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Items: 28

1.

Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products.

Petrlova J, Petruk G, Huber RG, McBurnie EW, van der Plas MJA, Bond PJ, Puthia M, Schmidtchen A.

J Biol Chem. 2020 Feb 7. pii: jbc.RA120.012741. doi: 10.1074/jbc.RA120.012741. [Epub ahead of print]

2.

A dual-action peptide-containing hydrogel targets wound infection and inflammation.

Puthia M, Butrym M, Petrlova J, Strömdahl AC, Andersson MÅ, Kjellström S, Schmidtchen A.

Sci Transl Med. 2020 Jan 1;12(524). pii: eaax6601. doi: 10.1126/scitranslmed.aax6601.

PMID:
31894104
3.

A novel derivative of the fungal antimicrobial peptide plectasin is active against Mycobacterium tuberculosis.

Tenland E, Krishnan N, Rönnholm A, Kalsum S, Puthia M, Mörgelin M, Davoudi M, Otrocka M, Alaridah N, Glegola-Madejska I, Sturegård E, Schmidtchen A, Lerm M, Robertson BD, Godaly G.

Tuberculosis (Edinb). 2018 Dec;113:231-238. doi: 10.1016/j.tube.2018.10.008. Epub 2018 Oct 30.

4.

Neuroepithelial control of mucosal inflammation in acute cystitis.

Butler DSC, Ambite I, Nagy K, Cafaro C, Ahmed A, Nadeem A, Filenko N, Tran TH, Andersson KE, Wullt B, Puthia M, Svanborg C.

Sci Rep. 2018 Jul 20;8(1):11015. doi: 10.1038/s41598-018-28634-0.

5.

Caspase-1 deficiency reduces eosinophilia and interleukin-33 in an asthma exacerbation model.

Menzel M, Akbarshahi H, Mahmutovic Persson I, Puthia M, Bjermer L, Uller L.

ERJ Open Res. 2017 Oct 16;3(4). pii: 00047-2017. doi: 10.1183/23120541.00047-2017. eCollection 2017 Oct.

6.

Thrombin-derived host defence peptide modulates neutrophil rolling and migration in vitro and functional response in vivo.

Lim CH, Puthia M, Butrym M, Tay HM, Lee MZY, Hou HW, Schmidtchen A.

Sci Rep. 2017 Sep 11;7(1):11201. doi: 10.1038/s41598-017-11464-x.

7.

Mycobacteria Manipulate G-Protein-Coupled Receptors to Increase Mucosal Rac1 Expression in the Lungs.

Alaridah N, Lutay N, Tenland E, Rönnholm A, Hallgren O, Puthia M, Westergren-Thorsson G, Godaly G.

J Innate Immun. 2017;9(3):318-329. doi: 10.1159/000453454. Epub 2016 Dec 24.

8.

Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets.

Ambite I, Puthia M, Nagy K, Cafaro C, Nadeem A, Butler DS, Rydström G, Filenko NA, Wullt B, Miethke T, Svanborg C.

PLoS Pathog. 2016 Oct 12;12(10):e1005848. doi: 10.1371/journal.ppat.1005848. eCollection 2016 Oct.

9.

Susceptibility to Urinary Tract Infection: Benefits and Hazards of the Antibacterial Host Response.

Ambite I, Nagy K, Godaly G, Puthia M, Wullt B, Svanborg C.

Microbiol Spectr. 2016 Jun;4(3). doi: 10.1128/microbiolspec.UTI-0019-2014. Review.

PMID:
27337480
10.

Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation.

Waldhuber A, Puthia M, Wieser A, Cirl C, Dürr S, Neumann-Pfeifer S, Albrecht S, Römmler F, Müller T, Zheng Y, Schubert S, Groß O, Svanborg C, Miethke T.

J Clin Invest. 2016 Jul 1;126(7):2425-36. doi: 10.1172/JCI81916. Epub 2016 May 23.

11.

IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections.

Puthia M, Ambite I, Cafaro C, Butler D, Huang Y, Lutay N, Rydström G, Gullstrand B, Swaminathan B, Nadeem A, Nilsson B, Svanborg C.

Sci Transl Med. 2016 Apr 27;8(336):336ra59. doi: 10.1126/scitranslmed.aaf1156.

PMID:
27122612
12.

Urinary Tract Infection Molecular Mechanisms and Clinical Translation.

Godaly G, Ambite I, Puthia M, Nadeem A, Ho J, Nagy K, Huang Y, Rydström G, Svanborg C.

Pathogens. 2016 Feb 24;5(1). pii: E24. doi: 10.3390/pathogens5010024. Review.

13.

Targeting of nucleotide-binding proteins by HAMLET--a conserved tumor cell death mechanism.

Ho JC, Nadeem A, Rydström A, Puthia M, Svanborg C.

Oncogene. 2016 Feb 18;35(7):897-907. doi: 10.1038/onc.2015.144. Epub 2015 Jun 1.

PMID:
26028028
14.

Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens.

Sheppard NC, Brinckmann SA, Gartlan KH, Puthia M, Svanborg C, Krashias G, Eisenbarth SC, Flavell RA, Sattentau QJ, Wegmann F.

Int Immunol. 2014 Oct;26(10):531-8. doi: 10.1093/intimm/dxu055. Epub 2014 May 20.

PMID:
24844701
15.

The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.

Jaillon S, Moalli F, Ragnarsdottir B, Bonavita E, Puthia M, Riva F, Barbati E, Nebuloni M, Cvetko Krajinovic L, Markotic A, Valentino S, Doni A, Tartari S, Graziani G, Montanelli A, Delneste Y, Svanborg C, Garlanda C, Mantovani A.

Immunity. 2014 Apr 17;40(4):621-32. doi: 10.1016/j.immuni.2014.02.015.

16.

The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response.

He JS, Meyer-Hermann M, Xiangying D, Zuan LY, Jones LA, Ramakrishna L, de Vries VC, Dolpady J, Aina H, Joseph S, Narayanan S, Subramaniam S, Puthia M, Wong G, Xiong H, Poidinger M, Urban JF, Lafaille JJ, Curotto de Lafaille MA.

J Exp Med. 2013 Nov 18;210(12):2755-71. doi: 10.1084/jem.20131539. Epub 2013 Nov 11.

17.

Slit2 prevents neutrophil recruitment and renal ischemia-reperfusion injury.

Chaturvedi S, Yuen DA, Bajwa A, Huang YW, Sokollik C, Huang L, Lam GY, Tole S, Liu GY, Pan J, Chan L, Sokolskyy Y, Puthia M, Godaly G, John R, Wang C, Lee WL, Brumell JH, Okusa MD, Robinson LA.

J Am Soc Nephrol. 2013 Jul;24(8):1274-87. doi: 10.1681/ASN.2012090890. Epub 2013 Jun 13.

18.

Bacterial control of host gene expression through RNA polymerase II.

Lutay N, Ambite I, Grönberg Hernandez J, Rydström G, Ragnarsdóttir B, Puthia M, Nadeem A, Zhang J, Storm P, Dobrindt U, Wullt B, Svanborg C.

J Clin Invest. 2013 Jun;123(6):2366-79.

19.

Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells).

Puthia M, Storm P, Nadeem A, Hsiung S, Svanborg C.

Gut. 2014 Jan;63(1):131-42. doi: 10.1136/gutjnl-2012-303715. Epub 2013 Jan 24.

20.

HAMLET: functional properties and therapeutic potential.

Ho C S J, Rydström A, Trulsson M, Bålfors J, Storm P, Puthia M, Nadeem A, Svanborg C.

Future Oncol. 2012 Oct;8(10):1301-13. doi: 10.2217/fon.12.122. Review.

PMID:
23130929
21.

Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens.

Wegmann F, Gartlan KH, Harandi AM, Brinckmann SA, Coccia M, Hillson WR, Kok WL, Cole S, Ho LP, Lambe T, Puthia M, Svanborg C, Scherer EM, Krashias G, Williams A, Blattman JN, Greenberg PD, Flavell RA, Moghaddam AE, Sheppard NC, Sattentau QJ.

Nat Biotechnol. 2012 Sep;30(9):883-8.

22.

Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis.

Storm P, Aits S, Puthia MK, Urbano A, Northen T, Powers S, Bowen B, Chao Y, Reindl W, Lee DY, Sullivan NL, Zhang J, Trulsson M, Yang H, Watson JD, Svanborg C.

Oncogene. 2011 Dec 1;30(48):4765-79. doi: 10.1038/onc.2011.196. Epub 2011 Jun 6.

23.

The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.

Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M.

J Immunol. 2008 Jun 15;180(12):8333-41.

25.
26.

Protease activity of Blastocystis hominis.

Sio SW, Puthia MK, Lee AS, Lu J, Tan KS.

Parasitol Res. 2006 Jul;99(2):126-30. Epub 2006 Mar 4.

PMID:
16518611
27.

Degradation of human secretory immunoglobulin A by Blastocystis.

Puthia MK, Vaithilingam A, Lu J, Tan KS.

Parasitol Res. 2005 Nov;97(5):386-9. Epub 2005 Sep 7.

PMID:
16151742
28.

Plasmodium falciparum: a simplified technique for obtaining singly infected erythrocytes.

Puthia MK, Tan KS.

Parasitol Res. 2005 Feb;95(3):176-8. Epub 2004 Dec 23.

PMID:
15616858

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