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A novel glucocorticoid-free maintenance regimen for anti-neutrophil cytoplasm antibody-associated vasculitis.

Pepper RJ, McAdoo SP, Moran SM, Kelly D, Scott J, Hamour S, Burns A, Griffith M, Galliford J, Levy JB, Cairns TD, Gopaluni S, Jones RB, Jayne D, Little MA, Pusey CD, Salama AD.

Rheumatology (Oxford). 2019 Feb 1;58(2):373. doi: 10.1093/rheumatology/kez001. No abstract available.


Antiglomerular Basement Membrane Disease.

McAdoo SP, Pusey CD.

Semin Respir Crit Care Med. 2018 Aug;39(4):494-503. doi: 10.1055/s-0038-1669413. Epub 2018 Nov 7. Review.


High Incidence of Arterial and Venous Thrombosis in Antineutrophil Cytoplasmic Antibody-associated Vasculitis.

Kang A, Antonelou M, Wong NL, Tanna A, Arulkumaran N, Tam FWK, Pusey CD.

J Rheumatol. 2019 Mar;46(3):285-293. doi: 10.3899/jrheum.170896. Epub 2018 Nov 1.


Peroxidasin-a Novel Autoantigen in Anti-GBM Disease?

McAdoo SP, Pusey CD.

J Am Soc Nephrol. 2018 Nov;29(11):2605-2607. doi: 10.1681/ASN.2018090946. Epub 2018 Oct 12. No abstract available.


A novel glucocorticoid-free maintenance regimen for anti-neutrophil cytoplasm antibody-associated vasculitis.

Pepper RJ, McAdoo SP, Moran SM, Kelly D, Scott J, Hamour S, Burns A, Griffith M, Galliford J, Levy JB, Cairns TD, Gopaluni S, Jones RB, Jayne D, Little MA, Pusey CD, Salama AD.

Rheumatology (Oxford). 2019 Feb 1;58(2):260-268. doi: 10.1093/rheumatology/key288.


Alkylating histone deacetylase inhibitors may have therapeutic value in experimental myeloperoxidase-ANCA vasculitis.

Dooley D, van Timmeren MM, O'Reilly VP, Brady G, O'Brien EC, Fazekas B, Hickey FB, Leacy E, Pusey CD, Tam FWK, Mehrling T, Heeringa P, Little MA.

Kidney Int. 2018 Nov;94(5):926-936. doi: 10.1016/j.kint.2018.05.028. Epub 2018 Aug 26.


Recent advances in understanding of the pathogenesis of ANCA-associated vasculitis.

Prendecki M, Pusey CD.

F1000Res. 2018 Jul 19;7. pii: F1000 Faculty Rev-1113. doi: 10.12688/f1000research.14626.1. eCollection 2018. Review.


Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition.

Medjeral-Thomas NR, Troldborg A, Constantinou N, Lomax-Browne HJ, Hansen AG, Willicombe M, Pusey CD, Cook HT, Thiel S, Pickering MC.

Kidney Int Rep. 2017 Nov 29;3(2):426-438. doi: 10.1016/j.ekir.2017.11.015. eCollection 2018 Mar.


Long-term follow-up of a combined rituximab and cyclophosphamide regimen in renal anti-neutrophil cytoplasm antibody-associated vasculitis.

McAdoo SP, Medjeral-Thomas N, Gopaluni S, Tanna A, Mansfield N, Galliford J, Griffith M, Levy J, Cairns TD, Jayne D, Salama AD, Pusey CD.

Nephrol Dial Transplant. 2018 May 1;33(5):899. doi: 10.1093/ndt/gfy075. No abstract available.


Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA.

Kraaij T, Kamerling SWA, van Dam LS, Bakker JA, Bajema IM, Page T, Brunini F, Pusey CD, Toes REM, Scherer HU, Rabelink TJ, van Kooten C, Teng YKO.

Kidney Int. 2018 Jul;94(1):139-149. doi: 10.1016/j.kint.2018.01.013. Epub 2018 Mar 30.


Increased Prevalence of Thyroid Disease in Patients with Antineutrophil Cytoplasmic Antibodies-associated Vasculitis.

Prendecki M, Martin L, Tanna A, Antonelou M, Pusey CD.

J Rheumatol. 2018 May;45(5):686-689. doi: 10.3899/jrheum.170661. Epub 2018 Mar 15.


RIPK3-deficient mice were not protected from nephrotoxic nephritis.

Hill NR, Cook HT, Pusey CD, Tarzi RM.

BMC Nephrol. 2018 Mar 14;19(1):61. doi: 10.1186/s12882-018-0850-4.


Long-term follow-up of a combined rituximab and cyclophosphamide regimen in renal anti-neutrophil cytoplasm antibody-associated vasculitis.

McAdoo SP, Medjeral-Thomas N, Gopaluni S, Tanna A, Mansfield N, Galliford J, Griffith M, Levy J, Cairns TD, Jayne D, Salama AD, Pusey CD.

Nephrol Dial Transplant. 2019 Jan 1;34(1):63-73. doi: 10.1093/ndt/gfx378.


Defining Phenotypes in Diabetic Nephropathy: a novel approach using a cross-sectional analysis of a single centre cohort.

Montero RM, Herath A, Qureshi A, Esfandiari E, Pusey CD, Frankel AH, Tam FWK.

Sci Rep. 2018 Jan 8;8(1):53. doi: 10.1038/s41598-017-18595-1.


TESTING Corticosteroids in IgA Nephropathy: A Continuing Challenge.

Tam FWK, Pusey CD.

Clin J Am Soc Nephrol. 2018 Jan 6;13(1):158-160. doi: 10.2215/CJN.10560917. Epub 2017 Dec 13. No abstract available.


Predicting Outcome in Patients with Anti-GBM Glomerulonephritis.

van Daalen EE, Jennette JC, McAdoo SP, Pusey CD, Alba MA, Poulton CJ, Wolterbeek R, Nguyen TQ, Goldschmeding R, Alchi B, Griffiths M, de Zoysa JR, Vincent B, Bruijn JA, Bajema IM.

Clin J Am Soc Nephrol. 2018 Jan 6;13(1):63-72. doi: 10.2215/CJN.04290417. Epub 2017 Nov 21.


Positive antineutrophil cytoplasmic antibody serology in patients with lupus nephritis is associated with distinct histopathologic features on renal biopsy.

Turner-Stokes T, Wilson HR, Morreale M, Nunes A, Cairns T, Cook HT, Pusey CD, Tarzi RM, Lightstone L.

Kidney Int. 2017 Nov;92(5):1223-1231. doi: 10.1016/j.kint.2017.04.029. Epub 2017 Jul 24.


Circulating complement factor H-related proteins 1 and 5 correlate with disease activity in IgA nephropathy.

Medjeral-Thomas NR, Lomax-Browne HJ, Beckwith H, Willicombe M, McLean AG, Brookes P, Pusey CD, Falchi M, Cook HT, Pickering MC.

Kidney Int. 2017 Oct;92(4):942-952. doi: 10.1016/j.kint.2017.03.043. Epub 2017 Jun 30.


Anti-Glomerular Basement Membrane Disease.

McAdoo SP, Pusey CD.

Clin J Am Soc Nephrol. 2017 Jul 7;12(7):1162-1172. doi: 10.2215/CJN.01380217. Epub 2017 May 17. Review.


Patients double-seropositive for ANCA and anti-GBM antibodies have varied renal survival, frequency of relapse, and outcomes compared to single-seropositive patients.

McAdoo SP, Tanna A, Hrušková Z, Holm L, Weiner M, Arulkumaran N, Kang A, Satrapová V, Levy J, Ohlsson S, Tesar V, Segelmark M, Pusey CD.

Kidney Int. 2017 Sep;92(3):693-702. doi: 10.1016/j.kint.2017.03.014. Epub 2017 May 12.


Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function.

Chen TD, Rotival M, Chiu LY, Bagnati M, Ko JH, Srivastava PK, Petretto E, Pusey CD, Lai PC, Aitman TJ, Cook HT, Behmoaras J.

Genetics. 2017 Jun;206(2):1139-1151. doi: 10.1534/genetics.116.197376. Epub 2017 Apr 26.


Long-term outcome in biopsy-proven acute interstitial nephritis treated with steroids.

Prendecki M, Tanna A, Salama AD, Tam FW, Cairns T, Taube D, Cook HT, Ashby D, Duncan ND, Pusey CD.

Clin Kidney J. 2017 Apr;10(2):233-239. doi: 10.1093/ckj/sfw116. Epub 2016 Dec 24.


Is there a role for TNFα blockade in ANCA-associated vasculitis and glomerulonephritis?

McAdoo SP, Pusey CD.

Nephrol Dial Transplant. 2017 Jan 1;32(suppl_1):i80-i88. doi: 10.1093/ndt/gfw361. Review.


The Histopathological Classification of ANCA-associated Glomerulonephritis Comes of Age.

Tanna A, Pusey CD.

J Rheumatol. 2017 Mar;44(3):265-267. doi: 10.3899/jrheum.170006. No abstract available.


ANCA-Associated Glomerulonephritis: Risk Factors for Renal Relapse.

Göçeroğlu A, Berden AE, Fiocco M, Floßmann O, Westman KW, Ferrario F, Gaskin G, Pusey CD, Hagen EC, Noël LH, Rasmussen N, Waldherr R, Walsh M, Bruijn JA, Jayne DR, Bajema IM; European Vasculitis Society (EUVAS).

PLoS One. 2016 Dec 14;11(12):e0165402. doi: 10.1371/journal.pone.0165402. eCollection 2016.


Changes in urinary metabolomic profile during relapsing renal vasculitis.

Al-Ani B, Fitzpatrick M, Al-Nuaimi H, Coughlan AM, Hickey FB, Pusey CD, Savage C, Benton CM, O'Brien EC, O'Toole D, Mok KH, Young SP, Little MA.

Sci Rep. 2016 Dec 1;6:38074. doi: 10.1038/srep38074.


The role of monocytes in ANCA-associated vasculitides.

Brunini F, Page TH, Gallieni M, Pusey CD.

Autoimmun Rev. 2016 Nov;15(11):1046-1053. doi: 10.1016/j.autrev.2016.07.031. Epub 2016 Aug 1. Review.


Clustering of Anti-GBM Disease: Clues to an Environmental Trigger?

McAdoo SP, Pusey CD.

Clin J Am Soc Nephrol. 2016 Aug 8;11(8):1324-6. doi: 10.2215/CJN.05580516. Epub 2016 Jul 11. No abstract available.


IgA1 Glycosylation Is Heritable in Healthy Twins.

Lomax-Browne HJ, Visconti A, Pusey CD, Cook HT, Spector TD, Pickering MC, Falchi M.

J Am Soc Nephrol. 2017 Jan;28(1):64-68. doi: 10.1681/ASN.2016020184. Epub 2016 Jun 16.


The natural history of immunoglobulin M nephropathy in adults.

Connor TM, Aiello V, Griffith M, Cairns T, Roufosse CA, Cook HT, Pusey CD.

Nephrol Dial Transplant. 2017 May 1;32(5):823-829. doi: 10.1093/ndt/gfw063.


Ofatumumab for B cell depletion therapy in ANCA-associated vasculitis: a single-centre case series.

McAdoo SP, Bedi R, Tarzi R, Griffith M, Pusey CD, Cairns TD.

Rheumatology (Oxford). 2016 Aug;55(8):1437-42. doi: 10.1093/rheumatology/kew199. Epub 2016 Apr 19.


A novel method for high-throughput detection and quantification of neutrophil extracellular traps reveals ROS-independent NET release with immune complexes.

Kraaij T, Tengström FC, Kamerling SW, Pusey CD, Scherer HU, Toes RE, Rabelink TJ, van Kooten C, Teng YK.

Autoimmun Rev. 2016 Jun;15(6):577-84. doi: 10.1016/j.autrev.2016.02.018. Epub 2016 Feb 27. Review.


Human Chorionic Stem Cells: Podocyte Differentiation and Potential for the Treatment of Alport Syndrome.

Moschidou D, Corcelli M, Hau KL, Ekwalla VJ, Behmoaras JV, De Coppi P, David AL, Bou-Gharios G, Cook HT, Pusey CD, Fisk NM, Guillot PV.

Stem Cells Dev. 2016 Mar 1;25(5):395-404. doi: 10.1089/scd.2015.0305. Epub 2016 Feb 18.


Esophageal vasculitis in granulomatosis with polyangiitis.

Alexander S, Simon EG, Burad D, Varughese S, David VG, Jacob S, Sudhakar G, Tamilarasi V, Jacob CK, Pusey CD.

Trop Gastroenterol. 2015 Apr-Jun;36(2):132-4. No abstract available.


Occam's razor or Hickam's dictum? Allergic bronchopulmonary aspergillosis and eosinophilic granulomatosis with polyangiitis.

Henderson SR, Shah A, Copley SJ, Cook HT, Pusey CD, Salama AD, Ind PW.

Thorax. 2016 Feb;71(2):193-5. doi: 10.1136/thoraxjnl-2015-207280. Epub 2015 Dec 23. No abstract available.


Clinical and Imaging Features of Lacrimal Gland Involvement in Granulomatosis with Polyangiitis.

Tan LT, Davagnanam I, Isa H, Rose GE, Verity DH, Pusey CD, Lightman S.

Ophthalmology. 2015 Oct;122(10):2125-9. doi: 10.1016/j.ophtha.2015.06.026. Epub 2015 Jul 30.


Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.

Thiele M, Kerschbaumer RJ, Tam FW, Völkel D, Douillard P, Schinagl A, Kühnel H, Smith J, McDaid JP, Bhangal G, Yu MC, Pusey CD, Cook HT, Kovarik J, Magelky E, Bhan A, Rieger M, Mudde GC, Ehrlich H, Jilma B, Tilg H, Moschen A, Terhorst C, Scheiflinger F.

J Immunol. 2015 Sep 1;195(5):2343-52. doi: 10.4049/jimmunol.1500572. Epub 2015 Jul 24.


Outcome and treatment of elderly patients with ANCA-associated vasculitis.

Weiner M, Goh SM, Mohammad AJ, Hruskova Z, Tanna A, Bruchfeld A, Selga D, Chocova Z, Westman K, Eriksson P, Pusey CD, Tesar V, Salama AD, Segelmark M.

Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1128-35. doi: 10.2215/CJN.00480115. Epub 2015 Jun 22.


Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by 'autoantigen complementarity'.

Reynolds J, Preston GA, Pressler BM, Hewins P, Brown M, Roth A, Alderman E, Bunch D, Jennette JC, Cook HT, Falk RJ, Pusey CD.

J Autoimmun. 2015 May;59:8-18. doi: 10.1016/j.jaut.2015.01.003. Epub 2015 Apr 2.


Macrophage epoxygenase determines a profibrotic transcriptome signature.

Behmoaras J, Diaz AG, Venda L, Ko JH, Srivastava P, Montoya A, Faull P, Webster Z, Moyon B, Pusey CD, Abraham DJ, Petretto E, Cook TH, Aitman TJ.

J Immunol. 2015 May 15;194(10):4705-4716. doi: 10.4049/jimmunol.1402979. Epub 2015 Apr 3.


CD14 expression is increased on monocytes in patients with anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis and correlates with the expression of ANCA autoantigens.

Tarzi RM, Liu J, Schneiter S, Hill NR, Page TH, Cook HT, Pusey CD, Woollard KJ.

Clin Exp Immunol. 2015 Jul;181(1):65-75. doi: 10.1111/cei.12625.


S100A8/A9 (calprotectin) is critical for development of glomerulonephritis and promotes inflammatory leukocyte-renal cell interactions.

Pepper RJ, Wang HH, Rajakaruna GK, Papakrivopoulou E, Vogl T, Pusey CD, Cook HT, Salama AD.

Am J Pathol. 2015 May;185(5):1264-74. doi: 10.1016/j.ajpath.2015.01.015. Epub 2015 Mar 7.


Long-term Outcomes of Rituximab Therapy in Ocular Granulomatosis with Polyangiitis: Impact on Localized and Nonlocalized Disease.

Joshi L, Tanna A, McAdoo SP, Medjeral-Thomas N, Taylor SR, Sandhu G, Tarzi RM, Pusey CD, Lightman S.

Ophthalmology. 2015 Jun;122(6):1262-8. doi: 10.1016/j.ophtha.2015.01.016. Epub 2015 Mar 4.


Correlation of disease activity in proliferative glomerulonephritis with glomerular spleen tyrosine kinase expression.

McAdoo SP, Bhangal G, Page T, Cook HT, Pusey CD, Tam FW.

Kidney Int. 2015 Jul;88(1):52-60. doi: 10.1038/ki.2015.29. Epub 2015 Feb 25.


Prolonged B cell depletion with rituximab is effective in treating refractory pulmonary granulomatous inflammation in granulomatosis with polyangiitis (GPA).

Henderson SR, Copley SJ, Pusey CD, Ind PW, Salama AD.

Medicine (Baltimore). 2014 Dec;93(27):e229. doi: 10.1097/MD.0000000000000229.


Necrotizing and crescentic glomerulonephritis presenting with preserved renal function in patients with underlying multisystem autoimmune disease: a retrospective case series.

McAdoo SP, Tanna A, Randone O, Tam FW, Tarzi RM, Levy JB, Griffith M, Lightstone L, Cook HT, Cairns T, Pusey CD.

Rheumatology (Oxford). 2015 Jun;54(6):1025-32. doi: 10.1093/rheumatology/keu445. Epub 2014 Nov 26.


Renal function and ear, nose, throat involvement in anti-neutrophil cytoplasmic antibody-associated vasculitis: prospective data from the European Vasculitis Society clinical trials.

Rahmattulla C, de Lind van Wijngaarden RA, Berden AE, Hauer HA, Floßmann O, Jayne DR, Gaskin G, Rasmussen N, Noël LH, Ferrario F, Waldherr R, Wolterbeek R, Göçeroğlu A, Pusey CD, Hagen EC, Bruijn JA, Bajema IM; European Vasculitis Study Group (EUVAS).

Rheumatology (Oxford). 2015 May;54(5):899-907. doi: 10.1093/rheumatology/keu357. Epub 2014 Oct 22.


Successful outcome of pregnancy in patients with anti-neutrophil cytoplasm antibody-associated small vessel vasculitis.

Croft AP, Smith SW, Carr S, Youssouf S, Salama AD, Burns A, Pusey CD, Hamilton P, Brown N, Venning M, Harper L, Morgan MD.

Kidney Int. 2015 Apr;87(4):807-11. doi: 10.1038/ki.2014.329. Epub 2014 Oct 1.


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