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Items: 1 to 50 of 127

1.

Ultrastructural variability of the juxtacanalicular tissue along the inner wall of Schlemm's canal.

Koudouna E, Young RD, Overby DR, Ueno M, Kinoshita S, Knupp C, Quantock AJ.

Mol Vis. 2019 Sep 21;25:517-526. eCollection 2019.

2.

Cell-independent matrix configuration in early corneal development.

Young RD, Knupp C, Koudouna E, Ralphs JR, Ma Y, Lwigale PY, Jester JV, Quantock AJ.

Exp Eye Res. 2019 Oct;187:107772. doi: 10.1016/j.exer.2019.107772. Epub 2019 Aug 21.

3.

Hyperlipidemia induces meibomian gland dysfunction.

Bu J, Wu Y, Cai X, Jiang N, Jeyalatha MV, Yu J, He X, He H, Guo Y, Zhang M, Quantock AJ, Liu Z, Li W.

Ocul Surf. 2019 Oct;17(4):777-786. doi: 10.1016/j.jtos.2019.06.002. Epub 2019 Jun 13.

PMID:
31201956
4.

Recovering vision in corneal epithelial stem cell deficient eyes.

Bains KK, Fukuoka H, Hammond GM, Sotozono C, Quantock AJ.

Cont Lens Anterior Eye. 2019 Aug;42(4):350-358. doi: 10.1016/j.clae.2019.04.006. Epub 2019 Apr 29. Review.

5.

CD200 facilitates the isolation of corneal epithelial cells derived from human pluripotent stem cells.

Hayashi R, Ishikawa Y, Katayama T, Quantock AJ, Nishida K.

Sci Rep. 2018 Nov 8;8(1):16550. doi: 10.1038/s41598-018-34845-2.

6.

Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages.

Shibata S, Hayashi R, Okubo T, Kudo Y, Katayama T, Ishikawa Y, Toga J, Yagi E, Honma Y, Quantock AJ, Sekiguchi K, Nishida K.

Cell Rep. 2018 Nov 6;25(6):1668-1679.e5. doi: 10.1016/j.celrep.2018.10.032.

7.

Microwave treatment of the cornea leads to localised disruption of the extracellular matrix.

Morgan SR, Hieda O, Nakai Y, Boote C, Hayes S, Kinoshita S, Meek KM, Quantock AJ.

Sci Rep. 2018 Sep 13;8(1):13742. doi: 10.1038/s41598-018-32110-0.

8.

Cell regulation of collagen fibril macrostructure during corneal morphogenesis.

Koudouna E, Mikula E, Brown DJ, Young RD, Quantock AJ, Jester JV.

Acta Biomater. 2018 Oct 1;79:96-112. doi: 10.1016/j.actbio.2018.08.017. Epub 2018 Aug 29.

9.

Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7-Null Mouse Cornea.

Littlechild SL, Young RD, Caterson B, Yoshida H, Yamazaki M, Sakimura K, Quantock AJ, Akama TO.

Invest Ophthalmol Vis Sci. 2018 Mar 1;59(3):1641-1651. doi: 10.1167/iovs.17-22716.

10.

Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells.

Kobayashi Y, Hayashi R, Quantock AJ, Nishida K.

Stem Cell Res. 2017 Dec;25:256-265. doi: 10.1016/j.scr.2017.10.015. Epub 2017 Oct 31.

11.

New Graft Insertion Device for Descemet Stripping Automated Endothelial Keratoplasty.

Soma T, Koh S, Maeda N, Mitomo K, Quantock AJ, Nishida K.

Cornea. 2017 Nov;36(11):1432-1436. doi: 10.1097/ICO.0000000000001302.

PMID:
28777101
12.

Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy.

Okumura N, Kitahara M, Okuda H, Hashimoto K, Ueda E, Nakahara M, Kinoshita S, Young RD, Quantock AJ, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N.

Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3697-3707. doi: 10.1167/iovs.16-21023.

PMID:
28727885
13.

A Surgical Cryoprobe for Targeted Transcorneal Freezing and Endothelial Cell Removal.

Akhbanbetova A, Nakano S, Littlechild SL, Young RD, Zvirgzdina M, Fullwood NJ, Weston I, Weston P, Kinoshita S, Okumura N, Koizumi N, Quantock AJ.

J Ophthalmol. 2017;2017:5614089. doi: 10.1155/2017/5614089. Epub 2017 May 16.

14.

Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells.

Hayashi R, Ishikawa Y, Katori R, Sasamoto Y, Taniwaki Y, Takayanagi H, Tsujikawa M, Sekiguchi K, Quantock AJ, Nishida K.

Nat Protoc. 2017 Apr;12(4):683-696. doi: 10.1038/nprot.2017.007. Epub 2017 Mar 2.

PMID:
28253236
15.

Topical delivery of a Rho-kinase inhibitor to the cornea via mucoadhesive film.

Chan W, Akhbanbetova A, Quantock AJ, Heard CM.

Eur J Pharm Sci. 2016 Aug 25;91:256-64. doi: 10.1016/j.ejps.2016.05.016. Epub 2016 May 16.

16.

Co-ordinated ocular development from human iPS cells and recovery of corneal function.

Hayashi R, Ishikawa Y, Sasamoto Y, Katori R, Nomura N, Ichikawa T, Araki S, Soma T, Kawasaki S, Sekiguchi K, Quantock AJ, Tsujikawa M, Nishida K.

Nature. 2016 Mar 17;531(7594):376-80. doi: 10.1038/nature17000. Epub 2016 Mar 9.

PMID:
26958835
17.

PAX6 Isoforms, along with Reprogramming Factors, Differentially Regulate the Induction of Cornea-specific Genes.

Sasamoto Y, Hayashi R, Park SJ, Saito-Adachi M, Suzuki Y, Kawasaki S, Quantock AJ, Nakai K, Tsujikawa M, Nishida K.

Sci Rep. 2016 Feb 22;6:20807. doi: 10.1038/srep20807.

18.

Mesenchymal-epithelial cell interactions and proteoglycan matrix composition in the presumptive stem cell niche of the rabbit corneal limbus.

Yamada K, Young RD, Lewis PN, Shinomiya K, Meek KM, Kinoshita S, Caterson B, Quantock AJ.

Mol Vis. 2015 Dec 29;21:1328-39. eCollection 2015.

19.

Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy.

Okumura N, Minamiyama R, Ho LT, Kay EP, Kawasaki S, Tourtas T, Schlötzer-Schrehardt U, Kruse FE, Young RD, Quantock AJ, Kinoshita S, Koizumi N.

Lab Invest. 2015 Nov;95(11):1291-304. doi: 10.1038/labinvest.2015.111. Epub 2015 Aug 24.

20.

From nano to macro: studying the hierarchical structure of the corneal extracellular matrix.

Quantock AJ, Winkler M, Parfitt GJ, Young RD, Brown DJ, Boote C, Jester JV.

Exp Eye Res. 2015 Apr;133:81-99. doi: 10.1016/j.exer.2014.07.018. Review.

21.

Dynamic studies of human corneal fibroblasts.

Quantock AJ.

Invest Ophthalmol Vis Sci. 2015 Mar 25;56(3):2091. doi: 10.1167/iovs.15-16836. No abstract available.

PMID:
25808420
22.

A comparison of glycosaminoglycan distributions, keratan sulphate sulphation patterns and collagen fibril architecture from central to peripheral regions of the bovine cornea.

Ho LT, Harris AM, Tanioka H, Yagi N, Kinoshita S, Caterson B, Quantock AJ, Young RD, Meek KM.

Matrix Biol. 2014 Sep;38:59-68. doi: 10.1016/j.matbio.2014.06.004. Epub 2014 Jul 11.

23.

Three-dimensional architecture of collagen type VI in the human trabecular meshwork.

Koudouna E, Young RD, Ueno M, Kinoshita S, Quantock AJ, Knupp C.

Mol Vis. 2014 May 13;20:638-48. eCollection 2014.

24.

The emerging roles of TCF4 in disease and development.

Forrest MP, Hill MJ, Quantock AJ, Martin-Rendon E, Blake DJ.

Trends Mol Med. 2014 Jun;20(6):322-31. doi: 10.1016/j.molmed.2014.01.010. Epub 2014 Mar 1. Review.

PMID:
24594265
25.

Three-dimensional aspects of matrix assembly by cells in the developing cornea.

Young RD, Knupp C, Pinali C, Png KM, Ralphs JR, Bushby AJ, Starborg T, Kadler KE, Quantock AJ.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):687-92. doi: 10.1073/pnas.1313561110. Epub 2014 Jan 2.

26.

X-ray absorption near-edge structure (XANES) spectroscopy identifies differential sulfur speciation in corneal tissue.

Veronesi G, Koudouna E, Cotte M, Martin FL, Quantock AJ.

Anal Bioanal Chem. 2013 Aug;405(21):6613-20. doi: 10.1007/s00216-013-7120-x. Epub 2013 Jun 19.

PMID:
23780227
27.

The effect of riboflavin/UVA collagen cross-linking therapy on the structure and hydrodynamic behaviour of the ungulate and rabbit corneal stroma.

Hayes S, Kamma-Lorger CS, Boote C, Young RD, Quantock AJ, Rost A, Khatib Y, Harris J, Yagi N, Terrill N, Meek KM.

PLoS One. 2013;8(1):e52860. doi: 10.1371/journal.pone.0052860. Epub 2013 Jan 17.

28.

A study of host corneal endothelial cells after non-Descemet stripping automated endothelial keratoplasty.

Hatanaka H, Koizumi N, Okumura N, Takahashi H, Tanioka H, Young RD, Jones FE, Quantock AJ, Kinoshita S.

Cornea. 2013 Jan;32(1):76-80. doi: 10.1097/ICO.0b013e31825d568a.

PMID:
22968356
29.

Chemical composition and sulfur speciation in bulk tissue by x-ray spectroscopy and x-ray microscopy: corneal development during embryogenesis.

Koudouna E, Veronesi G, Patel II, Cotte M, Knupp C, Martin FL, Quantock AJ.

Biophys J. 2012 Jul 18;103(2):357-64. doi: 10.1016/j.bpj.2012.05.036. Epub 2012 Jul 17.

30.

A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma.

Yamamoto M, Quantock AJ, Young RD, Okumura N, Ueno M, Sakamoto Y, Kinoshita S, Koizumi N.

Mol Vis. 2012;18:1727-39. Epub 2012 Jun 27.

31.

Optical mechanical refinement of human amniotic membrane by dehydration and cross-linking.

Tanaka Y, Kubota A, Yokokura S, Uematsu M, Shi D, Yamato M, Okano T, Quantock AJ, Nishida K.

J Tissue Eng Regen Med. 2012 Oct;6(9):731-7. doi: 10.1002/term.479. Epub 2012 Apr 4.

PMID:
22489071
32.

Ultraviolet light transmission through the human corneal stroma is reduced in the periphery.

Doutch JJ, Quantock AJ, Joyce NC, Meek KM.

Biophys J. 2012 Mar 21;102(6):1258-64. doi: 10.1016/j.bpj.2012.02.023. Epub 2012 Mar 20.

33.

Alterations in the biomolecular signatures of developing chick corneas as determined by biospectroscopy and multivariate analysis.

Pang W, Ahmadzai AA, Patel II, Qiu X, Liles M, Quantock AJ, Martin FL.

Invest Ophthalmol Vis Sci. 2012 Mar 9;53(3):1162-8. doi: 10.1167/iovs.11-9262.

PMID:
22273722
34.

Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma.

Hayes S, Boote C, Kamma-Lorger CS, Rajan MS, Harris J, Dooley E, Hawksworth N, Hiller J, Terill NJ, Hafezi F, Brahma AK, Quantock AJ, Meek KM.

PLoS One. 2011;6(8):e22405. doi: 10.1371/journal.pone.0022405. Epub 2011 Aug 5.

35.

Fibroblast growth factor 2 and transforming growth factor β1 induce precocious maturation of articular cartilage.

Khan IM, Evans SL, Young RD, Blain EJ, Quantock AJ, Avery N, Archer CW.

Arthritis Rheum. 2011 Nov;63(11):3417-27. doi: 10.1002/art.30543.

36.

Large proteoglycan complexes and disturbed collagen architecture in the corneal extracellular matrix of mucopolysaccharidosis type VII (Sly syndrome).

Young RD, Liskova P, Pinali C, Palka BP, Palos M, Jirsova K, Hrdlickova E, Tesarova M, Elleder M, Zeman J, Meek KM, Knupp C, Quantock AJ.

Invest Ophthalmol Vis Sci. 2011 Aug 24;52(9):6720-8. doi: 10.1167/iovs.11-7377.

PMID:
21743015
37.

Imaging three-dimensional tissue architectures by focused ion beam scanning electron microscopy.

Bushby AJ, P'ng KM, Young RD, Pinali C, Knupp C, Quantock AJ.

Nat Protoc. 2011 Jun;6(6):845-58. doi: 10.1038/nprot.2011.332. Epub 2011 May 26.

PMID:
21637203
38.

Electron tomography reveals multiple self-association of chondroitin sulphate/dermatan sulphate proteoglycans in Chst5-null mouse corneas.

Parfitt GJ, Pinali C, Akama TO, Young RD, Nishida K, Quantock AJ, Knupp C.

J Struct Biol. 2011 Jun;174(3):536-41. doi: 10.1016/j.jsb.2011.03.015. Epub 2011 Apr 1.

PMID:
21440637
39.

Transparent, tough collagen laminates prepared by oriented flow casting, multi-cyclic vitrification and chemical cross-linking.

Tanaka Y, Baba K, Duncan TJ, Kubota A, Asahi T, Quantock AJ, Yamato M, Okano T, Nishida K.

Biomaterials. 2011 May;32(13):3358-66. doi: 10.1016/j.biomaterials.2010.11.011. Epub 2011 Feb 5.

PMID:
21296408
40.

Flow-manipulated, crosslinked collagen gels for use as corneal equivalents.

Duncan TJ, Tanaka Y, Shi D, Kubota A, Quantock AJ, Nishida K.

Biomaterials. 2010 Dec;31(34):8996-9005. doi: 10.1016/j.biomaterials.2010.08.042. Epub 2010 Sep 9.

PMID:
20828807
41.

Structural collagen alterations in macular corneal dystrophy occur mainly in the posterior stroma.

Palka BP, Sotozono C, Tanioka H, Akama TO, Yagi N, Boote C, Young RD, Meek KM, Kinoshita S, Quantock AJ.

Curr Eye Res. 2010 Jul;35(7):580-6. doi: 10.3109/02713681003760150.

PMID:
20597644
42.

Anisotropic mechanical properties of collagen hydrogels induced by uniaxial-flow for ocular applications.

Tanaka Y, Kubota A, Matsusaki M, Duncan T, Hatakeyama Y, Fukuyama K, Quantock AJ, Yamato M, Akashi M, Nishida K.

J Biomater Sci Polym Ed. 2011;22(11):1427-42. doi: 10.1163/092050610X510542. Epub 2010 Jun 30.

PMID:
20594419
43.

Structural and biochemical aspects of keratan sulphate in the cornea.

Quantock AJ, Young RD, Akama TO.

Cell Mol Life Sci. 2010 Mar;67(6):891-906. doi: 10.1007/s00018-009-0228-7. Review.

PMID:
20213925
44.

Structural interactions between collagen and proteoglycans are elucidated by three-dimensional electron tomography of bovine cornea.

Lewis PN, Pinali C, Young RD, Meek KM, Quantock AJ, Knupp C.

Structure. 2010 Feb 10;18(2):239-45. doi: 10.1016/j.str.2009.11.013.

45.

Three-dimensional reconstruction of collagen-proteoglycan interactions in the mouse corneal stroma by electron tomography.

Parfitt GJ, Pinali C, Young RD, Quantock AJ, Knupp C.

J Struct Biol. 2010 May;170(2):392-7. doi: 10.1016/j.jsb.2010.01.019. Epub 2010 Feb 2.

PMID:
20132890
46.

Collagen and mature elastic fibre organisation as a function of depth in the human cornea and limbus.

Kamma-Lorger CS, Boote C, Hayes S, Moger J, Burghammer M, Knupp C, Quantock AJ, Sorensen T, Di Cola E, White N, Young RD, Meek KM.

J Struct Biol. 2010 Mar;169(3):424-30. doi: 10.1016/j.jsb.2009.11.004. Epub 2009 Nov 13.

PMID:
19914381
47.

Differential relative sulfation of Keratan sulfate glycosaminoglycan in the chick cornea during embryonic development.

Liles M, Palka BP, Harris A, Kerr B, Hughes C, Young RD, Meek KM, Caterson B, Quantock AJ.

Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1365-72. doi: 10.1167/iovs.09-4004. Epub 2009 Oct 8.

PMID:
19815728
48.

Stromal edema in klf4 conditional null mouse cornea is associated with altered collagen fibril organization and reduced proteoglycans.

Young RD, Swamynathan SK, Boote C, Mann M, Quantock AJ, Piatigorsky J, Funderburgh JL, Meek KM.

Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4155-61. doi: 10.1167/iovs.09-3561. Epub 2009 Apr 22.

49.

The architecture of the cornea and structural basis of its transparency.

Knupp C, Pinali C, Lewis PN, Parfitt GJ, Young RD, Meek KM, Quantock AJ.

Adv Protein Chem Struct Biol. 2009;78:25-49. doi: 10.1016/S1876-1623(08)78002-7. Epub 2009 Nov 27. Review.

PMID:
20663483
50.

Actin and type I collagen propeptide distribution in the developing chick cornea.

Gealy C, Hayes AJ, Buckwell R, Young RD, Caterson B, Quantock AJ, Ralphs JR.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1653-8. doi: 10.1167/iovs.08-2554. Epub 2008 Dec 13.

PMID:
19074811

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