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Best matches for Quirós PM[au]:

Mitochondria and Epigenetics - Crosstalk in Homeostasis and Stress. Matilainen O et al. Trends Cell Biol. (2017)

Mitonuclear communication in homeostasis and stress. Quirós PM et al. Nat Rev Mol Cell Biol. (2016)

Analysis of mtDNA/nDNA Ratio in Mice. Quiros PM et al. Curr Protoc Mouse Biol. (2017)

Search results

Items: 30

1.

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.

Bárcena C, Valdés-Mas R, Mayoral P, Garabaya C, Durand S, Rodríguez F, Fernández-García MT, Salazar N, Nogacka AM, Garatachea N, Bossut N, Aprahamian F, Lucia A, Kroemer G, Freije JMP, Quirós PM, López-Otín C.

Nat Med. 2019 Aug;25(8):1234-1242. doi: 10.1038/s41591-019-0504-5. Epub 2019 Jul 22.

PMID:
31332389
2.

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism.

Bárcena C, Quirós PM, Durand S, Mayoral P, Rodríguez F, Caravia XM, Mariño G, Garabaya C, Fernández-García MT, Kroemer G, Freije JMP, López-Otín C.

Cell Rep. 2018 Aug 28;24(9):2392-2403. doi: 10.1016/j.celrep.2018.07.089.

3.

Mitohormesis, an Antiaging Paradigm.

Bárcena C, Mayoral P, Quirós PM.

Int Rev Cell Mol Biol. 2018;340:35-77. doi: 10.1016/bs.ircmb.2018.05.002. Epub 2018 Jun 21. Review.

PMID:
30072093
4.

Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species.

Jha P, McDevitt MT, Gupta R, Quiros PM, Williams EG, Gariani K, Sleiman MB, Diserens L, Jochem A, Ulbrich A, Coon JJ, Auwerx J, Pagliarini DJ.

Cell Syst. 2018 Jun 27;6(6):722-733.e6. doi: 10.1016/j.cels.2018.05.016. Epub 2018 Jun 13.

5.

Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes.

Jha P, McDevitt MT, Halilbasic E, Williams EG, Quiros PM, Gariani K, Sleiman MB, Gupta R, Ulbrich A, Jochem A, Coon JJ, Trauner M, Pagliarini DJ, Auwerx J.

Cell Syst. 2018 Jun 27;6(6):709-721.e6. doi: 10.1016/j.cels.2018.05.009. Epub 2018 Jun 13.

6.

Ablation of the stress protease OMA1 protects against heart failure in mice.

Acin-Perez R, Lechuga-Vieco AV, Del Mar Muñoz M, Nieto-Arellano R, Torroja C, Sánchez-Cabo F, Jiménez C, González-Guerra A, Carrascoso I, Benincá C, Quiros PM, López-Otín C, Castellano JM, Ruíz-Cabello J, Jiménez-Borreguero LJ, Enríquez JA.

Sci Transl Med. 2018 Mar 28;10(434). pii: eaan4935. doi: 10.1126/scitranslmed.aan4935.

PMID:
29593106
7.

Determination of Aconitase Activity: A Substrate of the Mitochondrial Lon Protease.

Quirós PM.

Methods Mol Biol. 2018;1731:49-56. doi: 10.1007/978-1-4939-7595-2_5.

PMID:
29318542
8.

The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress.

Matilainen O, Sleiman MSB, Quiros PM, Garcia SMDA, Auwerx J.

Nat Commun. 2017 Nov 28;8(1):1818. doi: 10.1038/s41467-017-01903-8.

9.

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.

Quirós PM, Prado MA, Zamboni N, D'Amico D, Williams RW, Finley D, Gygi SP, Auwerx J.

J Cell Biol. 2017 Jul 3;216(7):2027-2045. doi: 10.1083/jcb.201702058. Epub 2017 May 31.

10.

Mitochondria and Epigenetics - Crosstalk in Homeostasis and Stress.

Matilainen O, Quirós PM, Auwerx J.

Trends Cell Biol. 2017 Jun;27(6):453-463. doi: 10.1016/j.tcb.2017.02.004. Epub 2017 Mar 6. Review.

PMID:
28274652
11.

Analysis of mtDNA/nDNA Ratio in Mice.

Quiros PM, Goyal A, Jha P, Auwerx J.

Curr Protoc Mouse Biol. 2017 Mar 2;7(1):47-54. doi: 10.1002/cpmo.21.

12.

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.

Merkwirth C, Jovaisaite V, Durieux J, Matilainen O, Jordan SD, Quiros PM, Steffen KK, Williams EG, Mouchiroud L, Tronnes SU, Murillo V, Wolff SC, Shaw RJ, Auwerx J, Dillin A.

Cell. 2016 May 19;165(5):1209-1223. doi: 10.1016/j.cell.2016.04.012. Epub 2016 Apr 28.

13.

Mitonuclear communication in homeostasis and stress.

Quirós PM, Mottis A, Auwerx J.

Nat Rev Mol Cell Biol. 2016 Apr;17(4):213-26. doi: 10.1038/nrm.2016.23. Epub 2016 Mar 9. Review.

PMID:
26956194
14.

Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.

Korwitz A, Merkwirth C, Richter-Dennerlein R, Tröder SE, Sprenger HG, Quirós PM, López-Otín C, Rugarli EI, Langer T.

J Cell Biol. 2016 Jan 18;212(2):157-66. doi: 10.1083/jcb.201507022.

15.

Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia.

Rodríguez D, Bretones G, Quesada V, Villamor N, Arango JR, López-Guillermo A, Ramsay AJ, Baumann T, Quirós PM, Navarro A, Royo C, Martín-Subero JI, Campo E, López-Otín C.

Blood. 2015 Jul 9;126(2):195-202. doi: 10.1182/blood-2014-10-604959. Epub 2015 Jun 1.

16.

New roles for mitochondrial proteases in health, ageing and disease.

Quirós PM, Langer T, López-Otín C.

Nat Rev Mol Cell Biol. 2015 Jun;16(6):345-59. doi: 10.1038/nrm3984. Epub 2015 May 13. Review.

PMID:
25970558
17.

Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research.

Moullan N, Mouchiroud L, Wang X, Ryu D, Williams EG, Mottis A, Jovaisaite V, Frochaux MV, Quiros PM, Deplancke B, Houtkooper RH, Auwerx J.

Cell Rep. 2015 Mar 17;10(10):1681-1691. doi: 10.1016/j.celrep.2015.02.034. Epub 2015 Mar 12.

18.

Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer.

Quirós PM, Bárcena C, López-Otín C.

Mol Cell Oncol. 2014 Dec 31;1(4):e968505. doi: 10.4161/23723548.2014.968505. eCollection 2014 Oct-Dec.

19.

ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity.

Quirós PM, Español Y, Acín-Pérez R, Rodríguez F, Bárcena C, Watanabe K, Calvo E, Loureiro M, Fernández-García MS, Fueyo A, Vázquez J, Enríquez JA, López-Otín C.

Cell Rep. 2014 Jul 24;8(2):542-56. doi: 10.1016/j.celrep.2014.06.018. Epub 2014 Jul 10.

20.

OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury.

Xiao X, Hu Y, Quirós PM, Wei Q, López-Otín C, Dong Z.

Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1318-26. doi: 10.1152/ajprenal.00036.2014. Epub 2014 Mar 26.

21.

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells.

Fontanil T, Rúa S, Llamazares M, Moncada-Pazos A, Quirós PM, García-Suárez O, Vega JA, Sasaki T, Mohamedi Y, Esteban MM, Obaya AJ, Cal S.

Oncotarget. 2014 Mar 15;5(5):1253-64.

22.

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas.

Fraile JM, Ordóñez GR, Quirós PM, Astudillo A, Galván JA, Colomer D, López-Otín C, Freije JM, Puente XS.

Oncotarget. 2013 Nov;4(11):1931-2.

23.

Supercomplex assembly determines electron flux in the mitochondrial electron transport chain.

Lapuente-Brun E, Moreno-Loshuertos R, Acín-Pérez R, Latorre-Pellicer A, Colás C, Balsa E, Perales-Clemente E, Quirós PM, Calvo E, Rodríguez-Hernández MA, Navas P, Cruz R, Carracedo Á, López-Otín C, Pérez-Martos A, Fernández-Silva P, Fernández-Vizarra E, Enríquez JA.

Science. 2013 Jun 28;340(6140):1567-70. doi: 10.1126/science.1230381.

PMID:
23812712
24.

New roles for OMA1 metalloprotease: From mitochondrial proteostasis to metabolic homeostasis.

Quirós PM, Ramsay AJ, López-Otín C.

Adipocyte. 2013 Jan 1;2(1):7-11.

25.

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice.

Quirós PM, Ramsay AJ, Sala D, Fernández-Vizarra E, Rodríguez F, Peinado JR, Fernández-García MS, Vega JA, Enríquez JA, Zorzano A, López-Otín C.

EMBO J. 2012 May 2;31(9):2117-33. doi: 10.1038/emboj.2012.70. Epub 2012 Mar 20.

26.

Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells.

Vazquez-Martin A, Vellon L, Quirós PM, Cufí S, Ruiz de Galarreta E, Oliveras-Ferraros C, Martin AG, Martin-Castillo B, López-Otín C, Menendez JA.

Cell Cycle. 2012 Mar 1;11(5):974-89. doi: 10.4161/cc.11.5.19450. Epub 2012 Mar 1.

PMID:
22333578
27.

Splicing-directed therapy in a new mouse model of human accelerated aging.

Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC, Quirós PM, Bartoli C, Rivera J, Tazi J, Guzmán G, Varela I, Depetris D, de Carlos F, Cobo J, Andrés V, De Sandre-Giovannoli A, Freije JM, Lévy N, López-Otín C.

Sci Transl Med. 2011 Oct 26;3(106):106ra107. doi: 10.1126/scitranslmed.3002847.

28.

Proteomic profiling of adipose tissue from Zmpste24-/- mice, a model of lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing.

Peinado JR, Quirós PM, Pulido MR, Mariño G, Martínez-Chantar ML, Vázquez-Martínez R, Freije JM, López-Otín C, Malagón MM.

Mol Cell Proteomics. 2011 Nov;10(11):M111.008094. doi: 10.1074/mcp.M111.008094. Epub 2011 Aug 9.

29.

Metalloproteases and the degradome.

Ugalde AP, Ordóñez GR, Quirós PM, Puente XS, López-Otín C.

Methods Mol Biol. 2010;622:3-29. doi: 10.1007/978-1-60327-299-5_1.

PMID:
20135273
30.

Premature aging in mice activates a systemic metabolic response involving autophagy induction.

Mariño G, Ugalde AP, Salvador-Montoliu N, Varela I, Quirós PM, Cadiñanos J, van der Pluijm I, Freije JM, López-Otín C.

Hum Mol Genet. 2008 Jul 15;17(14):2196-211. doi: 10.1093/hmg/ddn120. Epub 2008 Apr 28.

PMID:
18443001

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