Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 50

1.

A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing.

Hassan S, Purdie KJ, Wang J, Harwood CA, Proby CM, Pourreyron C, Mladkova N, Nagano A, Dhayade S, Athineos D, Caley M, Mannella V, Blyth K, Inman GJ, Leigh IM.

Int J Mol Sci. 2019 Jul 12;20(14). pii: E3428. doi: 10.3390/ijms20143428.

2.

Epigenetic Regulation of iASPP-p63 Feedback Loop in Cutaneous Squamous Cell Carcinoma.

Robinson DJ, Patel A, Purdie KJ, Wang J, Rizvi H, Hufbauer M, Ostano P, Akgül B, Chiorino G, Harwood CA, Bergamaschi D.

J Invest Dermatol. 2019 Aug;139(8):1658-1671.e8. doi: 10.1016/j.jid.2019.01.020. Epub 2019 Jan 30.

PMID:
30710576
3.

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.

Inman GJ, Wang J, Nagano A, Alexandrov LB, Purdie KJ, Taylor RG, Sherwood V, Thomson J, Hogan S, Spender LC, South AP, Stratton M, Chelala C, Harwood CA, Proby CM, Leigh IM.

Nat Commun. 2018 Sep 10;9(1):3667. doi: 10.1038/s41467-018-06027-1.

4.

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions.

Purdie KJ, Proby CM, Rizvi H, Griffin H, Doorbar J, Sommerlad M, Feltkamp MC, der Meijden EV, Inman GJ, South AP, Leigh IM, Harwood CA.

Front Microbiol. 2018 Aug 14;9:1806. doi: 10.3389/fmicb.2018.01806. eCollection 2018.

5.

Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma.

Rose AM, Spender LC, Stephen C, Mitchell A, Rickaby W, Bray S, Evans AT, Dayal J, Purdie KJ, Harwood CA, Proby CM, Leigh IM, Coates PJ, Inman GJ.

Oncotarget. 2018 Feb 22;9(18):14552-14566. doi: 10.18632/oncotarget.24545. eCollection 2018 Mar 6.

6.

Genomic analysis of atypical fibroxanthoma.

Lai K, Harwood CA, Purdie KJ, Proby CM, Leigh IM, Ravi N, Mully TW, Brooks L, Sandoval PM, Rosenblum MD, Arron ST.

PLoS One. 2017 Nov 15;12(11):e0188272. doi: 10.1371/journal.pone.0188272. eCollection 2017.

7.

Whole-Exome Sequencing Validates a Preclinical Mouse Model for the Prevention and Treatment of Cutaneous Squamous Cell Carcinoma.

Knatko EV, Praslicka B, Higgins M, Evans A, Purdie KJ, Harwood CA, Proby CM, Ooi A, Dinkova-Kostova AT.

Cancer Prev Res (Phila). 2017 Jan;10(1):67-75. doi: 10.1158/1940-6207.CAPR-16-0218. Epub 2016 Dec 6.

8.

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma.

Cammareri P, Rose AM, Vincent DF, Wang J, Nagano A, Libertini S, Ridgway RA, Athineos D, Coates PJ, McHugh A, Pourreyron C, Dayal JH, Larsson J, Weidlich S, Spender LC, Sapkota GP, Purdie KJ, Proby CM, Harwood CA, Leigh IM, Clevers H, Barker N, Karlsson S, Pritchard C, Marais R, Chelala C, South AP, Sansom OJ, Inman GJ.

Nat Commun. 2016 Aug 25;7:12493. doi: 10.1038/ncomms12493.

9.

CREBBP mutation in human cutaneous squamous cell carcinoma.

Watt SA, Purdie KJ, den Breems NY, Dimon M, Tucker S, Arron ST, McHugh A, Xue DJ, Dayal JH, Harwood CA, Leigh IM, Proby CM, South AP.

Exp Dermatol. 2016 Aug;25(8):650-1. doi: 10.1111/exd.13044. Epub 2016 Jun 30. No abstract available.

PMID:
27094574
10.

HLA Immunogenotype Determines Persistent Human Papillomavirus Virus Infection in HIV-Infected Patients Receiving Antiretroviral Treatment.

Meys R, Purdie KJ, de Koning MN, Quint KD, Little AM, Baker F, Francis N, Asboe D, Hawkins D, Marsh SG, Harwood CA, Gotch FM, Bunker CB.

J Infect Dis. 2016 Jun 1;213(11):1717-24. doi: 10.1093/infdis/jiw038. Epub 2016 Feb 9.

PMID:
26908737
11.

Novel CARD11 Mutations in Human Cutaneous Squamous Cell Carcinoma Lead to Aberrant NF-κB Regulation.

Watt SA, Purdie KJ, den Breems NY, Dimon M, Arron ST, McHugh AT, Xue DJ, Dayal JH, Proby CM, Harwood CA, Leigh IM, South AP.

Am J Pathol. 2015 Sep;185(9):2354-63. doi: 10.1016/j.ajpath.2015.05.018. Epub 2015 Jul 26.

12.

NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis.

South AP, Purdie KJ, Watt SA, Haldenby S, den Breems N, Dimon M, Arron ST, Kluk MJ, Aster JC, McHugh A, Xue DJ, Dayal JH, Robinson KS, Rizvi SH, Proby CM, Harwood CA, Leigh IM.

J Invest Dermatol. 2014 Oct;134(10):2630-2638. doi: 10.1038/jid.2014.154. Epub 2014 Mar 24.

13.

Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling.

Lambert SR, Mladkova N, Gulati A, Hamoudi R, Purdie K, Cerio R, Leigh I, Proby C, Harwood CA.

Br J Cancer. 2014 Jan 21;110(2):520-9. doi: 10.1038/bjc.2013.760. Epub 2013 Dec 12.

14.

The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas.

Leufke C, Leykauf J, Krunic D, Jauch A, Holtgreve-Grez H, Böhm-Steuer B, Bröcker EB, Mauch C, Utikal J, Hartschuh W, Purdie KJ, Boukamp P.

Oncogene. 2014 Jul 3;33(27):3506-18. doi: 10.1038/onc.2013.323. Epub 2013 Aug 19.

PMID:
23955078
15.

Exploiting FOXM1-orchestrated molecular network for early squamous cell carcinoma diagnosis and prognosis.

Teh MT, Hutchison IL, Costea DE, Neppelberg E, Liavaag PG, Purdie K, Harwood C, Wan H, Odell EW, Hackshaw A, Waseem A.

Int J Cancer. 2013 May 1;132(9):2095-106. doi: 10.1002/ijc.27886. Epub 2012 Oct 25.

16.

AKT1 loss correlates with episomal HPV16 in vulval intraepithelial neoplasia.

Ekeowa-Anderson AL, Purdie KJ, Gibbon K, Byrne CR, Arbeit JM, Harwood CA, O'Shaughnessy RF.

PLoS One. 2012;7(6):e38608. doi: 10.1371/journal.pone.0038608. Epub 2012 Jun 7.

17.

NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity.

Wang H, Lee S, Nigro CL, Lattanzio L, Merlano M, Monteverde M, Matin R, Purdie K, Mladkova N, Bergamaschi D, Harwood C, Syed N, Szlosarek P, Briasoulis E, McHugh A, Thompson A, Evans A, Leigh I, Fleming C, Inman GJ, Hatzimichael E, Proby C, Crook T.

Br J Cancer. 2012 Apr 10;106(8):1446-52. doi: 10.1038/bjc.2012.95. Epub 2012 Mar 27.

18.

Metastatic cutaneous squamous cell carcinoma shows frequent deletion in the protein tyrosine phosphatase receptor Type D gene.

Lambert SR, Harwood CA, Purdie KJ, Gulati A, Matin RN, Romanowska M, Cerio R, Kelsell DP, Leigh IM, Proby CM.

Int J Cancer. 2012 Aug 1;131(3):E216-26. doi: 10.1002/ijc.27333. Epub 2011 Dec 21.

19.

Clinically significant human papilloma virus in squamous cell carcinoma of the head and neck in UK practice.

Heath S, Willis V, Allan K, Purdie K, Harwood C, Shields P, Simcock R, Williams T, Gilbert DC.

Clin Oncol (R Coll Radiol). 2012 Feb;24(1):e18-23. doi: 10.1016/j.clon.2011.05.007. Epub 2011 Jul 14.

PMID:
21752613
20.

Cutaneous squamous cell carcinoma (SCC) and the DNA damage response: pATM expression patterns in pre-malignant and malignant keratinocyte skin lesions.

Ismail F, Ikram M, Purdie K, Harwood C, Leigh I, Storey A.

PLoS One. 2011;6(7):e21271. doi: 10.1371/journal.pone.0021271. Epub 2011 Jul 1.

21.

Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma.

Watt SA, Pourreyron C, Purdie K, Hogan C, Cole CL, Foster N, Pratt N, Bourdon JC, Appleyard V, Murray K, Thompson AM, Mao X, Mein C, Bruckner-Tuderman L, Evans A, McGrath JA, Proby CM, Foerster J, Leigh IM, South AP.

Oncogene. 2011 Nov 17;30(46):4666-77. doi: 10.1038/onc.2011.180. Epub 2011 May 23.

22.

Feeder layers: co-culture with nonneoplastic cells.

Pourreyron C, Purdie KJ, Watt SA, South AP.

Methods Mol Biol. 2011;731:467-70. doi: 10.1007/978-1-61779-080-5_37.

PMID:
21516429
23.

Isolation and culture of squamous cell carcinoma lines.

Purdie KJ, Pourreyron C, South AP.

Methods Mol Biol. 2011;731:151-9. doi: 10.1007/978-1-61779-080-5_14.

PMID:
21516406
24.

No evidence that human papillomavirus is responsible for the aggressive nature of recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma.

Purdie KJ, Pourreyron C, Fassihi H, Cepeda-Valdes R, Frew JW, Volz A, Weissenborn SJ, Pfister H, Proby CM, Bruckner-Tuderman L, Murrell DF, Salas-Alanis JC, McGrath JA, Leigh IM, Harwood CA, South AP.

J Invest Dermatol. 2010 Dec;130(12):2853-5. doi: 10.1038/jid.2010.243. Epub 2010 Aug 26. No abstract available.

25.

Evaluation of a novel broad-spectrum PCR-multiplex genotyping assay for identification of cutaneous wart-associated human papillomavirus types.

de Koning MN, ter Schegget J, Eekhof JA, Kamp M, Kleter B, Gussekloo J, Feltkamp MC, Bouwes Bavinck JN, Purdie KJ, Bunker CB, Proby CM, Meys R, Harwood CA, Quint WG.

J Clin Microbiol. 2010 May;48(5):1706-11. doi: 10.1128/JCM.02122-09. Epub 2010 Mar 17.

26.

High-resolution genomic profiling of human papillomavirus-associated vulval neoplasia.

Purdie KJ, Harwood CA, Gibbon K, Chaplin T, Young BD, Cazier JB, Singh N, Leigh IM, Proby CM.

Br J Cancer. 2010 Mar 16;102(6):1044-51. doi: 10.1038/sj.bjc.6605589.

27.

Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen.

Martins VL, Vyas JJ, Chen M, Purdie K, Mein CA, South AP, Storey A, McGrath JA, O'Toole EA.

J Cell Sci. 2009 Jun 1;122(Pt 11):1788-99. doi: 10.1242/jcs.042895. Epub 2009 May 12.

28.

Single nucleotide polymorphism array analysis defines a specific genetic fingerprint for well-differentiated cutaneous SCCs.

Purdie KJ, Harwood CA, Gulati A, Chaplin T, Lambert SR, Cerio R, Kelly GP, Cazier JB, Young BD, Leigh IM, Proby CM.

J Invest Dermatol. 2009 Jun;129(6):1562-8. doi: 10.1038/jid.2008.408. Epub 2009 Jan 8.

29.

Genital and cutaneous human papillomavirus (HPV) types in relation to conjunctival squamous cell neoplasia: a case-control study in Uganda.

de Koning MN, Waddell K, Magyezi J, Purdie K, Proby C, Harwood C, Lucas S, Downing R, Quint WG, Newton R.

Infect Agent Cancer. 2008 Sep 10;3:12. doi: 10.1186/1750-9378-3-12.

30.

Beta-papillomaviruses and psoriasis: an intra-patient comparison of human papillomavirus carriage in skin and hair.

Cronin JG, Mesher D, Purdie K, Evans H, Breuer J, Harwood CA, McGregor JM, Proby CM.

Br J Dermatol. 2008 Jul;159(1):113-9. doi: 10.1111/j.1365-2133.2008.08627.x. Epub 2008 Jul 1.

31.

Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis.

Purdie KJ, Lambert SR, Teh MT, Chaplin T, Molloy G, Raghavan M, Kelsell DP, Leigh IM, Harwood CA, Proby CM, Young BD.

Genes Chromosomes Cancer. 2007 Jul;46(7):661-9.

32.

A distinct variant of Epidermodysplasia verruciformis in a Turkish family lacking EVER1 and EVER2 mutations.

Akgül B, Köse O, Safali M, Purdie K, Cerio R, Proby C, Storey A.

J Dermatol Sci. 2007 Jun;46(3):214-6. Epub 2007 Feb 16. No abstract available.

33.

Are keratoacanthomas variants of squamous cell carcinomas? A comparison of chromosomal aberrations by comparative genomic hybridization.

Clausen OP, Aass HC, Beigi M, Purdie KJ, Proby CM, Brown VL, Mattingsdal M, Micci F, Kølvraa S, Bolund L, Deangelis PM.

J Invest Dermatol. 2006 Oct;126(10):2308-15. Epub 2006 May 25.

34.

Human papillomavirus gene expression in cutaneous squamous cell carcinomas from immunosuppressed and immunocompetent individuals.

Purdie KJ, Surentheran T, Sterling JC, Bell L, McGregor JM, Proby CM, Harwood CA, Breuer J.

J Invest Dermatol. 2005 Jul;125(1):98-107.

35.

Human papillomavirus-DNA loads in actinic keratoses exceed those in non-melanoma skin cancers.

Weissenborn SJ, Nindl I, Purdie K, Harwood C, Proby C, Breuer J, Majewski S, Pfister H, Wieland U.

J Invest Dermatol. 2005 Jul;125(1):93-7.

36.

Does human papillomavirus play a role in the development of bladder transitional cell carcinoma? A comparison of PCR and immunohistochemical analysis.

Youshya S, Purdie K, Breuer J, Proby C, Sheaf MT, Oliver RT, Baithun S.

J Clin Pathol. 2005 Feb;58(2):207-10.

37.

Hepatocyte growth factor-induced endothelial cell motility is mediated by the upregulation of inducible nitric oxide synthase expression.

Purdie KJ, Whitley GS, Johnstone AP, Cartwright JE.

Cardiovasc Res. 2002 Jun;54(3):659-68.

PMID:
12031712
38.

Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis.

Proby CM, Purdie KJ, Sexton CJ, Purkis P, Navsaria HA, Stables JN, Leigh IM.

Exp Dermatol. 2000 Apr;9(2):104-17.

PMID:
10772384
39.
40.

Cell-type-specific separate regulation of the E6 and E7 promoters of human papillomavirus type 6a by the viral transcription factor E2.

Rapp B, Pawellek A, Kraetzer F, Schaefer M, May C, Purdie K, Grassmann K, Iftner T.

J Virol. 1997 Sep;71(9):6956-66.

41.

A novel human papillomavirus identified in epidermodysplasia verruciformis.

Harris AJ, Purdie K, Leigh IM, Proby C, Burge S.

Br J Dermatol. 1997 Apr;136(4):587-91.

PMID:
9155964
42.

Detection of rDNA sites in sugarcane by FISH.

Jenkin MJ, Reader SM, Purdie KA, Miller TE.

Chromosome Res. 1995 Nov;3(7):444-5.

PMID:
8528591
43.

Managing meningitis.

Purdie K, Paterson A.

Nurs N Z. 1994 Nov;2(10):18-9. No abstract available.

PMID:
7812324
44.

Determination of the frequency of wheat-rye chromosome pairing in wheat x rye hybrids with and without chromosome 5B.

Miller TE, Reader SM, Purdie KA, King IP.

Theor Appl Genet. 1994 Oct;89(2-3):255-8. doi: 10.1007/BF00225150.

PMID:
24177837
45.

Detection of interchromosomal translocations within the Triticeae by RFLP analysis.

King IP, Purdie KA, Liu CJ, Reader SM, Pittaway TS, Orford SE, Miller TE.

Genome. 1994 Oct;37(5):882-7.

PMID:
18470131
46.

Direct labelling of plant chromosomes by rapid in situ hybridization.

Reader SM, Abbo S, Purdie KA, King IP, Miller TE.

Trends Genet. 1994 Aug;10(8):265-6. No abstract available.

PMID:
7940753
47.

Retention of low copy number human papillomavirus DNA in cultured cutaneous and mucosal wart keratinocytes.

Williams AT, Sexton CJ, Sinclair AL, Purdie KJ, Thomas MS, Hanna NA, Goh BT, Williams DM, Leigh IM.

J Gen Virol. 1994 Mar;75 ( Pt 3):505-11.

PMID:
8126448
48.

Malignant transformation of cutaneous lesions in renal allograft patients: a role for human papillomavirus.

Purdie KJ, Sexton CJ, Proby CM, Glover MT, Williams AT, Stables JN, Leigh IM.

Cancer Res. 1993 Nov 1;53(21):5328-33.

49.

Characterization of Thinopyrum bessarabicum chromosome segments in wheat using random amplified polymorphic DNAs (RAPDs) and genomic in situ hybridization.

King IP, Purdie KA, Rezanoor HN, Koebner RM, Miller TE, Reader SM, Nicholson P.

Theor Appl Genet. 1993 Sep;86(8):895-900. doi: 10.1007/BF00211038.

PMID:
24193994
50.

Human interleukin 3: effects on normal and leukemic cells.

Barber KE, Crosier PS, Purdie KJ, Buchanan JM, Cattermole JA, Watson JD, Gillis S.

Growth Factors. 1989;1(2):101-14.

PMID:
2624775

Supplemental Content

Loading ...
Support Center