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Items: 26

1.

Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane.

Ruiz-Guillen M, Gabev E, Quetglas JI, Casales E, Ballesteros-Briones MC, Poutou J, Aranda A, Martisova E, Bezunartea J, Ondiviela M, Prieto J, Hernandez-Alcoceba R, Abrescia NG, Smerdou C.

Cell Mol Life Sci. 2016 Oct;73(20):3897-916. doi: 10.1007/s00018-016-2230-1. Epub 2016 Apr 27.

PMID:
27117550
2.

A Simple and Efficient In Vivo Non-viral RNA Transfection Method for Labeling the Whole Axonal Tree of Individual Adult Long-Range Projection Neurons.

Porrero C, Rodríguez-Moreno J, Quetglas JI, Smerdou C, Furuta T, Clascá F.

Front Neuroanat. 2016 Mar 18;10:27. doi: 10.3389/fnana.2016.00027. eCollection 2016.

3.

Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism.

Labiano S, Palazón A, Bolaños E, Azpilikueta A, Sánchez-Paulete AR, Morales-Kastresana A, Quetglas JI, Perez-Gracia JL, Gúrpide A, Rodriguez-Ruiz M, Aznar MA, Jure-Kunkel M, Berraondo P, Melero I.

Oncoimmunology. 2015 Jun 24;5(1):e1062967. eCollection 2016.

4.

Enhanced therapeutic effect using sequential administration of antigenically distinct oncolytic viruses expressing oncostatin M in a Syrian hamster orthotopic pancreatic cancer model.

Nistal-Villan E, Bunuales M, Poutou J, Gonzalez-Aparicio M, Bravo-Perez C, Quetglas JI, Carte B, Gonzalez-Aseguinolaza G, Prieto J, Larrea E, Hernandez-Alcoceba R.

Mol Cancer. 2015 Dec 16;14:210. doi: 10.1186/s12943-015-0479-x.

5.

Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells.

Sánchez-Paulete AR, Cueto FJ, Martínez-López M, Labiano S, Morales-Kastresana A, Rodríguez-Ruiz ME, Jure-Kunkel M, Azpilikueta A, Aznar MA, Quetglas JI, Sancho D, Melero I.

Cancer Discov. 2016 Jan;6(1):71-9. doi: 10.1158/2159-8290.CD-15-0510. Epub 2015 Oct 22.

6.

Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb.

Weigelin B, Bolaños E, Teijeira A, Martinez-Forero I, Labiano S, Azpilikueta A, Morales-Kastresana A, Quetglas JI, Wagena E, Sánchez-Paulete AR, Chen L, Friedl P, Melero I.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7551-6. doi: 10.1073/pnas.1506357112. Epub 2015 Jun 1.

7.

Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model.

Poutou J, Bunuales M, Gonzalez-Aparicio M, Garcia-Aragoncillo E, Quetglas JI, Casado R, Bravo-Perez C, Alzuguren P, Hernandez-Alcoceba R.

Gene Ther. 2015 Sep;22(9):696-706. doi: 10.1038/gt.2015.45. Epub 2015 May 4.

PMID:
25938192
8.

Virotherapy with a Semliki Forest Virus-Based Vector Encoding IL12 Synergizes with PD-1/PD-L1 Blockade.

Quetglas JI, Labiano S, Aznar MÁ, Bolaños E, Azpilikueta A, Rodriguez I, Casales E, Sánchez-Paulete AR, Segura V, Smerdou C, Melero I.

Cancer Immunol Res. 2015 May;3(5):449-54. doi: 10.1158/2326-6066.CIR-14-0216. Epub 2015 Feb 17.

9.

Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12.

Melero I, Quetglas JI, Reboredo M, Dubrot J, Rodriguez-Madoz JR, Mancheño U, Casales E, Riezu-Boj JI, Ruiz-Guillen M, Ochoa MC, Sanmamed MF, Thieblemont N, Smerdou C, Hervas-Stubbs S.

Cancer Res. 2015 Feb 1;75(3):497-507. doi: 10.1158/0008-5472.CAN-13-3356. Epub 2014 Dec 19.

10.
11.

Better performance of CARs deprived of the PD-1 brake.

Morales-Kastresana A, Labiano S, Quetglas JI, Melero I.

Clin Cancer Res. 2013 Oct 15;19(20):5546-8. doi: 10.1158/1078-0432.CCR-13-2157. Epub 2013 Sep 4.

12.

The immunological profile of tumor-bearing animals determines the outcome of cancer immunotherapy.

Quetglas JI, Hervas-Stubbs S, Smerdou C.

Oncoimmunology. 2013 Jun 1;2(6):e24499. Epub 2013 Apr 16.

13.

Eradication of liver-implanted tumors by Semliki Forest virus expressing IL-12 requires efficient long-term immune responses.

Quetglas JI, Rodriguez-Madoz JR, Bezunartea J, Ruiz-Guillen M, Casales E, Medina-Echeverz J, Prieto J, Berraondo P, Hervas-Stubbs S, Smerdou C.

J Immunol. 2013 Mar 15;190(6):2994-3004. doi: 10.4049/jimmunol.1201791. Epub 2013 Feb 11.

14.

Virotherapy, gene transfer and immunostimulatory monoclonal antibodies.

Quetglas JI, John LB, Kershaw MH, Alvarez-Vallina L, Melero I, Darcy PK, Smerdou C.

Oncoimmunology. 2012 Nov 1;1(8):1344-1354.

15.

Antibodies against Marinobacter algicola and Salmonella typhimurium flagellins do not cross-neutralize TLR5 activation.

Terron-Exposito R, Dudognon B, Galindo I, Quetglas JI, Coll JM, Escribano JM, Gomez-Casado E.

PLoS One. 2012;7(11):e48466. doi: 10.1371/journal.pone.0048466. Epub 2012 Nov 14.

16.

Endosomal maturation, Rab7 GTPase and phosphoinositides in African swine fever virus entry.

Cuesta-Geijo MA, Galindo I, Hernáez B, Quetglas JI, Dalmau-Mena I, Alonso C.

PLoS One. 2012;7(11):e48853. doi: 10.1371/journal.pone.0048853. Epub 2012 Nov 1.

17.

Evaluation of monocytes as carriers for armed oncolytic adenoviruses in murine and Syrian hamster models of cancer.

Bunuales M, Garcia-Aragoncillo E, Casado R, Quetglas JI, Hervas-Stubbs S, Bortolanza S, Benavides-Vallve C, Ortiz-de-Solorzano C, Prieto J, Hernandez-Alcoceba R.

Hum Gene Ther. 2012 Dec;23(12):1258-68. doi: 10.1089/hum.2012.043. Epub 2012 Oct 26.

18.

Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic Semliki Forest virus encoding IL-12.

Quetglas JI, Dubrot J, Bezunartea J, Sanmamed MF, Hervas-Stubbs S, Smerdou C, Melero I.

Mol Ther. 2012 Sep;20(9):1664-75. doi: 10.1038/mt.2012.56. Epub 2012 Jun 26.

19.

Recent patents on alphavirus protein expression and vector production.

Aranda A, Ruiz-Guillen M, Quetglas JI, Bezunartea J, Casales E, Smerdou C.

Recent Pat Biotechnol. 2011 Dec;5(3):212-26. Review.

PMID:
22360469
20.

Small rho GTPases and cholesterol biosynthetic pathway intermediates in African swine fever virus infection.

Quetglas JI, Hernáez B, Galindo I, Muñoz-Moreno R, Cuesta-Geijo MA, Alonso C.

J Virol. 2012 Feb;86(3):1758-67. doi: 10.1128/JVI.05666-11. Epub 2011 Nov 23.

21.

A Semliki forest virus vector engineered to express IFNα induces efficient elimination of established tumors.

Quetglas JI, Fioravanti J, Ardaiz N, Medina-Echeverz J, Baraibar I, Prieto J, Smerdou C, Berraondo P.

Gene Ther. 2012 Mar;19(3):271-8. doi: 10.1038/gt.2011.99. Epub 2011 Jul 7.

PMID:
21734727
22.

Alphavirus vectors for cancer therapy.

Quetglas JI, Ruiz-Guillen M, Aranda A, Casales E, Bezunartea J, Smerdou C.

Virus Res. 2010 Nov;153(2):179-96. doi: 10.1016/j.virusres.2010.07.027. Epub 2010 Aug 6. Review.

PMID:
20692305
23.

Immunology and gene therapy: shoulder to shoulder into the fray.

Smerdou C, Ochoa C, Quetglas JI, Fontanellas A, Gonzalez-Aseguinolaza G, Vile RG, Melero I.

Mol Ther. 2010 Mar;18(3):456-9. doi: 10.1038/mt.2010.7. No abstract available.

24.

A novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector.

Casales E, Aranda A, Quetglas JI, Ruiz-Guillen M, Rodriguez-Madoz JR, Prieto J, Smerdou C.

N Biotechnol. 2010 May 31;27(2):138-48. doi: 10.1016/j.nbt.2010.02.005. Epub 2010 Feb 24.

PMID:
20188220
25.

Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.

Rodriguez-Madoz JR, Liu KH, Quetglas JI, Ruiz-Guillen M, Otano I, Crettaz J, Butler SD, Bellezza CA, Dykes NL, Tennant BC, Prieto J, González-Aseguinolaza G, Smerdou C, Menne S.

J Virol. 2009 Dec;83(23):12266-78. doi: 10.1128/JVI.01597-09. Epub 2009 Sep 9.

26.

Protein pE120R of African swine fever virus is post-translationally acetylated as revealed by post-source decay MALDI mass spectrometry.

Alfonso P, Quetglas JI, Escribano JM, Alonso C.

Virus Genes. 2007 Aug;35(1):81-5. Epub 2006 Sep 9.

PMID:
16964554

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