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Items: 50

1.

Activated Eosinophils Exert Antitumorigenic Activities in Colorectal Cancer.

Reichman H, Itan M, Rozenberg P, Yarmolovski T, Brazowski E, Varol C, Gluck N, Shapira S, Arber N, Qimron U, Karo-Atar D, Lee JJ, Munitz A.

Cancer Immunol Res. 2019 Mar;7(3):388-400. doi: 10.1158/2326-6066.CIR-18-0494. Epub 2019 Jan 21.

PMID:
30665890
2.

Optimizing DNA transduction by selection of mutations that evade bacterial defense systems.

Auster O, Globus R, Yosef I, Qimron U.

RNA Biol. 2018 Sep 13:1-5. doi: 10.1080/15476286.2018.1514235. [Epub ahead of print]

PMID:
30146918
3.

T7 phage factor required for managing RpoS in Escherichia coli.

Tabib-Salazar A, Liu B, Barker D, Burchell L, Qimron U, Matthews SJ, Wigneshweraraj S.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5353-E5362. doi: 10.1073/pnas.1800429115. Epub 2018 May 22.

4.

Crystal-clear memories of a bacterium.

Globus R, Qimron U.

Science. 2017 Sep 15;357(6356):1096-1097. doi: 10.1126/science.aao4929. No abstract available.

PMID:
28912231
5.

Selection of Genetically Modified Bacteriophages Using the CRISPR-Cas System.

Manor M, Qimron U.

Bio Protoc. 2017 Aug 5;7(15). pii: e2431. doi: 10.21769/BioProtoc.2431.

6.

A technological and regulatory outlook on CRISPR crop editing.

Globus R, Qimron U.

J Cell Biochem. 2018 Feb;119(2):1291-1298. doi: 10.1002/jcb.26303. Epub 2017 Aug 28. Review.

PMID:
28731201
7.

CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production.

Rozenberg P, Reichman H, Zab-Bar I, Itan M, Pasmanik-Chor M, Bouffi C, Qimron U, Bachelet I, Fulkerson PC, Rothenberg ME, Munitz A.

Sci Rep. 2017 Jul 19;7(1):5922. doi: 10.1038/s41598-017-06397-4.

8.

Extending the Host Range of Bacteriophage Particles for DNA Transduction.

Yosef I, Goren MG, Globus R, Molshanski-Mor S, Qimron U.

Mol Cell. 2017 Jun 1;66(5):721-728.e3. doi: 10.1016/j.molcel.2017.04.025. Epub 2017 May 25.

9.

Full shut-off of Escherichia coli RNA-polymerase by T7 phage requires a small phage-encoded DNA-binding protein.

Tabib-Salazar A, Liu B, Shadrin A, Burchell L, Wang Z, Wang Z, Goren MG, Yosef I, Qimron U, Severinov K, Matthews SJ, Wigneshweraraj S.

Nucleic Acids Res. 2017 Jul 27;45(13):7697-7707. doi: 10.1093/nar/gkx370.

10.

Sensitizing pathogens to antibiotics using the CRISPR-Cas system.

Goren M, Yosef I, Qimron U.

Drug Resist Updat. 2017 Jan;30:1-6. doi: 10.1016/j.drup.2016.11.001. Epub 2016 Nov 27. Review.

PMID:
28363331
11.

Repeat Size Determination by Two Molecular Rulers in the Type I-E CRISPR Array.

Goren MG, Doron S, Globus R, Amitai G, Sorek R, Qimron U.

Cell Rep. 2016 Sep 13;16(11):2811-2818. doi: 10.1016/j.celrep.2016.08.043.

12.

Natural selection underlies apparent stress-induced mutagenesis in a bacteriophage infection model.

Yosef I, Edgar R, Levy A, Amitai G, Sorek R, Munitz A, Qimron U.

Nat Microbiol. 2016 Apr 18;1(6):16047. doi: 10.1038/nmicrobiol.2016.47.

13.

Counteracting selection for antibiotic-resistant bacteria.

Yosef I, Manor M, Qimron U.

Bacteriophage. 2016 Mar 7;6(1):e1096996. eCollection 2016 Jan-Mar.

14.

Phenotypic heterogeneity in a bacteriophage population only appears as stress-induced mutagenesis.

Yosef I, Edgar R, Qimron U.

Curr Genet. 2016 Nov;62(4):771-773. Epub 2016 Apr 28. Review.

PMID:
27126384
15.

Adaptation in CRISPR-Cas Systems.

Sternberg SH, Richter H, Charpentier E, Qimron U.

Mol Cell. 2016 Mar 17;61(6):797-808. doi: 10.1016/j.molcel.2016.01.030. Epub 2016 Mar 3. Review.

16.

Programming Bacteriophages by Swapping Their Specificity Determinants.

Goren MG, Yosef I, Qimron U.

Trends Microbiol. 2015 Dec;23(12):744-746. doi: 10.1016/j.tim.2015.10.006. Epub 2015 Oct 29.

PMID:
26526502
17.

Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria.

Yosef I, Manor M, Kiro R, Qimron U.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7267-72. doi: 10.1073/pnas.1500107112. Epub 2015 May 18.

18.

Using the CRISPR-Cas System to Positively Select Mutants in Genes Essential for Its Function.

Yosef I, Goren MG, Edgar R, Qimron U.

Methods Mol Biol. 2015;1311:233-50. doi: 10.1007/978-1-4939-2687-9_15.

PMID:
25981477
19.

CRISPR adaptation biases explain preference for acquisition of foreign DNA.

Levy A, Goren MG, Yosef I, Auster O, Manor M, Amitai G, Edgar R, Qimron U, Sorek R.

Nature. 2015 Apr 23;520(7548):505-510. doi: 10.1038/nature14302. Epub 2015 Apr 13.

20.

Microbiology: How bacteria get spacers from invaders.

Yosef I, Qimron U.

Nature. 2015 Mar 12;519(7542):166-7. doi: 10.1038/nature14204. Epub 2015 Feb 18. No abstract available.

PMID:
25707799
21.

Revealing bacterial targets of growth inhibitors encoded by bacteriophage T7.

Molshanski-Mor S, Yosef I, Kiro R, Edgar R, Manor M, Gershovits M, Laserson M, Pupko T, Qimron U.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18715-20. doi: 10.1073/pnas.1413271112. Epub 2014 Dec 15.

22.

Different approaches for using bacteriophages against antibiotic-resistant bacteria.

Yosef I, Kiro R, Molshanski-Mor S, Edgar R, Qimron U.

Bacteriophage. 2014 Jan 1;4(1):e28491. Epub 2014 Mar 11.

23.

Efficient engineering of a bacteriophage genome using the type I-E CRISPR-Cas system.

Kiro R, Shitrit D, Qimron U.

RNA Biol. 2014;11(1):42-4. doi: 10.4161/rna.27766. Epub 2014 Jan 22.

24.

CRISPR adaptation in Escherichia coli subtypeI-E system.

Kiro R, Goren MG, Yosef I, Qimron U.

Biochem Soc Trans. 2013 Dec;41(6):1412-5. doi: 10.1042/BST20130109. Review.

PMID:
24256229
25.

Gene product 0.4 increases bacteriophage T7 competitiveness by inhibiting host cell division.

Kiro R, Molshanski-Mor S, Yosef I, Milam SL, Erickson HP, Qimron U.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19549-54. doi: 10.1073/pnas.1314096110. Epub 2013 Nov 11.

26.

DNA motifs determining the efficiency of adaptation into the Escherichia coli CRISPR array.

Yosef I, Shitrit D, Goren MG, Burstein D, Pupko T, Qimron U.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14396-401. doi: 10.1073/pnas.1300108110. Epub 2013 Aug 12.

27.

Discovery of functional toxin/antitoxin systems in bacteria by shotgun cloning.

Sberro H, Leavitt A, Kiro R, Koh E, Peleg Y, Qimron U, Sorek R.

Mol Cell. 2013 Apr 11;50(1):136-48. doi: 10.1016/j.molcel.2013.02.002. Epub 2013 Mar 7.

28.

Experimental definition of a clustered regularly interspaced short palindromic duplicon in Escherichia coli.

Goren MG, Yosef I, Auster O, Qimron U.

J Mol Biol. 2012 Oct 12;423(1):14-6. doi: 10.1016/j.jmb.2012.06.037. Epub 2012 Jul 3.

PMID:
22771574
29.

The bacterial CRISPR/Cas system as analog of the mammalian adaptive immune system.

Goren M, Yosef I, Edgar R, Qimron U.

RNA Biol. 2012 May;9(5):549-54. doi: 10.4161/rna.20177. Epub 2012 May 1.

PMID:
22614830
30.

Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli.

Yosef I, Goren MG, Qimron U.

Nucleic Acids Res. 2012 Jul;40(12):5569-76. doi: 10.1093/nar/gks216. Epub 2012 Mar 8.

31.

High-temperature protein G is essential for activity of the Escherichia coli clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system.

Yosef I, Goren MG, Kiro R, Edgar R, Qimron U.

Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20136-41. doi: 10.1073/pnas.1113519108. Epub 2011 Nov 23.

32.

Reversing bacterial resistance to antibiotics by phage-mediated delivery of dominant sensitive genes.

Edgar R, Friedman N, Molshanski-Mor S, Qimron U.

Appl Environ Microbiol. 2012 Feb;78(3):744-51. doi: 10.1128/AEM.05741-11. Epub 2011 Nov 23.

33.

The Escherichia coli CRISPR system protects from λ lysogenization, lysogens, and prophage induction.

Edgar R, Qimron U.

J Bacteriol. 2010 Dec;192(23):6291-4. doi: 10.1128/JB.00644-10. Epub 2010 Oct 1.

34.

Mutations in the gene 5 DNA polymerase of bacteriophage T7 suppress the dominant lethal phenotype of gene 2.5 ssDNA binding protein lacking the C-terminal phenylalanine.

Marintcheva B, Qimron U, Yu Y, Tabor S, Richardson CC.

Mol Microbiol. 2009 May;72(4):869-80. doi: 10.1111/j.1365-2958.2009.06682.x. Epub 2009 Mar 30. Erratum in: Mol Microbiol. 2009 Jul;73(2):323. Richardson, Charles [corrected to Richardson, Charles C].

35.

Gene 1.7 of bacteriophage T7 confers sensitivity of phage growth to dideoxythymidine.

Tran NQ, Rezende LF, Qimron U, Richardson CC, Tabor S.

Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9373-8. doi: 10.1073/pnas.0804164105. Epub 2008 Jul 1.

36.

Communication between subunits critical to DNA binding by hexameric helicase of bacteriophage T7.

Lee SJ, Qimron U, Richardson CC.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8908-13. doi: 10.1073/pnas.0802732105. Epub 2008 Jun 23.

37.

Inadequate inhibition of host RNA polymerase restricts T7 bacteriophage growth on hosts overexpressing udk.

Qimron U, Kulczyk AW, Hamdan SM, Tabor S, Richardson CC.

Mol Microbiol. 2008 Jan;67(2):448-57. Epub 2007 Dec 5.

38.

Dynamic DNA helicase-DNA polymerase interactions assure processive replication fork movement.

Hamdan SM, Johnson DE, Tanner NA, Lee JB, Qimron U, Tabor S, van Oijen AM, Richardson CC.

Mol Cell. 2007 Aug 17;27(4):539-49.

39.

Genomewide screens for Escherichia coli genes affecting growth of T7 bacteriophage.

Qimron U, Marintcheva B, Tabor S, Richardson CC.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19039-44. Epub 2006 Nov 29.

40.

Oligomeric states of bacteriophage T7 gene 4 primase/helicase.

Crampton DJ, Ohi M, Qimron U, Walz T, Richardson CC.

J Mol Biol. 2006 Jul 14;360(3):667-77. Epub 2006 May 30.

PMID:
16777142
41.

Primer initiation and extension by T7 DNA primase.

Qimron U, Lee SJ, Hamdan SM, Richardson CC.

EMBO J. 2006 May 17;25(10):2199-208. Epub 2006 Apr 27.

42.

Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1.

Gazit R, Gruda R, Elboim M, Arnon TI, Katz G, Achdout H, Hanna J, Qimron U, Landau G, Greenbaum E, Zakay-Rones Z, Porgador A, Mandelboim O.

Nat Immunol. 2006 May;7(5):517-23. Epub 2006 Mar 26.

PMID:
16565719
43.
44.

Restoration of gene function by homologous recombination: from PCR to gene expression in one step.

Yosef I, Bloushtain N, Shapira M, Qimron U.

Appl Environ Microbiol. 2004 Dec;70(12):7156-60.

45.

Identification of Salmonella typhimurium genes responsible for interference with peptide presentation on MHC class I molecules: Deltayej Salmonella mutants induce superior CD8+ T-cell responses.

Qimron U, Madar N, Mittrücker HW, Zilka A, Yosef I, Bloushtain N, Kaufmann SH, Rosenshine I, Apte RN, Porgador A.

Cell Microbiol. 2004 Nov;6(11):1057-70.

PMID:
15469434
46.

Membrane-associated heparan sulfate proteoglycans are involved in the recognition of cellular targets by NKp30 and NKp46.

Bloushtain N, Qimron U, Bar-Ilan A, Hershkovitz O, Gazit R, Fima E, Korc M, Vlodavsky I, Bovin NV, Porgador A.

J Immunol. 2004 Aug 15;173(4):2392-401.

47.

Non-replicating mucosal and systemic vaccines: quantitative and qualitative differences in the Ag-specific CD8(+) T cell population in different tissues.

Qimron U, Paul L, Bar-Haim E, Bloushtain N, Eisenbach L, Staats HF, Porgador A.

Vaccine. 2004 Mar 29;22(11-12):1390-4.

PMID:
15063561
48.

Role of a conserved arginine in the mechanism of acetohydroxyacid synthase: catalysis of condensation with a specific ketoacid substrate.

Engel S, Vyazmensky M, Vinogradov M, Berkovich D, Bar-Ilan A, Qimron U, Rosiansky Y, Barak Z, Chipman DM.

J Biol Chem. 2004 Jun 4;279(23):24803-12. Epub 2004 Mar 25.

49.

The mechanisms controlling NK cell autoreactivity in TAP2-deficient patients.

Markel G, Mussaffi H, Ling KL, Salio M, Gadola S, Steuer G, Blau H, Achdout H, de Miguel M, Gonen-Gross T, Hanna J, Arnon TI, Qimron U, Volovitz I, Eisenbach L, Blumberg RS, Porgador A, Cerundolo V, Mandelboim O.

Blood. 2004 Mar 1;103(5):1770-8. Epub 2003 Nov 6. Erratum in: Blood. 2015 Mar 19;125(12):2006.

50.

Reliable determination of transposon insertion site in prokaryotes by direct sequencing.

Qimron U, Madar N, Ascarelli-Goell R, Elgrably-Weiss M, Altuvia S, Porgador A.

J Microbiol Methods. 2003 Jul;54(1):137-40.

PMID:
12732433

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