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Items: 34

1.

Variability of Length of Small Intestine in Indian Population and Its Correlation with Type 2 Diabetes Mellitus and Obesity.

Purandare A, Phalgune D, Shah S.

Obes Surg. 2019 May 14. doi: 10.1007/s11695-019-03921-5. [Epub ahead of print]

PMID:
31087236
2.

Inhibition of Casein Kinase 2 Disrupts Differentiation of Myeloid Cells in Cancer and Enhances the Efficacy of Immunotherapy in Mice.

Hashimoto A, Gao C, Mastio J, Kossenkov A, Abrams SI, Purandare AV, Desilva H, Wee S, Hunt J, Jure-Kunkel M, Gabrilovich DI.

Cancer Res. 2018 Oct 1;78(19):5644-5655. doi: 10.1158/0008-5472.CAN-18-1229. Epub 2018 Aug 23.

3.

The Partograph in Childbirth: An Absolute Essentiality or a Mere Exercise?

Dalal AR, Purandare AC.

J Obstet Gynaecol India. 2018 Feb;68(1):3-14. doi: 10.1007/s13224-017-1051-y. Epub 2017 Oct 16. Review.

4.

Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms.

Wan H, Schroeder GM, Hart AC, Inghrim J, Grebinski J, Tokarski JS, Lorenzi MV, You D, Mcdevitt T, Penhallow B, Vuppugalla R, Zhang Y, Gu X, Iyer R, Lombardo LJ, Trainor GL, Ruepp S, Lippy J, Blat Y, Sack JS, Khan JA, Stefanski K, Sleczka B, Mathur A, Sun JH, Wong MK, Wu DR, Li P, Gupta A, Arunachalam PN, Pragalathan B, Narayanan S, K C N, Kuppusamy P, Purandare AV.

ACS Med Chem Lett. 2015 Jul 12;6(8):850-5. doi: 10.1021/acsmedchemlett.5b00226. eCollection 2015 Aug 13.

5.

Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors.

Hart AC, Schroeder GM, Wan H, Grebinski J, Inghrim J, Kempson J, Guo J, Pitts WJ, Tokarski JS, Sack JS, Khan JA, Lippy J, Lorenzi MV, You D, McDevitt T, Vuppugalla R, Zhang Y, Lombardo LJ, Trainor GL, Purandare AV.

ACS Med Chem Lett. 2015 Jul 10;6(8):845-9. doi: 10.1021/acsmedchemlett.5b00225. eCollection 2015 Aug 13.

6.

Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.

Lenhart R, Kirov S, Desilva H, Cao J, Lei M, Johnston K, Peterson R, Schweizer L, Purandare A, Ross-Macdonald P, Fairchild C, Wong T, Wee S.

Mol Cancer Ther. 2015 Oct;14(10):2167-74. doi: 10.1158/1535-7163.MCT-15-0037. Epub 2015 Aug 7.

7.

9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors.

Zimmermann K, Sang X, Mastalerz HA, Johnson WL, Zhang G, Liu Q, Batt D, Lombardo LJ, Vyas D, Trainor GL, Tokarski JS, Lorenzi MV, You D, Gottardis MM, Lippy J, Khan J, Sack JS, Purandare AV.

Bioorg Med Chem Lett. 2015 Jul 15;25(14):2809-12. doi: 10.1016/j.bmcl.2015.04.101. Epub 2015 May 11.

PMID:
25987372
8.

A Twist and New Observation in a Case of Persistent Neonatal Hyperuricosuria.

Purandare AV, Broom MA.

Clin Pediatr (Phila). 2015 Aug;54(9):897-9. doi: 10.1177/0009922814551136. Epub 2014 Sep 19. No abstract available.

PMID:
25238778
9.

A cross-sectional study of polycystic ovarian syndrome among adolescent and young girls in Mumbai, India.

Joshi B, Mukherjee S, Patil A, Purandare A, Chauhan S, Vaidya R.

Indian J Endocrinol Metab. 2014 May;18(3):317-24. doi: 10.4103/2230-8210.131162.

10.

Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2.

Purandare AV, McDevitt TM, Wan H, You D, Penhallow B, Han X, Vuppugalla R, Zhang Y, Ruepp SU, Trainor GL, Lombardo L, Pedicord D, Gottardis MM, Ross-Macdonald P, de Silva H, Hosbach J, Emanuel SL, Blat Y, Fitzpatrick E, Taylor TL, McIntyre KW, Michaud E, Mulligan C, Lee FY, Woolfson A, Lasho TL, Pardanani A, Tefferi A, Lorenzi MV.

Leukemia. 2012 Feb;26(2):280-8. doi: 10.1038/leu.2011.292. Epub 2011 Oct 21.

PMID:
22015772
11.

Structural basis for CARM1 inhibition by indole and pyrazole inhibitors.

Sack JS, Thieffine S, Bandiera T, Fasolini M, Duke GJ, Jayaraman L, Kish KF, Klei HE, Purandare AV, Rosettani P, Troiani S, Xie D, Bertrand JA.

Biochem J. 2011 Jun 1;436(2):331-9. doi: 10.1042/BJ20102161.

PMID:
21410432
12.

Pyrrolo[1,2-f]triazines as JAK2 inhibitors: achieving potency and selectivity for JAK2 over JAK3.

Harikrishnan LS, Kamau MG, Wan H, Inghrim JA, Zimmermann K, Sang X, Mastalerz HA, Johnson WL, Zhang G, Lombardo LJ, Poss MA, Trainor GL, Tokarski JS, Lorenzi MV, You D, Gottardis MM, Baldwin KF, Lippy J, Nirschl DS, Qiu R, Miller AV, Khan J, Sack JS, Purandare AV.

Bioorg Med Chem Lett. 2011 Mar 1;21(5):1425-8. doi: 10.1016/j.bmcl.2011.01.022. Epub 2011 Jan 11.

PMID:
21282055
13.

Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies.

Wan H, Huynh T, Pang S, Geng J, Vaccaro W, Poss MA, Trainor GL, Lorenzi MV, Gottardis M, Jayaraman L, Purandare AV.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5063-6. doi: 10.1016/j.bmcl.2009.07.040. Epub 2009 Jul 10.

PMID:
19632837
14.

Ketogenic diet in Indian children with uncontrolled epilepsy.

Nathan JK, Purandare AS, Parekh ZB, Manohar HV.

Indian Pediatr. 2009 Aug;46(8):669-73. Epub 2009 Apr 1.

15.

Kinase drug discovery approaches in chronic myeloproliferative disorders.

Kumar C, Purandare AV, Lee FY, Lorenzi MV.

Oncogene. 2009 Jun 18;28(24):2305-13. doi: 10.1038/onc.2009.107. Epub 2009 May 4. Review.

PMID:
19421140
16.

Optimization of pyrazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1).

Huynh T, Chen Z, Pang S, Geng J, Bandiera T, Bindi S, Vianello P, Roletto F, Thieffine S, Galvani A, Vaccaro W, Poss MA, Trainor GL, Lorenzi MV, Gottardis M, Jayaraman L, Purandare AV.

Bioorg Med Chem Lett. 2009 Jun 1;19(11):2924-7. doi: 10.1016/j.bmcl.2009.04.075. Epub 2009 Apr 22.

PMID:
19419866
17.

Supraphysiological testosterone enanthate administration prevents bone loss and augments bone strength in gonadectomized male and female rats.

Yarrow JF, Conover CF, Purandare AV, Bhakta AM, Zheng N, Conrad B, Altman MK, Franz SE, Wronski TJ, Borst SE.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1213-22. doi: 10.1152/ajpendo.90640.2008. Epub 2008 Sep 9.

18.

Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1).

Purandare AV, Chen Z, Huynh T, Pang S, Geng J, Vaccaro W, Poss MA, Oconnell J, Nowak K, Jayaraman L.

Bioorg Med Chem Lett. 2008 Aug 1;18(15):4438-41. doi: 10.1016/j.bmcl.2008.06.026. Epub 2008 Jun 12.

PMID:
18619839
19.

Preparation of 2,7-diaminosubstituted-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitriles by solid-phase synthesis.

Cavallaro CL, Harikrishnan LS, Chi F, Dodd D, Purandare A.

J Comb Chem. 2008 Jan-Feb;10(1):28-30. Epub 2007 Nov 10. No abstract available.

PMID:
17994705
20.

Core exploration in optimization of chemokine receptor CCR4 antagonists.

Purandare AV, Wan H, Somerville JE, Burke C, Vaccaro W, Yang X, McIntyre KW, Poss MA.

Bioorg Med Chem Lett. 2007 Feb 1;17(3):679-82. Epub 2006 Nov 2.

PMID:
17098428
21.

Antagonists of CCR4 as immunomodulatory agents.

Purandare AV, Somerville JE.

Curr Top Med Chem. 2006;6(13):1335-44. Review.

PMID:
16918452
22.

Optimization of CCR4 antagonists: side-chain exploration.

Purandare AV, Wan H, Gao A, Somerville J, Burke C, Vaccaro W, Yang X, McIntyre KW, Poss MA.

Bioorg Med Chem Lett. 2006 Jan 1;16(1):204-7. Epub 2005 Oct 19.

PMID:
16236499
23.

Identification of chemokine receptor CCR4 antagonist.

Purandare AV, Gao A, Wan H, Somerville J, Burke C, Seachord C, Vaccaro W, Wityak J, Poss MA.

Bioorg Med Chem Lett. 2005 May 16;15(10):2669-72.

PMID:
15863339
24.

Identification of a potent and rapidly reversible inhibitor of the 20S-proteasome.

Purandare AV, Wan H, Laing N, Benbatoul K, Vaccaro W, Poss MA.

Bioorg Med Chem Lett. 2004 Sep 20;14(18):4701-4.

PMID:
15324891
25.

Diaminopyrimidine and diaminopyridine 5-HT7 ligands.

Denhart DJ, Purandare AV, Catt JD, King HD, Gao A, Deskus JA, Poss MA, Stark AD, Torrente JR, Johnson G, Mattson RJ.

Bioorg Med Chem Lett. 2004 Aug 16;14(16):4249-52.

PMID:
15261280
26.

Aminotriazine 5-HT7 antagonists.

Mattson RJ, Denhart DJ, Catt JD, Dee MF, Deskus JA, Ditta JL, Epperson J, Dalton King H, Gao A, Poss MA, Purandare A, Tortolani D, Zhao Y, Yang H, Yeola S, Palmer J, Torrente J, Stark A, Johnson G.

Bioorg Med Chem Lett. 2004 Aug 16;14(16):4245-8.

PMID:
15261279
27.

Effect of hypothyroidism and its treatment on the IGF system in infants and children.

Purandare A, Co Ng L, Godil M, Ahnn SH, Wilson TA.

J Pediatr Endocrinol Metab. 2003 Jan;16(1):35-42. Review.

PMID:
12585338
28.

Spontaneous adrenal hemorrhage associated with transient antiphospholipid antibody in a child.

Purandare A, Godil MA, Prakash D, Parker R, Zerah M, Wilson TA.

Clin Pediatr (Phila). 2001 Jun;40(6):347-50. No abstract available.

PMID:
11824179
29.

Effect of hyperthyroidism on insulin-like growth factor-I (IGF-I) and IGF-binding proteins in adolescent children.

Co Ng LL, Lang CH, Bereket A, Purandare A, Smaldone A, Wilson TA.

J Pediatr Endocrinol Metab. 2000 Sep-Oct;13(8):1073-80.

PMID:
11085184
30.

Congenital nasal pyriform aperture stenosis associated with central diabetes insipidus.

Godil MA, Galvin-Parton P, Monte D, Zerah M, Purandare A, Lane AH, Wilson TA.

J Pediatr. 2000 Aug;137(2):260-2.

PMID:
10931423
31.

HLA frequency, HLA sharing and immunotherapy in the management of recurrent miscarriage.

Purandare AS, Smith DS, Wilson PJ.

Int J Fertil Menopausal Stud. 1993 Jul-Aug;38(4):219-24.

PMID:
8401680
32.

Thymic hyperplasia masquerading as cardiomegaly: MRI validation.

Purandare AA, Vajifdar BU, Kohli A, Vora AM.

Indian Pediatr. 1992 Apr;29(4):496-9. No abstract available.

PMID:
1387113
33.

Phaeochromocytoma of the organ of Zuckerkandl.

Purandare AS, Head CD, Smyllie HC, Aiken D.

J R Coll Surg Edinb. 1980 Nov;25(6):467-9. No abstract available.

PMID:
7230092
34.

Carcinoma of the breast in women under the age of 30.

Purandare AS, Finbow J.

Br Med J. 1978 Sep 9;2(6139):771. No abstract available.

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