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Items: 1 to 50 of 599

1.

Select Interviews From the INS Annual Meeting-Keith Humphreys, Tom Insel, Uma Karmarkar, Carl Marci, Ariel Cascio, Winston Chiong, Frederic Gilbert, Cynthia Kubu, and Jonathan Pugh.

Ahlgrim N, Garza K, Hoffman C, Coolidge S, Purcell RH.

AJOB Neurosci. 2019 Jan-Mar;10(1):62-68. doi: 10.1080/21507740.2019.1595773. No abstract available.

PMID:
31070549
2.

Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion.

Rutkowski TP, Purcell RH, Pollak RM, Grewenow SM, Gafford GM, Malone T, Khan UA, Schroeder JP, Epstein MP, Bassell GJ, Warren ST, Weinshenker D, Caspary T, Mulle JG.

Mol Psychiatry. 2019 Apr 11. doi: 10.1038/s41380-019-0413-5. [Epub ahead of print]

3.

Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure.

Chen Z, Diaz G, Pollicino T, Zhao H, Engle RE, Schuck P, Shen CH, Zamboni F, Long Z, Kabat J, De Battista D, Bock KW, Moore IN, Wollenberg K, Soto C, Govindarajan S, Kwong PD, Kleiner DE, Purcell RH, Farci P.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11369-E11378. doi: 10.1073/pnas.1809028115. Epub 2018 Nov 12.

4.

Hepatitis E Virus Seroprevalence and Correlates of Anti-HEV IgG Antibodies in the Rakai District, Uganda.

Boon D, Redd AD, Laeyendecker O, Engle RE, Nguyen H, Ocama P, Boaz I, Ndyanabo A, Kiggundu V, Reynolds SJ, Gray RH, Wawer MJ, Purcell RH, Kirk GD, Quinn TC, Stabinski L; Rakai Health Sciences Program.

J Infect Dis. 2018 Feb 14;217(5):785-789. doi: 10.1093/infdis/jix610.

5.

Adhesion G Protein-Coupled Receptors as Drug Targets.

Purcell RH, Hall RA.

Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:429-449. doi: 10.1146/annurev-pharmtox-010617-052933. Epub 2017 Oct 2. Review.

PMID:
28968187
6.

A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity.

Purcell RH, Toro C, Gahl WA, Hall RA.

Hum Mutat. 2017 Dec;38(12):1751-1760. doi: 10.1002/humu.23336. Epub 2017 Sep 20.

7.

Biometric Tracking From Professional Athletes to Consumers.

Purcell RH, Rommelfanger KS.

Am J Bioeth. 2017 Jan;17(1):72-74. No abstract available.

PMID:
27996927
8.

Reply.

Fontana RJ, Engle RE, Purcell RH, Lee WM; ALFSG.

Hepatology. 2017 Jan;65(1):389-390. doi: 10.1002/hep.28794. Epub 2016 Oct 6. No abstract available.

9.

The role of hepatitis E virus infection in adult Americans with acute liver failure.

Fontana RJ, Engle RE, Scaglione S, Araya V, Shaikh O, Tillman H, Attar N, Purcell RH, Lee WM; US Acute Liver Failure Study Group.

Hepatology. 2016 Dec;64(6):1870-1880. doi: 10.1002/hep.28649. Epub 2016 Jun 23.

10.

Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1).

Kishore A, Purcell RH, Nassiri-Toosi Z, Hall RA.

J Biol Chem. 2016 Feb 12;291(7):3385-94. doi: 10.1074/jbc.M115.689349. Epub 2015 Dec 28.

11.

The Association of Cytokines and Micronutrients with Hepatitis E Virus Infection During Pregnancy and the Postpartum Period in Rural Bangladesh.

Kmush BL, Labrique A, Li W, Klein SL, Schulze K, Shaikh S, Ali H, Engle RE, Wu L, Purcell RH, Mehra S, Christian P, West K Jr, Nelson K.

Am J Trop Med Hyg. 2016 Jan;94(1):203-11. doi: 10.4269/ajtmh.15-0238. Epub 2015 Nov 30.

12.

An Epidemiologic Investigation of a Case of Acute Hepatitis E.

Sarkar S, Rivera EM, Engle RE, Nguyen HT, Schechterly CA, Alter HJ, Liang TJ, Purcell RH, Hoofnagle JH, Ghany MG.

J Clin Microbiol. 2015 Nov;53(11):3547-52. doi: 10.1128/JCM.01189-15. Epub 2015 Sep 2.

13.

Immunoglobulin with High-Titer In Vitro Cross-Neutralizing Hepatitis C Virus Antibodies Passively Protects Chimpanzees from Homologous, but Not Heterologous, Challenge.

Bukh J, Engle RE, Faulk K, Wang RY, Farci P, Alter HJ, Purcell RH.

J Virol. 2015 Sep;89(17):9128-32. doi: 10.1128/JVI.01194-15. Epub 2015 Jun 17.

14.

Bacillus anthracis Capsular Conjugates Elicit Chimpanzee Polyclonal Antibodies That Protect Mice from Pulmonary Anthrax.

Chen Z, Schneerson R, Lovchik JA, Dai Z, Kubler-Kielb J, Agulto L, Leppla SH, Purcell RH.

Clin Vaccine Immunol. 2015 Aug;22(8):902-8. doi: 10.1128/CVI.00137-15. Epub 2015 Jun 3.

15.

Internet-based brain training games, citizen scientists, and big data: ethical issues in unprecedented virtual territories.

Purcell RH, Rommelfanger KS.

Neuron. 2015 Apr 22;86(2):356-9. doi: 10.1016/j.neuron.2015.03.044.

16.

Declining prevalence of hepatitis E antibodies among Danish blood donors.

Holm DK, Moessner BK, Engle RE, Zaaijer HL, Georgsen J, Purcell RH, Christensen PB.

Transfusion. 2015 Jul;55(7):1662-7. doi: 10.1111/trf.13028. Epub 2015 Mar 27.

PMID:
25819381
17.

Complete genome sequence of a rat hepatitis e virus strain isolated in the United States.

Debing Y, Emerson SU, Purcell RH, Neyts J, Dallmeier K.

Genome Announc. 2014 Nov 6;2(6). pii: e01096-14. doi: 10.1128/genomeA.01096-14.

18.

Impact.

Purcell RH.

Natl Med J India. 2013 Nov-Dec;26(6):378-9. No abstract available.

PMID:
25141380
19.

Hepatitis E virus seroprevalence in the United States: no easy answers.

Kuniholm MH, Engle RE, Purcell RH, Nelson KE.

Hepatology. 2015 Apr;61(4):1441-2. doi: 10.1002/hep.27286. Epub 2014 Oct 24. No abstract available.

20.

Hepatitis E virus seroprevalence in the National Health and Nutrition Examination Survey: facts trump opinion.

Engle RE, Kuniholm MH, Nelson KE, Purcell RH.

Hepatology. 2015 Apr;61(4):1442. doi: 10.1002/hep.27292. Epub 2015 Feb 27. No abstract available.

PMID:
24995541
21.

Transfusion-associated hepatitis before the screening of blood for hepatitis risk factors.

Engle RE, Bukh J, Alter HJ, Emerson SU, Trenbeath JL, Nguyen HT, Brockington A, Mitra T, Purcell RH.

Transfusion. 2014 Nov;54(11):2833-41. doi: 10.1111/trf.12682. Epub 2014 May 5.

22.

The BAI subfamily of adhesion GPCRs: synaptic regulation and beyond.

Stephenson JR, Purcell RH, Hall RA.

Trends Pharmacol Sci. 2014 Apr;35(4):208-15. doi: 10.1016/j.tips.2014.02.002. Epub 2014 Mar 15. Review.

23.

Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver.

Wieland SF, Asabe S, Engle RE, Purcell RH, Chisari FV.

J Virol. 2014 May;88(9):5184-8. doi: 10.1128/JVI.03553-13. Epub 2014 Feb 12.

24.

Prenatal stress decreases Bdnf expression and increases methylation of Bdnf exon IV in rats.

Boersma GJ, Lee RS, Cordner ZA, Ewald ER, Purcell RH, Moghadam AA, Tamashiro KL.

Epigenetics. 2014 Mar;9(3):437-47. doi: 10.4161/epi.27558. Epub 2013 Dec 23.

25.

Cross-neutralizing human anti-poliovirus antibodies bind the recognition site for cellular receptor.

Chen Z, Fischer ER, Kouiavskaia D, Hansen BT, Ludtke SJ, Bidzhieva B, Makiya M, Agulto L, Purcell RH, Chumakov K.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20242-7. doi: 10.1073/pnas.1320041110. Epub 2013 Nov 25.

26.

Early postweaning exercise improves central leptin sensitivity in offspring of rat dams fed high-fat diet during pregnancy and lactation.

Sun B, Liang NC, Ewald ER, Purcell RH, Boersma GJ, Yan J, Moran TH, Tamashiro KL.

Am J Physiol Regul Integr Comp Physiol. 2013 Nov 1;305(9):R1076-84. doi: 10.1152/ajpregu.00566.2012. Epub 2013 Sep 11.

27.

Development of Norwalk virus-specific monoclonal antibodies with therapeutic potential for the treatment of Norwalk virus gastroenteritis.

Chen Z, Sosnovtsev SV, Bok K, Parra GI, Makiya M, Agulto L, Green KY, Purcell RH.

J Virol. 2013 Sep;87(17):9547-57. doi: 10.1128/JVI.01376-13. Epub 2013 Jun 19.

28.

Persistent human hepatitis B virus infection in cynomolgus monkeys: a novel animal model in the search for a cure?

Bukh J, Lanford RE, Purcell RH.

Hepatology. 2013 Nov;58(5):1533-6. doi: 10.1002/hep.26560. Epub 2013 Sep 19. No abstract available.

29.

Occult hepatitis B virus infection in chacma baboons, South Africa.

Dickens C, Kew MC, Purcell RH, Kramvis A.

Emerg Infect Dis. 2013 Apr;19(4):598-605. doi: 10.3201/eid1904.121107.

30.

Chronic hepatitis E with neurologic manifestations and rapid progression of liver fibrosis in a liver transplant recipient.

Maddukuri VC, Russo MW, Ahrens WA, Emerson SU, Engle RE, Purcell RH, Thompson EB, Bonkovsky HL.

Dig Dis Sci. 2013 Aug;58(8):2413-6. doi: 10.1007/s10620-013-2628-7. Epub 2013 Mar 20. No abstract available.

PMID:
23512404
31.

Effects of an epilepsy-causing mutation in the SCN1A sodium channel gene on cocaine-induced seizure susceptibility in mice.

Purcell RH, Papale LA, Makinson CD, Sawyer NT, Schroeder JP, Escayg A, Weinshenker D.

Psychopharmacology (Berl). 2013 Jul;228(2):263-70. doi: 10.1007/s00213-013-3034-8. Epub 2013 Mar 14.

32.

Pathobiology of hepatitis E: lessons learned from primate models.

Purcell RH, Engle RE, Govindarajan S, Herbert R, St Claire M, Elkins WR, Cook A, Shaver C, Beauregard M, Swerczek J, Emerson SU.

Emerg Microbes Infect. 2013 Mar;2(3):e9. doi: 10.1038/emi.2013.9. Epub 2013 Mar 13.

33.

Isolation of human monoclonal antibodies to the envelope e2 protein of hepatitis C virus and their characterization.

Shimizu YK, Hijikata M, Oshima M, Shimizu K, Alter HJ, Purcell RH, Yoshikura H, Hotta H.

PLoS One. 2013;8(2):e55874. doi: 10.1371/journal.pone.0055874. Epub 2013 Feb 7.

34.

Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system.

Li YP, Ramirez S, Jensen SB, Purcell RH, Gottwein JM, Bukh J.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19757-62. doi: 10.1073/pnas.1218260109. Epub 2012 Nov 14.

35.

Specificity of an anti-capsid antibody associated with Hepatitis B Virus-related acute liver failure.

Wu W, Chen Z, Cheng N, Watts NR, Stahl SJ, Farci P, Purcell RH, Wingfield PT, Steven AC.

J Struct Biol. 2013 Jan;181(1):53-60. doi: 10.1016/j.jsb.2012.10.004. Epub 2012 Oct 16.

36.

Hepatitis E.

Hoofnagle JH, Nelson KE, Purcell RH.

N Engl J Med. 2012 Sep 27;367(13):1237-44. No abstract available.

PMID:
23013075
37.

Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.

Morin TJ, Broering TJ, Leav BA, Blair BM, Rowley KJ, Boucher EN, Wang Y, Cheslock PS, Knauber M, Olsen DB, Ludmerer SW, Szabo G, Finberg RW, Purcell RH, Lanford RE, Ambrosino DM, Molrine DC, Babcock GJ.

PLoS Pathog. 2012;8(8):e1002895. doi: 10.1371/journal.ppat.1002895. Epub 2012 Aug 30.

38.

Serological evidence for a hepatitis e virus-related agent in goats in the United States.

Sanford BJ, Emerson SU, Purcell RH, Engle RE, Dryman BA, Cecere TE, Buechner-Maxwell V, Sponenberg DP, Meng XJ.

Transbound Emerg Dis. 2013 Dec;60(6):538-45. doi: 10.1111/tbed.12001. Epub 2012 Aug 22.

39.

Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis.

Farci P, Wollenberg K, Diaz G, Engle RE, Lai ME, Klenerman P, Purcell RH, Pybus OG, Alter HJ.

Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14562-7. doi: 10.1073/pnas.1210592109. Epub 2012 Jul 24.

40.

Maternal high-fat diet during gestation or suckling differentially affects offspring leptin sensitivity and obesity.

Sun B, Purcell RH, Terrillion CE, Yan J, Moran TH, Tamashiro KL.

Diabetes. 2012 Nov;61(11):2833-41. doi: 10.2337/db11-0957. Epub 2012 Jun 29.

41.

Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains.

Li YP, Ramirez S, Gottwein JM, Scheel TK, Mikkelsen L, Purcell RH, Bukh J.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):E1101-10. doi: 10.1073/pnas.1203829109. Epub 2012 Mar 30.

42.

Hepatitis E virus in rats, Los Angeles, California, USA.

Purcell RH, Engle RE, Rood MP, Kabrane-Lazizi Y, Nguyen HT, Govindarajan S, St Claire M, Emerson SU.

Emerg Infect Dis. 2011 Dec;17(12):2216-22. doi: 10.3201/eid1712.110482.

43.

Neutralizing antibodies to hepatitis C virus in perinatally infected children followed up prospectively.

Meunier JC, Bukh J, Diaz G, Tovo PA, Casadei AM, Quinti I, Iorio R, Emerson S, Purcell RH, Farci P.

J Infect Dis. 2011 Dec 1;204(11):1741-5. doi: 10.1093/infdis/jir631. Epub 2011 Oct 17.

44.

Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus.

Meunier JC, Gottwein JM, Houghton M, Russell RS, Emerson SU, Bukh J, Purcell RH.

J Infect Dis. 2011 Oct 15;204(8):1186-90. doi: 10.1093/infdis/jir511.

45.

Mouse monoclonal antibodies to anthrax edema factor protect against infection.

Leysath CE, Chen KH, Moayeri M, Crown D, Fattah R, Chen Z, Das SR, Purcell RH, Leppla SH.

Infect Immun. 2011 Nov;79(11):4609-16. doi: 10.1128/IAI.05314-11. Epub 2011 Sep 12.

46.

Transmission of clonal hepatitis C virus genomes reveals the dominant but transitory role of CD8⁺ T cells in early viral evolution.

Callendret B, Bukh J, Eccleston HB, Heksch R, Hasselschwert DL, Purcell RH, Hughes AL, Walker CM.

J Virol. 2011 Nov;85(22):11833-45. doi: 10.1128/JVI.02654-10. Epub 2011 Sep 7.

47.

Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury.

Davern TJ, Chalasani N, Fontana RJ, Hayashi PH, Protiva P, Kleiner DE, Engle RE, Nguyen H, Emerson SU, Purcell RH, Tillmann HL, Gu J, Serrano J, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN).

Gastroenterology. 2011 Nov;141(5):1665-72.e1-9. doi: 10.1053/j.gastro.2011.07.051. Epub 2011 Aug 16.

48.

Comparative evolution of GII.3 and GII.4 norovirus over a 31-year period.

Boon D, Mahar JE, Abente EJ, Kirkwood CD, Purcell RH, Kapikian AZ, Green KY, Bok K.

J Virol. 2011 Sep;85(17):8656-66. doi: 10.1128/JVI.00472-11. Epub 2011 Jun 29.

49.

Maternal stress and high-fat diet effect on maternal behavior, milk composition, and pup ingestive behavior.

Purcell RH, Sun B, Pass LL, Power ML, Moran TH, Tamashiro KL.

Physiol Behav. 2011 Sep 1;104(3):474-9. doi: 10.1016/j.physbeh.2011.05.012. Epub 2011 May 13.

50.

A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice.

Lee RS, Tamashiro KL, Yang X, Purcell RH, Huo Y, Rongione M, Potash JB, Wand GS.

Psychopharmacology (Berl). 2011 Nov;218(1):303-12. doi: 10.1007/s00213-011-2307-3. Epub 2011 Apr 21.

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