Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 70

1.

Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.

Kallander LS, Washburn D, Hilfiker MA, Eidam HS, Lawhorn BG, Prendergast J, Fox R, Dowdell S, Manns S, Hoang T, Zhao S, Ye G, Hammond M, Holt DA, Roethke T, Hong X, Reid RA, Gampe R, Zhang H, Diaz E, Rendina AR, Quinn AM, Willette B.

ACS Med Chem Lett. 2018 Jul 2;9(7):736-740. doi: 10.1021/acsmedchemlett.8b00173. eCollection 2018 Jul 12.

PMID:
30034610
2.

Assay for Detecting Gαi-Mediated Decreases in cAMP in Living Cells.

Tewson P, Martinka S, Shaner N, Berlot C, Quinn AM, Hughes T.

SLAS Discov. 2018 Jul 1:2472555218786238. doi: 10.1177/2472555218786238. [Epub ahead of print]

PMID:
29991302
3.

Clinical and Pathologic Characteristics of Pulmonary Carcinoid Tumors in Central and Peripheral Locations.

Papaxoinis G, Lamarca A, Quinn AM, Mansoor W, Nonaka D.

Endocr Pathol. 2018 May 16. doi: 10.1007/s12022-018-9530-y. [Epub ahead of print]

PMID:
29770932
4.

The plasma interleukin-6 response to acute psychosocial stress in humans is detected by a magnetic multiplex assay: comparison to high-sensitivity ELISA.

Quinn AM, Williams AR, Sivilli TI, Raison CL, Pace TWW.

Stress. 2018 Mar 13:1-6. doi: 10.1080/10253890.2018.1446518. [Epub ahead of print]

PMID:
29529950
5.

Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

Abbosh C, Birkbak NJ, Wilson GA, Jamal-Hanjani M, Constantin T, Salari R, Le Quesne J, Moore DA, Veeriah S, Rosenthal R, Marafioti T, Kirkizlar E, Watkins TBK, McGranahan N, Ward S, Martinson L, Riley J, Fraioli F, Al Bakir M, Grönroos E, Zambrana F, Endozo R, Bi WL, Fennessy FM, Sponer N, Johnson D, Laycock J, Shafi S, Czyzewska-Khan J, Rowan A, Chambers T, Matthews N, Turajlic S, Hiley C, Lee SM, Forster MD, Ahmad T, Falzon M, Borg E, Lawrence D, Hayward M, Kolvekar S, Panagiotopoulos N, Janes SM, Thakrar R, Ahmed A, Blackhall F, Summers Y, Hafez D, Naik A, Ganguly A, Kareht S, Shah R, Joseph L, Quinn AM, Crosbie PA, Naidu B, Middleton G, Langman G, Trotter S, Nicolson M, Remmen H, Kerr K, Chetty M, Gomersall L, Fennell DA, Nakas A, Rathinam S, Anand G, Khan S, Russell P, Ezhil V, Ismail B, Irvin-Sellers M, Prakash V, Lester JF, Kornaszewska M, Attanoos R, Adams H, Davies H, Oukrif D, Akarca AU, Hartley JA, Lowe HL, Lock S, Iles N, Bell H, Ngai Y, Elgar G, Szallasi Z, Schwarz RF, Herrero J, Stewart A, Quezada SA, Peggs KS, Van Loo P, Dive C, Lin CJ, Rabinowitz M, Aerts HJWL, Hackshaw A, Shaw JA, Zimmermann BG, Swanton C.

Nature. 2018 Feb 8;554(7691):264. doi: 10.1038/nature25161. Epub 2017 Dec 20.

PMID:
29258292
6.

A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1.

McNulty DE, Bonnette WG, Qi H, Wang L, Ho TF, Waszkiewicz A, Kallal LA, Nagarajan RP, Stern M, Quinn AM, Creasy CL, Su DS, Graves AP, Annan RS, Sweitzer SM, Holbert MA.

SLAS Discov. 2018 Jan;23(1):34-46. doi: 10.1177/2472555217732014. Epub 2017 Sep 28.

PMID:
28957646
7.

Tracking the Evolution of Non-Small-Cell Lung Cancer.

Jamal-Hanjani M, Wilson GA, McGranahan N, Birkbak NJ, Watkins TBK, Veeriah S, Shafi S, Johnson DH, Mitter R, Rosenthal R, Salm M, Horswell S, Escudero M, Matthews N, Rowan A, Chambers T, Moore DA, Turajlic S, Xu H, Lee SM, Forster MD, Ahmad T, Hiley CT, Abbosh C, Falzon M, Borg E, Marafioti T, Lawrence D, Hayward M, Kolvekar S, Panagiotopoulos N, Janes SM, Thakrar R, Ahmed A, Blackhall F, Summers Y, Shah R, Joseph L, Quinn AM, Crosbie PA, Naidu B, Middleton G, Langman G, Trotter S, Nicolson M, Remmen H, Kerr K, Chetty M, Gomersall L, Fennell DA, Nakas A, Rathinam S, Anand G, Khan S, Russell P, Ezhil V, Ismail B, Irvin-Sellers M, Prakash V, Lester JF, Kornaszewska M, Attanoos R, Adams H, Davies H, Dentro S, Taniere P, O'Sullivan B, Lowe HL, Hartley JA, Iles N, Bell H, Ngai Y, Shaw JA, Herrero J, Szallasi Z, Schwarz RF, Stewart A, Quezada SA, Le Quesne J, Van Loo P, Dive C, Hackshaw A, Swanton C; TRACERx Consortium.

N Engl J Med. 2017 Jun 1;376(22):2109-2121. doi: 10.1056/NEJMoa1616288. Epub 2017 Apr 26.

8.

Agreement between cytotechnologists and cytopathologists as a new measure of cytopathologist performance in gynecologic cytology.

Quinn AM, Minhajuddin AT, Hynan LS, Reisch JS, Cibas ES.

Cancer Cytopathol. 2017 Jul;125(7):576-580. doi: 10.1002/cncy.21856. Epub 2017 Mar 27.

9.

Outcomes after mitral valve repair: A single-center 16-year experience.

Tatum JM, Bowdish ME, Mack WJ, Quinn AM, Cohen RG, Hackmann AE, Barr ML, Starnes VA.

J Thorac Cardiovasc Surg. 2017 Sep;154(3):822-830.e2. doi: 10.1016/j.jtcvs.2017.01.047. Epub 2017 Feb 9.

PMID:
28283230
10.

Metastatic Melanoma to the Bladder: Case Report and Review of the Literature.

Patil RV, Woldu SL, Lucas E, Quinn AM, Francis F, Margulis V.

Urol Case Rep. 2017 Jan 10;11:33-36. doi: 10.1016/j.eucr.2016.10.017. eCollection 2017 Feb.

11.

High-grade Neuroendocrine Carcinoma of the Lung With Carcinoid Morphology: A Study of 12 Cases.

Quinn AM, Chaturvedi A, Nonaka D.

Am J Surg Pathol. 2017 Feb;41(2):263-270. doi: 10.1097/PAS.0000000000000767.

PMID:
27879513
12.

Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics.

Moore BS, Stepanchick AN, Tewson PH, Hartle CM, Zhang J, Quinn AM, Hughes TE, Mirshahi T.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13069-13074. Epub 2016 Oct 31.

13.

Bagpipe lung; a new type of interstitial lung disease?

King J, Richardson M, Quinn AM, Holme J, Chaudhuri N.

Thorax. 2017 Apr;72(4):380-382. doi: 10.1136/thoraxjnl-2016-208751. Epub 2016 Aug 22. No abstract available.

PMID:
27552781
14.

Decision Support and Shared Decision Making About Active Surveillance Versus Active Treatment Among Men Diagnosed with Low-Risk Prostate Cancer: a Pilot Study.

Myers RE, Leader AE, Censits JH, Trabulsi EJ, Keith SW, Petrich AM, Quinn AM, Den RB, Hurwitz MD, Lallas CD, Hegarty SE, Dicker AP, Zeigler-Johnson CM, Giri VN, Ayaz H, Gomella LG.

J Cancer Educ. 2018 Feb;33(1):180-185. doi: 10.1007/s13187-016-1073-7.

PMID:
27418065
15.

Arsenite accumulation in the mouse eye.

Kleiman NJ, Quinn AM, Fields KG, Slavkovich V, Graziano JH.

J Toxicol Environ Health A. 2016;79(8):339-41. doi: 10.1080/15287394.2016.1151392.

16.

Blatant ignorance.

Chong BS, Berman AM, Billis G, Quinn AM, Emery CD, Filippo GD, Duncan HF, Schäfer E, Chandler NP.

Br Dent J. 2016 Feb 12;220(3):90-1. doi: 10.1038/sj.bdj.2016.71. No abstract available.

PMID:
26868778
17.

New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories.

Tewson PH, Martinka S, Shaner NC, Hughes TE, Quinn AM.

J Biomol Screen. 2016 Mar;21(3):298-305. doi: 10.1177/1087057115618608. Epub 2015 Dec 11.

18.

Environmental components and methods for engaging pathology residents in informatics training.

Garcia CA, Baron JM, Beckwith BA, Brodsky V, Dighe AS, Gudewicz TM, Kim JY, Klepeis VE, Lane WJ, Lee RE, Levy BP, Mahowald MA, Mandelker D, McClintock DS, Quinn AM, Rao LK, Riedlinger GM, Rudolf J, Gilbertson JR.

J Pathol Inform. 2015 Jun 29;6:42. eCollection 2015. No abstract available.

19.

In-vitro characterisation of a novel celecoxib microbead formulation for the treatment and prevention of colorectal cancer.

McDonald BF, Quinn AM, Devers T, Cullen A, Coulter IS, Marison IW, Loughran ST.

J Pharm Pharmacol. 2015 May;67(5):685-95. doi: 10.1111/jphp.12372. Epub 2015 Feb 3.

PMID:
25650335
20.

Diagnostic Mutation Profiling and Validation of Non-Small-Cell Lung Cancer Small Biopsy Samples using a High Throughput Platform.

Quinn AM, Hickson N, Adaway M, Priest L, Jaeger E, Udar N, Keeling C, Kamieniorz M, Dive C, Wallace A, Byers RJ, Newman WG, Nonaka D, Blackhall FH.

J Thorac Oncol. 2015 May;10(5):784-92. doi: 10.1097/JTO.0000000000000473.

21.

Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange.

Ding Y, Li J, Enterina JR, Shen Y, Zhang I, Tewson PH, Mo GC, Zhang J, Quinn AM, Hughes TE, Maysinger D, Alford SC, Zhang Y, Campbell RE.

Nat Methods. 2015 Mar;12(3):195-8. doi: 10.1038/nmeth.3261. Epub 2015 Jan 26.

22.

The ongoing evolution of the core curriculum of a clinical fellowship in pathology informatics.

Quinn AM, Klepeis VE, Mandelker DL, Platt MY, Rao LK, Riedlinger G, Baron JM, Brodsky V, Kim JY, Lane W, Lee RE, Levy BP, McClintock DS, Beckwith BA, Kuo FC, Gilbertson JR.

J Pathol Inform. 2014 Jul 30;5(1):22. doi: 10.4103/2153-3539.137717. eCollection 2014.

23.

Intrapopulation genome size variation in D. melanogaster reflects life history variation and plasticity.

Ellis LL, Huang W, Quinn AM, Ahuja A, Alfrejd B, Gomez FE, Hjelmen CE, Moore KL, Mackay TF, Johnston JS, Tarone AM.

PLoS Genet. 2014 Jul 24;10(7):e1004522. doi: 10.1371/journal.pgen.1004522. eCollection 2014 Jul.

24.

PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity.

Chen X, Egly C, Riley AM, Li W, Tewson P, Hughes TE, Quinn AM, Obukhov AG.

Cells. 2014 Apr 4;3(2):247-57. doi: 10.3390/cells3020247.

25.

The 2013 symposium on pathology data integration and clinical decision support and the current state of field.

Baron JM, Dighe AS, Arnaout R, Balis UJ, Black-Schaffer WS, Carter AB, Henricks WH, Higgins JM, Jackson BR, Kim J, Klepeis VE, Le LP, Louis DN, Mandelker D, Mermel CH, Michaelson JS, Nagarajan R, Platt ME, Quinn AM, Rao L, Shirts BH, Gilbertson JR.

J Pathol Inform. 2014 Jan 31;5(1):2. doi: 10.4103/2153-3539.126145. eCollection 2014.

26.

A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth.

Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Peña-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, Easmon J, Martinez ED.

Nat Commun. 2013;4:2035. doi: 10.1038/ncomms3035. Erratum in: Nat Commun. 2013;4:2639.

27.

A multiplexed fluorescent assay for independent second-messenger systems: decoding GPCR activation in living cells.

Tewson PH, Quinn AM, Hughes TE.

J Biomol Screen. 2013 Aug;18(7):797-806. doi: 10.1177/1087057113485427. Epub 2013 Apr 11.

28.

Polypectomy is adequate treatment for adenoma-like dysplastic lesions (DALMs) in Crohn's disease.

Quinn AM, Farraye FA, Naini BV, Cerda S, Coukos J, Li Y, Khor T, Odze RD.

Inflamm Bowel Dis. 2013 May;19(6):1186-93. doi: 10.1097/MIB.0b013e318280e749.

PMID:
23567776
29.

Simultaneous detection of Ca2+ and diacylglycerol signaling in living cells.

Tewson P, Westenberg M, Zhao Y, Campbell RE, Quinn AM, Hughes TE.

PLoS One. 2012;7(8):e42791. doi: 10.1371/journal.pone.0042791. Epub 2012 Aug 17. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/108decc5-1a4a-4fa7-a867-d6cfaea8f471.

30.

Extrapulmonary small cell carcinoma: a clinicopathological study with identification of potential diagnostic mimics.

Quinn AM, Blackhall F, Wilson G, Danson S, Clamp A, Ashcroft L, Brierley J, Hasleton P.

Histopathology. 2012 Sep;61(3):454-64. doi: 10.1111/j.1365-2559.2012.04247.x. Epub 2012 Jun 11.

PMID:
22687056
31.

Differences in the in vitro and in vivo pharmacokinetic profiles of once-daily modified-release methylphenidate formulations in Canada: examination of current bioequivalence criteria.

Shram MJ, Quinn AM, Chen N, Faulknor J, Luong D, Sellers EM, Endrenyi L.

Clin Ther. 2012 May;34(5):1170-81. doi: 10.1016/j.clinthera.2012.02.010. Epub 2012 Apr 17.

PMID:
22512898
32.

Perspectives on the discovery of small-molecule modulators for epigenetic processes.

Lu Q, Quinn AM, Patel MP, Semus SF, Graves AP, Bandyopadhyay D, Pope AJ, Thrall SH.

J Biomol Screen. 2012 Jun;17(5):555-71. doi: 10.1177/1087057112437763. Epub 2012 Mar 5. Review.

PMID:
22392809
33.

Methods for Activity Analysis of the Proteins that Regulate Histone Methylation.

Quinn AM, Simeonov A.

Curr Chem Genomics. 2011;5(Suppl 1):95-105. doi: 10.2174/1875397301005010095. Epub 2011 Aug 22.

34.

Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.

Shultz CA, Quinn AM, Park JH, Harvey RG, Bolton JL, Maser E, Penning TM.

Chem Res Toxicol. 2011 Dec 19;24(12):2153-66. doi: 10.1021/tx200294c. Epub 2011 Sep 29.

35.

Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors.

King ON, Li XS, Sakurai M, Kawamura A, Rose NR, Ng SS, Quinn AM, Rai G, Mott BT, Beswick P, Klose RJ, Oppermann U, Jadhav A, Heightman TD, Maloney DJ, Schofield CJ, Simeonov A.

PLoS One. 2010 Nov 23;5(11):e15535. doi: 10.1371/journal.pone.0015535.

36.

Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines.

Liu F, Chen X, Allali-Hassani A, Quinn AM, Wigle TJ, Wasney GA, Dong A, Senisterra G, Chau I, Siarheyeva A, Norris JL, Kireev DB, Jadhav A, Herold JM, Janzen WP, Arrowsmith CH, Frye SV, Brown PJ, Simeonov A, Vedadi M, Jin J.

J Med Chem. 2010 Aug 12;53(15):5844-57. doi: 10.1021/jm100478y.

37.

Nature of the energy landscape for gated electron transfer in a dynamic redox protein.

Hay S, Brenner S, Khara B, Quinn AM, Rigby SE, Scrutton NS.

J Am Chem Soc. 2010 Jul 21;132(28):9738-45. doi: 10.1021/ja1016206.

PMID:
20572660
38.

A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors.

Quinn AM, Allali-Hassani A, Vedadi M, Simeonov A.

Mol Biosyst. 2010 May;6(5):782-8. doi: 10.1039/b921912a. Epub 2010 Mar 2.

39.

A highly potent and selective caspase 1 inhibitor that utilizes a key 3-cyanopropanoic acid moiety.

Boxer MB, Quinn AM, Shen M, Jadhav A, Leister W, Simeonov A, Auld DS, Thomas CJ.

ChemMedChem. 2010 May 3;5(5):730-8. doi: 10.1002/cmdc.200900531.

40.

A miniaturized screen for inhibitors of Jumonji histone demethylases.

Sakurai M, Rose NR, Schultz L, Quinn AM, Jadhav A, Ng SS, Oppermann U, Schofield CJ, Simeonov A.

Mol Biosyst. 2010 Feb;6(2):357-64. doi: 10.1039/b912993f. Epub 2009 Oct 8.

41.

A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics.

Quinn AM, Bedford MT, Espejo A, Spannhoff A, Austin CP, Oppermann U, Simeonov A.

Nucleic Acids Res. 2010 Jan;38(2):e11. doi: 10.1093/nar/gkp899. Epub 2009 Nov 6.

42.

Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.

Liu F, Chen X, Allali-Hassani A, Quinn AM, Wasney GA, Dong A, Barsyte D, Kozieradzki I, Senisterra G, Chau I, Siarheyeva A, Kireev DB, Jadhav A, Herold JM, Frye SV, Arrowsmith CH, Brown PJ, Simeonov A, Vedadi M, Jin J.

J Med Chem. 2009 Dec 24;52(24):7950-3. doi: 10.1021/jm901543m.

43.

A prospective comparison of diaphragmatic ultrasound and chest radiography to determine endotracheal tube position in a pediatric emergency department.

Kerrey BT, Geis GL, Quinn AM, Hornung RW, Ruddy RM.

Pediatrics. 2009 Jun;123(6):e1039-44. doi: 10.1542/peds.2008-2828. Epub 2009 May 4.

PMID:
19414520
44.

Internal electron transfer in multi-site redox enzymes is accessed by laser excitation of thiouredopyrene-3,6,8-trisulfonate (TUPS).

Heyes DJ, Quinn AM, Cullis PM, Lee M, Munro AW, Scrutton NS.

Chem Commun (Camb). 2009 Mar 7;(9):1124-6. doi: 10.1039/b820386e. Epub 2009 Jan 12.

PMID:
19225657
45.

Oxidation of PAH trans-dihydrodiols by human aldo-keto reductase AKR1B10.

Quinn AM, Harvey RG, Penning TM.

Chem Res Toxicol. 2008 Nov;21(11):2207-15. doi: 10.1021/tx8002005.

46.

Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells.

Park JH, Mangal D, Tacka KA, Quinn AM, Harvey RG, Blair IA, Penning TM.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):6846-51. doi: 10.1073/pnas.0802776105. Epub 2008 May 12.

47.
48.

Tissue array construction: pitfalls, problems, and progress.

Quinn AM, Tang P, Yang Q, Bourne PA.

Appl Immunohistochem Mol Morphol. 2008 May;16(3):287-90. doi: 10.1097/PAI.0b013e31814b2fe2.

PMID:
18301239
49.

Determination of ultrafilterable prolactin: elimination of macroprolactin interference with a monomeric prolactin-selective sample pretreatment.

Quinn AM, Rubinas TC, Garbincius CJ, Holmes EW.

Arch Pathol Lab Med. 2006 Dec;130(12):1807-12.

PMID:
17149954
50.

Clear cell sarcoma of the small bowel: a potential pitfall. Case report.

Venkataraman G, Quinn AM, Williams J, Hammadeh R.

APMIS. 2005 Oct;113(10):716-9.

PMID:
16309433

Supplemental Content

Loading ...
Support Center