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Items: 1 to 50 of 73

1.

Inadequate socialisation, inactivity, and urban living environment are associated with social fearfulness in pet dogs.

Puurunen J, Hakanen E, Salonen MK, Mikkola S, Sulkama S, Araujo C, Lohi H.

Sci Rep. 2020 Feb 26;10(1):3527. doi: 10.1038/s41598-020-60546-w.

PMID:
32103117
2.

Fearful dogs have increased plasma glutamine and γ-glutamyl glutamine.

Puurunen J, Tiira K, Vapalahti K, Lehtonen M, Hanhineva K, Lohi H.

Sci Rep. 2018 Oct 29;8(1):15976. doi: 10.1038/s41598-018-34321-x.

3.

The prevalence of Type 2 diabetes is not increased in normal-weight women with PCOS.

Pelanis R, Mellembakken JR, Sundström-Poromaa I, Ravn P, Morin-Papunen L, Tapanainen JS, Piltonen T, Puurunen J, Hirschberg AL, Fedorcsak P, Andersen M, Glintborg D.

Hum Reprod. 2017 Nov 1;32(11):2279-2286. doi: 10.1093/humrep/dex294.

PMID:
29040530
4.

Bone markers in polycystic ovary syndrome: A multicentre study.

Lingaiah S, Morin-Papunen L, Piltonen T, Puurunen J, Sundström-Poromaa I, Stener-Victorin E, Bloigu R, Risteli J, Tapanainen JS.

Clin Endocrinol (Oxf). 2017 Dec;87(6):673-679. doi: 10.1111/cen.13456. Epub 2017 Sep 21.

PMID:
28845895
5.

Testosterone is associated with insulin resistance index independently of adiposity in women with polycystic ovary syndrome.

Luotola K, Piltonen TT, Puurunen J, Morin-Papunen LC, Tapanainen JS.

Gynecol Endocrinol. 2018 Jan;34(1):40-44. doi: 10.1080/09513590.2017.1342793. Epub 2017 Jul 5.

PMID:
28678568
6.

Racial and ethnic differences in the prevalence of metabolic syndrome and its components of metabolic syndrome in women with polycystic ovary syndrome: a regional cross-sectional study.

Chan JL, Kar S, Vanky E, Morin-Papunen L, Piltonen T, Puurunen J, Tapanainen JS, Maciel GAR, Hayashida SAY, Soares JM Jr, Baracat EC, Mellembakken JR, Dokras A.

Am J Obstet Gynecol. 2017 Aug;217(2):189.e1-189.e8. doi: 10.1016/j.ajog.2017.04.007. Epub 2017 Apr 8.

PMID:
28400308
7.

Normo- and hyperandrogenic women with polycystic ovary syndrome exhibit an adverse metabolic profile through life.

Pinola P, Puukka K, Piltonen TT, Puurunen J, Vanky E, Sundström-Poromaa I, Stener-Victorin E, Lindén Hirschberg A, Ravn P, Skovsager Andersen M, Glintborg D, Mellembakken JR, Ruokonen A, Tapanainen JS, Morin-Papunen LC.

Fertil Steril. 2017 Mar;107(3):788-795.e2. doi: 10.1016/j.fertnstert.2016.12.017. Epub 2017 Jan 12.

PMID:
28089571
8.

A non-targeted metabolite profiling pilot study suggests that tryptophan and lipid metabolisms are linked with ADHD-like behaviours in dogs.

Puurunen J, Sulkama S, Tiira K, Araujo C, Lehtonen M, Hanhineva K, Lohi H.

Behav Brain Funct. 2016 Sep 29;12(1):27.

9.

Should we individualize lipid profiling in women with polycystic ovary syndrome?

Sundström Poromaa I, Mellembakken JR, Morin-Papunen L, Piltonen T, Puurunen J, Tapanainen JS, Stener-Victorin E, Hirschberg AL, Vanky E, Ravn P, Glintborg D, Andersen M.

Hum Reprod. 2016 Dec;31(12):2791-2795. Epub 2016 Sep 22. Erratum in: Hum Reprod. 2017 Apr 1;32(4):966.

PMID:
27664213
10.

IL-1 receptor antagonist levels are associated with glucose tolerance in polycystic ovary syndrome.

Luotola K, Piltonen TT, Puurunen J, Tapanainen JS.

Clin Endocrinol (Oxf). 2016 Sep;85(3):430-5. doi: 10.1111/cen.13077. Epub 2016 Apr 26.

PMID:
27061312
11.

Non-targeted metabolite profiling reveals changes in oxidative stress, tryptophan and lipid metabolisms in fearful dogs.

Puurunen J, Tiira K, Lehtonen M, Hanhineva K, Lohi H.

Behav Brain Funct. 2016 Feb 12;12(1):7. doi: 10.1186/s12993-016-0091-2.

12.

Androgen Profile Through Life in Women With Polycystic Ovary Syndrome: A Nordic Multicenter Collaboration Study.

Pinola P, Piltonen TT, Puurunen J, Vanky E, Sundström-Poromaa I, Stener-Victorin E, Ruokonen A, Puukka K, Tapanainen JS, Morin-Papunen LC.

J Clin Endocrinol Metab. 2015 Sep;100(9):3400-7. doi: 10.1210/jc.2015-2123. Epub 2015 Jul 20.

PMID:
26192874
13.

The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity.

Hukkanen J, Puurunen J, Hyötyläinen T, Savolainen MJ, Ruokonen A, Morin-Papunen L, Orešič M, Piltonen T, Tapanainen JS.

Br J Clin Pharmacol. 2015 Sep;80(3):473-9. doi: 10.1111/bcp.12701. Epub 2015 Jul 22.

14.

Statin therapy worsens insulin sensitivity in women with polycystic ovary syndrome (PCOS): a prospective, randomized, double-blind, placebo-controlled study.

Puurunen J, Piltonen T, Puukka K, Ruokonen A, Savolainen MJ, Bloigu R, Morin-Papunen L, Tapanainen JS.

J Clin Endocrinol Metab. 2013 Dec;98(12):4798-807. doi: 10.1210/jc.2013-2674. Epub 2013 Oct 23.

PMID:
24152688
15.

Antimüllerian hormone levels decrease in women using combined contraception independently of administration route.

Kallio S, Puurunen J, Ruokonen A, Vaskivuo T, Piltonen T, Tapanainen JS.

Fertil Steril. 2013 Apr;99(5):1305-10. doi: 10.1016/j.fertnstert.2012.11.034. Epub 2012 Dec 20.

PMID:
23260855
16.

Oral, transdermal and vaginal combined contraceptives induce an increase in markers of chronic inflammation and impair insulin sensitivity in young healthy normal-weight women: a randomized study.

Piltonen T, Puurunen J, Hedberg P, Ruokonen A, Mutt SJ, Herzig KH, Nissinen A, Morin-Papunen L, Tapanainen JS.

Hum Reprod. 2012 Oct;27(10):3046-56. doi: 10.1093/humrep/des225. Epub 2012 Jul 18.

PMID:
22811306
17.

Unfavorable hormonal, metabolic, and inflammatory alterations persist after menopause in women with PCOS.

Puurunen J, Piltonen T, Morin-Papunen L, Perheentupa A, Järvelä I, Ruokonen A, Tapanainen JS.

J Clin Endocrinol Metab. 2011 Jun;96(6):1827-34. doi: 10.1210/jc.2011-0039. Epub 2011 Mar 30.

PMID:
21450988
18.

Adrenal androgen production capacity remains high up to menopause in women with polycystic ovary syndrome.

Puurunen J, Piltonen T, Jaakkola P, Ruokonen A, Morin-Papunen L, Tapanainen JS.

J Clin Endocrinol Metab. 2009 Jun;94(6):1973-8. doi: 10.1210/jc.2008-2583. Epub 2009 Mar 24.

PMID:
19318449
19.

Comparative effects of medetomidine enantiomers on in vitro and in vivo microsomal drug metabolism.

Pelkonen O, Puurunen J, Arvela P, Lammintausta R.

Pharmacol Toxicol. 1991 Sep;69(3):189-94.

PMID:
1686651
20.

Occupational contact allergy to 2,4-diamino-6-chloromethylpteridine hydrochloride: an intermediate product in methotrexate synthesis.

Lahti A, Puurunen J, Hannuksela M.

Contact Dermatitis. 1990 May;22(5):294. No abstract available.

PMID:
2143449
21.
22.

Stimulatory effect of prostaglandin F2 alpha on gastric acid secretion in rats.

Jaatinen T, Puurunen J, Karppanen H.

Pharmacol Toxicol. 1988 Oct;63(4):207-10.

PMID:
3194341
23.

Centrally applied histamine increases gastric acid secretion in rats.

Puurunen J.

Naunyn Schmiedebergs Arch Pharmacol. 1988 Jul;338(1):96-8.

PMID:
3237254
24.

Atrial natriuretic peptide (ANP) in rat gastrointestinal tract.

Vuolteenaho O, Arjamaa O, Vakkuri O, Maksniemi T, Nikkilä L, Kangas J, Puurunen J, Ruskoaho H, Leppäluoto J.

FEBS Lett. 1988 Jun 6;233(1):79-82.

25.

Alpha-1 adrenoceptor-mediated positive inotropic effect and inositol trisphosphate increase in mammalian heart.

Scholz J, Schaefer B, Schmitz W, Scholz H, Steinfath M, Lohse M, Schwabe U, Puurunen J.

J Pharmacol Exp Ther. 1988 Apr;245(1):327-35.

PMID:
2834540
26.

Central gastric antisecretory action of adenosine in the rat.

Puurunen J, Huttunen P.

Eur J Pharmacol. 1988 Feb 16;147(1):59-66.

PMID:
3371411
27.

Stimulation of central alpha-2 adrenoceptors inhibits gastric secretion in rats by releasing vasopressin.

Puurunen J.

Naunyn Schmiedebergs Arch Pharmacol. 1988 Feb;337(2):164-8.

PMID:
2835691
28.

Cardiovascular and sedative alpha-adrenoceptor effects of detomidine-like arylalkyl imidazoles and associated derivatives.

Savola JM, Ruskoaho H, Salonen JS, Puurunen J, Karjalainen A, Kurkela K, Kärki NT.

Arzneimittelforschung. 1988 Jan;38(1):29-35.

PMID:
2835056
29.

Interactions between intracellular cyclic AMP and agonist-induced inositol phospholipid breakdown in isolated gastric mucosal cells of the rat.

Puurunen J, Lohse MJ, Schwabe U.

Naunyn Schmiedebergs Arch Pharmacol. 1987 Nov;336(5):471-7.

PMID:
2830543
31.

Lack of direct effect of adenosine on the parietal cell function in the rat.

Puurunen J, Ruoff HJ, Schwabe U.

Pharmacol Toxicol. 1987 Apr;60(4):315-7. No abstract available.

PMID:
3588529
32.
33.

Pertussis toxin does not inhibit the alpha 1-adrenoceptor-mediated effect on inositol phosphate production in the heart.

Schmitz W, Scholz H, Scholz J, Steinfath M, Lohse M, Puurunen J, Schwabe U.

Eur J Pharmacol. 1987 Feb 24;134(3):377-8. No abstract available.

PMID:
3032660
34.

Evidence for medetomidine as a selective and potent agonist at alpha 2-adrenoreceptors.

Savola JM, Ruskoaho H, Puurunen J, Salonen JS, Kärki NT.

J Auton Pharmacol. 1986 Dec;6(4):275-84.

PMID:
2880852
35.

Re-evaluation of drug-interaction with alpha-adrenoceptors in vivo and in vitro using imidazole derivatives.

Savola JM, Virtanen R, Karjalainen A, Ruskoaho H, Puurunen J, Kärki NT.

Life Sci. 1986 Apr 14;38(15):1409-15.

PMID:
3007911
36.

Vagally mediated stimulation of gastric acid secretion by intravenously administered adenosine derivatives in anaesthetized rats.

Puurunen J, Aittakumpu R, Tanskanen T.

Acta Pharmacol Toxicol (Copenh). 1986 Apr;58(4):265-71.

PMID:
3012943
37.

Cardiovascular action of detomidine, a sedative and analgesic imidazole derivative with alpha-agonistic properties.

Savola JM, Ruskoaho H, Puurunen J, Kärki NT.

Eur J Pharmacol. 1985 Nov 26;118(1-2):69-76.

PMID:
2867913
38.
40.

Usefulness of follow-up liver-function tests after dichloromethane exposure.

Puurunen J, Sotaniemi E.

Lancet. 1985 Apr 6;1(8432):822. No abstract available.

PMID:
2858701
41.
42.

Vagally mediated bradycardiac effect of prazosin in anaesthetized rats.

Paakkari I, Puurunen J.

Eur J Pharmacol. 1984 Oct 15;105(3-4):223-8.

PMID:
6510469
43.

Centrally administered PGE2 inhibits gastric secretion in the rat by releasing vasopressin.

Puurunen J, Leppäluoto J.

Eur J Pharmacol. 1984 Sep 3;104(1-2):145-50.

PMID:
6094207
44.

Protective effect of intracerebroventricularly administered PGE2 on rat gastric mucosa.

Puurunen J.

Acta Pharmacol Toxicol (Copenh). 1984 May;54(5):425-7. No abstract available.

PMID:
6589943
45.

[Prostaglandins and the gastrointestinal tract].

Puurunen J.

Duodecim. 1984;100(16):1034-9. Finnish. No abstract available.

PMID:
6510259
47.
48.

Central inhibitory action of prostaglandin E2 on gastric secretion in the rat.

Puurunen J.

Eur J Pharmacol. 1983 Jul 22;91(2-3):245-9.

PMID:
6578038
49.

Interactions between ethanol and acetylsalicylic acid in damaging the rat gastric mucosa.

Puurunen J, Huttunen P, Hirvonen J.

Acta Pharmacol Toxicol (Copenh). 1983 May;52(5):321-7.

PMID:
6603742
50.

The cardiovascular effects of MPV 295 [4(5)-2-(2,6-dimethylphenyl)ethylimidazole], a new antihypertensive agent with alpha 2-adrenoceptor agonistic properties.

Ruskoaho H, Savola JM, Kaipiainen S, Puurunen J, Kärki N.

Naunyn Schmiedebergs Arch Pharmacol. 1983 May;322(4):279-85. No abstract available.

PMID:
6135165

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