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Items: 34

1.

Genotoxicity of two new carbazole derivatives with antifungal activity.

Zhanataev AK, Eremina NV, Chayka ZV, Kazey VI, Andrianova EL, Purmal AA, Rydkina EB, Durnev AD.

Mutat Res Genet Toxicol Environ Mutagen. 2017 Apr;816-817:24-31. doi: 10.1016/j.mrgentox.2017.03.004. Epub 2017 Apr 1.

PMID:
28464993
2.

Preclinical Validation of a Single-Treatment Infusion Modality That Can Eradicate Extremity Melanomas.

Kim M, Neznanov N, Wilfong CD, Fleyshman DI, Purmal AA, Haderski G, Stanhope-Baker P, Burkhart CA, Gurova KV, Gudkov AV, Skitzki JJ.

Cancer Res. 2016 Nov 15;76(22):6620-6630. doi: 10.1158/0008-5472.CAN-15-2764. Epub 2016 Sep 28.

3.

Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma.

Barone TA, Burkhart CA, Safina A, Haderski G, Gurova KV, Purmal AA, Gudkov AV, Plunkett RJ.

Neuro Oncol. 2017 Feb 1;19(2):186-196. doi: 10.1093/neuonc/now141.

4.

Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models.

Dermawan JK, Hitomi M, Silver DJ, Wu Q, Sandlesh P, Sloan AE, Purmal AA, Gurova KV, Rich JN, Lathia JD, Stark GR, Venere M.

Cancer Res. 2016 Apr 15;76(8):2432-42. doi: 10.1158/0008-5472.CAN-15-2162. Epub 2016 Feb 26.

5.

The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates.

Krivokrysenko VI, Toshkov IA, Gleiberman AS, Krasnov P, Shyshynova I, Bespalov I, Maitra RK, Narizhneva NV, Singh VK, Whitnall MH, Purmal AA, Shakhov AN, Gudkov AV, Feinstein E.

PLoS One. 2015 Sep 14;10(9):e0135388. doi: 10.1371/journal.pone.0135388. eCollection 2015.

6.

Targeting FACT complex suppresses mammary tumorigenesis in Her2/neu transgenic mice.

Koman IE, Commane M, Paszkiewicz G, Hoonjan B, Pal S, Safina A, Toshkov I, Purmal AA, Wang D, Liu S, Morrison C, Gudkov AV, Gurova KV.

Cancer Prev Res (Phila). 2012 Aug;5(8):1025-35. doi: 10.1158/1940-6207.CAPR-11-0529. Epub 2012 Jun 11.

7.

Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT.

Gasparian AV, Burkhart CA, Purmal AA, Brodsky L, Pal M, Saranadasa M, Bosykh DA, Commane M, Guryanova OA, Pal S, Safina A, Sviridov S, Koman IE, Veith J, Komar AA, Gudkov AV, Gurova KV.

Sci Transl Med. 2011 Aug 10;3(95):95ra74. doi: 10.1126/scitranslmed.3002530.

8.

Small molecule screening reveals a transcription-independent pro-survival function of androgen receptor in castration-resistant prostate cancer.

Narizhneva NV, Tararova ND, Ryabokon P, Shyshynova I, Prokvolit A, Komarov PG, Purmal AA, Gudkov AV, Gurova KV.

Cell Cycle. 2009 Dec 15;8(24):4155-67. Epub 2009 Dec 13.

9.

Fabs specific for 8-oxoguanine: control of DNA binding.

Bespalov IA, Bond JP, Purmal AA, Wallace SS, Melamede RJ.

J Mol Biol. 1999 Nov 12;293(5):1085-95.

PMID:
10547287
10.

Enzymatic processing of uracil glycol, a major oxidative product of DNA cytosine.

Purmal AA, Lampman GW, Bond JP, Hatahet Z, Wallace SS.

J Biol Chem. 1998 Apr 17;273(16):10026-35.

11.

Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII.

Harrison L, Hatahet Z, Purmal AA, Wallace SS.

Nucleic Acids Res. 1998 Feb 15;26(4):932-41.

12.
13.
14.

A common mechanism of action for the N-glycosylase activity of DNA N-glycosylase/AP lyases from E. coli and T4.

Purmal AA, Rabow LE, Lampman GW, Cunningham RP, Kow YW.

Mutat Res. 1996 Dec 2;364(3):193-207.

PMID:
8960131
15.

Recombinant Phabs reactive with 7,8-dihydro-8-oxoguanine, a major oxidative DNA lesion.

Bespalov IA, Purmal AA, Glackin MP, Wallace SS, Melamede RJ.

Biochemistry. 1996 Feb 20;35(7):2067-78.

PMID:
8652548
17.

Uracil DNA N-glycosylase distributively interacts with duplex polynucleotides containing repeating units of either TGGCCAAGCU or TGGCCAAGCTTGGCCAAGCU.

Purmal AA, Lampman GW, Pourmal EI, Melamede RJ, Wallace SS, Kow YW.

J Biol Chem. 1994 Sep 2;269(35):22046-53.

18.

The sequence context-dependent mispairing of 5-hydroxycytosine and 5-hydroxyuridine in vitro.

Purmal AA, Lampman GW, Kow YW, Wallace SS.

Ann N Y Acad Sci. 1994 Jul 29;726:361-3. No abstract available.

PMID:
8092705
19.

Oxidative DNA lesions as blocks to in vitro transcription by phage T7 RNA polymerase.

Hatahet Z, Purmal AA, Wallace SS.

Ann N Y Acad Sci. 1994 Jul 29;726:346-8. Review. No abstract available.

PMID:
8092701
21.

Alpha-deoxyadenosine, a major anoxic radiolysis product of adenine in DNA, is a substrate for Escherichia coli endonuclease IV.

Ide H, Tedzuka K, Shimzu H, Kimura Y, Purmal AA, Wallace SS, Kow YW.

Biochemistry. 1994 Jun 28;33(25):7842-7.

PMID:
7516707
23.
25.

[Study of the mutagenic properties of oligonucleotides containing and internucleotide pyrophosphate bond using a mutation system based on phage M13].

Petrenko VA, Kuz'micheva GA, Tat'kov SI, Krasnoborov II, Il'ichev AA, Drutsa VL, Purmal' AA, Shabarova ZA.

Mol Biol (Mosk). 1991 Nov-Dec;25(6):1539-45. Russian.

PMID:
1667540
26.

[Hybridase cleavage of RNA. I. Oligonucleotide probes for regiospecific RNA cleavage].

Metelev VG, Krynetskaia NF, Purmal' AA, Shabarova ZA.

Bioorg Khim. 1990 Apr;16(4):507-13. Russian.

PMID:
1695848
27.

[Introduction of tri- and tetraphosphate internucleotide bonds into oligodeoxyribonucleotides].

Purmal' AA, Drutsa VL, Shabarova ZA.

Bioorg Khim. 1988 Sep;14(9):1183-7. Russian.

PMID:
3219134
28.

[Transfer of "artificial transposons" constructed on the basis of insertion element IS1].

Mirkin SM, Bass IA, Kacherovskaia NA, Purmal' AA, Oretskaia TS.

Genetika. 1987 May;23(5):757-65. Russian.

PMID:
3040525
29.
30.

[A new type of DNA modification. Specific introduction of 3'-5'-pyrophosphate internucleotide bonds].

Purmal' AA, Drutsa VL, Shabarova ZA.

Bioorg Khim. 1984 Mar;10(3):394-400. Russian.

PMID:
6091683
31.

[Interaction of EcoRII restriction and modification enzymes with DNA duplexes containing pyrophosphate bonds].

Purmal' AA, Vinogradova MN, Elov AA, Gromova ES, Drutsa VL.

Dokl Akad Nauk SSSR. 1984;276(4):992-5. Russian. No abstract available.

PMID:
6088201
32.

[DNA-like duplexes containing repetitions. V. Chemical template synthesis of polynucleotides containing 3',5'-pyrophosphate internucleotide bonds].

Purmal' AA, Drutsa VL, Ivanovskaia MG, Shabarova ZA, Prokof'ev MA.

Dokl Akad Nauk SSSR. 1982;265(1):242-5. Russian. No abstract available.

PMID:
6286263
33.

DNA-like duplexes with repetitions. III. Efficient template-guided chemical polymerization of d(TGGCCAAGCTp).

Shabarova ZA, Dolinnaya NG, Drutsa VL, Melnikova NP, Purmal AA.

Nucleic Acids Res. 1981 Nov 11;9(21):5747-61.

34.

[Synthesis of photoaffinity reagents octadesoxyribonucleotide derived of the complementary portion of the 3'-terminal fragment of 16S rRNA of Escherichia coli ribosomes].

Krynetskii EIu, Ivanovskaia MG, Drutsa VL, Purmal' AA, Sokolova NI.

Dokl Akad Nauk SSSR. 1979;247(3):752-4. Russian. No abstract available.

PMID:
383432

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