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Items: 44

1.

Cytokines trigger disruption of endothelium barrier function and p38 MAP kinase activation in BMPR2-silenced human lung microvascular endothelial cells.

Tielemans B, Stoian L, Gijsbers R, Michiels A, Wagenaar A, Farre Marti R, Belge C, Delcroix M, Quarck R.

Pulm Circ. 2019 Oct 23;9(4):2045894019883607. doi: 10.1177/2045894019883607. eCollection 2019 Oct-Dec.

2.

CCR2/CCR5-mediated macrophage-smooth muscle cell crosstalk in pulmonary hypertension.

Abid S, Marcos E, Parpaleix A, Amsellem V, Breau M, Houssaini A, Vienney N, Lefevre M, Derumeaux G, Evans S, Hubeau C, Delcroix M, Quarck R, Adnot S, Lipskaia L.

Eur Respir J. 2019 Oct 10;54(4). pii: 1802308. doi: 10.1183/13993003.02308-2018. Print 2019 Oct.

PMID:
31320454
3.

Double-lung versus heart-lung transplantation for precapillary pulmonary arterial hypertension: a 24-year single-center retrospective study.

Brouckaert J, Verleden SE, Verbelen T, Coosemans W, Decaluwé H, De Leyn P, Depypere L, Nafteux P, Van Veer H, Meyns B, Rega F, Van De Velde M, Poortmans G, Rex S, Neyrinck A, Van den Berghe G, Vlasselaers D, Van Cleemput J, Budts W, Vos R, Quarck R, Belge C, Delcroix M, Verleden GM, Van Raemdonck D.

Transpl Int. 2019 Jul;32(7):717-729. doi: 10.1111/tri.13409. Epub 2019 Mar 5.

PMID:
30735591
4.

TGFβ and BMPRII signalling pathways in the pathogenesis of pulmonary arterial hypertension.

Tielemans B, Delcroix M, Belge C, Quarck R.

Drug Discov Today. 2019 Mar;24(3):703-716. doi: 10.1016/j.drudis.2018.12.001. Epub 2018 Dec 7. Review.

PMID:
30529762
5.

Rescuing BMPR2-driven endothelial dysfunction in PAH: a novel treatment strategy for the future?

Quarck R, Perros F.

Stem Cell Investig. 2017 Jun 14;4:56. doi: 10.21037/sci.2017.05.11. eCollection 2017. No abstract available.

6.

BMPRII influences the response of pulmonary microvascular endothelial cells to inflammatory mediators.

Vengethasamy L, Hautefort A, Tielemans B, Belge C, Perros F, Verleden S, Fadel E, Van Raemdonck D, Delcroix M, Quarck R.

Pflugers Arch. 2016 Nov;468(11-12):1969-1983. Epub 2016 Nov 6.

PMID:
27816994
7.

Progressive Vascular Functional and Structural Damage in a Bronchopulmonary Dysplasia Model in Preterm Rabbits Exposed to Hyperoxia.

Jiménez J, Richter J, Nagatomo T, Salaets T, Quarck R, Wagennar A, Wang H, Vanoirbeek J, Deprest J, Toelen J.

Int J Mol Sci. 2016 Oct 24;17(10). pii: E1776.

8.

Osteopontin, a Key Mediator Expressed by Senescent Pulmonary Vascular Cells in Pulmonary Hypertension.

Saker M, Lipskaia L, Marcos E, Abid S, Parpaleix A, Houssaini A, Validire P, Girard P, Noureddine H, Boyer L, Vienney N, Amsellem V, Marguerit L, Maitre B, Derumeaux G, Dubois-Rande JL, Jourdan-Lesaux C, Delcroix M, Quarck R, Adnot S.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1879-90. doi: 10.1161/ATVBAHA.116.307839. Epub 2016 Jul 21.

PMID:
27444202
9.

Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension.

Parpaleix A, Amsellem V, Houssaini A, Abid S, Breau M, Marcos E, Sawaki D, Delcroix M, Quarck R, Maillard A, Couillin I, Ryffel B, Adnot S.

Eur Respir J. 2016 Aug;48(2):470-83. doi: 10.1183/13993003.01448-2015. Epub 2016 Jul 13.

10.

Letter by Belge et al Regarding Article, "Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models".

Belge C, Quarck R, Delcroix M.

Circulation. 2016 Apr 5;133(14):e591. doi: 10.1161/CIRCULATIONAHA.115.018683. No abstract available.

PMID:
27045135
11.

Extracellular Calpain/Calpastatin Balance Is Involved in the Progression of Pulmonary Hypertension.

Wan F, Letavernier E, Abid S, Houssaini A, Czibik G, Marcos E, Rideau D, Parpaleix A, Lipskaia L, Amsellem V, Gellen B, Sawaki D, Derumeaux G, Dubois-Randé JL, Delcroix M, Quarck R, Baud L, Adnot S.

Am J Respir Cell Mol Biol. 2016 Sep;55(3):337-51. doi: 10.1165/rcmb.2015-0257OC.

PMID:
26974350
12.

Contribution of inflammation and impaired angiogenesis to the pathobiology of chronic thromboembolic pulmonary hypertension.

Quarck R, Wynants M, Verbeken E, Meyns B, Delcroix M.

Eur Respir J. 2015 Aug;46(2):431-43. doi: 10.1183/09031936.00009914. Epub 2015 Jun 25.

13.

Role for telomerase in pulmonary hypertension.

Mouraret N, Houssaïni A, Abid S, Quarck R, Marcos E, Parpaleix A, Gary-Bobo G, Dubois-Randé JL, Derumeaux G, Boczkowski J, Delcroix M, Blasco MA, Lipskaia L, Amsellem V, Adnot S.

Circulation. 2015 Feb 24;131(8):742-755. doi: 10.1161/CIRCULATIONAHA.114.013258. Epub 2014 Dec 30.

14.

Chemotherapy-induced pulmonary hypertension: role of alkylating agents.

Ranchoux B, Günther S, Quarck R, Chaumais MC, Dorfmüller P, Antigny F, Dumas SJ, Raymond N, Lau E, Savale L, Jaïs X, Sitbon O, Simonneau G, Stenmark K, Cohen-Kaminsky S, Humbert M, Montani D, Perros F.

Am J Pathol. 2015 Feb;185(2):356-71. doi: 10.1016/j.ajpath.2014.10.021. Epub 2014 Dec 11. Review.

PMID:
25497573
15.

Is inflammation a potential therapeutic target in chronic thromboembolic pulmonary hypertension?

Quarck R, Delcroix M.

Eur Respir J. 2014 Oct;44(4):842-5. doi: 10.1183/09031936.00120014. No abstract available.

16.

CCR5 as a treatment target in pulmonary arterial hypertension.

Amsellem V, Lipskaia L, Abid S, Poupel L, Houssaini A, Quarck R, Marcos E, Mouraret N, Parpaleix A, Bobe R, Gary-Bobo G, Saker M, Dubois-Randé JL, Gladwin MT, Norris KA, Delcroix M, Combadière C, Adnot S.

Circulation. 2014 Sep 9;130(11):880-891. doi: 10.1161/CIRCULATIONAHA.114.010757. Epub 2014 Jul 3.

17.

NF-κB pathway is involved in CRP-induced effects on pulmonary arterial endothelial cells in chronic thromboembolic pulmonary hypertension.

Wynants M, Vengethasamy L, Ronisz A, Meyns B, Delcroix M, Quarck R.

Am J Physiol Lung Cell Mol Physiol. 2013 Dec;305(12):L934-42. doi: 10.1152/ajplung.00034.2013. Epub 2013 Oct 4.

18.

Measurement of right ventricular pressure by telemetry in conscious moving rabbits.

Ronisz A, Delcroix M, Quarck R.

Lab Anim. 2013 Jul;47(3):175-183.

PMID:
23579323
19.

Amorphous silica nanoparticles promote monocyte adhesion to human endothelial cells: size-dependent effect.

Napierska D, Quarck R, Thomassen LC, Lison D, Martens JA, Delcroix M, Nemery B, Hoet PH.

Small. 2013 Feb 11;9(3):430-8. doi: 10.1002/smll.201201033. Epub 2012 Oct 8.

PMID:
23042701
20.

Characterization of proximal pulmonary arterial cells from chronic thromboembolic pulmonary hypertension patients.

Quarck R, Wynants M, Ronisz A, Sepulveda MR, Wuytack F, Van Raemdonck D, Meyns B, Delcroix M.

Respir Res. 2012 Mar 27;13:27. doi: 10.1186/1465-9921-13-27.

21.

Effects of C-reactive protein on human pulmonary vascular cells in chronic thromboembolic pulmonary hypertension.

Wynants M, Quarck R, Ronisz A, Alfaro-Moreno E, Van Raemdonck D, Meyns B, Delcroix M.

Eur Respir J. 2012 Oct;40(4):886-94. Epub 2012 Jan 20.

22.

Long-term outcome in pulmonary arterial hypertension: a plea for earlier parenteral prostacyclin therapy.

Delcroix M, Spaas K, Quarck R.

Eur Respir Rev. 2009 Dec;18(114):253-9. doi: 10.1183/09059180.00003109. Review.

23.

C-reactive protein: a new predictor of adverse outcome in pulmonary arterial hypertension.

Quarck R, Nawrot T, Meyns B, Delcroix M.

J Am Coll Cardiol. 2009 Apr 7;53(14):1211-8. doi: 10.1016/j.jacc.2008.12.038.

24.

Markers of inflammation and disuse in vastus lateralis of chronic obstructive pulmonary disease patients.

Crul T, Spruit MA, Gayan-Ramirez G, Quarck R, Gosselink R, Troosters T, Pitta F, Decramer M.

Eur J Clin Invest. 2007 Nov;37(11):897-904. Epub 2007 Sep 20.

PMID:
17883420
25.

Human paraoxonase-1 overexpression inhibits atherosclerosis in a mouse model of metabolic syndrome.

Mackness B, Quarck R, Verreth W, Mackness M, Holvoet P.

Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1545-50. Epub 2006 Apr 20.

PMID:
16627808
26.

Effect of adenovirus-mediated gene transfer of nitric oxide synthase on vascular reactivity of rat isolated pulmonary arteries.

Jiang L, Quarck R, Janssens S, Pokreisz P, Demedts M, Delcroix M.

Pflugers Arch. 2006 May;452(2):213-21. Epub 2006 Jan 11.

PMID:
16404609
27.

Weight-loss-associated induction of peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-gamma correlate with reduced atherosclerosis and improved cardiovascular function in obese insulin-resistant mice.

Verreth W, De Keyzer D, Pelat M, Verhamme P, Ganame J, Bielicki JK, Mertens A, Quarck R, Benhabilès N, Marguerie G, Mackness B, Mackness M, Ninio E, Herregods MC, Balligand JL, Holvoet P.

Circulation. 2004 Nov 16;110(20):3259-69. Epub 2004 Nov 8.

PMID:
15533870
28.

Gene therapy approaches for cardiovascular diseases.

Quarck R, Holvoet P.

Curr Gene Ther. 2004 Jun;4(2):207-23. Review.

PMID:
15180587
29.

Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis.

Mertens A, Verhamme P, Bielicki JK, Phillips MC, Quarck R, Verreth W, Stengel D, Ninio E, Navab M, Mackness B, Mackness M, Holvoet P.

Circulation. 2003 Apr 1;107(12):1640-6. Epub 2003 Mar 24.

PMID:
12668499
30.

Dietary cholesterol withdrawal reduces vascular inflammation and induces coronary plaque stabilization in miniature pigs.

Verhamme P, Quarck R, Hao H, Knaapen M, Dymarkowski S, Bernar H, Van Cleemput J, Janssens S, Vermylen J, Gabbiani G, Kockx M, Holvoet P.

Cardiovasc Res. 2002 Oct;56(1):135-44.

PMID:
12237174
31.

Hypercholesterolemia impairs vascular remodelling after porcine coronary angioplasty.

Theilmeier G, Quarck R, Verhamme P, Bochaton-Piallat ML, Lox M, Bernar H, Janssens S, Kockx M, Gabbiani G, Collen D, Holvoet P.

Cardiovasc Res. 2002 Aug 1;55(2):385-95.

PMID:
12123778
32.

Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors.

Michiels C, Renard P, Bouaziz N, Heck N, Eliaers F, Ninane N, Quarck R, Holvoet P, Raes M.

Biochem Pharmacol. 2002 Jan 15;63(2):321-32.

PMID:
11841807
33.

Arg123-Tyr166 domain of human ApoA-I is critical for HDL-mediated inhibition of macrophage homing and early atherosclerosis in mice.

Holvoet P, Peeters K, Lund-Katz S, Mertens A, Verhamme P, Quarck R, Stengel D, Lox M, Deridder E, Bernar H, Nickel M, Theilmeier G, Ninio E, Phillips MC.

Arterioscler Thromb Vasc Biol. 2001 Dec;21(12):1977-83.

PMID:
11742873
34.

Restenosis and gene therapy.

Quarck R, Holvoet P.

Expert Opin Biol Ther. 2001 Jan;1(1):79-91. Review.

PMID:
11727549
35.

Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice.

Quarck R, De Geest B, Stengel D, Mertens A, Lox M, Theilmeier G, Michiels C, Raes M, Bult H, Collen D, Van Veldhoven P, Ninio E, Holvoet P.

Circulation. 2001 May 22;103(20):2495-500.

PMID:
11369691
36.

Smooth muscle cell cycle and proliferation. Relationship between calcium influx and sarco-endoplasmic reticulum Ca2+ATPase regulation.

Magnier-Gaubil C, Herbert JM, Quarck R, Papp B, Corvazier E, Wuytack F, Lévy-Tolédano S, Enouf J.

J Biol Chem. 1996 Nov 1;271(44):27788-94.

37.

Differential up-regulation of Rap1a and Rap1b proteins during smooth muscle cell cycle.

Quarck R, Berrou E, Magnier C, Bobe R, Bredoux R, Tobelem G, Enouf J, Bryckaert M.

Eur J Cell Biol. 1996 Jul;70(3):269-77.

PMID:
8832211
38.

Transforming growth factor beta 1 inhibits mitogen-activated protein kinase induced by basic fibroblast growth factor in smooth muscle cells.

Berrou E, Fontenay-Roupie M, Quarck R, McKenzie FR, Lévy-Toledano S, Tobelem G, Bryckaert M.

Biochem J. 1996 May 15;316 ( Pt 1):167-73.

39.
40.

Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes.

Berger G, Quarck R, Tenza D, Levy-Toledano S, de Gunzburg J, Cramer EM.

Br J Haematol. 1994 Oct;88(2):372-82.

PMID:
7803284
41.

Evidence for Rap1 in vascular smooth muscle cells. Regulation of their expression by platelet-derived growth factor BB.

Quarck R, Bryckaert M, Magnier C, Corvazier E, Bredoux R, de Gunzburg J, Fontenay M, Tobelem G, Enouf J.

FEBS Lett. 1994 Apr 4;342(2):159-64.

42.

Abnormal cAMP-induced phosphorylation of rap 1 protein in grey platelet syndrome platelets.

Enouf J, Corvazier E, Papp B, Quarck R, Magnier C, Kovàcs T, Bredoux R, Lévy-Tolédano S, de Gunzburg J, Wuytack F, et al.

Br J Haematol. 1994 Feb;86(2):338-46.

PMID:
8199024
43.

Correlated expression of the 97 kDa sarcoendoplasmic reticulum Ca(2+)-ATPase and Rap1B in platelets and various cell lines.

Magnier C, Bredoux R, Kovacs T, Quarck R, Papp B, Corvazier E, de Gunzburg J, Enouf J.

Biochem J. 1994 Jan 15;297 ( Pt 2):343-50.

44.

The rat platelet 97-kDa Ca2+ATPase isoform is the sarcoendoplasmic reticulum Ca2+ATPase 3 protein.

Bobe R, Bredoux R, Wuytack F, Quarck R, Kovàcs T, Papp B, Corvazier E, Magnier C, Enouf J.

J Biol Chem. 1994 Jan 14;269(2):1417-24.

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