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Items: 1 to 50 of 143


Dynamic regulation of HIV-1 capsid interaction with the restriction factor TRIM5α identified by magic-angle spinning NMR and molecular dynamics simulations.

Quinn CM, Wang M, Fritz MP, Runge B, Ahn J, Xu C, Perilla JR, Gronenborn AM, Polenova T.

Proc Natl Acad Sci U S A. 2018 Oct 17. pii: 201800796. doi: 10.1073/pnas.1800796115. [Epub ahead of print]


Variability in Pediatric Ideal Body Weight Calculation: Implications for Lung-Protective Mechanical Ventilation Strategies in Pediatric Acute Respiratory Distress Syndrome.

Ward SL, Quinn CM, Steurer MA, Liu KD, Flori HR, Matthay MA.

Pediatr Crit Care Med. 2018 Oct 1. doi: 10.1097/PCC.0000000000001740. [Epub ahead of print]


Overexpression of Fgfr2c causes craniofacial bone hypoplasia and ameliorates craniosynostosis in the Crouzon mouse.

Lee KKL, Peskett E, Quinn CM, Aiello R, Adeeva L, Moulding DA, Stanier P, Pauws E.

Dis Model Mech. 2018 Sep 28. pii: dmm.035311. doi: 10.1242/dmm.035311. [Epub ahead of print]


Fast Magic-Angle Spinning 19 F NMR Spectroscopy of HIV-1 Capsid Protein Assemblies.

Wang M, Lu M, Fritz MP, Quinn CM, Byeon IL, Byeon CH, Struppe J, Maas W, Gronenborn AM, Polenova T.

Angew Chem Int Ed Engl. 2018 Sep 17. doi: 10.1002/anie.201809060. [Epub ahead of print]


Impact of receptor phenotype on nodal burden in patients with breast cancer who have undergone neoadjuvant chemotherapy.

Boland MR, McVeigh TP, O'Flaherty N, Gullo G, Keane M, Quinn CM, McDermott EW, Lowery AJ, Kerin MJ, Prichard RS.

BJS Open. 2017 Jul 31;1(2):39-45. doi: 10.1002/bjs5.6. eCollection 2017 Apr.


Creating Individual Surgeon Performance Assessments in a Statewide Hospital Surgical Quality Improvement Collaborative.

Quinn CM, Bilimoria KY, Chung JW, Ko CY, Cohen ME, Stulberg JJ.

J Am Coll Surg. 2018 Sep;227(3):303-312.e3. doi: 10.1016/j.jamcollsurg.2018.06.002. Epub 2018 Jun 27.


Renal Pre-Competitive Consortium (RPC2): discovering therapeutic targets together.

Tomilo M, Ascani H, Mirel B, Magnone MC, Quinn CM, Karihaloo A, Duffin K, Patel UD, Kretzler M.

Drug Discov Today. 2018 Oct;23(10):1695-1699. doi: 10.1016/j.drudis.2018.05.021. Epub 2018 May 18.


19F Magic Angle Spinning NMR Spectroscopy and Density Functional Theory Calculations of Fluorosubstituted Tryptophans: Integrating Experiment and Theory for Accurate Determination of Chemical Shift Tensors.

Lu M, Sarkar S, Wang M, Kraus J, Fritz M, Quinn CM, Bai S, Holmes ST, Dybowski C, Yap GPA, Struppe J, Sergeyev IV, Maas W, Gronenborn AM, Polenova T.

J Phys Chem B. 2018 Jun 14;122(23):6148-6155. doi: 10.1021/acs.jpcb.8b00377. Epub 2018 May 30.


Determination of accurate backbone chemical shift tensors in microcrystalline proteins by integrating MAS NMR and QM/MM.

Fritz M, Quinn CM, Wang M, Hou G, Lu X, Koharudin LMI, Struppe J, Case DA, Polenova T, Gronenborn AM.

Phys Chem Chem Phys. 2018 Apr 4;20(14):9543-9553. doi: 10.1039/c8cp00647d.


Gender Differences in Utilization of Duty-hour Regulations, Aspects of Burnout, and Psychological Well-being Among General Surgery Residents in the United States.

Dahlke AR, Johnson JK, Greenberg CC, Love R, Kreutzer L, Hewitt DB, Quinn CM, Engelhardt KE, Bilimoria KY.

Ann Surg. 2018 Aug;268(2):204-211. doi: 10.1097/SLA.0000000000002700.


Dual Allosteric Inhibition of SHP2 Phosphatase.

Fodor M, Price E, Wang P, Lu H, Argintaru A, Chen Z, Glick M, Hao HX, Kato M, Koenig R, LaRochelle JR, Liu G, McNeill E, Majumdar D, Nishiguchi GA, Perez LB, Paris G, Quinn CM, Ramsey T, Sendzik M, Shultz MD, Williams SL, Stams T, Blacklow SC, Acker MG, LaMarche MJ.

ACS Chem Biol. 2018 Mar 16;13(3):647-656. doi: 10.1021/acschembio.7b00980. Epub 2018 Jan 18.


Quenching protein dynamics interferes with HIV capsid maturation.

Wang M, Quinn CM, Perilla JR, Zhang H, Shirra R Jr, Hou G, Byeon IJ, Suiter CL, Ablan S, Urano E, Nitz TJ, Aiken C, Freed EO, Zhang P, Schulten K, Gronenborn AM, Polenova T.

Nat Commun. 2017 Nov 24;8(1):1779. doi: 10.1038/s41467-017-01856-y.


NMR of Macromolecular Assemblies and Machines at 1 GHz and Beyond: New Transformative Opportunities for Molecular Structural Biology.

Quinn CM, Wang M, Polenova T.

Methods Mol Biol. 2018;1688:1-35. doi: 10.1007/978-1-4939-7386-6_1. Review.


Estimation of Population Average Treatment Effects in the FIRST Trial: Application of a Propensity Score-Based Stratification Approach.

Chung JW, Bilimoria KY, Stulberg JJ, Quinn CM, Hedges LV.

Health Serv Res. 2017 Aug 21. doi: 10.1111/1475-6773.12752. [Epub ahead of print]


Expanding the horizons for structural analysis of fully protonated protein assemblies by NMR spectroscopy at MAS frequencies above 100 kHz.

Struppe J, Quinn CM, Lu M, Wang M, Hou G, Lu X, Kraus J, Andreas LB, Stanek J, Lalli D, Lesage A, Pintacuda G, Maas W, Gronenborn AM, Polenova T.

Solid State Nucl Magn Reson. 2017 Oct;87:117-125. doi: 10.1016/j.ssnmr.2017.07.001. Epub 2017 Jul 3.


Comparison of Oncotype DX® Recurrence Score® with other risk assessment tools including the Nottingham Prognostic Index in the identification of patients with low-risk invasive breast cancer.

Cotter MB, Dakin A, Maguire A, Walshe JM, Kennedy MJ, Dunne B, Riain CÓ, Quinn CM.

Virchows Arch. 2017 Sep;471(3):321-328. doi: 10.1007/s00428-017-2184-1. Epub 2017 Jul 14.


Surgical Residents' Work Hours and Well-Being in Year 2 of the FIRST Trial.

Dahlke AR, Quinn CM, Chung JW, Bilimoria KY.

N Engl J Med. 2017 Jul 13;377(2):192-194. doi: 10.1056/NEJMc1703812. No abstract available.


Structural biology of supramolecular assemblies by magic-angle spinning NMR spectroscopy.

Quinn CM, Polenova T.

Q Rev Biophys. 2017 Jan;50:e1. doi: 10.1017/S0033583516000159. Review.


Toward Closing the Gap: Quantum Mechanical Calculations and Experimentally Measured Chemical Shifts of a Microcrystalline Lectin.

Fritz M, Quinn CM, Wang M, Hou G, Lu X, Koharudin LMI, Polenova T, Gronenborn AM.

J Phys Chem B. 2017 Apr 20;121(15):3574-3585. doi: 10.1021/acs.jpcb.6b09479. Epub 2016 Dec 21.


Use and Underlying Reasons for Duty Hour Flexibility in the Flexibility in Duty Hour Requirements for Surgical Trainees (FIRST) Trial.

Bilimoria KY, Quinn CM, Dahlke AR, Kelz RR, Shea JA, Rajaram R, Love R, Kreutzer L, Biester T, Yang AD, Hoyt DB, Lewis FR.

J Am Coll Surg. 2017 Feb;224(2):118-125. doi: 10.1016/j.jamcollsurg.2016.10.046. Epub 2016 Nov 21.


Gender-Based Differences in Surgical Residents' Perceptions of Patient Safety, Continuity of Care, and Well-Being: An Analysis from the Flexibility in Duty Hour Requirements for Surgical Trainees (FIRST) Trial.

Ban KA, Chung JW, Matulewicz RS, Kelz RR, Shea JA, Dahlke AR, Quinn CM, Yang AD, Bilimoria KY.

J Am Coll Surg. 2017 Feb;224(2):126-136.e2. doi: 10.1016/j.jamcollsurg.2016.10.043. Epub 2016 Nov 21.


Association Between Flexible Duty Hour Policies and General Surgery Resident Examination Performance: A Flexibility in Duty Hour Requirements for Surgical Trainees (FIRST) Trial Analysis.

Blay E Jr, Hewitt DB, Chung JW, Biester T, Fiore JF, Dahlke AR, Quinn CM, Lewis FR, Bilimoria KY.

J Am Coll Surg. 2017 Feb;224(2):137-142. doi: 10.1016/j.jamcollsurg.2016.10.042. Epub 2016 Nov 21.


Differences in Resident Perceptions by Postgraduate Year of Duty Hour Policies: An Analysis from the Flexibility in Duty Hour Requirements for Surgical Trainees (FIRST) Trial.

Yang AD, Chung JW, Dahlke AR, Biester T, Quinn CM, Matulewicz RS, Odell DD, Kelz RR, Shea JA, Lewis F, Bilimoria KY.

J Am Coll Surg. 2017 Feb;224(2):103-112. doi: 10.1016/j.jamcollsurg.2016.10.045. Epub 2016 Nov 4.


Cross-sector analysis of socioeconomic, racial/ethnic, and urban/rural disparities in food policy enactment in the United States.

Taber DR, Chriqui JF, Quinn CM, Rimkus LM, Chaloupka FJ.

Health Place. 2016 Nov;42:47-53. doi: 10.1016/j.healthplace.2016.08.006. Epub 2016 Sep 14.


Poor Adherence to Lung-Protective Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome.

Ward SL, Quinn CM, Valentine SL, Sapru A, Curley MA, Willson DF, Liu KD, Matthay MA, Flori HR.

Pediatr Crit Care Med. 2016 Oct;17(10):917-923.


Inhibition of T-cell activation by the CTLA4-Fc Abatacept is sufficient to ameliorate proteinuric kidney disease.

Herrera M, Söderberg M, Sabirsh A, Valastro B, Mölne J, Santamaria B, Valverde AM, Guionaud S, Heasman S, Bigley A, Jermutus L, Rondinone C, Coghlan M, Baker D, Quinn CM.

Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F748-F759. doi: 10.1152/ajprenal.00179.2016. Epub 2016 Jul 20.


A Positive Node on Ultrasound-Guided Fine Needle Aspiration Predicts Higher Nodal Burden Than a Positive Sentinel Lymph Node Biopsy in Breast Carcinoma.

Boland MR, Ni Cearbhaill R, Fitzpatrick K, Walsh SM, Evoy D, Geraghty J, Rothwell J, McNally S, O'Doherty A, Quinn CM, McDermott EW, Prichard RS.

World J Surg. 2016 Sep;40(9):2157-62. doi: 10.1007/s00268-016-3557-3.


Role of bone scan in addition to CT in patients with breast cancer selected for systemic staging.

McCartan DP, Prichard RS, MacDermott RJ, Rothwell J, Geraghty J, Evoy D, Quinn CM, Skehan SJ, O'Doherty A, McDermott EW.

Br J Surg. 2016 Jun;103(7):839-44. doi: 10.1002/bjs.10124. Epub 2016 Mar 23.


Altered hypothalamic inflammatory gene expression correlates with heat stroke severity in a conscious rodent model.

Audet GN, Dineen SM, Quinn CM, Leon LR.

Brain Res. 2016 Apr 15;1637:81-90. doi: 10.1016/j.brainres.2016.01.048. Epub 2016 Feb 12.


Consistency in recognizing microinvasion in breast carcinomas is improved by immunohistochemistry for myoepithelial markers.

Cserni G, Wells CA, Kaya H, Regitnig P, Sapino A, Floris G, Decker T, Foschini MP, van Diest PJ, Grabau D, Reiner A, DeGaetano J, Chmielik E, Cordoba A, Andreu X, Zolota V, Charafe-Jauffret E, Ryska A, Varga Z, Weingertner N, Bellocq JP, Liepniece-Karele I, Callagy G, Kulka J, Bürger H, Figueiredo P, Wesseling J, Amendoeira I, Faverly D, Quinn CM, Bianchi S.

Virchows Arch. 2016 Apr;468(4):473-81. doi: 10.1007/s00428-016-1909-x. Epub 2016 Jan 27.


New ASCO/CAP guideline recommendations for HER2 testing increase the proportion of reflex in situ hybridization tests and of HER2 positive breast cancers.

Tchrakian N, Flanagan L, Harford J, Gannon JM, Quinn CM.

Virchows Arch. 2016 Feb;468(2):207-11. doi: 10.1007/s00428-015-1871-z. Epub 2015 Oct 31.


Point-of-care cardiac troponin test accurately predicts heat stroke severity in rats.

Audet GN, Quinn CM, Leon LR.

Am J Physiol Regul Integr Comp Physiol. 2015 Nov 15;309(10):R1264-72. doi: 10.1152/ajpregu.00286.2015. Epub 2015 Aug 19.


Photoactivatable genetically encoded calcium indicators for targeted neuronal imaging.

Berlin S, Carroll EC, Newman ZL, Okada HO, Quinn CM, Kallman B, Rockwell NC, Martin SS, Lagarias JC, Isacoff EY.

Nat Methods. 2015 Sep;12(9):852-8. doi: 10.1038/nmeth.3480. Epub 2015 Jul 13.


Delineating transcriptional networks of prognostic gene signatures refines treatment recommendations for lymph node-negative breast cancer patients.

Lanigan F, Brien GL, Fan Y, Madden SF, Jerman E, Maratha A, Aloraifi F, Hokamp K, Dunne EJ, Lohan AJ, Flanagan L, Garbe JC, Stampfer MR, Fridberg M, Jirstrom K, Quinn CM, Loftus B, Gallagher WM, Geraghty J, Bracken AP.

FEBS J. 2015 Sep;282(18):3455-73. doi: 10.1111/febs.13354. Epub 2015 Jul 14.


Cardiovascular and thermoregulatory dysregulation over 24 h following acute heat stress in rats.

Quinn CM, Audet GN, Charkoudian N, Leon LR.

Am J Physiol Heart Circ Physiol. 2015 Aug 15;309(4):H557-64. doi: 10.1152/ajpheart.00918.2014. Epub 2015 Jun 12.


Magic angle spinning NMR of viruses.

Quinn CM, Lu M, Suiter CL, Hou G, Zhang H, Polenova T.

Prog Nucl Magn Reson Spectrosc. 2015 Apr;86-87:21-40. doi: 10.1016/j.pnmrs.2015.02.003. Epub 2015 Feb 16. Review.


MAS NMR of HIV-1 protein assemblies.

Suiter CL, Quinn CM, Lu M, Hou G, Zhang H, Polenova T.

J Magn Reson. 2015 Apr;253:10-22. doi: 10.1016/j.jmr.2014.12.009.


Phenotypic analysis of familial breast cancer: comparison of BRCAx tumors with BRCA1-, BRCA2-carriers and non-familial breast cancer.

Aloraifi F, Alshehhi M, McDevitt T, Cody N, Meany M, O'Doherty A, Quinn CM, Green AJ, Bracken A, Geraghty JG.

Eur J Surg Oncol. 2015 May;41(5):641-6. doi: 10.1016/j.ejso.2015.01.021. Epub 2015 Feb 17.


Axillary nodal burden in primary breast cancer patients with positive pre-operative ultrasound guided fine needle aspiration cytology: management in the era of ACOSOG Z011.

Boland MR, Prichard RS, Daskalova I, Lowery AJ, Evoy D, Geraghty J, Rothwell J, Quinn CM, O'Doherty A, McDermott EW.

Eur J Surg Oncol. 2015 Apr;41(4):559-65. doi: 10.1016/j.ejso.2015.01.011. Epub 2015 Jan 24.


HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export.

Du XM, Kim MJ, Hou L, Le Goff W, Chapman MJ, Van Eck M, Curtiss LK, Burnett JR, Cartland SP, Quinn CM, Kockx M, Kontush A, Rye KA, Kritharides L, Jessup W.

Circ Res. 2015 Mar 27;116(7):1133-42. doi: 10.1161/CIRCRESAHA.116.305485. Epub 2015 Jan 14. Erratum in: Circ Res. 2015 Jul 17;117(3):e40.


ABCG1 is involved in vitamin E efflux.

Olivier M, BottG R, Frisdal E, Nowick M, Plengpanich W, Desmarchelier C, Roi S, Quinn CM, Gelissen I, Jessup W, Van Eck M, Guérin M, Le Goff W, Reboul E.

Biochim Biophys Acta. 2014 Dec;1841(12):1741-51.


Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages.

Traini M, Quinn CM, Sandoval C, Johansson E, Schroder K, Kockx M, Meikle PJ, Jessup W, Kritharides L.

J Biol Chem. 2014 Nov 21;289(47):32895-913. doi: 10.1074/jbc.M114.612341. Epub 2014 Oct 6.


Cardiovascular and thermoregulatory biomarkers of heat stroke severity in a conscious rat model.

Quinn CM, Duran RM, Audet GN, Charkoudian N, Leon LR.

J Appl Physiol (1985). 2014 Nov 1;117(9):971-8. doi: 10.1152/japplphysiol.00365.2014. Epub 2014 Aug 14.


Development and Reliability Testing of a Fast-Food Restaurant Observation Form.

Rimkus L, Ohri-Vachaspati P, Powell LM, Zenk SN, Quinn CM, Barker DC, Pugach O, Resnick EA, Chaloupka FJ.

Am J Health Promot. 2015 Sep-Oct;30(1):9-18. doi: 10.4278/ajhp.130731-QUAN-389. Epub 2014 May 12.


Enzyme-dependent lysine deprotonation in EZH2 catalysis.

Kipp DR, Quinn CM, Fortin PD.

Biochemistry. 2013 Oct 1;52(39):6866-78. doi: 10.1021/bi400805w. Epub 2013 Sep 18.


The classification of invasive carcinoma of the breast.

Gannon LM, Cotter MB, Quinn CM.

Expert Rev Anticancer Ther. 2013 Aug;13(8):941-54. doi: 10.1586/14737140.2013.820577. Review.


Development and reliability testing of a food store observation form.

Rimkus L, Powell LM, Zenk SN, Han E, Ohri-Vachaspati P, Pugach O, Barker DC, Resnick EA, Quinn CM, Myllyluoma J, Chaloupka FJ.

J Nutr Educ Behav. 2013 Nov-Dec;45(6):540-8. doi: 10.1016/j.jneb.2013.02.005. Epub 2013 May 30.


High-grade histologic features of DCIS are associated with R5 rather than R3 calcifications in breast screening mammography.

Hayes BD, Brodie C, O'Doherty A, Quinn CM.

Breast J. 2013 May-Jun;19(3):319-24. doi: 10.1111/tbj.12106. Epub 2013 Apr 18.


Microinvasive lobular carcinoma arising in a fibroadenoma.

Hayes BD, Quinn CM.

Int J Surg Pathol. 2013 Aug;21(4):419-21. doi: 10.1177/1066896912471854. Epub 2013 Jan 24.


Quantifying conformational dynamics using solid-state R₁ρ experiments.

Quinn CM, McDermott AE.

J Magn Reson. 2012 Sep;222:1-7. doi: 10.1016/j.jmr.2012.05.014. Epub 2012 May 29.

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