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Items: 9

1.

Calcium affects OX1 orexin (hypocretin) receptor responses by modifying both orexin binding and the signal transduction machinery.

Putula J, Pihlajamaa T, Kukkonen JP.

Br J Pharmacol. 2014 Dec;171(24):5816-28. doi: 10.1111/bph.12883. Epub 2014 Nov 5.

2.

Autocrine endocannabinoid signaling through CB1 receptors potentiates OX1 orexin receptor signaling.

Jäntti MH, Putula J, Turunen PM, Näsman J, Reijonen S, Lindqvist C, Kukkonen JP.

Mol Pharmacol. 2013 Mar;83(3):621-32. doi: 10.1124/mol.112.080523. Epub 2012 Dec 11.

PMID:
23233488
4.

Mapping of the binding sites for the OX1 orexin receptor antagonist, SB-334867, using orexin/hypocretin receptor chimaeras.

Putula J, Kukkonen JP.

Neurosci Lett. 2012 Jan 6;506(1):111-5. doi: 10.1016/j.neulet.2011.10.061. Epub 2011 Nov 2.

PMID:
22079339
5.

Involvement of cyclin-dependent kinase-5 in the kainic acid-mediated degeneration of glutamatergic synapses in the rat hippocampus.

Putkonen N, Kukkonen JP, Mudo G, Putula J, Belluardo N, Lindholm D, Korhonen L.

Eur J Neurosci. 2011 Oct;34(8):1212-21. doi: 10.1111/j.1460-9568.2011.07858.x. Epub 2011 Oct 7.

PMID:
21978141
6.

OX1 orexin/hypocretin receptor activation of phospholipase D.

Jäntti MH, Putula J, Somerharju P, Frohman MA, Kukkonen JP.

Br J Pharmacol. 2012 Feb;165(4b):1109-23. doi: 10.1111/j.1476-5381.2011.01565.x.

7.

Orexin/hypocretin receptor chimaeras reveal structural features important for orexin peptide distinction.

Putula J, Turunen PM, Johansson L, Näsman J, Ra R, Korhonen L, Kukkonen JP.

FEBS Lett. 2011 May 6;585(9):1368-74. doi: 10.1016/j.febslet.2011.04.020. Epub 2011 Apr 15.

8.

Agonist ligand discrimination by the two orexin receptors depends on the expression system.

Putula J, Turunen PM, Jäntti MH, Ekholm ME, Kukkonen JP.

Neurosci Lett. 2011 Apr 20;494(1):57-60. doi: 10.1016/j.neulet.2011.02.055. Epub 2011 Mar 6.

PMID:
21362456
9.

Filtration assay for arachidonic acid release.

Turunen PM, Putula J, Kukkonen JP.

Anal Biochem. 2010 Dec 15;407(2):233-6. doi: 10.1016/j.ab.2010.07.014. Epub 2010 Jul 23.

PMID:
20655865

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