Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51

1.

Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension.

Agbor LN, Nair AR, Wu J, Lu KT, Davis DR, Keen HL, Quelle FW, McCormick JA, Singer JD, Sigmund CD.

JCI Insight. 2019 Jun 11;5. pii: 129793. doi: 10.1172/jci.insight.129793.

2.

RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity.

Mukohda M, Fang S, Wu J, Agbor LN, Nair AR, Ibeawuchi SC, Hu C, Liu X, Lu KT, Guo DF, Davis DR, Keen HL, Quelle FW, Sigmund CD.

J Clin Invest. 2019 Mar 21;129(6):2318-2332. doi: 10.1172/JCI123462.

3.

RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth.

Umesalma S, Kaemmer CA, Kohlmeyer JL, Letney B, Schab AM, Reilly JA, Sheehy RM, Hagen J, Tiwari N, Zhan F, Leidinger MR, O'Dorisio TM, Dillon J, Merrill RA, Meyerholz DK, Perl AL, Brown BJ, Braun TA, Scott AT, Ginader T, Taghiyev AF, Zamba GK, Howe JR, Strack S, Bellizzi AM, Narla G, Darbro BW, Quelle FW, Quelle DE.

J Clin Invest. 2019 Mar 4;130:1641-1653. doi: 10.1172/JCI123049. eCollection 2019 Mar 4.

4.

PPARγ and retinol binding protein 7 form a regulatory hub promoting antioxidant properties of the endothelium.

Woll AW, Quelle FW, Sigmund CD.

Physiol Genomics. 2017 Nov 1;49(11):653-658. doi: 10.1152/physiolgenomics.00055.2017. Epub 2017 Sep 15. Review.

5.

Hypertension-Causing Mutation in Peroxisome Proliferator-Activated Receptor γ Impairs Nuclear Export of Nuclear Factor-κB p65 in Vascular Smooth Muscle.

Mukohda M, Lu KT, Guo DF, Wu J, Keen HL, Liu X, Ketsawatsomkron P, Stump M, Rahmouni K, Quelle FW, Sigmund CD.

Hypertension. 2017 Jul;70(1):174-182. doi: 10.1161/HYPERTENSIONAHA.117.09276. Epub 2017 May 15.

6.

Retinol-binding protein 7 is an endothelium-specific PPARγ cofactor mediating an antioxidant response through adiponectin.

Hu C, Keen HL, Lu KT, Liu X, Wu J, Davis DR, Ibeawuchi SC, Vogel S, Quelle FW, Sigmund CD.

JCI Insight. 2017 Mar 23;2(6):e91738. doi: 10.1172/jci.insight.91738.

7.

Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism.

Agbor LN, Ibeawuchi SC, Hu C, Wu J, Davis DR, Keen HL, Quelle FW, Sigmund CD.

JCI Insight. 2016 Nov 17;1(19):e91015. doi: 10.1172/jci.insight.91015.

8.

Endothelial PPAR-γ provides vascular protection from IL-1β-induced oxidative stress.

Mukohda M, Stump M, Ketsawatsomkron P, Hu C, Quelle FW, Sigmund CD.

Am J Physiol Heart Circ Physiol. 2016 Jan 1;310(1):H39-48. doi: 10.1152/ajpheart.00490.2015. Epub 2015 Nov 13.

9.

Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors.

Ibeawuchi SR, Agbor LN, Quelle FW, Sigmund CD.

J Biol Chem. 2015 Jul 31;290(31):19208-17. doi: 10.1074/jbc.M115.645358. Epub 2015 Jun 22.

10.

RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner.

Hagen J, Muniz VP, Falls KC, Reed SM, Taghiyev AF, Quelle FW, Gourronc FA, Klingelhutz AJ, Major HJ, Askeland RW, Sherman SK, O'Dorisio TM, Bellizzi AM, Howe JR, Darbro BW, Quelle DE.

Cancer Res. 2014 Nov 15;74(22):6661-70. doi: 10.1158/0008-5472.CAN-13-3742. Epub 2014 Oct 1.

11.

ARF sees Pdgfrβ through the miR.

Reed SM, Quelle FW, Quelle DE.

Cell Cycle. 2014;13(10):1520-1. doi: 10.4161/cc.28900. Epub 2014 Apr 22. No abstract available.

12.

Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53.

Reed SM, Hagen J, Tompkins VS, Thies K, Quelle FW, Quelle DE.

Cell Cycle. 2014;13(8):1288-98. doi: 10.4161/cc.28202. Epub 2014 Feb 19.

13.

PPARγ: no SirT, no service.

Quelle FW, Sigmund CD.

Circ Res. 2013 Feb 1;112(3):411-4. doi: 10.1161/CIRCRESAHA.113.300870. No abstract available.

14.

FOXO transcription factors enforce cell cycle checkpoints and promote survival of hematopoietic cells after DNA damage.

Lei H, Quelle FW.

Mol Cancer Res. 2009 Aug;7(8):1294-303. doi: 10.1158/1541-7786.MCR-08-0531. Epub 2009 Aug 11.

15.
16.

Cytokine signaling to the cell cycle.

Quelle FW.

Immunol Res. 2007;39(1-3):173-84. Review.

PMID:
17917064
17.

Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function.

Korgaonkar C, Hagen J, Tompkins V, Frazier AA, Allamargot C, Quelle FW, Quelle DE.

Mol Cell Biol. 2005 Feb;25(4):1258-71.

19.

Cytokine-induced phosphoinositide 3-kinase activity promotes Cdk2 activation in factor-dependent hematopoietic cells.

Henry MK, Nimbalkar D, Hohl RJ, Quelle FW.

Exp Cell Res. 2004 Sep 10;299(1):257-66.

PMID:
15302592
20.

Erythropoietin receptors associate with a ubiquitin ligase, p33RUL, and require its activity for erythropoietin-induced proliferation.

Friedman AD, Nimbalkar D, Quelle FW.

J Biol Chem. 2003 Jul 18;278(29):26851-61. Epub 2003 May 13.

21.
23.
24.

Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways.

Quelle FW, Wang J, Feng J, Wang D, Cleveland JL, Ihle JN, Zambetti GP.

Genes Dev. 1998 Apr 15;12(8):1099-107.

25.

Jaks and Stats in cytokine signaling.

Ihle JN, Nosaka T, Thierfelder W, Quelle FW, Shimoda K.

Stem Cells. 1997;15 Suppl 1:105-11; discussion 112. Review.

26.

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene.

Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DA, Doherty PC, Grosveld G, Paul WE, Ihle JN.

Nature. 1996 Apr 18;380(6575):630-3.

PMID:
8602264
27.

Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.

Quelle FW, Wang D, Nosaka T, Thierfelder WE, Stravopodis D, Weinstein Y, Ihle JN.

Mol Cell Biol. 1996 Apr;16(4):1622-31.

28.

Distribution of the mammalian Stat gene family in mouse chromosomes.

Copeland NG, Gilbert DJ, Schindler C, Zhong Z, Wen Z, Darnell JE Jr, Mui AL, Miyajima A, Quelle FW, Ihle JN, et al.

Genomics. 1995 Sep 1;29(1):225-8.

PMID:
8530075
29.
30.

Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases.

Yin T, Keller SR, Quelle FW, Witthuhn BA, Tsang ML, Lienhard GE, Ihle JN, Yang YC.

J Biol Chem. 1995 Sep 1;270(35):20497-502.

31.

Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.

Quelle FW, Shimoda K, Thierfelder W, Fischer C, Kim A, Ruben SM, Cleveland JL, Pierce JH, Keegan AD, Nelms K, et al.

Mol Cell Biol. 1995 Jun;15(6):3336-43.

32.

Signaling through the hematopoietic cytokine receptors.

Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Silvennoinen O.

Annu Rev Immunol. 1995;13:369-98. Review.

PMID:
7612228
33.

Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor.

Miura O, Miura Y, Nakamura N, Quelle FW, Witthuhn BA, Ihle JN, Aoki N.

Blood. 1994 Dec 15;84(12):4135-41.

PMID:
7527668
34.

Erythropoietin induces association of the JAK2 protein tyrosine kinase with the erythropoietin receptor in vivo.

Miura O, Nakamura N, Quelle FW, Witthuhn BA, Ihle JN, Aoki N.

Blood. 1994 Sep 1;84(5):1501-7.

PMID:
8068943
35.

Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation.

Yamamoto K, Quelle FW, Thierfelder WE, Kreider BL, Gilbert DJ, Jenkins NA, Copeland NG, Silvennoinen O, Ihle JN.

Mol Cell Biol. 1994 Jul;14(7):4342-9.

36.

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region.

Quelle FW, Sato N, Witthuhn BA, Inhorn RC, Eder M, Miyajima A, Griffin JD, Ihle JN.

Mol Cell Biol. 1994 Jul;14(7):4335-41.

37.

Signaling by the cytokine receptor superfamily: JAKs and STATs.

Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O.

Trends Biochem Sci. 1994 May;19(5):222-7. Review.

PMID:
8048164
38.

Cytokine receptors and signal transduction.

Ihle JN, Witthuhn B, Tang B, Yi T, Quelle FW.

Baillieres Clin Haematol. 1994 Mar;7(1):17-48. Review.

PMID:
7518712
39.

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.

Stahl N, Boulton TG, Farruggella T, Ip NY, Davis S, Witthuhn BA, Quelle FW, Silvennoinen O, Barbieri G, Pellegrini S, et al.

Science. 1994 Jan 7;263(5143):92-5.

PMID:
8272873
40.

Protein tyrosine phosphorylation in the regulation of hematopoiesis by receptors of the cytokine-receptor superfamily.

Ihle JN, Witthuhn BA, Quelle FW, Silvennoinen O, Tang B, Yi T.

Blood Cells. 1994;20(1):65-80; discussion 80-2. Review.

PMID:
7994062
41.

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway.

Watling D, Guschin D, Müller M, Silvennoinen O, Witthuhn BA, Quelle FW, Rogers NC, Schindler C, Stark GR, Ihle JN, et al.

Nature. 1993 Nov 11;366(6451):166-70.

PMID:
7901766
42.

Signal transduction through the receptor for erythropoietin.

Ihle JN, Quelle FW, Miura O.

Semin Immunol. 1993 Oct;5(5):375-89. Review.

PMID:
8260653
43.

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

Silvennoinen O, Witthuhn BA, Quelle FW, Cleveland JL, Yi T, Ihle JN.

Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8429-33.

44.

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin.

Witthuhn BA, Quelle FW, Silvennoinen O, Yi T, Tang B, Miura O, Ihle JN.

Cell. 1993 Jul 30;74(2):227-36.

PMID:
8343951
45.

Cytokine-induced phosphorylation of pp100 in FDC-ER cells is at tyrosine residues.

Quelle FW, Egerton M, Samelson LE, Wojchowski DM.

Biochem Biophys Res Commun. 1992 Nov 16;188(3):1040-6.

PMID:
1280128
49.

High-level expression and purification of a recombinant human erythropoietin produced using a baculovirus vector.

Quelle FW, Caslake LF, Burkert RE, Wojchowski DM.

Blood. 1989 Aug 1;74(2):652-7.

PMID:
2752139
50.

[3H]dexamethasone binding to plasma membrane-enriched fractions from liver of nonadrenalectomized rats.

Quelle FW, Smith RV, Hrycyna CA, Kaliban TD, Crooks JA, O'Brien JM.

Endocrinology. 1988 Sep;123(3):1642-51.

PMID:
2841103

Supplemental Content

Loading ...
Support Center