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Items: 1 to 50 of 126

1.

Saliva and Serum Immune Responses in Apical Periodontitis.

Pietiäinen M, Liljestrand JM, Akhi R, Buhlin K, Johansson A, Paju S, Salminen A, Mäntylä P, Sinisalo J, Tjäderhane L, Hörkkö S, Pussinen PJ.

J Clin Med. 2019 Jun 21;8(6). pii: E889. doi: 10.3390/jcm8060889.

2.

Association of Childhood Oral Infections With Cardiovascular Risk Factors and Subclinical Atherosclerosis in Adulthood.

Pussinen PJ, Paju S, Koponen J, Viikari JSA, Taittonen L, Laitinen T, Burgner DP, Kähönen M, Hutri-Kähönen N, Raitakari OT, Juonala M.

JAMA Netw Open. 2019 Apr 5;2(4):e192523. doi: 10.1001/jamanetworkopen.2019.2523.

3.

Salivary IgA to MAA-LDL and Oral Pathogens Are Linked to Coronary Disease.

Akhi R, Wang C, Nissinen AE, Kankaanpää J, Bloigu R, Paju S, Mäntylä P, Buhlin K, Sinisalo J, Pussinen PJ, Hörkkö S.

J Dent Res. 2019 Mar;98(3):296-303. doi: 10.1177/0022034518818445. Epub 2019 Jan 22.

PMID:
30669938
4.

Oral health: a neglected aspect of diabetes care.

Pussinen PJ, Salomaa V.

Lancet Diabetes Endocrinol. 2018 Dec;6(12):917-919. doi: 10.1016/S2213-8587(18)30032-9. Epub 2018 Oct 24. No abstract available.

PMID:
30472991
5.

Smoking confounds the periodontal diagnostics using saliva biomarkers.

Lahdentausta L, Paju S, Mäntylä P, Buhlin K, Pietiäinen M, Tervahartiala T, Nieminen MS, Sinisalo J, Sorsa T, Pussinen PJ.

J Periodontol. 2019 May;90(5):475-483. doi: 10.1002/JPER.18-0545. Epub 2018 Dec 14.

PMID:
30447005
6.

Association between periodontitis and risk of Alzheimer's disease, mild cognitive impairment and subjective cognitive decline: A case-control study.

Holmer J, Eriksdotter M, Schultzberg M, Pussinen PJ, Buhlin K.

J Clin Periodontol. 2018 Nov;45(11):1287-1298. doi: 10.1111/jcpe.13016.

PMID:
30289998
7.

Mediators between oral dysbiosis and cardiovascular diseases.

Pietiäinen M, Liljestrand JM, Kopra E, Pussinen PJ.

Eur J Oral Sci. 2018 Oct;126 Suppl 1:26-36. doi: 10.1111/eos.12423. Review.

PMID:
30178551
8.

Salivary biomarkers in association with periodontal parameters and the periodontitis risk haplotype.

Liukkonen J, Gürsoy UK, Könönen E, Gürsoy M, Metso J, Salminen A, Kopra E, Jauhiainen M, Mäntylä P, Buhlin K, Paju S, Sorsa T, Nieminen MS, Lokki ML, Sinisalo J, Pussinen PJ.

Innate Immun. 2018 Oct;24(7):439-447. doi: 10.1177/1753425918796207. Epub 2018 Sep 3.

PMID:
30176756
9.

Importance of maintaining good oral health in cardiometabolic disorders.

Pussinen PJ, Malle E, Sattler W.

Int J Cardiol. 2018 Nov 15;271:291-292. doi: 10.1016/j.ijcard.2018.07.014. Epub 2018 Jul 4. No abstract available.

PMID:
30001946
10.

Saliva and serum biomarkers in periodontitis and coronary artery disease.

Lahdentausta LSJ, Paju S, Mäntylä P, Buhlin K, Tervahartiala T, Pietiäinen M, Alfthan H, Nieminen MS, Sinisalo J, Sorsa T, Pussinen PJ.

J Clin Periodontol. 2018 Sep;45(9):1045-1055. doi: 10.1111/jcpe.12976. Epub 2018 Aug 16.

PMID:
29972696
11.

Cumulative use of salivary markers with an adaptive design improves detection of periodontal disease over fixed biomarker thresholds.

Gürsoy UK, Pussinen PJ, Salomaa V, Syrjäläinen S, Könönen E.

Acta Odontol Scand. 2018 Oct;76(7):493-496. doi: 10.1080/00016357.2018.1441436. Epub 2018 Feb 20.

PMID:
29463174
12.

Serum matrix metalloproteinase-8, tissue inhibitor of metalloproteinase and myeloperoxidase in ischemic stroke.

Palm F, Pussinen PJ, Safer A, Tervahartiala T, Sorsa T, Urbanek C, Becher H, Grau AJ.

Atherosclerosis. 2018 Apr;271:9-14. doi: 10.1016/j.atherosclerosis.2018.02.012. Epub 2018 Feb 8.

PMID:
29453088
13.

Aggregatibacter actinomycetemcomitans serotypes associate with periodontal and coronary artery disease status.

Pietiäinen M, Kopra KAE, Vuorenkoski J, Salminen A, Paju S, Mäntylä P, Buhlin K, Liljestrand JM, Nieminen MS, Sinisalo J, Hyvärinen K, Pussinen PJ.

J Clin Periodontol. 2018 Apr;45(4):413-421. doi: 10.1111/jcpe.12873. Epub 2018 Mar 15.

PMID:
29385645
14.

Serum MMP-9 Diagnostics, Prognostics, and Activation in Acute Coronary Syndrome and Its Recurrence.

Lahdentausta L, Leskelä J, Winkelmann A, Tervahartiala T, Sorsa T, Pesonen E, Pussinen PJ.

J Cardiovasc Transl Res. 2018 Jun;11(3):210-220. doi: 10.1007/s12265-018-9789-x. Epub 2018 Jan 18.

15.

Immunologic burden links periodontitis to acute coronary syndrome.

Liljestrand JM, Paju S, Pietiäinen M, Buhlin K, Persson GR, Nieminen MS, Sinisalo J, Mäntylä P, Pussinen PJ.

Atherosclerosis. 2018 Jan;268:177-184. doi: 10.1016/j.atherosclerosis.2017.12.007. Epub 2017 Dec 6.

PMID:
29232563
16.

Genetic Variants Contributing to Circulating Matrix Metalloproteinase 8 Levels and Their Association With Cardiovascular Diseases: A Genome-Wide Analysis.

Salminen A, Vlachopoulou E, Havulinna AS, Tervahartiala T, Sattler W, Lokki ML, Nieminen MS, Perola M, Salomaa V, Sinisalo J, Meri S, Sorsa T, Pussinen PJ.

Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001731. doi: 10.1161/CIRCGENETICS.117.001731.

PMID:
29212897
17.

Oxidative Stress in the Local and Systemic Events of Apical Periodontitis.

Hernández-Ríos P, Pussinen PJ, Vernal R, Hernández M.

Front Physiol. 2017 Nov 1;8:869. doi: 10.3389/fphys.2017.00869. eCollection 2017. Review.

18.

HLA, infections and inflammation in early stages of atherosclerosis in children with type 1 diabetes.

Odermarsky M, Pesonen E, Sorsa T, Lernmark Å, Pussinen PJ, Liuba P.

Acta Diabetol. 2018 Jan;55(1):41-47. doi: 10.1007/s00592-017-1063-1. Epub 2017 Oct 24.

19.

Porphyromonas gingivalis may interfere with conception in women.

Paju S, Oittinen J, Haapala H, Asikainen S, Paavonen J, Pussinen PJ.

J Oral Microbiol. 2017 Jun 12;9(1):1330644. doi: 10.1080/20002297.2017.1330644. eCollection 2017.

20.

Oral health and systemic inflammatory, cardiac and nitroxid biomarkers in hemodialysis patients.

Cotič J, Ferran M, Karišik J, Jerin A, Pussinen PJ, Nemec A, Pavlica Z, Buturović-Ponikvar J, Petelin M.

Med Oral Patol Oral Cir Bucal. 2017 Jul 1;22(4):e432-e439.

21.

Lipopolysaccharide, a possible molecular mediator between periodontitis and coronary artery disease.

Liljestrand JM, Paju S, Buhlin K, Persson GR, Sarna S, Nieminen MS, Sinisalo J, Mäntylä P, Pussinen PJ.

J Clin Periodontol. 2017 Aug;44(8):784-792. doi: 10.1111/jcpe.12751. Epub 2017 Jul 7.

PMID:
28556187
22.

Cross-reactive saliva IgA antibodies to oxidized LDL and periodontal pathogens in humans.

Akhi R, Wang C, Kyrklund M, Kummu O, Turunen SP, Hyvärinen K, Kullaa A, Salo T, Pussinen PJ, Hörkkö S.

J Clin Periodontol. 2017 Jul;44(7):682-691. doi: 10.1111/jcpe.12748. Epub 2017 Jun 29.

PMID:
28548243
23.

Matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 predict incident cardiovascular disease events and all-cause mortality in a population-based cohort.

Kormi I, Nieminen MT, Havulinna AS, Zeller T, Blankenberg S, Tervahartiala T, Sorsa T, Salomaa V, Pussinen PJ.

Eur J Prev Cardiol. 2017 Jul;24(11):1136-1144. doi: 10.1177/2047487317706585. Epub 2017 Apr 21.

PMID:
28429955
24.

Intestinal alkaline phosphatase at the crossroad of intestinal health and disease - a putative role in type 1 diabetes.

Lassenius MI, Fogarty CL, Blaut M, Haimila K, Riittinen L, Paju A, Kirveskari J, Järvelä J, Ahola AJ, Gordin D, Härma MA, Kumar A, Hamarneh SR, Hodin RA, Sorsa T, Tervahartiala T, Hörkkö S, Pussinen PJ, Forsblom C, Jauhiainen M, Taskinen MR, Groop PH, Lehto M; FinnDiane Study Group.

J Intern Med. 2017 Jun;281(6):586-600. doi: 10.1111/joim.12607. Epub 2017 Apr 10.

25.

Low MMP-8/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome.

Parkkonen O, Nieminen MT, Vesterinen P, Tervahartiala T, Perola M, Salomaa V, Jousilahti P, Sorsa T, Pussinen PJ, Sinisalo J.

PLoS One. 2017 Mar 9;12(3):e0173371. doi: 10.1371/journal.pone.0173371. eCollection 2017.

26.

Response to Letter to the Editor, "Association of Endodontic Lesions with Coronary Artery Disease".

Liljestrand JM, Sinisalo J, Pussinen PJ.

J Dent Res. 2017 Feb;96(2):234. doi: 10.1177/0022034516681954. Epub 2016 Dec 5. No abstract available.

PMID:
27927889
27.

Association between infectious burden, socioeconomic status, and ischemic stroke.

Palm F, Pussinen PJ, Aigner A, Becher H, Buggle F, Bauer MF, Grond-Ginsbach C, Safer A, Urbanek C, Grau AJ.

Atherosclerosis. 2016 Nov;254:117-123. doi: 10.1016/j.atherosclerosis.2016.10.008. Epub 2016 Oct 5.

PMID:
27728851
28.

Mannose-binding lectin gene polymorphism in relation to periodontal infection.

Liukkonen A, He Q, Gürsoy UK, Pussinen PJ, Gröndahl-Yli-Hannuksela K, Liukkonen J, Sorsa T, Suominen AL, Huumonen S, Könönen E.

J Periodontal Res. 2017 Jun;52(3):540-545. doi: 10.1111/jre.12420. Epub 2016 Sep 14.

PMID:
27624657
29.

Salivary Concentrations of Interleukin (IL)-1β, IL-17A, and IL-23 Vary in Relation to Periodontal Status.

Liukkonen J, Gürsoy UK, Pussinen PJ, Suominen AL, Könönen E.

J Periodontol. 2016 Dec;87(12):1484-1491. Epub 2016 Aug 19.

PMID:
27541079
30.

Systemic Aggregatibacter actinomycetemcomitans Leukotoxin-Neutralizing Antibodies in Periodontitis.

Johansson A, Buhlin K, Sorsa T, Pussinen PJ.

J Periodontol. 2017 Jan;88(1):122-129. Epub 2016 Aug 13.

PMID:
27523521
31.

Association of Endodontic Lesions with Coronary Artery Disease.

Liljestrand JM, Mäntylä P, Paju S, Buhlin K, Kopra KA, Persson GR, Hernandez M, Nieminen MS, Sinisalo J, Tjäderhane L, Pussinen PJ.

J Dent Res. 2016 Nov;95(12):1358-1365. doi: 10.1177/0022034516660509. Epub 2016 Jul 28.

PMID:
27466397
32.

Practical implications of novel serum ELISA-assay for matrix metalloproteinase-8 in acute cardiac diagnostics.

Nieminen MT, Vesterinen P, Tervahartiala T, Kormi I, Sinisalo J, Pussinen PJ, Sorsa T.

Acute Card Care. 2015;17(3):46-7. doi: 10.3109/17482941.2015.1115077. Epub 2016 Mar 16.

PMID:
26982630
33.

Detection of hydrogen cyanide from oral anaerobes by cavity ring down spectroscopy.

Chen W, Roslund K, Fogarty CL, Pussinen PJ, Halonen L, Groop PH, Metsälä M, Lehto M.

Sci Rep. 2016 Mar 4;6:22577. doi: 10.1038/srep22577.

34.

Oral health: A modifiable risk factor for cardiovascular diseases or a confounded association?

Pussinen PJ, Könönen E.

Eur J Prev Cardiol. 2016 May;23(8):834-8. doi: 10.1177/2047487316636506. Epub 2016 Feb 25. No abstract available.

PMID:
26915578
35.

Analysis of matrix metalloproteinases, especially MMP-8, in gingival creviclular fluid, mouthrinse and saliva for monitoring periodontal diseases.

Sorsa T, Gursoy UK, Nwhator S, Hernandez M, Tervahartiala T, Leppilahti J, Gursoy M, Könönen E, Emingil G, Pussinen PJ, Mäntylä P.

Periodontol 2000. 2016 Feb;70(1):142-63. doi: 10.1111/prd.12101. Review.

PMID:
26662488
36.

Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease.

Alfakry H, Malle E, Koyani CN, Pussinen PJ, Sorsa T.

Innate Immun. 2016 Jan;22(1):85-99. doi: 10.1177/1753425915617521. Epub 2015 Nov 24. Review.

PMID:
26608308
37.

Quantitative PCR analysis of salivary pathogen burden in periodontitis.

Salminen A, Kopra KA, Hyvärinen K, Paju S, Mäntylä P, Buhlin K, Nieminen MS, Sinisalo J, Pussinen PJ.

Front Cell Infect Microbiol. 2015 Oct 1;5:69. doi: 10.3389/fcimb.2015.00069. eCollection 2015.

38.

Association of periodontitis with persistent, pro-atherogenic antibody responses.

Buhlin K, Holmer J, Gustafsson A, Hörkkö S, Pockley AG, Johansson A, Paju S, Klinge B, Pussinen PJ.

J Clin Periodontol. 2015 Nov;42(11):1006-14. doi: 10.1111/jcpe.12456. Epub 2015 Nov 3.

PMID:
26362847
39.

Missing Teeth Predict Incident Cardiovascular Events, Diabetes, and Death.

Liljestrand JM, Havulinna AS, Paju S, Männistö S, Salomaa V, Pussinen PJ.

J Dent Res. 2015 Aug;94(8):1055-62. doi: 10.1177/0022034515586352. Epub 2015 May 19.

PMID:
25991651
40.

Matrix metalloproteinase 8 degrades apolipoprotein A-I and reduces its cholesterol efflux capacity.

Salminen A, Åström P, Metso J, Soliymani R, Salo T, Jauhiainen M, Pussinen PJ, Sorsa T.

FASEB J. 2015 Apr;29(4):1435-45. doi: 10.1096/fj.14-262956. Epub 2014 Dec 30.

PMID:
25550459
41.

Endotoxemia, nutrition, and cardiometabolic disorders.

Kallio KA, Hätönen KA, Lehto M, Salomaa V, Männistö S, Pussinen PJ.

Acta Diabetol. 2015 Apr;52(2):395-404. doi: 10.1007/s00592-014-0662-3. Epub 2014 Oct 19.

PMID:
25326898
42.

Antibodies to periodontal pathogens are associated with coronary plaque remodeling but not with vulnerability or burden.

de Boer SP, Cheng JM, Rangé H, Garcia-Garcia HM, Heo JH, Akkerhuis KM, Meilhac O, Cosler G, Pussinen PJ, van Geuns RJ, Serruys PW, Boersma E, Kardys I.

Atherosclerosis. 2014 Nov;237(1):84-91. doi: 10.1016/j.atherosclerosis.2014.08.050. Epub 2014 Sep 6.

PMID:
25233105
43.

Immunization with malondialdehyde-modified low-density lipoprotein (LDL) reduces atherosclerosis in LDL receptor-deficient mice challenged with Porphyromonas gingivalis.

Turunen SP, Kummu O, Wang C, Harila K, Mattila R, Sahlman M, Pussinen PJ, Hörkkö S.

Innate Immun. 2015 May;21(4):370-85. doi: 10.1177/1753425914542444. Epub 2014 Aug 17.

PMID:
25134521
44.

Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals.

Lassenius MI, Mäkinen VP, Fogarty CL, Peräneva L, Jauhiainen M, Pussinen PJ, Taskinen MR, Kirveskari J, Vaarala O, Nieminen JK, Hörkkö S, Kangas AJ, Soininen P, Ala-Korpela M, Gordin D, Ahola AJ, Forsblom C, Groop PH, Lehto M.

Nutr Metab (Lond). 2014 Jun 13;11:28. doi: 10.1186/1743-7075-11-28. eCollection 2014.

45.

Systemic exposure to a common periodontal pathogen and missing teeth are associated with metabolic syndrome.

Hyvärinen K, Salminen A, Salomaa V, Pussinen PJ.

Acta Diabetol. 2015 Feb;52(1):179-82. doi: 10.1007/s00592-014-0586-y. Epub 2014 May 5.

PMID:
24791962
46.

Genetic variation on the BAT1-NFKBIL1-LTA region of major histocompatibility complex class III associates with periodontitis.

Kallio KA, Marchesani M, Vlachopoulou E, Mäntylä P, Paju S, Buhlin K, Suominen AL, Contreras J, Knuuttila M, Hernandez M, Huumonen S, Nieminen MS, Perola M, Sinisalo J, Lokki ML, Pussinen PJ.

Infect Immun. 2014 May;82(5):1939-48. doi: 10.1128/IAI.01681-13. Epub 2014 Feb 24.

47.

Salivary biomarkers of bacterial burden, inflammatory response, and tissue destruction in periodontitis.

Salminen A, Gursoy UK, Paju S, Hyvärinen K, Mäntylä P, Buhlin K, Könönen E, Nieminen MS, Sorsa T, Sinisalo J, Pussinen PJ.

J Clin Periodontol. 2014 May;41(5):442-50. doi: 10.1111/jcpe.12234. Epub 2014 Feb 17.

PMID:
24460823
48.

The effect of prolonged systemic doxycycline therapy on serum tissue degrading proteinases in coronary bypass patients: a randomized, double-masked, placebo-controlled clinical trial.

Kormi I, Alfakry H, Tervahartiala T, Pussinen PJ, Sinisalo J, Sorsa T.

Inflamm Res. 2014 May;63(5):329-34. doi: 10.1007/s00011-013-0704-2. Epub 2013 Dec 31.

PMID:
24378958
49.

Letters to the editor: authors' response.

Gürsoy UK, Huumonen S, Vesti E, Pussinen PJ, Suominen AL, Könönen E.

J Periodontol. 2014 Jan;85(1):12-3. doi: 10.1902/jop.2013.130162. No abstract available.

PMID:
24364837
50.

Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene polymorphisms in generalized aggressive periodontitis: gingival crevicular fluid MMP-8 and TIMP-1 levels and outcome of periodontal therapy.

Emingil G, Han B, Gürkan A, Berdeli A, Tervahartiala T, Salo T, Pussinen PJ, Köse T, Atilla G, Sorsa T.

J Periodontol. 2014 Aug;85(8):1070-80. doi: 10.1902/jop.2013.130365. Epub 2013 Nov 28.

PMID:
24283658

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