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Physiologic response to chronic house dust mite exposure in mice is dependent on lot characteristics.

Cyphert-Daly JM, Yang Z, Ingram JL, Tighe RM, Que LG.

J Allergy Clin Immunol. 2019 Jul 29. pii: S0091-6749(19)30968-6. doi: 10.1016/j.jaci.2019.07.019. [Epub ahead of print] No abstract available.


Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.

Dy ABC, Arif MZ, Addison KJ, Que LG, Boitano S, Kraft M, Ledford JG.

J Immunol. 2019 Sep 1;203(5):1122-1130. doi: 10.4049/jimmunol.1900546. Epub 2019 Jul 26.


Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis.

Chen P, Wang S, Janardhan KS, Zemans RL, Deng W, Karmaus P, Shen S, Sunday M, Que LG, Fessler MB, Zhong XP.

J Immunol. 2019 Sep 1;203(5):1208-1217. doi: 10.4049/jimmunol.1900566. Epub 2019 Jul 17.


Control of antiviral innate immune response by protein geranylgeranylation.

Yang S, Harding AT, Sweeney C, Miao D, Swan G, Zhou C, Jiang Z, Fitzgerald KA, Hammer G, Bergo MO, Kroh HK, Lacy DB, Sun C, Glogauer M, Que LG, Heaton NS, Wang D.

Sci Adv. 2019 May 29;5(5):eaav7999. doi: 10.1126/sciadv.aav7999. eCollection 2019 May.


Identifying an at-risk population for poor asthma outcomes: Data from the American Lung Association Asthma Clinical Trials Registry.

Bose S, Henderson RJ, Rogers L, Casale T, Skloot G, Soler X, Wise RA, Que LG.

J Allergy Clin Immunol Pract. 2019 Apr 28. pii: S2213-2198(19)30397-6. doi: 10.1016/j.jaip.2019.04.024. [Epub ahead of print] No abstract available.


Sex Modifies Acute Ozone-Mediated Airway Physiologic Responses.

Birukova A, Cyphert-Daly J, Cumming RI, Yu YR, Gowdy KM, Que LG, Tighe RM.

Toxicol Sci. 2019 Jun 1;169(2):499-510. doi: 10.1093/toxsci/kfz056.


A Systematic Review of Patient- and Family-Level Inhaled Corticosteroid Adherence Interventions in Black/African Americans.

Riley IL, Murphy B, Razouki Z, Krishnan JA, Apter A, Okelo S, Kraft M, Feltner C, Que LG, Boulware LE.

J Allergy Clin Immunol Pract. 2019 Apr;7(4):1184-1193.e3. doi: 10.1016/j.jaip.2018.10.036. Epub 2018 Nov 3.


Does Obesity Increase Respiratory Tract Infections in Patients with Asthma?

Tang M, Henderson RJ, Holbrook JT, Que LG, Mathews AM, Wise RA, Dixon AE, Peters SP, Rogers L, Smith LJ, Teague WG, Lang JE.

J Allergy Clin Immunol Pract. 2019 Mar;7(3):954-961.e6. doi: 10.1016/j.jaip.2018.09.033. Epub 2018 Oct 9.


Identification of a Novel Inhibitor of Human Rhinovirus Replication and Inflammation in Airway Epithelial Cells.

Yang Z, Bochkov YA, Voelker DR, Foster MW, Que LG.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):58-67. doi: 10.1165/rcmb.2018-0058OC.


Test Performance Characteristics of the AIR, GAD-7 and HADS-Anxiety Screening Questionnaires for Anxiety in Chronic Obstructive Pulmonary Disease.

Baker AM, Holbrook JT, Yohannes AM, Eakin MN, Sugar EA, Henderson RJ, Casper AS, Kaminsky DA, Rea AL, Mathews AM, Que LG, Ramsdell JW, Gerald LB, Wise RA, Hanania NA; for American Lung Association Airways Clinical Research Centers.

Ann Am Thorac Soc. 2018 Jul 9. doi: 10.1513/AnnalsATS.201708-631OC. [Epub ahead of print]


Effect of the S-nitrosoglutathione reductase inhibitor N6022 on bronchial hyperreactivity in asthma.

Que LG, Yang Z, Lugogo NL, Katial RK, Shoemaker SA, Troha JM, Rodman DM, Tighe RM, Kraft M.

Immun Inflamm Dis. 2018 Jun;6(2):322-331. doi: 10.1002/iid3.220. Epub 2018 Apr 11.


iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.

Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, Qiu Y, Que LG, Foster WM, Xia Z, Chi H, Zhong XP.

J Clin Invest. 2018 Apr 2;128(4):1707-1708. doi: 10.1172/JCI120531. Epub 2018 Mar 1. No abstract available.


Validation of spirometry prediction equations in western Kenya.

Paul DW, Lagat DK, MacIntyre N, Egger JR, Murdoch DM, Que LG, Kussin PS.

Int J Tuberc Lung Dis. 2018 Jan 1;22(1):112-118. doi: 10.5588/ijtld.17.0005.


Factors associated with reporting results for pulmonary clinical trials in

Riley IL, Boulware LE, Sun JL, Chiswell K, Que LG, Kraft M, Todd JL, Palmer SM, Anderson ML.

Clin Trials. 2018 Feb;15(1):87-94. doi: 10.1177/1740774517740352. Epub 2017 Nov 10.


iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.

Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, Qiu Y, Que LG, Foster WM, Xia Z, Chi H, Zhong XP.

J Clin Invest. 2017 Nov 1;127(11):4216. doi: 10.1172/JCI98066. Epub 2017 Nov 1. No abstract available.


Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity.

Suwanpradid J, Shih M, Pontius L, Yang B, Birukova A, Guttman-Yassky E, Corcoran DL, Que LG, Tighe RM, MacLeod AS.

J Immunol. 2017 Sep 1;199(5):1827-1834. doi: 10.4049/jimmunol.1700739. Epub 2017 Jul 26.


Development and validation of an electronic medical record (EMR)-based computed phenotype of HIV-1 infection.

Paul DW, Neely NB, Clement M, Riley I, Al-Hegelan M, Phelan M, Kraft M, Murdoch DM, Lucas J, Bartlett J, McKellar M, Que LG.

J Am Med Inform Assoc. 2018 Feb 1;25(2):150-157. doi: 10.1093/jamia/ocx061.


Correction to "Proteomic Characterization of the Cellular Response to Nitrosative Stress Mediated by S-Nitrosoglutathione Reductase Inhibition".

Foster MW, Yang Z, Gooden DM, Thompson JW, Ball CH, Turner ME, Hou Y, Pi J, Moseley MA, Que LG.

J Proteome Res. 2017 Jul 7;16(7):2661. doi: 10.1021/acs.jproteome.7b00368. Epub 2017 Jun 19. No abstract available.


Use and Perceived Risk of Electronic Cigarettes Among North Carolina Middle and High School Students.

Giovacchini CX, Pacek L, McClernon FJ, Que LG.

N C Med J. 2017 Jan-Feb;78(1):7-13. doi: 10.18043/ncm.78.1.7.


Using Hyperpolarized 129Xe MRI to Quantify the Pulmonary Ventilation Distribution.

He M, Driehuys B, Que LG, Huang YT.

Acad Radiol. 2016 Dec;23(12):1521-1531. doi: 10.1016/j.acra.2016.07.014. Epub 2016 Sep 9.


l-citrulline prevents asymmetric dimethylarginine-mediated reductions in nitric oxide and nitrosative stress in primary human airway epithelial cells.

Winnica D, Que LG, Baffi C, Grasemann H, Fiedler K, Yang Z, Etling E, Wasil K, Wenzel SE, Freeman B, Holguin F.

Clin Exp Allergy. 2017 Feb;47(2):190-199. doi: 10.1111/cea.12802. Epub 2016 Oct 4.


Genetic Variation in Surfactant Protein-A2 Results in Altered Regulation of Eosinophil Activities and Enhanced Eosinophilia in Patients with Asthma.

Ledford JG, Addison KJ, Francisco D, Foster MW, Voelker DR, Que LG, Kraft M.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S101. doi: 10.1513/AnnalsATS.201508-520MG. No abstract available.


Metabolic Syndrome and the Lung.

Baffi CW, Wood L, Winnica D, Strollo PJ Jr, Gladwin MT, Que LG, Holguin F.

Chest. 2016 Jun;149(6):1525-34. doi: 10.1016/j.chest.2015.12.034. Epub 2016 Jan 20. Review.


Eosinophil-associated lung diseases. A cry for surfactant proteins A and D help?

Ledford JG, Addison KJ, Foster MW, Que LG.

Am J Respir Cell Mol Biol. 2014 Nov;51(5):604-14. doi: 10.1165/rcmb.2014-0095TR. Review.


Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial.

Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, Avila P, Bacharier LB, Bleecker E, Boushey HA, Chmiel J, Fitzpatrick AM, Gentile D, Hundal M, Israel E, Kraft M, Krishnan JA, LaForce C, Lazarus SC, Lemanske R, Lugogo N, Martin RJ, Mauger DT, Naureckas E, Peters SP, Phipatanakul W, Que LG, Sheshadri A, Smith L, Solway J, Sullivan-Vedder L, Sumino K, Wechsler ME, Wenzel S, White SR, Sutherland ER; National Heart, Lung, and Blood Institute’s AsthmaNet.

JAMA. 2014 May;311(20):2083-91. doi: 10.1001/jama.2014.5052.


iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.

Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, Qiu Y, Que LG, Foster WM, Xia Z, Chi H, Zhong XP.

J Clin Invest. 2014 Apr;124(4):1685-98. doi: 10.1172/JCI69780. Epub 2014 Mar 10. Erratum in: J Clin Invest. 2018 Apr 2;128(4):1707-1708.


High intensive care unit admission rate for 2013-2014 influenza is associated with a low rate of vaccination.

Catania J, Que LG, Govert JA, Hollingsworth JW, Wolfe CR.

Am J Respir Crit Care Med. 2014 Feb 15;189(4):485-7. doi: 10.1164/rccm.201401-0066LE. No abstract available.


Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure.

Foster MW, Thompson JW, Que LG, Yang IV, Schwartz DA, Moseley MA, Marshall HE.

J Proteome Res. 2013 May 3;12(5):2194-205. doi: 10.1021/pr400066g. Epub 2013 Apr 24.


Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype.

Lugogo NL, Hollingsworth JW, Howell DL, Que LG, Francisco D, Church TD, Potts-Kant EN, Ingram JL, Wang Y, Jung SH, Kraft M.

Am J Respir Crit Care Med. 2012 Sep 1;186(5):404-11. doi: 10.1164/rccm.201109-1671OC. Epub 2012 Jul 5. Retraction in: Am J Respir Crit Care Med. 2015 Jul 15;192(2):264.


Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition.

Foster MW, Yang Z, Gooden DM, Thompson JW, Ball CH, Turner ME, Hou Y, Pi J, Moseley MA, Que LG.

J Proteome Res. 2012 Apr 6;11(4):2480-91. doi: 10.1021/pr201180m. Epub 2012 Mar 19. Erratum in: J Proteome Res. 2017 Jul 7;16(7):2661.


SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells.

Wang Y, Zhu Z, Church TD, Lugogo NL, Que LG, Francisco D, Ingram JL, Huggins M, Beaver DM, Wright JR, Kraft M.

J Immunol. 2012 Apr 1;188(7):3371-81. doi: 10.4049/jimmunol.1100573. Epub 2012 Feb 27.


Increased Nitric Oxide Production Prevents Airway Hyperresponsiveness in Caveolin-1 Deficient Mice Following Endotoxin Exposure.

Hsia BJ, Pastva AM, Giamberardino CD, Potts-Kant EN, Foster WM, Que LG, Abraham SN, Wright JR, Zaas DW.

J Allergy Ther. 2012 Jan 25;Suppl 1(4). pii: 2155-.


The clinical and environmental determinants of airway transcriptional profiles in allergic asthma.

Yang IV, Tomfohr J, Singh J, Foss CM, Marshall HE, Que LG, McElvania-Tekippe E, Florence S, Sundy JS, Schwartz DA.

Am J Respir Crit Care Med. 2012 Mar 15;185(6):620-7. doi: 10.1164/rccm.201108-1503OC. Epub 2012 Jan 12.


Biochemistry of asthma.

Que LG, Janssen-Heininger Y.

Biochim Biophys Acta. 2011 Nov;1810(11):1007. doi: 10.1016/j.bbagen.2011.08.013. No abstract available.


S-nitrosoglutathione supplementation to ovalbumin-sensitized and -challenged mice ameliorates methacholine-induced bronchoconstriction.

Foster MW, Yang Z, Potts EN, Michael Foster W, Que LG.

Am J Physiol Lung Cell Mol Physiol. 2011 Nov;301(5):L739-44. doi: 10.1152/ajplung.00134.2011. Epub 2011 Jul 22. Retraction in: Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308(9):L981.


Pulmonary function, bronchial reactivity, and epithelial permeability are response phenotypes to ozone and develop differentially in healthy humans.

Que LG, Stiles JV, Sundy JS, Foster WM.

J Appl Physiol (1985). 2011 Sep;111(3):679-87. doi: 10.1152/japplphysiol.00337.2011. Epub 2011 Jun 23.


Rescue therapy in adult and pediatric patients with pH1N1 influenza infection: a tertiary center intensive care unit experience from April to October 2009.

Norfolk SG, Hollingsworth CL, Wolfe CR, Govert JA, Que LG, Cheifetz IM, Hollingsworth JW.

Crit Care Med. 2010 Nov;38(11):2103-7. doi: 10.1097/CCM.0b013e3181f268f1.


Gene expression profile in circulating mononuclear cells after exposure to ultrafine carbon particles.

Huang YC, Schmitt M, Yang Z, Que LG, Stewart JC, Frampton MW, Devlin RB.

Inhal Toxicol. 2010 Aug;22(10):835-46. doi: 10.3109/08958378.2010.486419.


GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol.

Choudhry S, Que LG, Yang Z, Liu L, Eng C, Kim SO, Kumar G, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Stamler JS, Burchard EG.

Pharmacogenet Genomics. 2010 Jun;20(6):351-8. doi: 10.1097/FPC.0b013e328337f992.


A prospective multicenter study of competency metrics and educational interventions in the learning of bronchoscopy among new pulmonary fellows.

Wahidi MM, Silvestri GA, Coakley RD, Ferguson JS, Shepherd RW, Moses L, Conforti J, Que LG, Anstrom KJ, McGuire F, Colt H, Downie GH.

Chest. 2010 May;137(5):1040-9. doi: 10.1378/chest.09-1234. Epub 2009 Oct 26.


S-nitrosoglutathione reductase: an important regulator in human asthma.

Que LG, Yang Z, Stamler JS, Lugogo NL, Kraft M.

Am J Respir Crit Care Med. 2009 Aug 1;180(3):226-31. doi: 10.1164/rccm.200901-0158OC. Epub 2009 Apr 24.


Current teaching and evaluation methods in critical care medicine: has the Accreditation Council for Graduate Medical Education affected how we practice and teach in the intensive care unit?

Chudgar SM, Cox CE, Que LG, Andolsek K, Knudsen NW, Clay AS.

Crit Care Med. 2009 Jan;37(1):49-60. doi: 10.1097/CCM.0b013e31819265c8.


Genetic profiling and tailored therapy in asthma: are we there yet?

Lugogo NL, Ginsburg GS, Que LG.

Curr Opin Mol Ther. 2007 Dec;9(6):528-37. Review.


Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2.

Whalen EJ, Foster MW, Matsumoto A, Ozawa K, Violin JD, Que LG, Nelson CD, Benhar M, Keys JR, Rockman HA, Koch WJ, Daaka Y, Lefkowitz RJ, Stamler JS.

Cell. 2007 May 4;129(3):511-22.


Pharmacologic adjuncts during mechanical ventilation.

Que LG, Tony Huang YC.

Semin Respir Crit Care Med. 2000;21(3):223-32.


Protection from experimental asthma by an endogenous bronchodilator.

Que LG, Liu L, Yan Y, Whitehead GS, Gavett SH, Schwartz DA, Stamler JS.

Science. 2005 Jun 10;308(5728):1618-21. Epub 2005 May 26.


Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock.

Liu L, Yan Y, Zeng M, Zhang J, Hanes MA, Ahearn G, McMahon TJ, Dickfeld T, Marshall HE, Que LG, Stamler JS.

Cell. 2004 Feb 20;116(4):617-28.


Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver.

Yu Q, Que LG, Rockey DC.

Am J Physiol Gastrointest Liver Physiol. 2002 Mar;282(3):G565-72.


Effects of arginase isoforms on NO Production by nNOS.

Que LG, George SE, Gotoh T, Mori M, Huang YC.

Nitric Oxide. 2002 Feb;6(1):1-8.


Malignant melanoma presenting as a mediastinal mass.

Lau CL, Bentley RC, Gockerman JP, Que LG, D'Amico TA.

Ann Thorac Surg. 1999 Mar;67(3):851-2.


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