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Items: 1 to 50 of 103

1.

Use of Multilayer Stent and Fenestrated Endograft in a Single Session to Treat Long-Segment Aorta.

Pua U, Tan GWL, Kolvenbach RR, Quek LHH.

Ann Vasc Surg. 2019 Aug 5. pii: S0890-5096(19)30537-0. doi: 10.1016/j.avsg.2019.05.042. [Epub ahead of print]

PMID:
31394240
2.

Salvage of exhausted neck access using a novel inside-out device in dialysis-dependent patients.

Quek LHH, Tan TSM, Tan GWL, Pua U.

Hemodial Int. 2019 Jul 22. doi: 10.1111/hdi.12770. [Epub ahead of print]

PMID:
31330075
3.

Myocardial substrate changes in advanced ischaemic and advanced dilated human heart failure.

Cao J, Koay YC, Quek LE, Parker B, Lal S, O'Sullivan JF.

Eur J Heart Fail. 2019 Aug;21(8):1042-1045. doi: 10.1002/ejhf.1479. Epub 2019 Jun 11. No abstract available.

PMID:
31184404
4.

Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells.

Liu M, Hancock SE, Sultani G, Wilkins BP, Ding E, Osborne B, Quek LE, Turner N.

J Clin Med. 2019 Jun 8;8(6). pii: E822. doi: 10.3390/jcm8060822.

5.

Nicotinamide Metabolism Modulates the Proliferation/Differentiation Balance and Senescence of Human Primary Keratinocytes.

Tan CL, Chin T, Tan CYR, Rovito HA, Quek LS, Oblong JE, Bellanger S.

J Invest Dermatol. 2019 Aug;139(8):1638-1647.e3. doi: 10.1016/j.jid.2019.02.005. Epub 2019 Feb 15.

6.

Using the Human Genome-Scale Metabolic Model Recon 2 for Steady-State Flux Analysis of Cancer Cell Metabolism.

Quek LE, Turner N.

Methods Mol Biol. 2019;1928:479-489. doi: 10.1007/978-1-4939-9027-6_25.

PMID:
30725471
7.

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.

Haase D, Stevenson KE, Neuberg D, Maciejewski JP, Nazha A, Sekeres MA, Ebert BL, Garcia-Manero G, Haferlach C, Haferlach T, Kern W, Ogawa S, Nagata Y, Yoshida K, Graubert TA, Walter MJ, List AF, Komrokji RS, Padron E, Sallman D, Papaemmanuil E, Campbell PJ, Savona MR, Seegmiller A, Adès L, Fenaux P, Shih LY, Bowen D, Groves MJ, Tauro S, Fontenay M, Kosmider O, Bar-Natan M, Steensma D, Stone R, Heuser M, Thol F, Cazzola M, Malcovati L, Karsan A, Ganster C, Hellström-Lindberg E, Boultwood J, Pellagatti A, Santini V, Quek L, Vyas P, Tüchler H, Greenberg PL, Bejar R; International Working Group for MDS Molecular Prognostic Committee.

Leukemia. 2019 Jul;33(7):1747-1758. doi: 10.1038/s41375-018-0351-2. Epub 2019 Jan 11.

8.

Feasibility Study of "Snuffbox" Radial Access for Visceral Interventions.

Pua U, Sim JZT, Quek LHH, Kwan J, Lim GHT, Huang IKH.

J Vasc Interv Radiol. 2018 Sep;29(9):1276-1280. doi: 10.1016/j.jvir.2018.05.002.

PMID:
30146194
9.

Protein hypoacylation induced by Sirt5 overexpression has minimal metabolic effect in mice.

Bentley NL, Fiveash CE, Osborne B, Quek LE, Ogura M, Inagaki N, Cooney GJ, Polly P, Montgomery MK, Turner N.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1349-1355. doi: 10.1016/j.bbrc.2018.07.047. Epub 2018 Jul 13.

PMID:
30017194
10.

Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib.

Quek L, David MD, Kennedy A, Metzner M, Amatangelo M, Shih A, Stoilova B, Quivoron C, Heiblig M, Willekens C, Saada V, Alsafadi S, Vijayabaskar MS, Peniket A, Bernard OA, Agresta S, Yen K, MacBeth K, Stein E, Vassiliou GS, Levine R, De Botton S, Thakurta A, Penard-Lacronique V, Vyas P.

Nat Med. 2018 Aug;24(8):1167-1177. doi: 10.1038/s41591-018-0115-6. Epub 2018 Jul 16.

PMID:
30013198
11.

Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways.

van Geldermalsen M, Quek LE, Turner N, Freidman N, Pang A, Guan YF, Krycer JR, Ryan R, Wang Q, Holst J.

BMC Cancer. 2018 Jun 26;18(1):689. doi: 10.1186/s12885-018-4599-8.

12.

From reconstruction to C4 metabolic engineering: A case study for overproduction of polyhydroxybutyrate in bioenergy grasses.

Gomes de Oliveira Dal'Molin C, Quek LE, Saa PA, Palfreyman R, Nielsen LK.

Plant Sci. 2018 Aug;273:50-60. doi: 10.1016/j.plantsci.2018.03.027. Epub 2018 Apr 5.

PMID:
29907309
13.

Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect.

Buchsteiner M, Quek LE, Gray P, Nielsen LK.

Biotechnol Bioeng. 2018 Sep;115(9):2315-2327. doi: 10.1002/bit.26724. Epub 2018 May 22.

PMID:
29704441
14.

Safety and Efficacy of Percutaneous Thermal Ablation of Juxta-Cardiac Hepatic Tumours.

Kwan J, Appuhamy C, Lim GHT, Huang IKH, Quek L, Pua U.

Cardiovasc Intervent Radiol. 2018 Jun;41(6):920-927. doi: 10.1007/s00270-018-1938-8. Epub 2018 Mar 26.

PMID:
29582128
15.

Dual Role of the Anaphase Promoting Complex/Cyclosome in Regulating Stemness and Differentiation in Human Primary Keratinocytes.

Quek LS, Grasset N, Jasmen JB, Robinson KS, Bellanger S.

J Invest Dermatol. 2018 Aug;138(8):1851-1861. doi: 10.1016/j.jid.2018.02.033. Epub 2018 Mar 9.

16.

Fructose bisphosphatase 2 overexpression increases glucose uptake in skeletal muscle.

Bakshi I, Suryana E, Small L, Quek LE, Brandon AE, Turner N, Cooney GJ.

J Endocrinol. 2018 May;237(2):101-111. doi: 10.1530/JOE-17-0555. Epub 2018 Mar 5.

PMID:
29507044
17.

Diabetic Foot Limb Salvage-A Series of 809 Attempts and Predictors for Endovascular Limb Salvage Failure.

Lo ZJ, Lin Z, Pua U, Quek LHH, Tan BP, Punamiya S, Tan GWL, Narayanan S, Chandrasekar S.

Ann Vasc Surg. 2018 May;49:9-16. doi: 10.1016/j.avsg.2018.01.061. Epub 2018 Feb 9.

PMID:
29428535
18.

Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake.

Small L, Brandon AE, Quek LE, Krycer JR, James DE, Turner N, Cooney GJ.

Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E258-E266. doi: 10.1152/ajpendo.00386.2017. Epub 2018 Feb 6.

19.

Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia.

Quek L, Ferguson P, Metzner M, Ahmed I, Kennedy A, Garnett C, Jeffries S, Walter C, Piechocki K, Timbs A, Danby R, Raghavan M, Peniket A, Griffiths M, Bacon A, Ward J, Wheatley K, Vyas P, Craddock C.

Blood Adv. 2016 Dec 14;1(3):193-204. doi: 10.1182/bloodadvances.2016000760. eCollection 2016 Dec 27.

20.

Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism.

Krycer JR, Yugi K, Hirayama A, Fazakerley DJ, Quek LE, Scalzo R, Ohno S, Hodson MP, Ikeda S, Shoji F, Suzuki K, Domanova W, Parker BL, Nelson ME, Humphrey SJ, Turner N, Hoehn KL, Cooney GJ, Soga T, Kuroda S, James DE.

Cell Rep. 2017 Dec 19;21(12):3536-3547. doi: 10.1016/j.celrep.2017.11.085.

21.

"Snuffbox" Distal Radial Access.

Pua U, Quek LHH.

J Vasc Interv Radiol. 2018 Jan;29(1):44. doi: 10.1016/j.jvir.2017.07.011. No abstract available.

PMID:
29258662
22.

Early Experience and Lessons Learnt with Customized Fenestrated Thoracic Endovascular Aortic Reconstruction for Aortic Arch Pathology in an Asian Population.

Tan GWL, Quek L, Tan BP, Pua U.

Cardiovasc Intervent Radiol. 2018 Apr;41(4):544-553. doi: 10.1007/s00270-017-1858-z. Epub 2017 Dec 13.

PMID:
29238868
23.

Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells.

Karamitros D, Stoilova B, Aboukhalil Z, Hamey F, Reinisch A, Samitsch M, Quek L, Otto G, Repapi E, Doondeea J, Usukhbayar B, Calvo J, Taylor S, Goardon N, Six E, Pflumio F, Porcher C, Majeti R, Göttgens B, Vyas P.

Nat Immunol. 2018 Jan;19(1):85-97. doi: 10.1038/s41590-017-0001-2. Epub 2017 Nov 21.

24.

Efficacy and outcomes of a mobile app targeting alcohol use in young people.

Hides L, Quinn C, Cockshaw W, Stoyanov S, Zelenko O, Johnson D, Tjondronegoro D, Quek LH, Kavanagh DJ.

Addict Behav. 2018 Feb;77:89-95. doi: 10.1016/j.addbeh.2017.09.020. Epub 2017 Sep 29.

PMID:
28992580
25.

Cone-beam CT acquisition during transradial TACE made easy; use of the swivel arm board.

Pua U, Teo CC, U PT, Quek LHH.

Br J Radiol. 2018 Jan;91(1081):20170248. doi: 10.1259/bjr.20170248. Epub 2017 Oct 26.

26.

Effectiveness of a post-emergency department discharge multidisciplinary bundle in reducing acute hospital admissions for the elderly.

Ong CEC, Asinas-Tan M, Quek LS, de Dios M, Cai XT, Lim BL.

Eur J Emerg Med. 2019 Apr;26(2):94-99. doi: 10.1097/MEJ.0000000000000504.

PMID:
28906260
27.

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.

Mettananda S, Fisher CA, Hay D, Badat M, Quek L, Clark K, Hublitz P, Downes D, Kerry J, Gosden M, Telenius J, Sloane-Stanley JA, Faustino P, Coelho A, Doondeea J, Usukhbayar B, Sopp P, Sharpe JA, Hughes JR, Vyas P, Gibbons RJ, Higgs DR.

Nat Commun. 2017 Sep 4;8(1):424. doi: 10.1038/s41467-017-00479-7.

28.

Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature.

Craddock CF, Houlton AE, Quek LS, Ferguson P, Gbandi E, Roberts C, Metzner M, Garcia-Martin N, Kennedy A, Hamblin A, Raghavan M, Nagra S, Dudley L, Wheatley K, McMullin MF, Pillai SP, Kelly RJ, Siddique S, Dennis M, Cavenagh JD, Vyas P.

Clin Cancer Res. 2017 Nov 1;23(21):6430-6440. doi: 10.1158/1078-0432.CCR-17-1423. Epub 2017 Aug 1.

29.

Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response.

Amatangelo MD, Quek L, Shih A, Stein EM, Roshal M, David MD, Marteyn B, Farnoud NR, de Botton S, Bernard OA, Wu B, Yen KE, Tallman MS, Papaemmanuil E, Penard-Lacronique V, Thakurta A, Vyas P, Levine RL.

Blood. 2017 Aug 10;130(6):732-741. doi: 10.1182/blood-2017-04-779447. Epub 2017 Jun 6.

30.

Accentuation of Insufficient Landing Zone Using High-volume Three-dimensional Coils during Iliac Aneurysm Stent Grafting for Hypogastric Artery Preservation.

Pua U, Quek LHH, Tan GWL.

Ann Vasc Surg. 2017 Aug;43:315.e13-315.e16. doi: 10.1016/j.avsg.2017.03.191. Epub 2017 May 4.

PMID:
28479430
31.

Bubble Trouble: Air Embolism during Multiple EndoAnchor Application.

Pua U, Tan GWL, Quek LHH.

J Vasc Interv Radiol. 2017 May;28(5):768-770. doi: 10.1016/j.jvir.2016.12.1211. No abstract available.

PMID:
28431655
32.

A Question Mark on Thoracoabdominal Aneurysm.

Pua U, Tan GWL, Quek LHH.

J Vasc Interv Radiol. 2017 May;28(5):655. doi: 10.1016/j.jvir.2016.12.1225. No abstract available.

PMID:
28431646
33.

Identifying the optimum source of mesenchymal stem cells for use in knee surgery.

Davies BM, Snelling SJB, Quek L, Hakimi O, Ye H, Carr A, Price AJ.

J Orthop Res. 2017 Sep;35(9):1868-1875. doi: 10.1002/jor.23501. Epub 2017 Mar 2.

34.

A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.

Hefzi H, Ang KS, Hanscho M, Bordbar A, Ruckerbauer D, Lakshmanan M, Orellana CA, Baycin-Hizal D, Huang Y, Ley D, Martinez VS, Kyriakopoulos S, Jiménez NE, Zielinski DC, Quek LE, Wulff T, Arnsdorf J, Li S, Lee JS, Paglia G, Loira N, Spahn PN, Pedersen LE, Gutierrez JM, King ZA, Lund AM, Nagarajan H, Thomas A, Abdel-Haleem AM, Zanghellini J, Kildegaard HF, Voldborg BG, Gerdtzen ZP, Betenbaugh MJ, Palsson BO, Andersen MR, Nielsen LK, Borth N, Lee DY, Lewis NE.

Cell Syst. 2016 Nov 23;3(5):434-443.e8. doi: 10.1016/j.cels.2016.10.020.

35.
36.

Fast exchange fluxes around the pyruvate node: a leaky cell model to explain the gain and loss of unlabelled and labelled metabolites in a tracer experiment.

Quek LE, Liu M, Joshi S, Turner N.

Cancer Metab. 2016 Jul 4;4:13. doi: 10.1186/s40170-016-0153-9. eCollection 2016.

37.

Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

Quek L, Otto GW, Garnett C, Lhermitte L, Karamitros D, Stoilova B, Lau IJ, Doondeea J, Usukhbayar B, Kennedy A, Metzner M, Goardon N, Ivey A, Allen C, Gale R, Davies B, Sternberg A, Killick S, Hunter H, Cahalin P, Price A, Carr A, Griffiths M, Virgo P, Mackinnon S, Grimwade D, Freeman S, Russell N, Craddock C, Mead A, Peniket A, Porcher C, Vyas P.

J Exp Med. 2016 Jul 25;213(8):1513-35. doi: 10.1084/jem.20151775. Epub 2016 Jul 4.

38.

Recon 2.2: from reconstruction to model of human metabolism.

Swainston N, Smallbone K, Hefzi H, Dobson PD, Brewer J, Hanscho M, Zielinski DC, Ang KS, Gardiner NJ, Gutierrez JM, Kyriakopoulos S, Lakshmanan M, Li S, Liu JK, Martínez VS, Orellana CA, Quek LE, Thomas A, Zanghellini J, Borth N, Lee DY, Nielsen LK, Kell DB, Lewis NE, Mendes P.

Metabolomics. 2016;12:109. Epub 2016 Jun 7.

39.

Transvenous Salvage of Migrated Large Volume Detachable Coil.

Pua U, Quek LH, Tan GW.

Cardiovasc Intervent Radiol. 2016 Dec;39(12):1797-1800. Epub 2016 Jun 6. No abstract available.

PMID:
27272710
40.

Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease.

Couttas TA, Kain N, Suchowerska AK, Quek LE, Turner N, Fath T, Garner B, Don AS.

Neurobiol Aging. 2016 Jul;43:89-100. doi: 10.1016/j.neurobiolaging.2016.03.027. Epub 2016 Apr 4.

PMID:
27255818
41.

Single-Session Multilevel "Central Stentoplasty".

Pua U, Quek LH, Lim GH, Nolan CP.

J Vasc Interv Radiol. 2016 Mar;27(3):416-7. doi: 10.1016/j.jvir.2015.10.018. No abstract available.

PMID:
26916940
42.

Use of Suture-Mediated Closure Device in Percutaneous Direct Carotid Puncture During Chimney-Thoracic Endovascular Aortic Repair.

Chan G, Quek LH, Tan GL, Pua U.

Cardiovasc Intervent Radiol. 2016 Jul;39(7):1036-9. doi: 10.1007/s00270-016-1294-5. Epub 2016 Jan 13.

PMID:
26762633
43.

Delayed Recurrence of Type 1A Endoleak with Aortic Rupture and Hemorrhage After Endovascular Aneurysm Sealing (EVAS).

Pua U, Quek LH, Tan GW.

Cardiovasc Intervent Radiol. 2016 Jul;39(7):1061-5. doi: 10.1007/s00270-015-1291-0. Epub 2016 Jan 12. No abstract available.

PMID:
26757910
44.

Covered endovascular reconstruction of aortic bifurcation technique in infected aortic aneurysm.

Pua U, Quek LH, Tan GW.

J Vasc Interv Radiol. 2015 Jul;26(7):1079-82. doi: 10.1016/j.jvir.2015.02.003. No abstract available.

PMID:
26095274
45.

Inferior Mesenteric Artery Rendezvous for Revascularization of Aorto-iliac Occlusive Disease.

Pua U, Quek LH, Tan GW.

Cardiovasc Intervent Radiol. 2015 Dec;38(6):1670-3. doi: 10.1007/s00270-015-1150-z. Epub 2015 Jun 6. No abstract available.

PMID:
26048017
46.

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.

Taylor JC, Martin HC, Lise S, Broxholme J, Cazier JB, Rimmer A, Kanapin A, Lunter G, Fiddy S, Allan C, Aricescu AR, Attar M, Babbs C, Becq J, Beeson D, Bento C, Bignell P, Blair E, Buckle VJ, Bull K, Cais O, Cario H, Chapel H, Copley RR, Cornall R, Craft J, Dahan K, Davenport EE, Dendrou C, Devuyst O, Fenwick AL, Flint J, Fugger L, Gilbert RD, Goriely A, Green A, Greger IH, Grocock R, Gruszczyk AV, Hastings R, Hatton E, Higgs D, Hill A, Holmes C, Howard M, Hughes L, Humburg P, Johnson D, Karpe F, Kingsbury Z, Kini U, Knight JC, Krohn J, Lamble S, Langman C, Lonie L, Luck J, McCarthy D, McGowan SJ, McMullin MF, Miller KA, Murray L, Németh AH, Nesbit MA, Nutt D, Ormondroyd E, Oturai AB, Pagnamenta A, Patel SY, Percy M, Petousi N, Piazza P, Piret SE, Polanco-Echeverry G, Popitsch N, Powrie F, Pugh C, Quek L, Robbins PA, Robson K, Russo A, Sahgal N, van Schouwenburg PA, Schuh A, Silverman E, Simmons A, Sørensen PS, Sweeney E, Taylor J, Thakker RV, Tomlinson I, Trebes A, Twigg SR, Uhlig HH, Vyas P, Vyse T, Wall SA, Watkins H, Whyte MP, Witty L, Wright B, Yau C, Buck D, Humphray S, Ratcliffe PJ, Bell JI, Wilkie AO, Bentley D, Donnelly P, McVean G.

Nat Genet. 2015 Jul;47(7):717-726. doi: 10.1038/ng.3304. Epub 2015 May 18.

47.

Stranglehold on the spindle assembly checkpoint: the human papillomavirus E2 protein provokes BUBR1-dependent aneuploidy.

Tan CL, Teissier S, Gunaratne J, Quek LS, Bellanger S.

Cell Cycle. 2015;14(9):1459-70. doi: 10.1080/15384101.2015.1021519.

48.

A multi-tissue genome-scale metabolic modeling framework for the analysis of whole plant systems.

Gomes de Oliveira Dal'Molin C, Quek LE, Saa PA, Nielsen LK.

Front Plant Sci. 2015 Jan 22;6:4. doi: 10.3389/fpls.2015.00004. eCollection 2015.

49.

Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrations.

Turner J, Quek LE, Titmarsh D, Krömer JO, Kao LP, Nielsen L, Wolvetang E, Cooper-White J.

PLoS One. 2014 Nov 20;9(11):e112757. doi: 10.1371/journal.pone.0112757. eCollection 2014.

50.

Formula one night race in Singapore: a 4-year analysis of a planned mass gathering.

Ho WH, Koenig KL, Quek LS.

Prehosp Disaster Med. 2014 Oct;29(5):489-93. doi: 10.1017/S1049023X14000971. Epub 2014 Sep 16.

PMID:
25226216

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