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Items: 1 to 50 of 160

1.

A convenient approach for the preparation of imidazo[1,2-a]-fused bicyclic frameworks via IBX/NIS promoted oxidative annulation.

Makra Z, Puskás LG, Kanizsai I.

Org Biomol Chem. 2019 Oct 28;17(40):9001-9007. doi: 10.1039/c9ob01708a. Epub 2019 Oct 2.

PMID:
31577318
2.

Signatures of cell death and proliferation in perturbation transcriptomics data-from confounding factor to effective prediction.

Szalai B, Subramanian V, Holland CH, Alföldi R, Puskás LG, Saez-Rodriguez J.

Nucleic Acids Res. 2019 Nov 4;47(19):10010-10026. doi: 10.1093/nar/gkz805.

3.

Single Cell Mass Cytometry of Non-Small Cell Lung Cancer Cells Reveals Complexity of In vivo And Three-Dimensional Models over the Petri-dish.

Alföldi R, Balog JÁ, Faragó N, Halmai M, Kotogány E, Neuperger P, Nagy LI, Fehér LZ, Szebeni GJ, Puskás LG.

Cells. 2019 Sep 16;8(9). pii: E1093. doi: 10.3390/cells8091093.

4.

Multilevel structure-activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism.

Fenteany G, Gaur P, Hegedűs L, Dudás K, Kiss E, Wéber E, Hackler L, Martinek T, Puskás LG, Haracska L.

Sci Rep. 2019 Sep 5;9(1):12801. doi: 10.1038/s41598-019-48888-6.

5.

Selective Heart Irradiation Induces Cardiac Overexpression of the Pro-hypertrophic miR-212.

Sárközy M, Gáspár R, Zvara Á, Kiscsatári L, Varga Z, Kővári B, Kovács MG, Szűcs G, Fábián G, Diószegi P, Cserni G, Puskás LG, Thum T, Kahán Z, Csont T, Bátkai S.

Front Oncol. 2019 Jul 16;9:598. doi: 10.3389/fonc.2019.00598. eCollection 2019.

6.

The Anti-Inflammatory Role of Mannich Curcuminoids; Special Focus on Colitis.

Szebeni GJ, Nagy LI, Berkó A, Hoffmann A, Fehér LZ, Bagyánszki M, Kari B, Balog JA, Hackler L Jr, Kanizsai I, Pósa A, Varga C, Puskás LG.

Molecules. 2019 Apr 19;24(8). pii: E1546. doi: 10.3390/molecules24081546.

7.

1,3-Dipolar Cycloaddition of Isatin-Derived Azomethine Ylides with 2 H-Azirines: Stereoselective Synthesis of 1,3-Diazaspiro[bicyclo[3.1.0]hexane]oxindoles.

Angyal A, Demjén A, Harmat V, Wölfling J, Puskás LG, Kanizsai I.

J Org Chem. 2019 Apr 5;84(7):4273-4281. doi: 10.1021/acs.joc.9b00242. Epub 2019 Mar 19.

PMID:
30860375
8.

Sensory Neuropathy Affects Cardiac miRNA Expression Network Targeting IGF-1, SLC2a-12, EIF-4e, and ULK-2 mRNAs.

Bencsik P, Kiss K, Ágg B, Baán JA, Ágoston G, Varga A, Gömöri K, Mendler L, Faragó N, Zvara Á, Sántha P, Puskás LG, Jancsó G, Ferdinandy P.

Int J Mol Sci. 2019 Feb 25;20(4). pii: E991. doi: 10.3390/ijms20040991.

9.

Chronic kidney disease induces left ventricular overexpression of the pro-hypertrophic microRNA-212.

Sárközy M, Gáspár R, Zvara Á, Siska A, Kővári B, Szűcs G, Márványkövi F, Kovács MG, Diószegi P, Bodai L, Zsindely N, Pipicz M, Gömöri K, Kiss K, Bencsik P, Cserni G, Puskás LG, Földesi I, Thum T, Bátkai S, Csont T.

Sci Rep. 2019 Feb 4;9(1):1302. doi: 10.1038/s41598-018-37690-5.

10.

Expression of GLP-1 receptors in insulin-containing interneurons of rat cerebral cortex.

Csajbók ÉA, Kocsis ÁK, Faragó N, Furdan S, Kovács B, Lovas S, Molnár G, Likó I, Zvara Á, Puskás LG, Patócs A, Tamás G.

Diabetologia. 2019 Apr;62(4):717-725. doi: 10.1007/s00125-018-4803-z. Epub 2019 Jan 12.

PMID:
30637442
11.

Cerebrovascular Pathology in Hypertriglyceridemic APOB-100 Transgenic Mice.

Hoyk Z, Tóth ME, Lénárt N, Nagy D, Dukay B, Csefová A, Zvara Á, Seprényi G, Kincses A, Walter FR, Veszelka S, Vígh J, Barabási B, Harazin A, Kittel Á, Puskás LG, Penke B, Vígh L, Deli MA, Sántha M.

Front Cell Neurosci. 2018 Oct 25;12:380. doi: 10.3389/fncel.2018.00380. eCollection 2018.

12.

Imidazo[1,2-b]pyrazole-7-carboxamides Induce Apoptosis in Human Leukemia Cells at Nanomolar Concentrations.

Szebeni GJ, Balog JA, Demjén A, Alföldi R, Végi VL, Fehér LZ, Mán I, Kotogány E, Gubán B, Batár P, Hackler L Jr, Kanizsai I, Puskás LG.

Molecules. 2018 Nov 1;23(11). pii: E2845. doi: 10.3390/molecules23112845.

13.

Enhancing the Translational Capacity of E. coli by Resolving the Codon Bias.

Lipinszki Z, Vernyik V, Farago N, Sari T, Puskas LG, Blattner FR, Posfai G, Gyorfy Z.

ACS Synth Biol. 2018 Nov 16;7(11):2656-2664. doi: 10.1021/acssynbio.8b00332. Epub 2018 Nov 2.

PMID:
30351909
14.

Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type.

Boldog E, Bakken TE, Hodge RD, Novotny M, Aevermann BD, Baka J, Bordé S, Close JL, Diez-Fuertes F, Ding SL, Faragó N, Kocsis ÁK, Kovács B, Maltzer Z, McCorrison JM, Miller JA, Molnár G, Oláh G, Ozsvár A, Rózsa M, Shehata SI, Smith KA, Sunkin SM, Tran DN, Venepally P, Wall A, Puskás LG, Barzó P, Steemers FJ, Schork NJ, Scheuermann RH, Lasken RS, Lein ES, Tamás G.

Nat Neurosci. 2018 Sep;21(9):1185-1195. doi: 10.1038/s41593-018-0205-2. Epub 2018 Aug 27.

15.

Author Correction: MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium.

Ágg B, Baranyai T, Makkos A, Vető B, Faragó N, Zvara Á, Giricz Z, Veres DV, Csermely P, Arányi T, Puskás LG, Varga ZV, Ferdinandy P.

Sci Rep. 2018 Aug 9;8(1):12159. doi: 10.1038/s41598-018-30163-9.

16.

Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products.

Kanizsai I, Madácsi R, Hackler L Jr, Gyuris M, Szebeni GJ, Huzián O, Puskás LG.

Molecules. 2018 Aug 2;23(8). pii: E1934. doi: 10.3390/molecules23081934.

17.

The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl- Channel.

Venglovecz V, Pallagi P, Kemény LV, Balázs A, Balla Z, Becskeházi E, Gál E, Tóth E, Zvara Á, Puskás LG, Borka K, Sendler M, Lerch MM, Mayerle J, Kühn JP, Rakonczay Z Jr, Hegyi P.

Front Physiol. 2018 Jul 12;9:854. doi: 10.3389/fphys.2018.00854. eCollection 2018.

18.

MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium.

Ágg B, Baranyai T, Makkos A, Vető B, Faragó N, Zvara Á, Giricz Z, Veres DV, Csermely P, Arányi T, Puskás LG, Varga ZV, Ferdinandy P.

Sci Rep. 2018 Jul 4;8(1):10134. doi: 10.1038/s41598-018-27740-3. Erratum in: Sci Rep. 2018 Aug 9;8(1):12159.

19.

Synthesis, cytotoxic characterization, and SAR study of imidazo[1,2-b]pyrazole-7-carboxamides.

Demjén A, Alföldi R, Angyal A, Gyuris M, Hackler L Jr, Szebeni GJ, Wölfling J, Puskás LG, Kanizsai I.

Arch Pharm (Weinheim). 2018 Jul;351(7):e1800062. doi: 10.1002/ardp.201800062. Epub 2018 Jun 10.

PMID:
29888449
20.

Synthesis of N-peptide-6-amino-D-luciferin Conjugates.

Kovács AK, Hegyes P, Szebeni GJ, Nagy LI, Puskás LG, Tóth GK.

Front Chem. 2018 Apr 19;6:120. doi: 10.3389/fchem.2018.00120. eCollection 2018.

21.

One-pot synthesis of diverse N,N'-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines via N-phthaloyl-guanidines.

Demjén A, Angyal A, Wölfling J, Puskás LG, Kanizsai I.

Org Biomol Chem. 2018 Mar 28;16(12):2143-2149. doi: 10.1039/c7ob03109b. Epub 2018 Mar 8.

PMID:
29517090
22.

Lewis Acid-Catalyzed Diastereoselective Synthesis of Multisubstituted N-Acylaziridine-2-carboxamides from 2 H-Azirines via Joullié-Ugi Three-Component Reaction.

Angyal A, Demjén A, Wéber E, Kovács AK, Wölfling J, Puskás LG, Kanizsai I.

J Org Chem. 2018 Apr 6;83(7):3570-3581. doi: 10.1021/acs.joc.7b03189. Epub 2018 Mar 9.

PMID:
29498845
23.

Intelligent image-based in situ single-cell isolation.

Brasko C, Smith K, Molnar C, Farago N, Hegedus L, Balind A, Balassa T, Szkalisity A, Sukosd F, Kocsis K, Balint B, Paavolainen L, Enyedi MZ, Nagy I, Puskas LG, Haracska L, Tamas G, Horvath P.

Nat Commun. 2018 Jan 15;9(1):226. doi: 10.1038/s41467-017-02628-4.

24.

Decoding DNA labels by melting curve analysis using real-time PCR.

Balog JA, Fehér LZ, Puskás LG.

Biotechniques. 2017 Dec 1;63(6):261-266. doi: 10.2144/000114618.

25.

Achiral Mannich-Base Curcumin Analogs Induce Unfolded Protein Response and Mitochondrial Membrane Depolarization in PANC-1 Cells.

Szebeni GJ, Balázs Á, Madarász I, Pócz G, Ayaydin F, Kanizsai I, Fajka-Boja R, Alföldi R, Hackler L Jr, Puskás LG.

Int J Mol Sci. 2017 Oct 7;18(10). pii: E2105. doi: 10.3390/ijms18102105.

26.

Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas.

Csonka C, Baranyai T, Tiszlavicz L, Fébel H, Szűcs G, Varga ZV, Sárközy M, Puskás LG, Antal O, Siska A, Földesi I, Ferdinandy P, Czakó L, Csont T.

Lipids Health Dis. 2017 Jul 27;16(1):144. doi: 10.1186/s12944-017-0537-z.

27.

Mannich Curcuminoids as Potent Anticancer Agents.

Gyuris M, Hackler L Jr, Nagy LI, Alföldi R, Rédei E, Marton A, Vellai T, Faragó N, Ózsvári B, Hetényi A, Tóth GK, Sipos P, Kanizsai I, Puskás LG.

Arch Pharm (Weinheim). 2017 Jul;350(7). doi: 10.1002/ardp.201700005. Epub 2017 May 26.

PMID:
28547897
28.

A novel pleiotropic effect of aspirin: Beneficial regulation of pro- and anti-inflammatory mechanisms in microglial cells.

Kata D, Földesi I, Feher LZ, Hackler L Jr, Puskas LG, Gulya K.

Brain Res Bull. 2017 Jun;132:61-74. doi: 10.1016/j.brainresbull.2017.05.009. Epub 2017 May 18.

PMID:
28528204
29.

The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.

Kovács T, Billes V, Komlós M, Hotzi B, Manzéger A, Tarnóci A, Papp D, Szikszai F, Szinyákovics J, Rácz Á, Noszál B, Veszelka S, Walter FR, Deli MA, Hackler L Jr, Alfoldi R, Huzian O, Puskas LG, Liliom H, Tárnok K, Schlett K, Borsy A, Welker E, Kovács AL, Pádár Z, Erdős A, Legradi A, Bjelik A, Gulya K, Gulyás B, Vellai T.

Sci Rep. 2017 Feb 16;7:42014. doi: 10.1038/srep42014.

30.

Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters.

Szebeni GJ, Vizler C, Kitajka K, Puskas LG.

Mediators Inflamm. 2017;2017:9294018. doi: 10.1155/2017/9294018. Epub 2017 Jan 18. Review.

31.

Real architecture For 3D Tissue (RAFT™) culture system improves viability and maintains insulin and glucagon production of mouse pancreatic islet cells.

Szebeni GJ, Tancos Z, Feher LZ, Alfoldi R, Kobolak J, Dinnyes A, Puskas LG.

Cytotechnology. 2017 Apr;69(2):359-369. doi: 10.1007/s10616-017-0067-6. Epub 2017 Feb 8.

32.

Pro-Tumoral Inflammatory Myeloid Cells as Emerging Therapeutic Targets.

Szebeni GJ, Vizler C, Nagy LI, Kitajka K, Puskas LG.

Int J Mol Sci. 2016 Nov 23;17(11). pii: E1958. Review.

33.

Human neuronal changes in brain edema and increased intracranial pressure.

Faragó N, Kocsis ÁK, Braskó C, Lovas S, Rózsa M, Baka J, Kovács B, Mikite K, Szemenyei V, Molnár G, Ozsvár A, Oláh G, Piszár I, Zvara Á, Patócs A, Barzó P, Puskás LG, Tamás G.

Acta Neuropathol Commun. 2016 Aug 4;4(1):78. doi: 10.1186/s40478-016-0356-x.

34.

Structural and molecular features of intestinal strictures in rats with Crohn's-like disease.

Talapka P, Berkó A, Nagy LI, Chandrakumar L, Bagyánszki M, Puskás LG, Fekete É, Bódi N.

World J Gastroenterol. 2016 Jun 14;22(22):5154-64. doi: 10.3748/wjg.v22.i22.5154.

35.

The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo.

Hackler L Jr, Ózsvári B, Gyuris M, Sipos P, Fábián G, Molnár E, Marton A, Faragó N, Mihály J, Nagy LI, Szénási T, Diron A, Párducz Á, Kanizsai I, Puskás LG.

PLoS One. 2016 Mar 4;11(3):e0149832. doi: 10.1371/journal.pone.0149832. eCollection 2016.

36.

Novel Anti-CRR9/CLPTM1L Antibodies with Antitumorigenic Activity Inhibit Cell Surface Accumulation, PI3K Interaction, and Survival Signaling.

Puskás LG, Mán I, Szebeni G, Tiszlavicz L, Tsai S, James MA.

Mol Cancer Ther. 2016 May;15(5):985-97. doi: 10.1158/1535-7163.MCT-15-0717. Epub 2016 Mar 3.

37.

Investigation of the Antiproliferative Properties of Natural Sesquiterpenes from Artemisia asiatica and Onopordum acanthium on HL-60 Cells in Vitro.

Molnár J, Szebeni GJ, Csupor-Löffler B, Hajdú Z, Szekeres T, Saiko P, Ocsovszki I, Puskás LG, Hohmann J, Zupkó I.

Int J Mol Sci. 2016 Feb 17;17(2):83. doi: 10.3390/ijms17020083.

38.

[The potential of three-dimensional tumor models and cell culturing in cancer research and diagnostics].

Alföldi R, Szebeni JG, Puskás LG.

Magy Onkol. 2015 Dec;59(4):303-9. Epub 2015 Jul 15. Hungarian.

39.

Rosuvastatin enhances anti-inflammatory and inhibits pro-inflammatory functions in cultured microglial cells.

Kata D, Földesi I, Feher LZ, Hackler L Jr, Puskas LG, Gulya K.

Neuroscience. 2016 Feb 9;314:47-63. doi: 10.1016/j.neuroscience.2015.11.053. Epub 2015 Nov 26.

40.

The importance of microenvironment: the role of CCL8 in metastasis formation of melanoma.

Barbai T, Fejős Z, Puskas LG, Tímár J, Rásó E.

Oncotarget. 2015 Oct 6;6(30):29111-28. doi: 10.18632/oncotarget.5059.

41.

AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects.

Papp D, Kovács T, Billes V, Varga M, Tarnóci A, Hackler L Jr, Puskás LG, Liliom H, Tárnok K, Schlett K, Borsy A, Pádár Z, Kovács AL, Hegedűs K, Juhász G, Komlós M, Erdős A, Gulyás B, Vellai T.

Autophagy. 2016;12(2):273-86. doi: 10.1080/15548627.2015.1082023.

42.

Cultured cells of the blood-brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment.

Lénárt N, Walter FR, Bocsik A, Sántha P, Tóth ME, Harazin A, Tóth AE, Vizler C, Török Z, Pilbat AM, Vígh L, Puskás LG, Sántha M, Deli MA.

Fluids Barriers CNS. 2015 Jul 17;12:17. doi: 10.1186/s12987-015-0013-y.

43.

The effect of a preparation of minerals, vitamins and trace elements on the cardiac gene expression pattern in male diabetic rats.

Sárközy M, Szűcs G, Pipicz M, Zvara Á, Éder K, Fekete V, Szűcs C, Bárkányi J, Csonka C, Puskás LG, Kónya C, Ferdinandy P, Csont T.

Cardiovasc Diabetol. 2015 Jun 28;14:85. doi: 10.1186/s12933-015-0248-6.

44.

Novel real-time cell analysis platform for the dynamic monitoring of ionizing radiation effects on human tumor cell lines and primary fibroblasts.

Mán I, Szebeni GJ, Plangár I, Szabó ER, Tőkés T, Szabó Z, Nagy Z, Fekete G, Fajka-Boja R, Puskás LG, Hideghéty K, Hackler L Jr.

Mol Med Rep. 2015 Sep;12(3):4610-1619. doi: 10.3892/mmr.2015.4004. Epub 2015 Jun 26.

PMID:
26126392
45.

Lipidomic analysis reveals a radiosensitizing role of gamma-linolenic acid in glioma cells.

Antal O, Péter M, Hackler L Jr, Mán I, Szebeni G, Ayaydin F, Hideghéty K, Vigh L, Kitajka K, Balogh G, Puskás LG.

Biochim Biophys Acta. 2015 Sep;1851(9):1271-82. doi: 10.1016/j.bbalip.2015.06.003. Epub 2015 Jun 16.

PMID:
26092623
46.

Curcumin and its analogue induce apoptosis in leukemia cells and have additive effects with bortezomib in cellular and xenograft models.

Nagy LI, Fehér LZ, Szebeni GJ, Gyuris M, Sipos P, Alföldi R, Ózsvári B, Hackler L Jr, Balázs A, Batár P, Kanizsai I, Puskás LG.

Biomed Res Int. 2015;2015:968981. doi: 10.1155/2015/968981. Epub 2015 May 17.

47.

Functional Genomics of Cardioprotection by Ischemic Conditioning and the Influence of Comorbid Conditions: Implications in Target Identification.

Varga ZV, Giricz Z, Bencsik P, Madonna R, Gyongyosi M, Schulz R, Mayr M, Thum T, Puskas LG, Ferdinandy P.

Curr Drug Targets. 2015;16(8):904-11. Review.

PMID:
25915487
48.

Tissue-specific Gene Expression in Rat Hearts and Aortas in a Model of Vascular Nitrate Tolerance.

Csont T, Murlasits Z, Ménesi D, Kelemen JZ, Bencsik P, Pipicz M, Fekete V, Zvara Á, Puskás LG, Ferdinandy P.

J Cardiovasc Pharmacol. 2015 May;65(5):485-93. doi: 10.1097/FJC.0000000000000218.

PMID:
25626975
49.

Characterization of a new class of blue-fluorescent lipid droplet markers for live-cell imaging in plants.

Kuntam S, Puskás LG, Ayaydin F.

Plant Cell Rep. 2015 Apr;34(4):655-65. doi: 10.1007/s00299-015-1738-4. Epub 2015 Jan 21.

PMID:
25604989
50.

Neutrophils are required for both the sensitization and elicitation phase of contact hypersensitivity.

Weber FC, Németh T, Csepregi JZ, Dudeck A, Roers A, Ozsvári B, Oswald E, Puskás LG, Jakob T, Mócsai A, Martin SF.

J Exp Med. 2015 Jan 12;212(1):15-22. doi: 10.1084/jem.20130062. Epub 2014 Dec 15.

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