Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 31

1.

Genome Sequences of RIGVIR Oncolytic Virotherapy Virus and Five Other Echovirus 7 Isolates.

Hietanen E, Smura T, Hakanen M, Chansaenroj J, Merilahti P, Nevalainen J, Pandey S, Koskinen S, Tripathi L, Poovorawan Y, Pursiheimo J, Susi P.

Genome Announc. 2018 Apr 26;6(17). pii: e00317-18. doi: 10.1128/genomeA.00317-18.

2.

Early fecal microbiota composition in children who later develop celiac disease and associated autoimmunity.

Rintala A, Riikonen I, Toivonen A, Pietilä S, Munukka E, Pursiheimo JP, Elo LL, Arikoski P, Luopajärvi K, Schwab U, Uusitupa M, Heinonen S, Savilahti E, Eerola E, Ilonen J.

Scand J Gastroenterol. 2018 Apr;53(4):403-409. doi: 10.1080/00365521.2018.1444788. Epub 2018 Mar 5.

PMID:
29504486
3.

A novel double nucleotide variant in the ferritin-L iron-responsive element in a Finnish patient with hereditary hyperferritinaemia-cataract syndrome.

Mattila RM, Sainio A, Järveläinen M, Pursiheimo J, Järveläinen H.

Acta Ophthalmol. 2018 Feb;96(1):95-99. doi: 10.1111/aos.13492. Epub 2017 Jun 21.

PMID:
28636169
4.

Gut Microbiota Analysis Results Are Highly Dependent on the 16S rRNA Gene Target Region, Whereas the Impact of DNA Extraction Is Minor.

Rintala A, Pietilä S, Munukka E, Eerola E, Pursiheimo JP, Laiho A, Pekkala S, Huovinen P.

J Biomol Tech. 2017 Apr;28(1):19-30. doi: 10.7171/jbt.17-2801-003. Epub 2017 Feb 28.

5.

Aging and serum exomiR content in women-effects of estrogenic hormone replacement therapy.

Kangas R, Törmäkangas T, Fey V, Pursiheimo J, Miinalainen I, Alen M, Kaprio J, Sipilä S, Säämänen AM, Kovanen V, Laakkonen EK.

Sci Rep. 2017 Feb 14;7:42702. doi: 10.1038/srep42702.

6.

Next generation sequencing of all variable loops of synthetic single framework scFv-Application in anti-HDL antibody selections.

Lövgren J, Pursiheimo JP, Pyykkö M, Salmi J, Lamminmäki U.

N Biotechnol. 2016 Dec 25;33(6):790-796. doi: 10.1016/j.nbt.2016.07.009. Epub 2016 Jul 19.

PMID:
27450754
7.

Neuropeptide Y Overexpressing Female and Male Mice Show Divergent Metabolic but Not Gut Microbial Responses to Prenatal Metformin Exposure.

Salomäki-Myftari H, Vähätalo LH, Ailanen L, Pietilä S, Laiho A, Hänninen A, Pursiheimo JP, Munukka E, Rintala A, Savontaus E, Pesonen U, Koulu M.

PLoS One. 2016 Sep 28;11(9):e0163805. doi: 10.1371/journal.pone.0163805. eCollection 2016.

8.

Detection of Novel Gene Variants Associated with Congenital Hypothyroidism in a Finnish Patient Cohort.

Löf C, Patyra K, Kuulasmaa T, Vangipurapu J, Undeutsch H, Jaeschke H, Pajunen T, Kero A, Krude H, Biebermann H, Kleinau G, Kühnen P, Rantakari K, Miettinen P, Kirjavainen T, Pursiheimo JP, Mustila T, Jääskeläinen J, Ojaniemi M, Toppari J, Ignatius J, Laakso M, Kero J.

Thyroid. 2016 Sep;26(9):1215-24. doi: 10.1089/thy.2016.0016. Epub 2016 Aug 2.

9.

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.

Natunen T, Takalo M, Kemppainen S, Leskelä S, Marttinen M, Kurkinen KMA, Pursiheimo JP, Sarajärvi T, Viswanathan J, Gabbouj S, Solje E, Tahvanainen E, Pirttimäki T, Kurki M, Paananen J, Rauramaa T, Miettinen P, Mäkinen P, Leinonen V, Soininen H, Airenne K, Tanzi RE, Tanila H, Haapasalo A, Hiltunen M.

Neurobiol Dis. 2016 Jan;85:187-205. doi: 10.1016/j.nbd.2015.11.005. Epub 2015 Nov 10.

PMID:
26563932
10.

The Expression of Transthyretin and Amyloid-β Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.

Laiterä T, Kurki MI, Pursiheimo JP, Zetterberg H, Helisalmi S, Rauramaa T, Alafuzoff I, Remes AM, Soininen H, Haapasalo A, Jääskeläinen JE, Hiltunen M, Leinonen V.

J Alzheimers Dis. 2015;48(4):959-68. doi: 10.3233/JAD-150268.

PMID:
26444765
11.

An effective combination of sanger and next generation sequencing in diagnostics of primary ciliary dyskinesia.

Djakow J, Kramná L, Dušátková L, Uhlík J, Pursiheimo JP, Svobodová T, Pohunek P, Cinek O.

Pediatr Pulmonol. 2016 May;51(5):498-509. doi: 10.1002/ppul.23261. Epub 2015 Jul 30.

PMID:
26228299
12.

Gut virome sequencing in children with early islet autoimmunity.

Kramná L, Kolářová K, Oikarinen S, Pursiheimo JP, Ilonen J, Simell O, Knip M, Veijola R, Hyöty H, Cinek O.

Diabetes Care. 2015 May;38(5):930-3. doi: 10.2337/dc14-2490. Epub 2015 Feb 12.

PMID:
25678103
13.

Genome Sequence of Coxsackievirus A6, Isolated during a Hand-Foot-and-Mouth Disease Outbreak in Finland in 2008.

Osterback R, Koskinen S, Merilahti P, Pursiheimo JP, Blomqvist S, Roivainen M, Laiho A, Susi P, Waris M.

Genome Announc. 2014 Oct 16;2(5). pii: e01004-14. doi: 10.1128/genomeA.01004-14.

14.

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.

Martiskainen H, Viswanathan J, Nykänen NP, Kurki M, Helisalmi S, Natunen T, Sarajärvi T, Kurkinen KM, Pursiheimo JP, Rauramaa T, Alafuzoff I, Jääskeläinen JE, Leinonen V, Soininen H, Haapasalo A, Huttunen HJ, Hiltunen M.

Neurobiol Aging. 2015 Feb;36(2):1221.e15-28. doi: 10.1016/j.neurobiolaging.2014.09.003. Epub 2014 Sep 6.

PMID:
25281018
15.

Fermentable fibres condition colon microbiota and promote diabetogenesis in NOD mice.

Toivonen RK, Emani R, Munukka E, Rintala A, Laiho A, Pietilä S, Pursiheimo JP, Soidinsalo P, Linhala M, Eerola E, Huovinen P, Hänninen A.

Diabetologia. 2014 Oct;57(10):2183-92. doi: 10.1007/s00125-014-3325-6. Epub 2014 Jul 17.

PMID:
25031069
16.

Promoter-specific alterations of APC are a rare cause for mutation-negative familial adenomatous polyposis.

Pavicic W, Nieminen TT, Gylling A, Pursiheimo JP, Laiho A, Gyenesei A, Järvinen HJ, Peltomäki P.

Genes Chromosomes Cancer. 2014 Oct;53(10):857-64. doi: 10.1002/gcc.22197. Epub 2014 Jun 20.

PMID:
24946964
17.

Gene expression differences between Noccaea caerulescens ecotypes help to identify candidate genes for metal phytoremediation.

Halimaa P, Lin YF, Ahonen VH, Blande D, Clemens S, Gyenesei A, Häikiö E, Kärenlampi SO, Laiho A, Aarts MG, Pursiheimo JP, Schat H, Schmidt H, Tuomainen MH, Tervahauta AI.

Environ Sci Technol. 2014 Mar 18;48(6):3344-53. doi: 10.1021/es4042995. Epub 2014 Mar 6.

PMID:
24559272
18.

Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease.

Natunen T, Martiskainen H, Sarajärvi T, Helisalmi S, Pursiheimo JP, Viswanathan J, Laitinen M, Mäkinen P, Kauppinen T, Rauramaa T, Leinonen V, Alafuzoff I, Haapasalo A, Soininen H, Hiltunen M.

PLoS One. 2013 Nov 20;8(11):e80700. doi: 10.1371/journal.pone.0080700. eCollection 2013.

19.

Continuous hypoxic culturing of human embryonic stem cells enhances SSEA-3 and MYC levels.

Närvä E, Pursiheimo JP, Laiho A, Rahkonen N, Emani MR, Viitala M, Laurila K, Sahla R, Lund R, Lähdesmäki H, Jaakkola P, Lahesmaa R.

PLoS One. 2013 Nov 13;8(11):e78847. doi: 10.1371/journal.pone.0078847. eCollection 2013.

20.

Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease.

Natunen T, Parrado AR, Helisalmi S, Pursiheimo JP, Sarajärvi T, Mäkinen P, Kurkinen KM, Mullin K, Alafuzoff I, Haapasalo A, Bertram L, Soininen H, Tanzi RE, Hiltunen M.

J Alzheimers Dis. 2013;37(1):217-32. doi: 10.3233/JAD-130104.

PMID:
23970038
21.

p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation.

Rantanen K, Pursiheimo JP, Högel H, Miikkulainen P, Sundström J, Jaakkola PM.

J Cell Sci. 2013 Mar 1;126(Pt 5):1144-54. doi: 10.1242/jcs.115667. Epub 2013 Jan 23.

22.

Expression of small nucleolar RNAs in leukemic cells.

Teittinen KJ, Laiho A, Uusimäki A, Pursiheimo JP, Gyenesei A, Lohi O.

Cell Oncol (Dordr). 2013 Feb;36(1):55-63. doi: 10.1007/s13402-012-0113-5. Epub 2012 Nov 15.

PMID:
23229394
23.

Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells.

Benson MJ, Aijö T, Chang X, Gagnon J, Pape UJ, Anantharaman V, Aravind L, Pursiheimo JP, Oberdoerffer S, Liu XS, Lahesmaa R, Lähdesmäki H, Rao A.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16252-7. doi: 10.1073/pnas.1214414109. Epub 2012 Sep 18.

24.

GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients.

Kämäläinen A, Viswanathan J, Natunen T, Helisalmi S, Kauppinen T, Pikkarainen M, Pursiheimo JP, Alafuzoff I, Kivipelto M, Haapasalo A, Soininen H, Herukka SK, Hiltunen M.

J Alzheimers Dis. 2013;33(1):23-7. doi: 10.3233/JAD-2012-120946.

PMID:
22890097
25.

RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation.

Närvä E, Rahkonen N, Emani MR, Lund R, Pursiheimo JP, Nästi J, Autio R, Rasool O, Denessiouk K, Lähdesmäki H, Rao A, Lahesmaa R.

Stem Cells. 2012 Mar;30(3):452-60. doi: 10.1002/stem.1013.

26.

p62 degradation by autophagy: another way for cancer cells to survive under hypoxia.

Jaakkola PM, Pursiheimo JP.

Autophagy. 2009 Apr;5(3):410-2. Epub 2009 Apr 16.

PMID:
19197142
27.

Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62.

Pursiheimo JP, Rantanen K, Heikkinen PT, Johansen T, Jaakkola PM.

Oncogene. 2009 Jan 22;28(3):334-44. doi: 10.1038/onc.2008.392. Epub 2008 Oct 20.

PMID:
18931699
28.

Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation.

Rantanen K, Pursiheimo J, Högel H, Himanen V, Metzen E, Jaakkola PM.

Mol Biol Cell. 2008 May;19(5):2231-40. doi: 10.1091/mbc.E07-11-1124. Epub 2008 Mar 12.

29.

Protein kinase A balances the growth factor-induced Ras/ERK signaling.

Pursiheimo JP, Kieksi A, Jalkanen M, Salmivirta M.

FEBS Lett. 2002 Jun 19;521(1-3):157-64.

30.
31.

Involvement of protein kinase A in fibroblast growth factor-2-activated transcription.

Pursiheimo JP, Jalkanen M, Taskén K, Jaakkola P.

Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):168-73.

Supplemental Content

Loading ...
Support Center