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Items: 45

1.

Cardiac interstitial tetraploid cells can escape replicative senescence in rodents but not large mammals.

Broughton KM, Khieu T, Nguyen N, Rosa M, Mohsin S, Quijada P, Wang BJ, Echeagaray OH, Kubli DA, Kim T, Firouzi F, Monsanto MM, Gude NA, Adamson RM, Dembitsky WP, Davis ME, Sussman MA.

Commun Biol. 2019 Jun 13;2:205. doi: 10.1038/s42003-019-0453-z. eCollection 2019.

2.

Pre-existing fibroblasts of epicardial origin are the primary source of pathological fibrosis in cardiac ischemia and aging.

Quijada P, Misra A, Velasquez LS, Burke RM, Lighthouse JK, Mickelsen DM, Dirkx RA Jr, Small EM.

J Mol Cell Cardiol. 2019 Apr;129:92-104. doi: 10.1016/j.yjmcc.2019.01.015. Epub 2019 Feb 13.

PMID:
30771308
3.

Platelet-derived β2M regulates monocyte inflammatory responses.

Hilt ZT, Pariser DN, Ture SK, Mohan A, Quijada P, Asante AA, Cameron SJ, Sterling JA, Merkel AR, Johanson AL, Jenkins JL, Small EM, McGrath KE, Palis J, Elliott MR, Morrell CN.

JCI Insight. 2019 Mar 7;4(5). pii: 122943. doi: 10.1172/jci.insight.122943. eCollection 2019 Mar 7.

4.

Cardiomyocyte cell cycle dynamics and proliferation revealed through cardiac-specific transgenesis of fluorescent ubiquitinated cell cycle indicator (FUCCI).

Alvarez R Jr, Wang BJ, Quijada PJ, Avitabile D, Ho T, Shaitrit M, Chavarria M, Firouzi F, Ebeid D, Monsanto MM, Navarrete N, Moshref M, Siddiqi S, Broughton KM, Bailey BA, Gude NA, Sussman MA.

J Mol Cell Cardiol. 2019 Feb;127:154-164. doi: 10.1016/j.yjmcc.2018.12.007. Epub 2018 Dec 18.

PMID:
30571978
5.

Mechanosensitive Gene Regulation by Myocardin-Related Transcription Factors Is Required for Cardiomyocyte Integrity in Load-Induced Ventricular Hypertrophy.

Trembley MA, Quijada P, Agullo-Pascual E, Tylock KM, Colpan M, Dirkx RA Jr, Myers JR, Mickelsen DM, de Mesy Bentley K, Rothenberg E, Moravec CS, Alexis JD, Gregorio CC, Dirksen RT, Delmar M, Small EM.

Circulation. 2018 Oct 23;138(17):1864-1878. doi: 10.1161/CIRCULATIONAHA.117.031788.

6.

Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.

Burke RM, Lighthouse JK, Quijada P, Dirkx RA Jr, Rosenberg A, Moravec CS, Alexis JD, Small EM.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3436-E3445. doi: 10.1073/pnas.1717423115. Epub 2018 Mar 26.

7.

Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate.

Matsumoto C, Jiang Y, Emathinger J, Quijada P, Nguyen N, De La Torre A, Moshref M, Nguyen J, Levinson AB, Shin M, Sussman MA, Hariharan N.

Stem Cells. 2018 Jun;36(6):868-880. doi: 10.1002/stem.2793. Epub 2018 Feb 25.

8.

PIM1-minicircle as a therapeutic treatment for myocardial infarction.

Liu N, Wang BJ, Broughton KM, Alvarez R, Siddiqi S, Loaiza R, Nguyen N, Quijada P, Gude N, Sussman MA.

PLoS One. 2017 Mar 21;12(3):e0173963. doi: 10.1371/journal.pone.0173963. eCollection 2017.

9.

S100A4 protects the myocardium against ischemic stress.

Doroudgar S, Quijada P, Konstandin M, Ilves K, Broughton K, Khalafalla FG, Casillas A, Nguyen K, Gude N, Toko H, Ornelas L, Thuerauf DJ, Glembotski CC, Sussman MA, Völkers M.

J Mol Cell Cardiol. 2016 Nov;100:54-63. doi: 10.1016/j.yjmcc.2016.10.001. Epub 2016 Oct 6.

10.

Secondary coenzyme Q10 deficiencies in oxidative phosphorylation (OXPHOS) and non-OXPHOS disorders.

Yubero D, Montero R, Martín MA, Montoya J, Ribes A, Grazina M, Trevisson E, Rodriguez-Aguilera JC, Hargreaves IP, Salviati L, Navas P, Artuch R; CoQ deficiency study group, Jou C, Jimenez-Mallebrera C, Nascimento A, Pérez-Dueñas B, Ortez C, Ramos F, Colomer J, O'Callaghan M, Pineda M, García-Cazorla A, Espinós C, Ruiz A, Macaya A, Marcé-Grau A, Garcia-Villoria J, Arias A, Emperador S, Ruiz-Pesini E, Lopez-Gallardo E, Neergheen V, Simões M, Diogo L, Blázquez A, González-Quintana A, Delmiro A, Domínguez-González C, Arenas J, García-Silva MT, Martín E, Quijada P, Hernández-Laín A, Morán M, Rivas Infante E, Ávila Polo R, Paradas Lópe C, Bautista Lorite J, Martínez Fernández EM, Cortés AB, Sánchez-Cuesta A, Cascajo MV, Alcázar M, Brea-Calvo G.

Mitochondrion. 2016 Sep;30:51-8. doi: 10.1016/j.mito.2016.06.007. Epub 2016 Jun 30.

PMID:
27374853
11.

Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment.

Quijada P, Hariharan N, Cubillo JD, Bala KM, Emathinger JM, Wang BJ, Ormachea L, Bers DM, Sussman MA, Poizat C.

J Biol Chem. 2015 Oct 16;290(42):25411-26. doi: 10.1074/jbc.M115.657775. Epub 2015 Aug 31.

12.

Cardiac Stem Cell Hybrids Enhance Myocardial Repair.

Quijada P, Salunga HT, Hariharan N, Cubillo JD, El-Sayed FG, Moshref M, Bala KM, Emathinger JM, De La Torre A, Ormachea L, Alvarez R Jr, Gude NA, Sussman MA.

Circ Res. 2015 Sep 25;117(8):695-706. doi: 10.1161/CIRCRESAHA.115.306838. Epub 2015 Jul 30.

13.

Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy.

Wade F, Quijada P, Al-Haffar KM, Awad SM, Kunhi M, Toko H, Marashly Q, Belhaj K, Zahid I, Al-Mohanna F, Stanford SM, Alvarez R, Liu Y, Colak D, Jordan MC, Roos KP, Assiri A, Al-Habeeb W, Sussman M, Bottini N, Poizat C.

J Pathol. 2015 Dec;237(4):482-94. doi: 10.1002/path.4594. Epub 2015 Sep 1.

14.

Notch activation enhances lineage commitment and protective signaling in cardiac progenitor cells.

Gude N, Joyo E, Toko H, Quijada P, Villanueva M, Hariharan N, Sacchi V, Truffa S, Joyo A, Voelkers M, Alvarez R, Sussman MA.

Basic Res Cardiol. 2015 May;110(3):29. doi: 10.1007/s00395-015-0488-3. Epub 2015 Apr 19.

15.

Functional Effect of Pim1 Depends upon Intracellular Localization in Human Cardiac Progenitor Cells.

Samse K, Emathinger J, Hariharan N, Quijada P, Ilves K, Völkers M, Ormachea L, De La Torre A, Orogo AM, Alvarez R, Din S, Mohsin S, Monsanto M, Fischer KM, Dembitsky WP, Gustafsson ÅB, Sussman MA.

J Biol Chem. 2015 May 29;290(22):13935-47. doi: 10.1074/jbc.M114.617431. Epub 2015 Apr 16.

16.

Circulating around the tissue: hematopoietic cell-based fusion versus transdifferentiation.

Quijada P, Sussman MA.

Circ Res. 2015 Feb 13;116(4):563-5. doi: 10.1161/CIRCRESAHA.115.305820. No abstract available.

17.

Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging.

Hariharan N, Quijada P, Mohsin S, Joyo A, Samse K, Monsanto M, De La Torre A, Avitabile D, Ormachea L, McGregor MJ, Tsai EJ, Sussman MA.

J Am Coll Cardiol. 2015 Jan 20;65(2):133-47. doi: 10.1016/j.jacc.2014.09.086.

18.

Control of histone H3 phosphorylation by CaMKIIδ in response to haemodynamic cardiac stress.

Awad S, Al-Haffar KM, Marashly Q, Quijada P, Kunhi M, Al-Yacoub N, Wade FS, Mohammed SF, Al-Dayel F, Sutherland G, Assiri A, Sussman M, Bers D, Al-Habeeb W, Poizat C.

J Pathol. 2015 Mar;235(4):606-18. doi: 10.1002/path.4489. Epub 2014 Dec 17.

19.

Making it stick: chasing the optimal stem cells for cardiac regeneration.

Quijada P, Sussman MA.

Expert Rev Cardiovasc Ther. 2014 Nov;12(11):1275-88. doi: 10.1586/14779072.2014.972941. Review.

20.

PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity.

Völkers M, Doroudgar S, Nguyen N, Konstandin MH, Quijada P, Din S, Ornelas L, Thuerauf DJ, Gude N, Friedrich K, Herzig S, Glembotski CC, Sussman MA.

EMBO Mol Med. 2014 Jan;6(1):57-65. doi: 10.1002/emmm.201303183.

21.

Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage.

Völkers M, Konstandin MH, Doroudgar S, Toko H, Quijada P, Din S, Joyo A, Ornelas L, Samse K, Thuerauf DJ, Gude N, Glembotski CC, Sussman MA.

Circulation. 2013 Nov 5;128(19):2132-44. doi: 10.1161/CIRCULATIONAHA.113.003638. Epub 2013 Sep 5.

22.

Fibronectin contributes to pathological cardiac hypertrophy but not physiological growth.

Konstandin MH, Völkers M, Collins B, Quijada P, Quintana M, De La Torre A, Ormachea L, Din S, Gude N, Toko H, Sussman MA.

Basic Res Cardiol. 2013 Sep;108(5):375. doi: 10.1007/s00395-013-0375-8. Epub 2013 Aug 4.

23.

Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1.

Völkers M, Toko H, Doroudgar S, Din S, Quijada P, Joyo AY, Ornelas L, Joyo E, Thuerauf DJ, Konstandin MH, Gude N, Glembotski CC, Sussman MA.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12661-6. doi: 10.1073/pnas.1301455110. Epub 2013 Jul 10.

24.

Fibronectin is essential for reparative cardiac progenitor cell response after myocardial infarction.

Konstandin MH, Toko H, Gastelum GM, Quijada P, De La Torre A, Quintana M, Collins B, Din S, Avitabile D, Völkers M, Gude N, Fässler R, Sussman MA.

Circ Res. 2013 Jul 5;113(2):115-25. doi: 10.1161/CIRCRESAHA.113.301152. Epub 2013 May 7.

25.

Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation.

Din S, Mason M, Völkers M, Johnson B, Cottage CT, Wang Z, Joyo AY, Quijada P, Erhardt P, Magnuson NS, Konstandin MH, Sussman MA.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5969-74. doi: 10.1073/pnas.1213294110. Epub 2013 Mar 25.

26.

β-Adrenergic regulation of cardiac progenitor cell death versus survival and proliferation.

Khan M, Mohsin S, Avitabile D, Siddiqi S, Nguyen J, Wallach K, Quijada P, McGregor M, Gude N, Alvarez R, Tilley DG, Koch WJ, Sussman MA.

Circ Res. 2013 Feb 1;112(3):476-86. doi: 10.1161/CIRCRESAHA.112.280735. Epub 2012 Dec 14.

27.

Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair.

Mohsin S, Khan M, Toko H, Bailey B, Cottage CT, Wallach K, Nag D, Lee A, Siddiqi S, Lan F, Fischer KM, Gude N, Quijada P, Avitabile D, Truffa S, Collins B, Dembitsky W, Wu JC, Sussman MA.

J Am Coll Cardiol. 2012 Oct 2;60(14):1278-87. doi: 10.1016/j.jacc.2012.04.047. Epub 2012 Jul 26.

28.

Preservation of myocardial structure is enhanced by pim-1 engineering of bone marrow cells.

Quijada P, Toko H, Fischer KM, Bailey B, Reilly P, Hunt KD, Gude NA, Avitabile D, Sussman MA.

Circ Res. 2012 Jun 22;111(1):77-86. doi: 10.1161/CIRCRESAHA.112.265207. Epub 2012 May 22.

29.

Myocardial AKT: the omnipresent nexus.

Sussman MA, Völkers M, Fischer K, Bailey B, Cottage CT, Din S, Gude N, Avitabile D, Alvarez R, Sundararaman B, Quijada P, Mason M, Konstandin MH, Malhowski A, Cheng Z, Khan M, McGregor M.

Physiol Rev. 2011 Jul;91(3):1023-70. doi: 10.1152/physrev.00024.2010. Review.

30.

Cardiac progenitor cell commitment is inhibited by nuclear Akt expression.

Fischer KM, Din S, Gude N, Konstandin MH, Wu W, Quijada P, Sussman MA.

Circ Res. 2011 Apr 15;108(8):960-70. doi: 10.1161/CIRCRESAHA.110.237156. Epub 2011 Feb 24.

31.

Kearns-Sayre syndrome: cerebral folate deficiency, MRI findings and new cerebrospinal fluid biochemical features.

Serrano M, García-Silva MT, Martin-Hernandez E, O'Callaghan Mdel M, Quijada P, Martinez-Aragón A, Ormazábal A, Blázquez A, Martín MA, Briones P, López-Gallardo E, Ruiz-Pesini E, Montoya J, Artuch R, Pineda M.

Mitochondrion. 2010 Aug;10(5):429-32. doi: 10.1016/j.mito.2010.04.001. Epub 2010 Apr 11.

PMID:
20388557
32.

Pim-1 kinase protects mitochondrial integrity in cardiomyocytes.

Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, Gustafsson AB, Miyamoto S, Glembotski CC, Gottlieb RA, Brown JH, Sussman MA.

Circ Res. 2010 Apr 16;106(7):1265-74. doi: 10.1161/CIRCRESAHA.109.212035. Epub 2010 Mar 4.

33.

Cardiac progenitor cell cycling stimulated by pim-1 kinase.

Cottage CT, Bailey B, Fischer KM, Avitabile D, Collins B, Tuck S, Quijada P, Gude N, Alvarez R, Muraski J, Sussman MA.

Circ Res. 2010 Mar 19;106(5):891-901. doi: 10.1161/CIRCRESAHA.109.208629. Epub 2010 Jan 14. Erratum in: Circ Res. 2015 Nov 6;117(11):e90. Avitable, Daniele [corrected to Avitabile, Daniele]. Endocr Pract. 2015 May;21(5):559.

34.

Cardiac stem cell genetic engineering using the alphaMHC promoter.

Bailey B, Izarra A, Alvarez R, Fischer KM, Cottage CT, Quijada P, Díez-Juan A, Sussman MA.

Regen Med. 2009 Nov;4(6):823-33. doi: 10.2217/rme.09.51.

35.

Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase.

Fischer KM, Cottage CT, Wu W, Din S, Gude NA, Avitabile D, Quijada P, Collins BL, Fransioli J, Sussman MA.

Circulation. 2009 Nov 24;120(21):2077-87. doi: 10.1161/CIRCULATIONAHA.109.884403. Epub 2009 Nov 9.

36.

Successful early fascial closure of an open abdomen during pregnancy.

Pappas PA, Cheatham ML, Quijada P, O'Leary T, Carlan SJ.

Am Surg. 2009 Feb;75(2):183-4. No abstract available.

PMID:
19280818
37.

Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload.

Muraski JA, Fischer KM, Wu W, Cottage CT, Quijada P, Mason M, Din S, Gude N, Alvarez R Jr, Rota M, Kajstura J, Wang Z, Schaefer E, Chen X, MacDonnel S, Magnuson N, Houser SR, Anversa P, Sussman MA.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13889-94. doi: 10.1073/pnas.0709135105. Epub 2008 Sep 10.

38.

Activation of Notch-mediated protective signaling in the myocardium.

Gude NA, Emmanuel G, Wu W, Cottage CT, Fischer K, Quijada P, Muraski JA, Alvarez R, Rubio M, Schaefer E, Sussman MA.

Circ Res. 2008 May 9;102(9):1025-35. doi: 10.1161/CIRCRESAHA.107.164749. Epub 2008 Mar 27.

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41.

A distant upstream enhancer at the maize domestication gene tb1 has pleiotropic effects on plant and inflorescent architecture.

Clark RM, Wagler TN, Quijada P, Doebley J.

Nat Genet. 2006 May;38(5):594-7. Epub 2006 Apr 23.

PMID:
16642024
42.

Quantitative trait loci for resistance to Sclerotinia sclerotiorum and its association with a homeologous non-reciprocal transposition in Brassica napus L.

Zhao J, Udall JA, Quijada PA, Grau CR, Meng J, Osborn TC.

Theor Appl Genet. 2006 Feb;112(3):509-16. Epub 2005 Dec 7.

PMID:
16333614
43.
44.

Characterization and effects of the replicated flowering time gene FLC in Brassica rapa.

Schranz ME, Quijada P, Sung SB, Lukens L, Amasino R, Osborn TC.

Genetics. 2002 Nov;162(3):1457-68.

45.

[Arteriovenous shunt and fistula for chronic hemodialysis].

Reyes J, Quijada P.

Rev Med Chil. 1971 May;99(5):353-6. Spanish. No abstract available.

PMID:
5097304

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