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Items: 1 to 50 of 111

1.

Single-Cell Kinetics of siRNA-Mediated mRNA Degradation.

Krzysztoń R, Woschée D, Reiser A, Schwake G, Strey HH, Rädler JO.

Nanomedicine. 2019 Aug 7:102077. doi: 10.1016/j.nano.2019.102077. [Epub ahead of print]

PMID:
31400572
2.

Erratum: Publisher Correction: Multi-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection.

Fröhlich F, Reiser A, Fink L, Woschée D, Ligon T, Theis FJ, Rädler JO, Hasenauer J.

NPJ Syst Biol Appl. 2019 Mar 7;5:11. doi: 10.1038/s41540-019-0083-6. eCollection 2019.

3.

A high-throughput microscopy method for single-cell analysis of event-time correlations in nanoparticle-induced cell death.

Murschhauser A, Röttgermann PJF, Woschée D, Ober MF, Yan Y, Dawson KA, Rädler JO.

Commun Biol. 2019 Jan 24;2:35. doi: 10.1038/s42003-019-0282-0. eCollection 2019.

4.

Age related changes in cell stiffness of tendon stem/progenitor cells and a rejuvenating effect of ROCK-inhibition.

Kiderlen S, Polzer C, Rädler JO, Docheva D, Clausen-Schaumann H, Sudhop S.

Biochem Biophys Res Commun. 2019 Feb 12;509(3):839-844. doi: 10.1016/j.bbrc.2019.01.027. Epub 2019 Jan 11.

5.

A single-cell micro-trench platform for automatic monitoring of cell division and apoptosis after chemotherapeutic drug administration.

Chatzopoulou EI, Raharja-Liu P, Murschhauser A, Sekhavati F, Buggenthin F, Vollmar AM, Marr C, Rädler JO.

Sci Rep. 2018 Dec 21;8(1):18042. doi: 10.1038/s41598-018-36508-8.

6.

Multi-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection.

Fröhlich F, Reiser A, Fink L, Woschée D, Ligon T, Theis FJ, Rädler JO, Hasenauer J.

NPJ Syst Biol Appl. 2018 Dec 10;5:1. doi: 10.1038/s41540-018-0079-7. eCollection 2019. Erratum in: NPJ Syst Biol Appl. 2019 Mar 7;5:11.

7.

Interference Disturbance Analysis Enables Single-Cell Level Growth and Mobility Characterization for Rapid Antimicrobial Susceptibility Testing.

Volbers D, Stierle VK, Ditzel KJ, Aschauer J, Rädler JO, Opitz M, Paulitschke P.

Nano Lett. 2019 Feb 13;19(2):643-651. doi: 10.1021/acs.nanolett.8b02815. Epub 2019 Jan 8.

PMID:
30525694
8.

Probing the Interface Structure of Adhering Cells by Contrast Variation Neutron Reflectometry.

Böhm P, Koutsioubas A, Moulin JF, Rädler JO, Sackmann E, Nickel B.

Langmuir. 2019 Jan 15;35(2):513-521. doi: 10.1021/acs.langmuir.8b02228. Epub 2018 Dec 20.

PMID:
30518215
9.

Corrigendum: Rapid Analysis of Cell-Nanoparticle Interactions using Single-Cell Raman Trapping Microscopy.

Steinke M, Zunhammer F, Chatzopoulou EI, Teller H, Schütze K, Walles H, Rädler JO, Grüttner C.

Angew Chem Int Ed Engl. 2018 Nov 19;57(47):15305. doi: 10.1002/anie.201811554. No abstract available.

PMID:
30412365
10.

Peptide Self-Assembly Measured Using Fluorescence Correlation Spectroscopy.

Mittag JJ, Rädler JO, McManus JJ.

Methods Mol Biol. 2018;1777:159-171. doi: 10.1007/978-1-4939-7811-3_8.

PMID:
29744833
11.

Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing.

Gegenfurtner FA, Jahn B, Wagner H, Ziegenhain C, Enard W, Geistlinger L, Rädler JO, Vollmar AM, Zahler S.

J Cell Sci. 2018 May 29;131(10). pii: jcs212886. doi: 10.1242/jcs.212886.

12.

Nanostructures in n-Octanol Equilibrated with Additives and/or Water.

Cevc G, Berts I, Fischer SF, Rädler JO, Nickel B.

Langmuir. 2018 May 29;34(21):6285-6295. doi: 10.1021/acs.langmuir.8b00142. Epub 2018 May 16.

PMID:
29685034
13.

Single Cell Microarrays Fabricated by Microscale Plasma-Initiated Protein Patterning (μPIPP).

Reiser A, Zorn ML, Murschhauser A, Rädler JO.

Methods Mol Biol. 2018;1771:41-54. doi: 10.1007/978-1-4939-7792-5_4.

PMID:
29633203
14.

Guiding 3D cell migration in deformed synthetic hydrogel microstructures.

Dietrich M, Le Roy H, Brückner DB, Engelke H, Zantl R, Rädler JO, Broedersz CP.

Soft Matter. 2018 Apr 18;14(15):2816-2826. doi: 10.1039/c8sm00018b.

PMID:
29595213
15.

Rapid Analysis of Cell-Nanoparticle Interactions using Single-Cell Raman Trapping Microscopy.

Steinke M, Zunhammer F, Chatzopoulou EI, Teller H, Schütze K, Walles H, Rädler JO, Grüttner C.

Angew Chem Int Ed Engl. 2018 Apr 23;57(18):4946-4950. doi: 10.1002/anie.201713151. Epub 2018 Mar 23. Erratum in: Angew Chem Int Ed Engl. 2018 Nov 19;57(47):15305.

PMID:
29473994
16.

Single-Cell Optical Distortion Correction and Label-Free 3D Cell Shape Reconstruction on Lattices of Nanostructures.

Stephan J, Keber F, Stierle V, Rädler JO, Paulitschke P.

Nano Lett. 2017 Dec 13;17(12):8018-8023. doi: 10.1021/acs.nanolett.7b04651. Epub 2017 Dec 4.

PMID:
29199833
17.

Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines.

Hansjosten I, Rapp J, Reiner L, Vatter R, Fritsch-Decker S, Peravali R, Palosaari T, Joossens E, Gerloff K, Macko P, Whelan M, Gilliland D, Ojea-Jimenez I, Monopoli MP, Rocks L, Garry D, Dawson K, Röttgermann PJF, Murschhauser A, Rädler JO, Tang SVY, Gooden P, Belinga-Desaunay MA, Khan AO, Briffa S, Guggenheim E, Papadiamantis A, Lynch I, Valsami-Jones E, Diabaté S, Weiss C.

Arch Toxicol. 2018 Feb;92(2):633-649. doi: 10.1007/s00204-017-2106-7. Epub 2017 Nov 8.

PMID:
29119250
18.

Kinetic Analysis of the Uptake and Release of Fluorescein by Metal-Organic Framework Nanoparticles.

Preiß T, Zimpel A, Wuttke S, Rädler JO.

Materials (Basel). 2017 Feb 22;10(2). pii: E216. doi: 10.3390/ma10020216.

19.

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia.

Lee DJ, Kessel E, Lehto T, Liu X, Yoshinaga N, Padari K, Chen YC, Kempter S, Uchida S, Rädler JO, Pooga M, Sheu MT, Kataoka K, Wagner E.

Bioconjug Chem. 2017 Sep 20;28(9):2393-2409. doi: 10.1021/acs.bioconjchem.7b00383. Epub 2017 Aug 24.

PMID:
28772071
20.

Impact of plasma protein binding on cargo release by thermosensitive liposomes probed by fluorescence correlation spectroscopy.

Mittag JJ, Kneidl B, Preiβ T, Hossann M, Winter G, Wuttke S, Engelke H, Rädler JO.

Eur J Pharm Biopharm. 2017 Oct;119:215-223. doi: 10.1016/j.ejpb.2017.06.022. Epub 2017 Jun 23.

PMID:
28648864
21.

Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles.

Krzysztoń R, Salem B, Lee DJ, Schwake G, Wagner E, Rädler JO.

Nanoscale. 2017 Jun 8;9(22):7442-7453. doi: 10.1039/c7nr01593c.

PMID:
28530287
22.

Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles.

Morys S, Krhac Levacic A, Urnauer S, Kempter S, Kern S, Rädler JO, Spitzweg C, Lächelt U, Wagner E.

Polymers (Basel). 2017 Apr 19;9(4). pii: E142. doi: 10.3390/polym9040142.

23.

Mutation G1629E Increases von Willebrand Factor Cleavage via a Cooperative Destabilization Mechanism.

Aponte-Santamaría C, Lippok S, Mittag JJ, Obser T, Schneppenheim R, Baldauf C, Gräter F, Budde U, Rädler JO.

Biophys J. 2017 Jan 10;112(1):57-65. doi: 10.1016/j.bpj.2016.11.3202.

24.

Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal-Organic Frameworks.

Röder R, Preiß T, Hirschle P, Steinborn B, Zimpel A, Höhn M, Rädler JO, Bein T, Wagner E, Wuttke S, Lächelt U.

J Am Chem Soc. 2017 Feb 15;139(6):2359-2368. doi: 10.1021/jacs.6b11934. Epub 2017 Feb 6.

PMID:
28075125
25.

Parameter estimation for dynamical systems with discrete events and logical operations.

Fröhlich F, Theis FJ, Rädler JO, Hasenauer J.

Bioinformatics. 2017 Apr 1;33(7):1049-1056. doi: 10.1093/bioinformatics/btw764.

PMID:
28040696
26.

Understanding the Kinetics of Protein-Nanoparticle Corona Formation.

Vilanova O, Mittag JJ, Kelly PM, Milani S, Dawson KA, Rädler JO, Franzese G.

ACS Nano. 2016 Dec 27;10(12):10842-10850. doi: 10.1021/acsnano.6b04858. Epub 2016 Nov 16.

27.

Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells.

Röder R, Helma J, Preiß T, Rädler JO, Leonhardt H, Wagner E.

Pharm Res. 2017 Jan;34(1):161-174. doi: 10.1007/s11095-016-2052-8. Epub 2016 Oct 31.

PMID:
27800572
28.

Time-Resolved Study of Nanoparticle Induced Apoptosis Using Microfabricated Single Cell Arrays.

Röttgermann PJ, Dawson KA, Rädler JO.

Microarrays (Basel). 2016 Apr 15;5(2). pii: E8. doi: 10.3390/microarrays5020008.

29.

Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles.

Westerhausen C, Schnitzler LG, Wendel D, Krzysztoń R, Lächelt U, Wagner E, Rädler JO, Wixforth A.

Micromachines (Basel). 2016 Sep 2;7(9). pii: E150. doi: 10.3390/mi7090150.

30.

Contractility as a global regulator of cellular morphology, velocity, and directionality in low-adhesive fibrillary micro-environments.

Schuster SL, Segerer FJ, Gegenfurtner FA, Kick K, Schreiber C, Albert M, Vollmar AM, Rädler JO, Zahler S.

Biomaterials. 2016 Sep;102:137-47. doi: 10.1016/j.biomaterials.2016.06.021. Epub 2016 Jun 14.

PMID:
27336186
31.

Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes.

Lee DJ, He D, Kessel E, Padari K, Kempter S, Lächelt U, Rädler JO, Pooga M, Wagner E.

J Control Release. 2016 Dec 28;244(Pt B):280-291. doi: 10.1016/j.jconrel.2016.06.011. Epub 2016 Jun 7.

PMID:
27287890
32.

Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration.

Schreiber C, Segerer FJ, Wagner E, Roidl A, Rädler JO.

Sci Rep. 2016 May 31;6:26858. doi: 10.1038/srep26858.

33.

Shape and Interhelical Spacing of DNA Origami Nanostructures Studied by Small-Angle X-ray Scattering.

Fischer S, Hartl C, Frank K, Rädler JO, Liedl T, Nickel B.

Nano Lett. 2016 Jul 13;16(7):4282-7. doi: 10.1021/acs.nanolett.6b01335. Epub 2016 Jun 8.

34.

Internal tension in a collapsed polymer under shear flow and the connection to enzymatic cleavage of von Willebrand factor.

Radtke M, Lippok S, Rädler JO, Netz RR.

Eur Phys J E Soft Matter. 2016 Mar;39(3):32. doi: 10.1140/epje/i2016-16032-7. Epub 2016 Mar 22.

PMID:
26993993
35.

Chip-based platform for dynamic analysis of NK cell cytolysis mediated by a triplebody.

Chatzopoulou EI, Roskopf CC, Sekhavati F, Braciak TA, Fenn NC, Hopfner KP, Oduncu FS, Fey GH, Rädler JO.

Analyst. 2016 Apr 7;141(7):2284-95. doi: 10.1039/c5an02585k.

PMID:
26958659
36.

Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers.

Lippok S, Radtke M, Obser T, Kleemeier L, Schneppenheim R, Budde U, Netz RR, Rädler JO.

Biophys J. 2016 Feb 2;110(3):545-554. doi: 10.1016/j.bpj.2015.12.023.

37.

Versatile method to generate multiple types of micropatterns.

Segerer FJ, Röttgermann PJ, Schuster S, Piera Alberola A, Zahler S, Rädler JO.

Biointerphases. 2016 Mar 22;11(1):011005. doi: 10.1116/1.4940703.

PMID:
26801212
38.

Single-cell characterization of metabolic switching in the sugar phosphotransferase system of Escherichia coli.

Westermayer SA, Fritz G, Gutiérrez J, Megerle JA, Weißl MP, Schnetz K, Gerland U, Rädler JO.

Mol Microbiol. 2016 May;100(3):472-85. doi: 10.1111/mmi.13329. Epub 2016 Feb 19.

39.

von Willebrand factor is dimerized by protein disulfide isomerase.

Lippok S, Kolšek K, Löf A, Eggert D, Vanderlinden W, Müller JP, König G, Obser T, Röhrs K, Schneppenheim S, Budde U, Baldauf C, Aponte-Santamaría C, Gräter F, Schneppenheim R, Rädler JO, Brehm MA.

Blood. 2016 Mar 3;127(9):1183-91. doi: 10.1182/blood-2015-04-641902. Epub 2015 Dec 15.

40.

pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing.

Liu X, Zhang P, He D, Rödl W, Preiß T, Rädler JO, Wagner E, Lächelt U.

Biomacromolecules. 2016 Jan 11;17(1):173-82. doi: 10.1021/acs.biomac.5b01289. Epub 2015 Dec 23.

PMID:
26652751
41.

MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells.

Wuttke S, Braig S, Preiß T, Zimpel A, Sicklinger J, Bellomo C, Rädler JO, Vollmar AM, Bein T.

Chem Commun (Camb). 2015 Nov 11;51(87):15752-5. doi: 10.1039/c5cc06767g.

PMID:
26359316
42.

Stability analysis of chemically modified mRNA using micropattern-based single-cell arrays.

Ferizi M, Leonhardt C, Meggle C, Aneja MK, Rudolph C, Plank C, Rädler JO.

Lab Chip. 2015 Sep 7;15(17):3561-71. doi: 10.1039/c5lc00749f. Epub 2015 Jul 23.

PMID:
26201602
43.

Emergence and Persistence of Collective Cell Migration on Small Circular Micropatterns.

Segerer FJ, Thüroff F, Piera Alberola A, Frey E, Rädler JO.

Phys Rev Lett. 2015 Jun 5;114(22):228102. Epub 2015 Jun 2.

PMID:
26196648
44.

Phenomenological approaches to collective behavior in epithelial cell migration.

Zorn ML, Marel AK, Segerer FJ, Rädler JO.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt B):3143-52. doi: 10.1016/j.bbamcr.2015.05.021. Epub 2015 May 29. Review.

45.

Marker-free detection of progenitor cell differentiation by analysis of Brownian motion in micro-wells.

Sekhavati F, Endele M, Rappl S, Marel AK, Schroeder T, Rädler JO.

Integr Biol (Camb). 2015 Feb;7(2):178-83. doi: 10.1039/c4ib00158c.

PMID:
25514157
46.

Multi-level kinetic model of mRNA delivery via transfection of lipoplexes.

Ligon TS, Leonhardt C, Rädler JO.

PLoS One. 2014 Sep 19;9(9):e107148. doi: 10.1371/journal.pone.0107148. eCollection 2014.

47.

Cell motility on polyethylene glycol block copolymers correlates to fibronectin surface adsorption.

Röttgermann PJ, Hertrich S, Berts I, Albert M, Segerer FJ, Moulin JF, Nickel B, Rädler JO.

Macromol Biosci. 2014 Dec;14(12):1755-63. doi: 10.1002/mabi.201400246. Epub 2014 Sep 10.

PMID:
25204968
48.

Flow and diffusion in channel-guided cell migration.

Marel AK, Zorn M, Klingner C, Wedlich-Söldner R, Frey E, Rädler JO.

Biophys J. 2014 Sep 2;107(5):1054-1064. doi: 10.1016/j.bpj.2014.07.017.

49.

Simultaneous measurement of a range of particle sizes during Aβ1-42 fibrillogenesis quantified using fluorescence correlation spectroscopy.

Mittag JJ, Milani S, Walsh DM, Rädler JO, McManus JJ.

Biochem Biophys Res Commun. 2014 May 30;448(2):195-9. doi: 10.1016/j.bbrc.2014.04.088. Epub 2014 Apr 24.

PMID:
24769478
50.

Cellular self-organization on micro-structured surfaces.

Röttgermann PJ, Alberola AP, Rädler JO.

Soft Matter. 2014 Apr 14;10(14):2397-404. doi: 10.1039/c3sm52419a.

PMID:
24623049

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