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Items: 1 to 50 of 155

1.

Targeting cardiac fibrosis with engineered T cells.

Aghajanian H, Kimura T, Rurik JG, Hancock AS, Leibowitz MS, Li L, Scholler J, Monslow J, Lo A, Han W, Wang T, Bedi K, Morley MP, Linares Saldana RA, Bolar NA, McDaid K, Assenmacher CA, Smith CL, Wirth D, June CH, Margulies KB, Jain R, Puré E, Albelda SM, Epstein JA.

Nature. 2019 Sep;573(7774):430-433. doi: 10.1038/s41586-019-1546-z. Epub 2019 Sep 11.

PMID:
31511695
2.

Influence of hyaluronic acid modification on CD44 binding towards the design of hydrogel biomaterials.

Kwon MY, Wang C, Galarraga JH, Puré E, Han L, Burdick JA.

Biomaterials. 2019 Nov;222:119451. doi: 10.1016/j.biomaterials.2019.119451. Epub 2019 Aug 23.

PMID:
31480001
3.

Fibroblast activation protein restrains adipogenic differentiation and regulates matrix-mediated mTOR signaling.

Blomberg R, Beiting DP, Wabitsch M, Puré E.

Matrix Biol. 2019 Jul 17. pii: S0945-053X(19)30189-1. doi: 10.1016/j.matbio.2019.07.007. [Epub ahead of print]

PMID:
31325484
4.

Deletion of Calcineurin Promotes a Protumorigenic Fibroblast Phenotype.

Lieberman A, Barrett R, Kim J, Zhang KL, Avery D, Monslow J, Kim H, Kim BJ, Puré E, Ryeom S.

Cancer Res. 2019 Aug 1;79(15):3928-3939. doi: 10.1158/0008-5472.CAN-19-0056. Epub 2019 Jun 12.

PMID:
31189649
5.

Loss of cells expressing fibroblast activation protein has variable effects in models of TGF-β and chronic bleomycin-induced fibrosis.

Kimura T, Monslow J, Klampatsa A, Leibowitz M, Sun J, Liousia M, Woodruff P, Moon E, Todd L, Puré E, Albelda SM.

Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L271-L282. doi: 10.1152/ajplung.00071.2019. Epub 2019 Jun 12.

PMID:
31188013
6.

Cardiovascular protection in females linked to estrogen-dependent inhibition of arterial stiffening and macrophage MMP12.

Liu SL, Bajpai A, Hawthorne EA, Bae Y, Castagnino P, Monslow J, Puré E, Spiller KL, Assoian RK.

JCI Insight. 2019 Jan 10;4(1). pii: 122742. doi: 10.1172/jci.insight.122742. [Epub ahead of print]

7.

Seeking Synergy of Checkpoint Blockade through TGFβ Inhibition.

Puré E.

Cancer Immunol Res. 2018 Dec;6(12):1444. doi: 10.1158/2326-6066.CIR-18-0784.

PMID:
30510056
8.

Interleukin 6 Signaling Blockade Exacerbates Acute and Late Injury From Focal Intestinal Irradiation.

Bell BI, Koduri S, Salas Salinas C, Monslow J, Puré E, Ben-Josef E, Koumenis C, Verginadis II.

Int J Radiat Oncol Biol Phys. 2019 Mar 1;103(3):719-727. doi: 10.1016/j.ijrobp.2018.10.007. Epub 2018 Oct 15.

PMID:
30336264
9.

FAP Delineates Heterogeneous and Functionally Divergent Stromal Cells in Immune-Excluded Breast Tumors.

Cremasco V, Astarita JL, Grauel AL, Keerthivasan S, MacIsaac K, Woodruff MC, Wu M, Spel L, Santoro S, Amoozgar Z, Laszewski T, Migoni SC, Knoblich K, Fletcher AL, LaFleur M, Wucherpfennig KW, Pure E, Dranoff G, Carroll MC, Turley SJ.

Cancer Immunol Res. 2018 Dec;6(12):1472-1485. doi: 10.1158/2326-6066.CIR-18-0098. Epub 2018 Sep 28.

PMID:
30266714
10.

CD44-dependent inflammation, fibrogenesis, and collagenolysis regulates extracellular matrix remodeling and tensile strength during cutaneous wound healing.

Govindaraju P, Todd L, Shetye S, Monslow J, Puré E.

Matrix Biol. 2019 Jan;75-76:314-330. doi: 10.1016/j.matbio.2018.06.004. Epub 2018 Jun 9. Review.

PMID:
29894820
11.

The CD44-HA axis and inflammation in atherosclerosis: A temporal perspective.

Krolikoski M, Monslow J, Puré E.

Matrix Biol. 2019 May;78-79:201-218. doi: 10.1016/j.matbio.2018.05.007. Epub 2018 May 21. Review.

PMID:
29792915
12.

Characteristics of the Epithelial-Mesenchymal Transition in Primary and Paired Metastatic Canine Mammary Carcinomas.

Raposo-Ferreira TMM, Brisson BK, Durham AC, Laufer-Amorim R, Kristiansen V, Puré E, Volk SW, Sorenmo K.

Vet Pathol. 2018 Sep;55(5):622-633. doi: 10.1177/0300985818776054. Epub 2018 May 22.

PMID:
29788797
13.

Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics.

Puré E, Blomberg R.

Oncogene. 2018 Aug;37(32):4343-4357. doi: 10.1038/s41388-018-0275-3. Epub 2018 May 3. Review.

14.

Movement and manual therapy for adults with arthritis: 2012 National Health Interview Survey.

Pure E, Terhorst L, Baker N.

Complement Ther Med. 2018 Apr;37:96-102. doi: 10.1016/j.ctim.2018.02.007. Epub 2018 Mar 2.

PMID:
29609944
15.

Mesenchymal Cell Plasticity and Perfidy in Epithelial Malignancy.

Puré E, Hingorani SR.

Trends Cancer. 2018 Apr;4(4):273-277. doi: 10.1016/j.trecan.2018.02.007. Epub 2018 Mar 11. Review.

PMID:
29606311
16.

Extracellular matrix directs phenotypic heterogeneity of activated fibroblasts.

Avery D, Govindaraju P, Jacob M, Todd L, Monslow J, Puré E.

Matrix Biol. 2018 Apr;67:90-106. doi: 10.1016/j.matbio.2017.12.003. Epub 2017 Dec 14.

17.

Stiffness-dependent motility and proliferation uncoupled by deletion of CD44.

Razinia Z, Castagnino P, Xu T, Vázquez-Salgado A, Puré E, Assoian RK.

Sci Rep. 2017 Nov 28;7(1):16499. doi: 10.1038/s41598-017-16486-z.

18.

Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors.

Kumar V, Donthireddy L, Marvel D, Condamine T, Wang F, Lavilla-Alonso S, Hashimoto A, Vonteddu P, Behera R, Goins MA, Mulligan C, Nam B, Hockstein N, Denstman F, Shakamuri S, Speicher DW, Weeraratna AT, Chao T, Vonderheide RH, Languino LR, Ordentlich P, Liu Q, Xu X, Lo A, Puré E, Zhang C, Loboda A, Sepulveda MA, Snyder LA, Gabrilovich DI.

Cancer Cell. 2017 Nov 13;32(5):654-668.e5. doi: 10.1016/j.ccell.2017.10.005.

19.

Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma.

Lo A, Li CP, Buza EL, Blomberg R, Govindaraju P, Avery D, Monslow J, Hsiao M, Puré E.

JCI Insight. 2017 Oct 5;2(19). pii: 92232. doi: 10.1172/jci.insight.92232.

20.

Identification of prognostic collagen signatures and potential therapeutic stromal targets in canine mammary gland carcinoma.

Case A, Brisson BK, Durham AC, Rosen S, Monslow J, Buza E, Salah P, Gillem J, Ruthel G, Veluvolu S, Kristiansen V, Puré E, Brown DC, Sørenmo KU, Volk SW.

PLoS One. 2017 Jul 6;12(7):e0180448. doi: 10.1371/journal.pone.0180448. eCollection 2017.

21.

Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment.

Katlinski KV, Gui J, Katlinskaya YV, Ortiz A, Chakraborty R, Bhattacharya S, Carbone CJ, Beiting DP, Girondo MA, Peck AR, Puré E, Chatterji P, Rustgi AK, Diehl JA, Koumenis C, Rui H, Fuchs SY.

Cancer Cell. 2017 Feb 13;31(2):194-207. doi: 10.1016/j.ccell.2017.01.004.

22.

Cardiovascular Consequences of Prostanoid I Receptor Deletion in Microsomal Prostaglandin E Synthase-1-Deficient Hyperlipidemic Mice.

Tang SY, Monslow J, R Grant G, Todd L, Pawelzik SC, Chen L, Lawson J, Puré E, FitzGerald GA.

Circulation. 2016 Jul 26;134(4):328-38. doi: 10.1161/CIRCULATIONAHA.116.022308.

23.

Augmentation of CAR T-cell Trafficking and Antitumor Efficacy by Blocking Protein Kinase A Localization.

Newick K, O'Brien S, Sun J, Kapoor V, Maceyko S, Lo A, Puré E, Moon E, Albelda SM.

Cancer Immunol Res. 2016 Jun;4(6):541-51. doi: 10.1158/2326-6066.CIR-15-0263. Epub 2016 Apr 4.

24.

Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?

Puré E, Lo A.

Cancer Immunol Res. 2016 Apr;4(4):269-78. doi: 10.1158/2326-6066.CIR-16-0011. Review.

25.

Role for Hyaluronan Synthase 3 in the Response to Vascular Injury.

Puré E, Krolikoski M, Monslow J.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):224-5. doi: 10.1161/ATVBAHA.115.306869. No abstract available.

26.

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice.

Fan MH, Zhu Q, Li HH, Ra HJ, Majumdar S, Gulick DL, Jerome JA, Madsen DH, Christofidou-Solomidou M, Speicher DW, Bachovchin WW, Feghali-Bostwick C, Puré E.

J Biol Chem. 2016 Apr 8;291(15):8070-89. doi: 10.1074/jbc.M115.701433. Epub 2015 Dec 9.

27.

Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening.

Liu SL, Bae YH, Yu C, Monslow J, Hawthorne EA, Castagnino P, Branchetti E, Ferrari G, Damrauer SM, Puré E, Assoian RK.

Sci Rep. 2015 Nov 26;5:17189. doi: 10.1038/srep17189.

28.

Nanoparticles functionalized with collagenase exhibit improved tumor accumulation in a murine xenograft model.

Murty S, Gilliland T, Qiao P, Tabtieng T, Higbee E, Al Zaki A, Puré E, Tsourkas A.

Part Part Syst Charact. 2014 Dec;31(12):1307-1312.

29.

Hyaluronan - a functional and structural sweet spot in the tissue microenvironment.

Monslow J, Govindaraju P, Puré E.

Front Immunol. 2015 May 15;6:231. doi: 10.3389/fimmu.2015.00231. eCollection 2015. Review.

30.

Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.

Lo A, Wang LS, Scholler J, Monslow J, Avery D, Newick K, O'Brien S, Evans RA, Bajor DJ, Clendenin C, Durham AC, Buza EL, Vonderheide RH, June CH, Albelda SM, Puré E.

Cancer Res. 2015 Jul 15;75(14):2800-2810. doi: 10.1158/0008-5472.CAN-14-3041. Epub 2015 May 15.

31.

Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors.

Wang E, Wang LC, Tsai CY, Bhoj V, Gershenson Z, Moon E, Newick K, Sun J, Lo A, Baradet T, Feldman MD, Barrett D, Puré E, Albelda S, Milone MC.

Cancer Immunol Res. 2015 Jul;3(7):815-26. doi: 10.1158/2326-6066.CIR-15-0054. Epub 2015 May 4.

32.

Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer.

Brisson BK, Mauldin EA, Lei W, Vogel LK, Power AM, Lo A, Dopkin D, Khanna C, Wells RG, Puré E, Volk SW.

Am J Pathol. 2015 May;185(5):1471-86. doi: 10.1016/j.ajpath.2015.01.029. Epub 2015 Mar 17.

33.

A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling.

Bae YH, Mui KL, Hsu BY, Liu SL, Cretu A, Razinia Z, Xu T, Puré E, Assoian RK.

Sci Signal. 2014 Jun 17;7(330):ra57. doi: 10.1126/scisignal.2004838.

34.

Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors.

Moon EK, Wang LC, Dolfi DV, Wilson CB, Ranganathan R, Sun J, Kapoor V, Scholler J, Puré E, Milone MC, June CH, Riley JL, Wherry EJ, Albelda SM.

Clin Cancer Res. 2014 Aug 15;20(16):4262-73. doi: 10.1158/1078-0432.CCR-13-2627. Epub 2014 Jun 11.

35.

Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity.

Wang LC, Lo A, Scholler J, Sun J, Majumdar RS, Kapoor V, Antzis M, Cotner CE, Johnson LA, Durham AC, Solomides CC, June CH, Puré E, Albelda SM.

Cancer Immunol Res. 2014 Feb;2(2):154-66. doi: 10.1158/2326-6066.CIR-13-0027. Epub 2013 Nov 12.

36.

Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice.

Chen L, Yang G, Monslow J, Todd L, Cormode DP, Tang J, Grant GR, DeLong JH, Tang SY, Lawson JA, Pure E, Fitzgerald GA.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6828-33. doi: 10.1073/pnas.1401797111. Epub 2014 Apr 21.

37.

Cyclooxygenase-2 in endothelial and vascular smooth muscle cells restrains atherogenesis in hyperlipidemic mice.

Tang SY, Monslow J, Todd L, Lawson J, Puré E, FitzGerald GA.

Circulation. 2014 Apr 29;129(17):1761-9. doi: 10.1161/CIRCULATIONAHA.113.007913. Epub 2014 Feb 11.

38.

Augmentation of integrin-mediated mechanotransduction by hyaluronic acid.

Chopra A, Murray ME, Byfield FJ, Mendez MG, Halleluyan R, Restle DJ, Raz-Ben Aroush D, Galie PA, Pogoda K, Bucki R, Marcinkiewicz C, Prestwich GD, Zarembinski TI, Chen CS, Puré E, Kresh JY, Janmey PA.

Biomaterials. 2014 Jan;35(1):71-82. doi: 10.1016/j.biomaterials.2013.09.066. Epub 2013 Oct 10.

39.

Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.

Tchou J, Zhang PJ, Bi Y, Satija C, Marjumdar R, Stephen TL, Lo A, Chen H, Mies C, June CH, Conejo-Garcia J, Puré E.

Hum Pathol. 2013 Nov;44(11):2549-57. doi: 10.1016/j.humpath.2013.06.016. Epub 2013 Sep 26.

40.

Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53.

Licciulli S, Avila JL, Hanlon L, Troutman S, Cesaroni M, Kota S, Keith B, Simon MC, Puré E, Radtke F, Capobianco AJ, Kissil JL.

Cancer Res. 2013 Oct 1;73(19):5974-84. doi: 10.1158/0008-5472.CAN-13-1384. Epub 2013 Aug 13.

41.

Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis.

Eisinger-Mathason TS, Zhang M, Qiu Q, Skuli N, Nakazawa MS, Karakasheva T, Mucaj V, Shay JE, Stangenberg L, Sadri N, Puré E, Yoon SS, Kirsch DG, Simon MC.

Cancer Discov. 2013 Oct;3(10):1190-205. doi: 10.1158/2159-8290.CD-13-0118. Epub 2013 Aug 1.

42.
43.

Development of drug loaded nanoparticles for tumor targeting. Part 1: Synthesis, characterization, and biological evaluation in 2D cell cultures.

El-Dakdouki MH, Puré E, Huang X.

Nanoscale. 2013 May 7;5(9):3895-903. doi: 10.1039/c3nr33777d. Epub 2013 Mar 26.

44.

Pillars article: T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells. J. Exp. Med. 1982. 155: 734-748.

Isakson PC, Puré E, Vitetta ES, Krammer PH.

J Immunol. 2013 Feb 1;190(3):849-63. No abstract available.

45.

Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening.

Kothapalli D, Liu SL, Bae YH, Monslow J, Xu T, Hawthorne EA, Byfield FJ, Castagnino P, Rao S, Rader DJ, Puré E, Phillips MC, Lund-Katz S, Janmey PA, Assoian RK.

Cell Rep. 2012 Nov 29;2(5):1259-71. doi: 10.1016/j.celrep.2012.09.018. Epub 2012 Oct 25.

46.

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.

Tchou J, Kossenkov AV, Chang L, Satija C, Herlyn M, Showe LC, Puré E.

BMC Med Genomics. 2012 Sep 6;5:39. doi: 10.1186/1755-8794-5-39.

47.

Fibroblast activation protein in remodeling tissues.

Jacob M, Chang L, Puré E.

Curr Mol Med. 2012 Dec;12(10):1220-43. Review.

PMID:
22834826
48.

Vascular COX-2 modulates blood pressure and thrombosis in mice.

Yu Y, Ricciotti E, Scalia R, Tang SY, Grant G, Yu Z, Landesberg G, Crichton I, Wu W, Puré E, Funk CD, FitzGerald GA.

Sci Transl Med. 2012 May 2;4(132):132ra54. doi: 10.1126/scitranslmed.3003787.

49.

Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.

Yu Z, Crichton I, Tang SY, Hui Y, Ricciotti E, Levin MD, Lawson JA, Puré E, FitzGerald GA.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6727-32. doi: 10.1073/pnas.1115313109. Epub 2012 Apr 9.

50.

Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.

Song WL, Stubbe J, Ricciotti E, Alamuddin N, Ibrahim S, Crichton I, Prempeh M, Lawson JA, Wilensky RL, Rasmussen LM, Puré E, FitzGerald GA.

J Clin Invest. 2012 Apr;122(4):1459-68. doi: 10.1172/JCI59262. Epub 2012 Mar 12.

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