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Items: 27

1.

Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6.

Jang S, Cook NJ, Pye VE, Bedwell GJ, Dudek AM, Singh PK, Cherepanov P, Engelman AN.

Nucleic Acids Res. 2019 May 21;47(9):4663-4683. doi: 10.1093/nar/gkz206.

2.

POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication.

Bellelli R, Belan O, Pye VE, Clement C, Maslen SL, Skehel JM, Cherepanov P, Almouzni G, Boulton SJ.

Mol Cell. 2018 Oct 4;72(1):112-126.e5. doi: 10.1016/j.molcel.2018.08.043. Epub 2018 Sep 11.

3.

Cryo-EM structure of a licensed DNA replication origin.

Abid Ali F, Douglas ME, Locke J, Pye VE, Nans A, Diffley JFX, Costa A.

Nat Commun. 2017 Dec 21;8(1):2241. doi: 10.1038/s41467-017-02389-0.

4.

Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors.

Zhao XZ, Smith SJ, Maskell DP, Métifiot M, Pye VE, Fesen K, Marchand C, Pommier Y, Cherepanov P, Hughes SH, Burke TR Jr.

J Med Chem. 2017 Sep 14;60(17):7315-7332. doi: 10.1021/acs.jmedchem.7b00596. Epub 2017 Aug 10.

5.

Cdt1 stabilizes an open MCM ring for helicase loading.

Frigola J, He J, Kinkelin K, Pye VE, Renault L, Douglas ME, Remus D, Cherepanov P, Costa A, Diffley JFX.

Nat Commun. 2017 Jun 23;8:15720. doi: 10.1038/ncomms15720.

6.

Structural basis for spumavirus GAG tethering to chromatin.

Lesbats P, Serrao E, Maskell DP, Pye VE, O'Reilly N, Lindemann D, Engelman AN, Cherepanov P.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):5509-5514. doi: 10.1073/pnas.1621159114. Epub 2017 May 10.

7.

A supramolecular assembly mediates lentiviral DNA integration.

Ballandras-Colas A, Maskell DP, Serrao E, Locke J, Swuec P, Jónsson SR, Kotecha A, Cook NJ, Pye VE, Taylor IA, Andrésdóttir V, Engelman AN, Costa A, Cherepanov P.

Science. 2017 Jan 6;355(6320):93-95. doi: 10.1126/science.aah7002.

8.

HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant Mutant Integrases.

Zhao XZ, Smith SJ, Maskell DP, Metifiot M, Pye VE, Fesen K, Marchand C, Pommier Y, Cherepanov P, Hughes SH, Burke TR Jr.

ACS Chem Biol. 2016 Apr 15;11(4):1074-81. doi: 10.1021/acschembio.5b00948. Epub 2016 Feb 5.

9.

Experimental phasing for structure determination using membrane-protein crystals grown by the lipid cubic phase method.

Li D, Pye VE, Caffrey M.

Acta Crystallogr D Biol Crystallogr. 2015 Jan 1;71(Pt 1):104-22. doi: 10.1107/S1399004714010360. Epub 2015 Jan 1.

10.

A conformational landscape for alginate secretion across the outer membrane of Pseudomonas aeruginosa.

Tan J, Rouse SL, Li D, Pye VE, Vogeley L, Brinth AR, El Arnaout T, Whitney JC, Howell PL, Sansom MS, Caffrey M.

Acta Crystallogr D Biol Crystallogr. 2014 Aug;70(Pt 8):2054-68. doi: 10.1107/S1399004714001850. Epub 2014 Jul 25.

11.

Structural basis for nuclear import of splicing factors by human Transportin 3.

Maertens GN, Cook NJ, Wang W, Hare S, Gupta SS, Öztop I, Lee K, Pye VE, Cosnefroy O, Snijders AP, KewalRamani VN, Fassati A, Engelman A, Cherepanov P.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2728-33. doi: 10.1073/pnas.1320755111. Epub 2014 Jan 21.

12.

The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry.

Jürgens MC, Vörös J, Rautureau GJ, Shepherd DA, Pye VE, Muldoon J, Johnson CM, Ashcroft AE, Freund SM, Ferguson N.

Nat Chem Biol. 2013 Sep;9(9):540-7. doi: 10.1038/nchembio.1294. Epub 2013 Jul 14.

PMID:
23851574
13.

Crystal structure of the integral membrane diacylglycerol kinase.

Li D, Lyons JA, Pye VE, Vogeley L, Aragão D, Kenyon CP, Shah ST, Doherty C, Aherne M, Caffrey M.

Nature. 2013 May 23;497(7450):521-4. doi: 10.1038/nature12179. Epub 2013 May 15.

14.

Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis.

Lekomtsev S, Su KC, Pye VE, Blight K, Sundaramoorthy S, Takaki T, Collinson LM, Cherepanov P, Divecha N, Petronczki M.

Nature. 2012 Dec 13;492(7428):276-9. doi: 10.1038/nature11773.

PMID:
23235882
15.

Five-year analysis of operative mortality and neonatal outcomes in congenital heart disease.

Padley JR, Cole AD, Pye VE, Chard RB, Nicholson IA, Jacobe S, Baines D, Badawi N, Walker K, Scarfe G, Leclair K, Sholler GF, Winlaw DS.

Heart Lung Circ. 2011 Jul;20(7):460-7. doi: 10.1016/j.hlc.2011.03.009. Epub 2011 Apr 21.

PMID:
21514216
16.

Fetal and post-natal diagnosis of major congenital heart disease: implications for medical and psychological care in the current era.

Sholler GF, Kasparian NA, Pye VE, Cole AD, Winlaw DS.

J Paediatr Child Health. 2011 Oct;47(10):717-22. doi: 10.1111/j.1440-1754.2011.02039.x. Epub 2011 Mar 30.

PMID:
21449901
17.

Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component.

Mikolajek H, Kolstoe SE, Pye VE, Mangione P, Pepys MB, Wood SP.

J Mol Recognit. 2011 Mar-Apr;24(2):371-7. doi: 10.1002/jmr.1090.

PMID:
21360619
18.

Peroxisomal plant 3-ketoacyl-CoA thiolase structure and activity are regulated by a sensitive redox switch.

Pye VE, Christensen CE, Dyer JH, Arent S, Henriksen A.

J Biol Chem. 2010 Jul 30;285(31):24078-88. doi: 10.1074/jbc.M110.106013. Epub 2010 May 12.

19.

The multifunctional protein in peroxisomal beta-oxidation: structure and substrate specificity of the Arabidopsis thaliana protein MFP2.

Arent S, Christensen CE, Pye VE, Nørgaard A, Henriksen A.

J Biol Chem. 2010 Jul 30;285(31):24066-77. doi: 10.1074/jbc.M110.106005. Epub 2010 May 12.

20.

Structure and function of plant acyl-CoA oxidases.

Arent S, Pye VE, Henriksen A.

Plant Physiol Biochem. 2008 Mar;46(3):292-301. doi: 10.1016/j.plaphy.2007.12.014. Epub 2008 Jan 3. Review.

PMID:
18272379
21.

Detailed structural insights into the p97-Npl4-Ufd1 interface.

Isaacson RL, Pye VE, Simpson P, Meyer HH, Zhang X, Freemont PS, Matthews S.

J Biol Chem. 2007 Jul 20;282(29):21361-9. Epub 2007 May 9.

22.

Structural insights into the p97-Ufd1-Npl4 complex.

Pye VE, Beuron F, Keetch CA, McKeown C, Robinson CV, Meyer HH, Zhang X, Freemont PS.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):467-72. Epub 2007 Jan 3.

23.

Going through the motions: the ATPase cycle of p97.

Pye VE, Dreveny I, Briggs LC, Sands C, Beuron F, Zhang X, Freemont PS.

J Struct Biol. 2006 Oct;156(1):12-28. Epub 2006 Mar 29.

PMID:
16621604
24.

Conformational changes in the AAA ATPase p97-p47 adaptor complex.

Beuron F, Dreveny I, Yuan X, Pye VE, McKeown C, Briggs LC, Cliff MJ, Kaneko Y, Wallis R, Isaacson RL, Ladbury JE, Matthews SJ, Kondo H, Zhang X, Freemont PS.

EMBO J. 2006 May 3;25(9):1967-76. Epub 2006 Apr 6.

25.

p97 and close encounters of every kind: a brief review.

Dreveny I, Pye VE, Beuron F, Briggs LC, Isaacson RL, Matthews SJ, McKeown C, Yuan X, Zhang X, Freemont PS.

Biochem Soc Trans. 2004 Nov;32(Pt 5):715-20. Review.

PMID:
15493996
26.

The structure and mechanism of serine acetyltransferase from Escherichia coli.

Pye VE, Tingey AP, Robson RL, Moody PC.

J Biol Chem. 2004 Sep 24;279(39):40729-36. Epub 2004 Jul 1.

27.

The crystal structure of murine p97/VCP at 3.6A.

Huyton T, Pye VE, Briggs LC, Flynn TC, Beuron F, Kondo H, Ma J, Zhang X, Freemont PS.

J Struct Biol. 2003 Dec;144(3):337-48.

PMID:
14643202

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