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Items: 17


Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis.

Pyaram K, Kumar A, Kim YH, Noel S, Reddy SP, Rabb H, Chang CH.

Cell Rep. 2019 Apr 16;27(3):699-707.e4. doi: 10.1016/j.celrep.2019.03.052.


Enhanced oxidative phosphorylation in NKT cells is essential for their survival and function.

Kumar A, Pyaram K, Yarosz EL, Hong H, Lyssiotis CA, Giri S, Chang CH.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7439-7448. doi: 10.1073/pnas.1901376116. Epub 2019 Mar 25.


Advances in NKT cell Immunotherapy for Glioblastoma.

Pyaram K, Yadav VN.

J Cancer Sci Ther. 2018;10(6). pii: 533. doi: 10.4172/1948-5956.1000533. Epub 2018 Jun 18.


PLZF-expressing CD4 T cells show the characteristics of terminally differentiated effector memory CD4 T cells in humans.

Kim YH, Zhu L, Pyaram K, Lopez C, Ohye RG, Garcia JV, Green GE, Chang CH.

Eur J Immunol. 2018 Jul;48(7):1255-1257. doi: 10.1002/eji.201747426. Epub 2018 Apr 30.


Reactive Oxygen Species Regulate the Inflammatory Function of NKT Cells through Promyelocytic Leukemia Zinc Finger.

Kim YH, Kumar A, Chang CH, Pyaram K.

J Immunol. 2017 Nov 15;199(10):3478-3487. doi: 10.4049/jimmunol.1700567. Epub 2017 Oct 11.


Thymic NF-κB-inducing kinase regulates CD4+ T cell-elicited liver injury and fibrosis in mice.

Shen H, Sheng L, Xiong Y, Kim YH, Jiang L, Chen Z, Liu Y, Pyaram K, Chang CH, Rui L.

J Hepatol. 2017 Jul;67(1):100-109. doi: 10.1016/j.jhep.2017.02.025. Epub 2017 Mar 6.


Temporal regulation of Wnt/β-catenin signaling is important for invariant NKT cell development and terminal maturation.

Pyaram K, Sen JM, Chang CH.

Mol Immunol. 2017 May;85:47-56. doi: 10.1016/j.molimm.2017.01.025. Epub 2017 Feb 14.


β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation.

Berga-Bolaños R, Sharma A, Steinke FC, Pyaram K, Kim YH, Sultana DA, Fang JX, Chang CH, Xue HH, Heller NM, Sen JM.

BMC Immunol. 2015 Oct 19;16:62. doi: 10.1186/s12865-015-0121-0.


DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates.

Shin J, Maekawa T, Abe T, Hajishengallis E, Hosur K, Pyaram K, Mitroulis I, Chavakis T, Hajishengallis G.

Sci Transl Med. 2015 Sep 30;7(307):307ra155. doi: 10.1126/scitranslmed.aac5380.


Mammalian target of rapamycin complex 2 regulates invariant NKT cell development and function independent of promyelocytic leukemia zinc-finger.

Prevot N, Pyaram K, Bischoff E, Sen JM, Powell JD, Chang CH.

J Immunol. 2015 Jan 1;194(1):223-30. doi: 10.4049/jimmunol.1401985. Epub 2014 Nov 17.


Expression and function of the homeostatic molecule Del-1 in endothelial cells and the periodontal tissue.

Shin J, Hosur KB, Pyaram K, Jotwani R, Liang S, Chavakis T, Hajishengallis G.

Clin Dev Immunol. 2013;2013:617809. doi: 10.1155/2013/617809. Epub 2013 Dec 12.


Species selectivity in poxviral complement regulators is dictated by the charge reversal in the central complement control protein modules.

Yadav VN, Pyaram K, Ahmad M, Sahu A.

J Immunol. 2012 Aug 1;189(3):1431-9. doi: 10.4049/jimmunol.1200946. Epub 2012 Jun 25.


Domain swapping reveals complement control protein modules critical for imparting cofactor and decay-accelerating activities in vaccinia virus complement control protein.

Ahmad M, Raut S, Pyaram K, Kamble A, Mullick J, Sahu A.

J Immunol. 2010 Nov 15;185(10):6128-37. doi: 10.4049/jimmunol.1001617. Epub 2010 Oct 18.


Influence of electrostatics on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus.

Pyaram K, Kieslich CA, Yadav VN, Morikis D, Sahu A.

J Immunol. 2010 Feb 15;184(4):1956-67. doi: 10.4049/jimmunol.0903261. Epub 2010 Jan 20.


Viral complement regulators: the expert mimicking swindlers.

Ahmad M, Pyaram K, Mullick J, Sahu A.

Indian J Biochem Biophys. 2007 Oct;44(5):331-43. Review.


Identification of hot spots in the variola virus complement inhibitor (SPICE) for human complement regulation.

Yadav VN, Pyaram K, Mullick J, Sahu A.

J Virol. 2008 Apr;82(7):3283-94. doi: 10.1128/JVI.01935-07. Epub 2008 Jan 23.

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