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Items: 48


Gram-Negative Pneumonia Augments Non-Small Cell Lung Cancer Metastasis Through Host Toll-like Receptor 4 Activation.

Gowing SD, Chow SC, Cools-Lartigue JJ, Chen CB, Najmeh S, Goodwin-Wilson M, Jiang HY, Bourdeau F, Beauchamp A, Angers I, Giannias B, Spicer JD, Rousseau S, Qureshi ST, Ferri LE.

J Thorac Oncol. 2019 Aug 2. pii: S1556-0864(19)30653-7. doi: 10.1016/j.jtho.2019.07.023. [Epub ahead of print]


Resistance and Tolerance to Cryptococcal Infection: An Intricate Balance That Controls the Development of Disease.

Shourian M, Qureshi ST.

Front Immunol. 2019 Jan 29;10:66. doi: 10.3389/fimmu.2019.00066. eCollection 2019. Review.


Rel-Dependent Immune and Central Nervous System Mechanisms Control Viral Replication and Inflammation during Mouse Herpes Simplex Encephalitis.

Mancini M, Caignard G, Charbonneau B, Dumaine A, Wu N, Leiva-Torres GA, Gerondakis S, Pearson A, Qureshi ST, Sladek R, Vidal SM.

J Immunol. 2019 Mar 1;202(5):1479-1493. doi: 10.4049/jimmunol.1800063. Epub 2019 Jan 25.


Contribution of IL-1RI Signaling to Protection against Cryptococcus neoformans 52D in a Mouse Model of Infection.

Shourian M, Ralph B, Angers I, Sheppard DC, Qureshi ST.

Front Immunol. 2018 Jan 19;8:1987. doi: 10.3389/fimmu.2017.01987. eCollection 2017.


Immune Recognition of Fungal Polysaccharides.

Snarr BD, Qureshi ST, Sheppard DC.

J Fungi (Basel). 2017 Aug 28;3(3). pii: E47. doi: 10.3390/jof3030047. Review.


The TLR4-TRIF pathway can protect against the development of experimental allergic asthma.

Shalaby KH, Al Heialy S, Tsuchiya K, Farahnak S, McGovern TK, Risse PA, Suh WK, Qureshi ST, Martin JG.

Immunology. 2017 Sep;152(1):138-149. doi: 10.1111/imm.12755. Epub 2017 Jun 20.


Radiofrequency radiations induced genotoxic and carcinogenic effects on chickpea (Cicer arietinum L.) root tip cells.

Qureshi ST, Memon SA, Abassi AR, Sial MA, Bughio FA.

Saudi J Biol Sci. 2017 May;24(4):883-891. doi: 10.1016/j.sjbs.2016.02.011. Epub 2016 Feb 11.


Gram-positive pneumonia augments non-small cell lung cancer metastasis via host toll-like receptor 2 activation.

Gowing SD, Chow SC, Cools-Lartigue JJ, Chen CB, Najmeh S, Jiang HY, Bourdeau F, Beauchamp A, Mancini U, Angers I, Giannias B, Spicer JD, Rousseau S, Qureshi ST, Ferri LE.

Int J Cancer. 2017 Aug 1;141(3):561-571. doi: 10.1002/ijc.30734. Epub 2017 May 15.


Regulation of ULK1 Expression and Autophagy by STAT1.

Goldberg AA, Nkengfac B, Sanchez AM, Moroz N, Qureshi ST, Koromilas AE, Wang S, Burelle Y, Hussain SN, Kristof AS.

J Biol Chem. 2017 Feb 3;292(5):1899-1909. doi: 10.1074/jbc.M116.771584. Epub 2016 Dec 23.


Innate Immune B Cell Activation by Leishmania donovani Exacerbates Disease and Mediates Hypergammaglobulinemia.

Silva-Barrios S, Smans M, Duerr CU, Qureshi ST, Fritz JH, Descoteaux A, Stäger S.

Cell Rep. 2016 Jun 14;15(11):2427-37. doi: 10.1016/j.celrep.2016.05.028. Epub 2016 Jun 2.


Divergent impact of Toll-like receptor 2 deficiency on repair mechanisms in healthy muscle versus Duchenne muscular dystrophy.

Mojumdar K, Giordano C, Lemaire C, Liang F, Divangahi M, Qureshi ST, Petrof BJ.

J Pathol. 2016 May;239(1):10-22. doi: 10.1002/path.4689. Epub 2016 Mar 16.


Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells.

Duerr CU, McCarthy CD, Mindt BC, Rubio M, Meli AP, Pothlichet J, Eva MM, Gauchat JF, Qureshi ST, Mazer BD, Mossman KL, Malo D, Gamero AM, Vidal SM, King IL, Sarfati M, Fritz JH.

Nat Immunol. 2016 Jan;17(1):65-75. doi: 10.1038/ni.3308. Epub 2015 Nov 23.


Antiphospholipid antibody-mediated effects in an arterial model of thrombosis are dependent on Toll-like receptor 4.

Laplante P, Fuentes R, Salem D, Subang R, Gillis MA, Hachem A, Farhat N, Qureshi ST, Fletcher CA, Roubey RA, Merhi Y, Thorin É, Levine JS, Mackman N, Rauch J.

Lupus. 2016 Feb;25(2):162-76. doi: 10.1177/0961203315603146. Epub 2015 Sep 21.


The Cnes2 locus on mouse chromosome 17 regulates host defense against cryptococcal infection through pleiotropic effects on host immunity.

Shourian M, Flaczyk A, Angers I, Mindt BC, Fritz JH, Qureshi ST.

Infect Immun. 2015 Dec;83(12):4541-54. doi: 10.1128/IAI.00697-15. Epub 2015 Sep 14.


Unc93b1 -Dependent Endosomal Toll-Like Receptor Signaling Regulates Inflammation and Mortality during Coxsackievirus B3 Infection.

Lafferty EI, Wiltshire SA, Angers I, Vidal SM, Qureshi ST.

J Innate Immun. 2015;7(3):315-30. doi: 10.1159/000369342. Epub 2015 Feb 11.


Gram negative bacteria increase non-small cell lung cancer metastasis via Toll-like receptor 4 activation and mitogen-activated protein kinase phosphorylation.

Chow SC, Gowing SD, Cools-Lartigue JJ, Chen CB, Berube J, Yoon HW, Chan CH, Rousseau MC, Bourdeau F, Giannias B, Roussel L, Qureshi ST, Rousseau S, Ferri LE.

Int J Cancer. 2015 Mar 15;136(6):1341-50. doi: 10.1002/ijc.29111. Epub 2014 Aug 11.


Concomitant exposure to ovalbumin and endotoxin augments airway inflammation but not airway hyperresponsiveness in a murine model of asthma.

Mac Sharry J, Shalaby KH, Marchica C, Farahnak S, Chieh-Li T, Lapthorne S, Qureshi ST, Shanahan F, Martin JG.

PLoS One. 2014 Jun 26;9(6):e98648. doi: 10.1371/journal.pone.0098648. eCollection 2014.


An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.

Lafferty EI, Flaczyk A, Angers I, Homer R, d'Hennezel E, Malo D, Piccirillo CA, Vidal SM, Qureshi ST.

Genes Immun. 2014 Jul-Aug;15(5):320-32. doi: 10.1038/gene.2014.22. Epub 2014 May 22.


Other viral pneumonias: coronavirus, respiratory syncytial virus, adenovirus, hantavirus.

Lee N, Qureshi ST.

Crit Care Clin. 2013 Oct;29(4):1045-68. doi: 10.1016/j.ccc.2013.07.003. Epub 2013 Aug 9. Review.


IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans.

Flaczyk A, Duerr CU, Shourian M, Lafferty EI, Fritz JH, Qureshi ST.

J Immunol. 2013 Sep 1;191(5):2503-13. doi: 10.4049/jimmunol.1300426. Epub 2013 Jul 26.


Inhaled birch pollen extract induces airway hyperresponsiveness via oxidative stress but independently of pollen-intrinsic NADPH oxidase activity, or the TLR4-TRIF pathway.

Shalaby KH, Allard-Coutu A, O'Sullivan MJ, Nakada E, Qureshi ST, Day BJ, Martin JG.

J Immunol. 2013 Jul 15;191(2):922-33. doi: 10.4049/jimmunol.1103644. Epub 2013 Jun 17.


Dose-dependent effects of IL-17 on IL-13-induced airway inflammatory responses and airway hyperresponsiveness.

Kinyanjui MW, Shan J, Nakada EM, Qureshi ST, Fixman ED.

J Immunol. 2013 Apr 15;190(8):3859-68. doi: 10.4049/jimmunol.1200506. Epub 2013 Mar 18.


Susceptibility to progressive Cryptococcus neoformans pulmonary infection is regulated by loci on mouse chromosomes 1 and 9.

Carroll SF, Lafferty EI, Flaczyk A, Fujiwara TM, Homer R, Morgan K, Loredo-Osti JC, Qureshi ST.

Infect Immun. 2012 Dec;80(12):4167-76. doi: 10.1128/IAI.00417-12. Epub 2012 Sep 17.


ICOS-expressing CD4 T cells induced via TLR4 in the nasal mucosa are capable of inhibiting experimental allergic asthma.

Shalaby KH, Jo T, Nakada E, Allard-Coutu A, Tsuchiya K, Hirota N, Qureshi ST, Maghni K, Rioux CR, Martin JG.

J Immunol. 2012 Sep 15;189(6):2793-804. doi: 10.4049/jimmunol.1201194. Epub 2012 Aug 20.


Inhibition of mammalian target of rapamycin augments lipopolysaccharide-induced lung injury and apoptosis.

Fielhaber JA, Carroll SF, Dydensborg AB, Shourian M, Triantafillopoulos A, Harel S, Hussain SN, Bouchard M, Qureshi ST, Kristof AS.

J Immunol. 2012 May 1;188(9):4535-42. doi: 10.4049/jimmunol.1003655. Epub 2012 Mar 26.


The role of toll-like receptors in acute and chronic lung inflammation.

Lafferty EI, Qureshi ST, Schnare M.

J Inflamm (Lond). 2010 Nov 25;7:57. doi: 10.1186/1476-9255-7-57.


Combined Tlr2 and Tlr4 deficiency increases radiation-induced pulmonary fibrosis in mice.

Paun A, Fox J, Balloy V, Chignard M, Qureshi ST, Haston CK.

Int J Radiat Oncol Biol Phys. 2010 Jul 15;77(4):1198-205. doi: 10.1016/j.ijrobp.2009.12.065.


Urotensin II receptor knockout mice on an ApoE knockout background fed a high-fat diet exhibit an enhanced hyperlipidemic and atherosclerotic phenotype.

Bousette N, D'Orleans-Juste P, Kiss RS, You Z, Genest J, Al-Ramli W, Qureshi ST, Gramolini A, Behm D, Ohlstein EH, Harrison SM, Douglas SA, Giaid A.

Circ Res. 2009 Sep 25;105(7):686-95, 19 p following 695. doi: 10.1161/CIRCRESAHA.107.168799. Epub 2009 Aug 20.


Cryptococcus gattii: An Emerging Cause of Fungal Disease in North America.

Dixit A, Carroll SF, Qureshi ST.

Interdiscip Perspect Infect Dis. 2009;2009:840452. doi: 10.1155/2009/840452. Epub 2009 May 25.


Enhanced innate immune responsiveness to pulmonary Cryptococcus neoformans infection is associated with resistance to progressive infection.

Guillot L, Carroll SF, Homer R, Qureshi ST.

Infect Immun. 2008 Oct;76(10):4745-56. doi: 10.1128/IAI.00341-08. Epub 2008 Aug 4.


Sex differences in the genetic architecture of susceptibility to Cryptococcus neoformans pulmonary infection.

Carroll SF, Loredo Osti JC, Guillot L, Morgan K, Qureshi ST.

Genes Immun. 2008 Sep;9(6):536-45. doi: 10.1038/gene.2008.48. Epub 2008 Jun 19.


Chemical mutagenesis: a new strategy against the global threat of infectious diseases.

Richer E, Qureshi ST, Vidal SM, Malo D.

Mamm Genome. 2008 May;19(5):309-17. doi: 10.1007/s00335-008-9114-0. Epub 2008 Jun 17. Review.


Cryptococcus neoformans induces IL-8 secretion and CXCL1 expression by human bronchial epithelial cells.

Guillot L, Carroll SF, Badawy M, Qureshi ST.

Respir Res. 2008 Jan 22;9:9. doi: 10.1186/1465-9921-9-9.


Pasteurella multocida septic shock following liver transplantation treated with drotrecogin alpha (activated).

Al-Sabah S, Goldberg P, Qureshi ST.

Transpl Infect Dis. 2007 Sep;9(3):233-6.


Mammalian model hosts of cryptococcal infection.

Carroll SF, Guillot L, Qureshi ST.

Comp Med. 2007 Feb;57(1):9-17. Review.


Inducible activation of TLR4 confers resistance to hyperoxia-induced pulmonary apoptosis.

Qureshi ST, Zhang X, Aberg E, Bousette N, Giaid A, Shan P, Medzhitov RM, Lee PJ.

J Immunol. 2006 Apr 15;176(8):4950-8.


LPS-hyporesponsiveness of mnd mice is associated with a mutation in Toll-like receptor 4.

Bihl F, Larivière L, Qureshi ST, Flaherty L, Malo D.

Genes Immun. 2001 Feb;2(1):56-9.


The Lps locus: genetic regulation of host responses to bacterial lipopolysaccharide.

Qureshi ST, Gros P, Malo D.

Inflamm Res. 1999 Dec;48(12):613-20. Review.


Functional analysis and chromosomal mapping of Gata5, a gene encoding a zinc finger DNA-binding protein.

Nemer G, Qureshi ST, Malo D, Nemer M.

Mamm Genome. 1999 Oct;10(10):993-9.


Host resistance to infection: genetic control of lipopolysaccharide responsiveness by TOLL-like receptor genes.

Qureshi ST, Gros P, Malo D.

Trends Genet. 1999 Aug;15(8):291-4. Review.


Cutting edge: functional characterization of the effect of the C3H/HeJ defect in mice that lack an Lpsn gene: in vivo evidence for a dominant negative mutation.

Vogel SN, Johnson D, Perera PY, Medvedev A, Larivière L, Qureshi ST, Malo D.

J Immunol. 1999 May 15;162(10):5666-70.


Comparative genomics and host resistance against infectious diseases.

Qureshi ST, Skamene E, Malo D.

Emerg Infect Dis. 1999 Jan-Feb;5(1):36-47. Review.


Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

Qureshi ST, Larivière L, Leveque G, Clermont S, Moore KJ, Gros P, Malo D.

J Exp Med. 1999 Feb 15;189(4):615-25. Erratum in: J Exp Med 1999 May 3;189(9):following 1518.


Mapping of the Gata6 gene to mouse chromosome 18.

Qureshi ST, Bronchain O, Nemer M, Malo D.

Mamm Genome. 1996 Sep;7(9):705-6. No abstract available.


A high-resolution map in the chromosomal region surrounding the Lps locus.

Qureshi ST, Larivière L, Sebastiani G, Clermont S, Skamene E, Gros P, Malo D.

Genomics. 1996 Feb 1;31(3):283-94.


Mouse hepatitis virus-3 induced prothrombinase (Fgl2) maps to proximal chromosome 5.

Qureshi ST, Clermont S, Leibowitz J, Fung LS, Levy G, Malo D.

Genomics. 1995 Sep 1;29(1):307-9. No abstract available.


The murine endoglin gene (Eng) maps to chromosome 2.

Qureshi ST, Gros P, Letarte M, Malo D.

Genomics. 1995 Mar 1;26(1):165-6. No abstract available.


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