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Items: 1 to 50 of 96

1.

Aldehyde dehydrogenases inhibition eradicates leukemia stem cells while sparing normal progenitors.

Venton G, Pérez-Alea M, Baier C, Fournet G, Quash G, Labiad Y, Martin G, Sanderson F, Poullin P, Suchon P, Farnault L, Nguyen C, Brunet C, Ceylan I, Costello RT.

Blood Cancer J. 2016 Sep 9;6(9):e469. doi: 10.1038/bcj.2016.78.

4.

Synergetic bitherapy in mice with xenografts of human prostate cancer using a methional mimic (METLICO) and an aldehyde dehydrogenase 3 inhibitor (MATE): systemic intraperitoneal (IP) and targeted intra-tumoral (IT) administration.

Hiltbrand E, Fournet G, Giliberto JP, Paret MJ, Chantepie J, Morel D, Goré J, Reichert U, Mehier H, Rochedix ME, Quash G.

Curr Med Chem. 2009;16(10):1184-91.

PMID:
19355878
5.

Towards a biosensor immunoassay of protein-bound isopeptides in human plasma.

Bergstrand A, Ceylan I, Quash G, Nydén M, Holmberg K.

Colloids Surf B Biointerfaces. 2008 Oct 1;66(1):150-3. doi: 10.1016/j.colsurfb.2008.06.001. Epub 2008 Jun 13.

PMID:
18621513
6.

Aldehyde dehydrogenase inhibitors: alpha,beta-acetylenic N-substituted aminothiolesters are reversible growth inhibitors of normal epithelial but irreversible apoptogens for cancer epithelial cells from human prostate in culture.

Quash G, Fournet G, Courvoisier C, Martinez RM, Chantepie J, Paret MJ, Pharaboz J, Joly-Pharaboz MO, Goré J, André J, Reichert U.

Eur J Med Chem. 2008 May;43(5):906-16. Epub 2007 Jul 6.

PMID:
17692435
7.

A role for tissue transglutaminase in alpha-gliadin peptide cytotoxicity.

Sakly W, Thomas V, Quash G, El Alaoui S.

Clin Exp Immunol. 2006 Dec;146(3):550-8.

8.

Synthesis and effects of 3-methylthiopropanoyl thiolesters of lipoic acid, methional metabolite mimics.

Courvoisier C, Paret MJ, Chantepie J, Goré J, Fournet G, Quash G.

Bioorg Chem. 2006 Feb;34(1):49-58. Epub 2006 Jan 4.

PMID:
16387348
9.

Development and evaluation of a modified colorimetric solid-phase microassay for measuring the activity of cellular and plasma (Factor XIII) transglutaminases.

Thomas V, El Alaoui S, Massignon D, Clément S, Simonet F, Quash G.

Biotechnol Appl Biochem. 2006 Mar;43(Pt 3):171-9.

PMID:
16313237
10.
11.

4-methylthio 2-oxobutanoate transaminase: a specific target for antiproliferative agents.

Quash G, Roch AM, Charlot C, Chantepie J, Thomas V, Hamedi-Sangsari F, Vila J.

Bull Cancer. 2004 Apr;91(4):E61-79.

12.

Definition of the fine specificity of the monoclonal antibody 81D4: its reactivity with lysine and polyamine isopeptide cross-links.

Thomas V, Fournet G, Simonet F, Roch AM, Ceylan I, El Alaouia S, Quash G.

J Immunol Methods. 2004 Sep;292(1-2):83-95.

PMID:
15350514
13.

Survival after gamma interferon intratumoral injections in a model of hepatocarcinoma.

Peyrègne V, Quash G, Isaac S, Chantepie J, Akiba H, Scoazec JY, Gilly FN.

Hepatogastroenterology. 2004 Jul-Aug;51(58):1115-20.

PMID:
15239257
14.

Anaplerotic reactions in tumour proliferation and apoptosis.

Quash G, Fournet G, Reichert U.

Biochem Pharmacol. 2003 Aug 1;66(3):365-70. Review.

PMID:
12907234
15.
16.
17.

The effect of a novel irreversible inhibitor of aldehyde dehydrogenases 1 and 3 on tumour cell growth and death.

Canuto RA, Muzio G, Salvo RA, Maggiora M, Trombetta A, Chantepie J, Fournet G, Reichert U, Quash G.

Chem Biol Interact. 2001 Jan 30;130-132(1-3):209-18.

PMID:
11306045
18.

A thioester analogue of an amino acetylenic aldehyde is a suicide inhibitor of aldehyde dehydrogenase and an inducer of apoptosis in mouse lymphoid cells overexpressing the bcl2 gene.

Quash G, Fournet G, Raffin C, Chantepie J, Michal Y, Gore J, Reichert U.

Adv Exp Med Biol. 1999;463:97-106. No abstract available.

PMID:
10352674
19.
20.

A novel synthetic reversible inhibitor of sialidase efficiently blocks secondary but not primary influenza virus infection of MDCK cells in culture.

Barrêre B, Driguez PA, Maudrin J, Doutheau A, Aymard M, Quash G.

Arch Virol. 1997 Jul;142(7):1365-1380. doi: 10.1007/s007050050166.

PMID:
28879398
21.
22.

A novel synthetic reversible inhibitor of sialidase efficiently blocks secondary but not primary influenza virus infection of MDCK cells in culture.

Barrère B, Driguez PA, Maudrin J, Doutheau A, Aymard M, Quash G.

Arch Virol. 1997;142(7):1365-80.

PMID:
9267449
23.
24.

Altered methional homoeostasis is associated with decreased apoptosis in BAF3 bcl2 murine lymphoid cells.

Roch AM, Quash G, Michal Y, Chantepie J, Chantegrel B, Deshayes C, Doutheau A, Marvel J.

Biochem J. 1996 Feb 1;313 ( Pt 3):973-81.

25.

Effects of Hydrophilization and Immobilization on the Interfacial Behavior of Immunoglobulins.

Malmsten M, Lassen B, Holmberg K, Thomas V V, Quash G.

J Colloid Interface Sci. 1996 Jan 15;177(1):70-78.

PMID:
10479418
26.

Methionine dependence of tumor cells: programmed cell survival?

Dumontet C, Roch AM, Quash G.

Oncol Res. 1996;8(12):469-71.

PMID:
9160350
27.

The structure of polyamine analogues determines haemoglobin production and cytotoxicity in murine erythroleukaemia cells.

Clément S, Delcros JG, Basu HS, Quash G, Marton LJ, Feuerstein BG.

Biochem J. 1995 Aug 1;309 ( Pt 3):787-91.

28.

Methional derived from 4-methylthio-2-oxobutanoate is a cellular mediator of apoptosis in BAF3 lymphoid cells.

Quash G, Roch AM, Chantepie J, Michal Y, Fournet G, Dumontet C.

Biochem J. 1995 Feb 1;305 ( Pt 3):1017-25.

29.

Synthesis of transition-state analogues as potential inhibitors of sialidase from Influenza virus.

Driguez PA, Barrere B, Quash G, Doutheau A.

Carbohydr Res. 1994 Sep 15;262(2):297-310.

PMID:
7982221
30.

Naturally occurring antibodies reacting with lipoic acid: screening method, characterization and biochemical interest.

Legastelois S, Thomas V, Quash G, Métais MP, Tebib J, Moreira A, Monier JC.

J Immunol Methods. 1994 May 2;171(1):111-9.

PMID:
8176232
31.

Inactivation of human cytomegalovirus by sodium periodate oxidation.

Geoffroy F, Ogier G, Chantepie J, Quash G.

Arch Virol. 1994;135(1-2):61-74.

PMID:
8198450
32.

Inhibition of type 5 adenovirus infectivity by periodate oxidation.

Ogier G, Michal Y, Thomas V, Quash G, Rodwell JD.

Arch Virol. 1994;135(1-2):43-60.

PMID:
8198449
33.

Contribution of 4-methylthio-2-oxobutanoate and its transaminase to the growth of methionine-dependent cells in culture. Effect of transaminase inhibitors.

Ogier G, Chantepie J, Deshayes C, Chantegrel B, Charlot C, Doutheau A, Quash G.

Biochem Pharmacol. 1993 Apr 22;45(8):1631-44.

PMID:
8484803
34.

Immunization of rabbits with spermine induces antibodies to self antigens.

Atanassov CL, Delcros JG, Muller S, Quash G, Van Regenmortel MH.

Int Arch Allergy Immunol. 1993;102(1):46-55.

PMID:
8400885
35.

Cell cycle kinetics, tissue transglutaminase and programmed cell death (apoptosis).

el Alaoui S, Mian S, Lawry J, Quash G, Griffin M.

FEBS Lett. 1992 Oct 19;311(2):174-8.

37.

Transglutaminase activity and N epsilon (gamma glutamyl) lysine isopeptide levels during cell growth: an enzymic and immunological study.

el Alaoui S, Legastelois S, Roch AM, Chantepie J, Quash G.

Int J Cancer. 1991 May 10;48(2):221-6.

PMID:
1673452
38.
39.
42.

Synthesis of acetylenic spirobutenolide derivatives and evaluation of their growth inhibitory effect on cells in culture.

Bador P, Chantepie J, Paris J, Quash G.

Arzneimittelforschung. 1990 Oct;40(10):1135-9.

PMID:
2291752
43.

Aldehyde dehydrogenase activity in xenografted human brain tumor in nude mice. Preliminary results in human glioma biopsies.

Quemener V, Moulinoux JP, Martin C, Darcel F, Guegan Y, Faivre J, Quash GA.

J Neurooncol. 1990 Oct;9(2):115-23.

PMID:
2262798
44.

[Polyamine metabolism errors in colorectal polyps and adenocarcinoma of human origin].

Lointier P, Pezet D, Roch AM, Quash G, Chipponi J.

Gastroenterol Clin Biol. 1989 Nov;13(11):946-7. French. No abstract available.

PMID:
2612836
45.

In vivo antitumor activity of 4-amino 4-methyl 2-pentyne 1-al, an inhibitor of aldehyde dehydrogenase.

Quemener V, Quash G, Moulinoux JP, Penlap V, Ripoll H, Havouis R, Doutheau A, Goré J.

In Vivo. 1989 Sep-Oct;3(5):325-30.

PMID:
2519873
46.

The effect of a novel inhibitor of aldehyde dehydrogenase on viral replication.

Ogier G, Chantepie J, Quash G, Doutheau A, Gore J, Marion C.

Biochem Pharmacol. 1989 Apr 15;38(8):1335-43.

PMID:
2706022
47.

Diagnostic and therapeutic procedures with haptens and glycoproteins (antigens and antibodies) coupled covalently by specific sites to insoluble supports.

Quash GA, Thomas V, Ogier G, el Alaoui S, Delcros JG, Ripoll H, Roch AM, Legastelois S, Gibert R, Ripoll JP.

Targeted Diagn Ther. 1989;2:155-86. No abstract available.

PMID:
2519545
48.

Protein-bound polyamines in the plasma of mice grafted with the Lewis lung carcinoma.

Delcros JG, Roch AM, Thomas V, el Alaoui S, Moulinoux JP, Quash G.

FEBS Lett. 1987 Aug 10;220(1):236-42.

49.

Malondialdehyde production from spermine by homogenates of normal and transformed cells.

Quash G, Ripoll H, Gazzolo L, Doutheau A, Saba A, Gore J.

Biochimie. 1987 Feb;69(2):101-8.

PMID:
3032285
50.

[Demonstration of polyamines bound to plasma proteins during tumor growth].

Delcros JG, Roch AM, Thomas V, el Alaoui S, Moulinoux JP, Quash G.

C R Acad Sci III. 1987;305(12):465-70. French.

PMID:
3121140

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