter JC, Hofmann K, Storchova Z, Cox J, Bekker-Jensen S, Mailand N, Mann M.

Science. 2015 May 1;348(6234):1253671. doi: 10.1126/science.1253671. Epub 2015 Apr 30.


XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4.

Klein Douwel D, Boonen RA, Long DT, Szypowska AA, Räschle M, Walter JC, Knipscheer P.

Mol Cell. 2014 May 8;54(3):460-71. doi: 10.1016/j.molcel.2014.03.015. Epub 2014 Apr 10.


Replication-coupled DNA interstrand cross-link repair in Xenopus egg extracts.

Knipscheer P, Räschle M, Schärer OD, Walter JC.

Methods Mol Biol. 2012;920:221-43. doi: 10.1007/978-1-61779-998-3_16.


Mechanism of RAD51-dependent DNA interstrand cross-link repair.

Long DT, Räschle M, Joukov V, Walter JC.

Science. 2011 Jul 1;333(6038):84-7. doi: 10.1126/science.1204258.


The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.

Knipscheer P, Räschle M, Smogorzewska A, Enoiu M, Ho TV, Schärer OD, Elledge SJ, Walter JC.

Science. 2009 Dec 18;326(5960):1698-701. doi: 10.1126/science.1182372. Epub 2009 Nov 12.


Mechanism of replication-coupled DNA interstrand crosslink repair.

Räschle M, Knipscheer P, Enoiu M, Angelov T, Sun J, Griffith JD, Ellenberger TE, Schärer OD, Walter JC.

Cell. 2008 Sep 19;134(6):969-80. doi: 10.1016/j.cell.2008.08.030. Erratum in: Cell.2009 May 29;137(5):972. Knipsheer, Puck [corrected to Knipscheer, Puck].


Multiple interactions with the Rad51 recombinase govern the homologous recombination function of Rad54.

Raschle M, Van Komen S, Chi P, Ellenberger T, Sung P.

J Biol Chem. 2004 Dec 10;279(50):51973-80. Epub 2004 Sep 30.


Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer.

Nyström-Lahti M, Perrera C, Räschle M, Panyushkina-Seiler E, Marra G, Curci A, Quaresima B, Costanzo F, D'Urso M, Venuta S, Jiricny J.

Genes Chromosomes Cancer. 2002 Feb;33(2):160-7.


Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.

Räschle M, Marra G, Nyström-Lahti M, Schär P, Jiricny J.

J Biol Chem. 1999 Nov 5;274(45):32368-75.

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