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Items: 24

1.

Retargeted clostridial endopeptidases: inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain.

Chaddock JA, Purkiss JR, Alexander FC, Doward S, Fooks SJ, Friis LM, Hall YH, Kirby ER, Leeds N, Moulsdale HJ, Dickenson A, Green GM, Rahman W, Suzuki R, Duggan MJ, Quinn CP, Shone CC, Foster KA.

Mov Disord. 2004 Mar;19 Suppl 8:S42-7.

PMID:
15027053
2.

Inhibition of release of neurotransmitters from rat dorsal root ganglia by a novel conjugate of a Clostridium botulinum toxin A endopeptidase fragment and Erythrina cristagalli lectin.

Duggan MJ, Quinn CP, Chaddock JA, Purkiss JR, Alexander FC, Doward S, Fooks SJ, Friis LM, Hall YH, Kirby ER, Leeds N, Moulsdale HJ, Dickenson A, Green GM, Rahman W, Suzuki R, Shone CC, Foster KA.

J Biol Chem. 2002 Sep 20;277(38):34846-52. Epub 2002 Jul 8.

3.

Clostridium botulinum neurotoxins act with a wide range of potencies on SH-SY5Y human neuroblastoma cells.

Purkiss JR, Friis LM, Doward S, Quinn CP.

Neurotoxicology. 2001 Aug;22(4):447-53.

PMID:
11577803
4.
5.

Inhibition of vesicular secretion in both neuronal and nonneuronal cells by a retargeted endopeptidase derivative of Clostridium botulinum neurotoxin type A.

Chaddock JA, Purkiss JR, Friis LM, Broadbridge JD, Duggan MJ, Fooks SJ, Shone CC, Quinn CP, Foster KA.

Infect Immun. 2000 May;68(5):2587-93.

6.

Sensitivity of embryonic rat dorsal root ganglia neurons to Clostridium botulinum neurotoxins.

Welch MJ, Purkiss JR, Foster KA.

Toxicon. 2000 Feb;38(2):245-58.

PMID:
10665805
7.

A method for the measurement of [3H]-glutamate release from cultured dorsal root ganglion neurons.

Purkiss JR, Welch MJ, Doward S, Foster KA, Quinn CP.

Biochem Soc Trans. 1998 May;26(2):S108. No abstract available.

PMID:
9649783
8.

Capsaicin stimulates release of substance P from dorsal root ganglion neurons via two distinct mechanisms.

Purkiss JR, Welch MJ, Doward S, Foster KA.

Biochem Soc Trans. 1997 Aug;25(3):542S. No abstract available.

PMID:
9388756
10.

Protein kinase C modulation of phosphoinositidase C in 1321N1 human astrocytoma cells.

Purkiss JR.

Biochem Soc Trans. 1996 Feb;24(1):54S. No abstract available.

PMID:
8674728
11.

Activation of phospholipase D in SH-SY5Y neuroblastoma cells: dependence on Ca2+ and protein kinase C.

Purkiss JR.

Biochem Soc Trans. 1995 Aug;23(3):427S. No abstract available.

PMID:
8566315
13.

Measurement of diacylglycerol. Origins of receptor-stimulated diacylglycerol accumulation.

Boarder MR, Purkiss JR.

Methods Mol Biol. 1995;41:189-202. No abstract available.

PMID:
7655556
14.

Phospholipase D does not mediate alcohol inhibition of [3H]-noradrenaline release from SH-SY5Y cells.

Purkiss JR.

Biochem Soc Trans. 1994 Nov;22(4):419S. No abstract available.

PMID:
7698439
15.

Mobilisation of intracellular Ca2+ triggers [3H]-noradrenaline release from SH-SY5Y cells.

Purkiss JR, Willars GB, Nahorski SR.

Biochem Soc Trans. 1994 Nov;22(4):417S. No abstract available.

PMID:
7698437
17.

Stimulation of phospholipase C in cultured microvascular endothelial cells from human frontal lobe by histamine, endothelin and purinoceptor agonists.

Purkiss JR, West D, Wilkes LC, Scott C, Yarrow P, Wilkinson GF, Boarder MR.

Br J Pharmacol. 1994 Apr;111(4):1041-6.

19.

Phospholipase D activation regulates endothelin-1 stimulation of phosphoinositide-specific phospholipase C in SK-N-MC cells.

Challiss RA, Wilkes LC, Patel V, Purkiss JR, Boarder MR.

FEBS Lett. 1993 Jul 26;327(2):157-60.

21.
24.

Purinergic stimulation of phosphatidic acid accumulation is via two pathways in bovine aorta endothelial cells.

Purkiss JR, Boarder MR.

Biochem Soc Trans. 1992 May;20(2):141S. No abstract available.

PMID:
1397535

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