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Items: 1 to 50 of 95

1.

In vivo monitoring of pancreatic beta-cells in a transgenic mouse model.

Smith SJ, Zhang H, Clermont AO, Powers AC, Kaufman DB, Purchio AF, West DB.

Mol Imaging. 2006 Apr-Jun;5(2):65-75.

PMID:
16954020
2.

Expression of firefly luciferase in Candida albicans and its use in the selection of stable transformants.

Doyle TC, Nawotka KA, Purchio AF, Akin AR, Francis KP, Contag PR.

Microb Pathog. 2006 Feb;40(2):69-81. Epub 2006 Jan 20.

PMID:
16427765
3.

Regulation of IkappaBalpha expression involves both NF-kappaB and the MAP kinase signaling pathways.

Zhang N, Ahsan MH, Zhu L, Sambucetti LC, Purchio AF, West DB.

J Inflamm (Lond). 2005 Oct 5;2:10.

4.

Noninvasive monitoring of pneumococcal meningitis and evaluation of treatment efficacy in an experimental mouse model.

Kadurugamuwa JL, Modi K, Yu J, Francis KP, Orihuela C, Tuomanen E, Purchio AF, Contag PR.

Mol Imaging. 2005 Apr-Jun;4(2):137-42.

PMID:
16105511
5.

Visualizing drug efficacy in vivo.

Weisheng Z, Min C, West DB, Purchio AF.

Mol Imaging. 2005 Apr-Jun;4(2):88-90.

PMID:
16105506
6.

In vivo imaging of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs.

Davies SJ, Smith SJ, Lim KC, Zhang H, Purchio AF, McKerrow JH, West DB.

Int J Parasitol. 2005 Jul;35(8):851-9.

8.

NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation.

Zhang N, Ahsan MH, Zhu L, Sambucetti LC, Purchio AF, West DB.

J Biol Chem. 2005 Jun 3;280(22):21400-8. Epub 2005 Mar 29.

9.

In vivo bioluminescent monitoring of chemical toxicity using heme oxygenase-luciferase transgenic mice.

Malstrom SE, Jekic-McMullen D, Sambucetti L, Ang A, Reeves R, Purchio AF, Contag PR, West DB.

Toxicol Appl Pharmacol. 2004 Nov 1;200(3):219-28.

PMID:
15504458
10.

Non-invasive imaging of GFAP expression after neuronal damage in mice.

Zhu L, Ramboz S, Hewitt D, Boring L, Grass DS, Purchio AF.

Neurosci Lett. 2004 Sep 2;367(2):210-2.

PMID:
15331155
11.

A Cyp1a2-luciferase transgenic CD-1 mouse model: responses to aryl hydrocarbons similar to the humanized AhR mice.

Zhang W, Moorthy B, Chen M, Muthiah K, Coffee R, Purchio AF, West DB.

Toxicol Sci. 2004 Nov;82(1):297-307. Epub 2004 Aug 25.

PMID:
15329440
12.

The characterization and hormonal regulation of kidney androgen-regulated protein (Kap)-luciferase transgenic mice.

Malstrom SE, Tornavaca O, Meseguer A, Purchio AF, West DB.

Toxicol Sci. 2004 Jun;79(2):266-77. Epub 2004 Mar 31.

PMID:
15056803
13.

Differential regulation of the human CYP3A4 promoter in transgenic mice and rats.

Zhang W, Purchio AF, Coffee R, West DB.

Drug Metab Dispos. 2004 Feb;32(2):163-7.

PMID:
14744936
14.

Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse.

Zhang N, Fang Z, Contag PR, Purchio AF, West DB.

Blood. 2004 Jan 15;103(2):617-26. Epub 2003 Sep 25.

PMID:
14512298
15.

A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene.

Zhang W, Purchio AF, Chen K, Wu J, Lu L, Coffee R, Contag PR, West DB.

Drug Metab Dispos. 2003 Aug;31(8):1054-64.

PMID:
12867495
16.

An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice.

Zhang N, Weber A, Li B, Lyons R, Contag PR, Purchio AF, West DB.

J Immunol. 2003 Jun 15;170(12):6307-19.

17.

cDNA cloning of rasp-1, a novel gene encoding a plasma protein associated with liver regeneration.

New L, Liu K, Kamali V, Plowman G, Naughton BA, Purchio AF.

Biochem Biophys Res Commun. 1996 Jun 14;223(2):404-12.

PMID:
8670294
18.

Tgf-Beta promotes the growth of bovine chondrocytes in monolayer culture and the formation of cartilage tissue on three-dimensional scaffolds.

Zimber MP, Tong B, Dunkelman N, Pavelec R, Grande D, New L, Purchio AF.

Tissue Eng. 1995 Fall;1(3):289-300. doi: 10.1089/ten.1995.1.289.

PMID:
19877907
19.

Enhancement of bone ingrowth by transforming growth factor-beta.

Sumner DR, Turner TM, Purchio AF, Gombotz WR, Urban RM, Galante JO.

J Bone Joint Surg Am. 1995 Aug;77(8):1135-47.

PMID:
7642657
20.

Cartilage production by rabbit articular chondrocytes on polyglycolic acid scaffolds in a closed bioreactor system.

Dunkelman NS, Zimber MP, Lebaron RG, Pavelec R, Kwan M, Purchio AF.

Biotechnol Bioeng. 1995 May 20;46(4):299-305.

PMID:
18623316
21.
22.

Nonenzymatic glycosylation of poly-L-lysine: a new tool for targeted gene delivery.

Martinez-Fong D, Mullersman JE, Purchio AF, Armendariz-Borunda J, Martinez-Hernandez A.

Hepatology. 1994 Dec;20(6):1602-8.

PMID:
7982661
23.

The proteoglycan synthesis repertoire of rabbit chondrocytes maintained in type II collagen gels.

Malemud CJ, Stevenson S, Mehraban F, Papay RS, Purchio AF, Goldberg VM.

Osteoarthritis Cartilage. 1994 Mar;2(1):29-41.

PMID:
11548222
24.

Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.

Pierce DF Jr, Johnson MD, Matsui Y, Robinson SD, Gold LI, Purchio AF, Daniel CW, Hogan BL, Moses HL.

Genes Dev. 1993 Dec;7(12A):2308-17.

25.

Metanephric transforming growth factor-beta 1 regulates nephrogenesis in vitro.

Rogers SA, Ryan G, Purchio AF, Hammerman MR.

Am J Physiol. 1993 Jun;264(6 Pt 2):F996-1002.

PMID:
8322902
26.

Transforming growth factor-beta 1 as a signal for induction of cell death by apoptosis.

Bursch W, Oberhammer F, Jirtle RL, Askari M, Sedivy R, Grasl-Kraupp B, Purchio AF, Schulte-Hermann R.

Br J Cancer. 1993 Mar;67(3):531-6.

27.

Linkage localization of TGFB2 and the human homeobox gene HLX1 to chromosome 1q.

Nishimura DY, Purchio AF, Murray JC.

Genomics. 1993 Feb;15(2):357-64.

PMID:
8095486
28.

Transforming growth factor-beta accelerates osteoinduction in a craniofacial onlay model.

Kibblewhite DJ, Bruce AG, Strong DM, Ott SM, Purchio AF, Larrabee WF Jr.

Growth Factors. 1993;9(3):185-93.

PMID:
8274296
29.

Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 (414) precursors and of cysteine residues within mature TGF beta 1: effects on secretion and bioactivity.

Brunner AM, Lioubin MN, Marquardt H, Malacko AR, Wang WC, Shapiro RA, Neubauer M, Cook J, Madisen L, Purchio AF.

Mol Endocrinol. 1992 Oct;6(10):1691-700.

PMID:
1448117
30.

cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta.

Skonier J, Neubauer M, Madisen L, Bennett K, Plowman GD, Purchio AF.

DNA Cell Biol. 1992 Sep;11(7):511-22.

PMID:
1388724
31.

Amplification and expression of heterologous oncostatin M in Chinese hamster ovary cells.

Malik N, Graves D, Shoyab M, Purchio AF.

DNA Cell Biol. 1992 Jul-Aug;11(6):453-9.

PMID:
1524679
32.

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.

Oberhammer FA, Pavelka M, Sharma S, Tiefenbacher R, Purchio AF, Bursch W, Schulte-Hermann R.

Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5408-12.

33.

Characterization of the binding of transforming growth factor-beta 1, -beta 2, and -beta 3 to recombinant beta 1-latency-associated peptide.

Miller DM, Ogawa Y, Iwata KK, ten Dijke P, Purchio AF, Soloff MS, Gentry LE.

Mol Endocrinol. 1992 May;6(5):694-702.

PMID:
1603080
34.

Regulation of amphiregulin mRNA by TGF-beta in the human lung adenocarcinoma cell line A549.

Bennett KL, Plowman GD, Buckley SD, Skonier J, Purchio AF.

Growth Factors. 1992;7(3):207-13.

PMID:
1457126
35.
36.

Identification of a gene family regulated by transforming growth factor-beta.

Brunner A, Chinn J, Neubauer M, Purchio AF.

DNA Cell Biol. 1991 May;10(4):293-300.

PMID:
2029337
37.

Characterization of latent transforming growth factor-beta 2 from monkey kidney cells.

Lioubin MN, Madisen L, Roth RA, Purchio AF.

Endocrinology. 1991 May;128(5):2291-6.

PMID:
1902166
38.

Coordinated regulation of apoptosis and cell proliferation by transforming growth factor beta 1 in cultured uterine epithelial cells.

Rotello RJ, Lieberman RC, Purchio AF, Gerschenson LE.

Proc Natl Acad Sci U S A. 1991 Apr 15;88(8):3412-5.

39.

Expression of recombinant TGF-beta 2(442) precursor and detection in BSC-40 cells.

Madisen L, Lioubin MN, Finerty PJ Jr, Sutter K, Blake J, Frederick J, Purchio AF.

Growth Factors. 1991;5(4):317-25.

PMID:
1777240
40.

Characterization of latent recombinant TGF-beta 2 produced by Chinese hamster ovary cells.

Lioubin MN, Madisen L, Marquardt H, Roth R, Kovacina KS, Purchio AF.

J Cell Biochem. 1991 Jan;45(1):112-21.

PMID:
1848562
41.

Transforming growth factor-beta 1 inhibits ovarian androgen production: gene expression, cellular localization, mechanisms(s), and site(s) of action.

Hernandez ER, Hurwitz A, Payne DW, Dharmarajan AM, Purchio AF, Adashi EY.

Endocrinology. 1990 Dec;127(6):2804-11.

PMID:
2249629
42.
43.

Molecular cloning of a novel bone-forming compound: osteoinductive factor.

Madisen L, Neubauer M, Plowman G, Rosen D, Segarini P, Dasch J, Thompson A, Ziman J, Bentz H, Purchio AF.

DNA Cell Biol. 1990 Jun;9(5):303-9.

PMID:
2372374
44.

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin.

Lyons RM, Gentry LE, Purchio AF, Moses HL.

J Cell Biol. 1990 Apr;110(4):1361-7.

45.
46.

High-level expression of TGF-beta 2 and the TGF-beta 2(414) precursor in Chinese hamster ovary cells.

Madisen L, Lioubin MN, Marquardt H, Purchio AF.

Growth Factors. 1990;3(2):129-38.

PMID:
2206555
47.

Analysis of proteolytic cleavage of recombinant TGF-beta 1: production of hybrid molecules with increased processing efficiency.

Madisen L, Lioubin MN, Farrand AL, Brunner AM, Purchio AF.

Ann N Y Acad Sci. 1990;593:7-25. No abstract available.

PMID:
2197963
48.

Gamma-interferon-induced activation of latent transforming growth factor-beta by human monocytes.

Twardzik DR, Mikovits JA, Ranchalis JE, Purchio AF, Ellingsworth L, Ruscetti FW.

Ann N Y Acad Sci. 1990;593:276-84. No abstract available.

PMID:
2115757
49.
50.

Transforming growth factor beta 1: importance of glycosylation and acidic proteases for processing and secretion.

Sha X, Brunner AM, Purchio AF, Gentry LE.

Mol Endocrinol. 1989 Jul;3(7):1090-8.

PMID:
2677679

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