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Items: 1 to 50 of 61

1.

Antifungal compounds from Streptomyces associated with attine ants also inhibit Leishmania donovani.

Ortega HE, Ferreira LLG, Melo WGP, Oliveira ALL, Ramos Alvarenga RF, Lopes NP, Bugni TS, Andricopulo AD, Pupo MT.

PLoS Negl Trop Dis. 2019 Aug 5;13(8):e0007643. doi: 10.1371/journal.pntd.0007643. eCollection 2019 Aug.

2.

Microbial community modulates growth of symbiotic fungus required for stingless bee metamorphosis.

Paludo CR, Pishchany G, Andrade-Dominguez A, Silva-Junior EA, Menezes C, Nascimento FS, Currie CR, Kolter R, Clardy J, Pupo MT.

PLoS One. 2019 Jul 25;14(7):e0219696. doi: 10.1371/journal.pone.0219696. eCollection 2019.

3.

The antimicrobial potential of Streptomyces from insect microbiomes.

Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo WGP, Pinto-Tomás AA, Schmitz A, Wendt-Pienkowski E, Wildman S, Zhao M, Zhang F, Bugni TS, Andes DR, Pupo MT, Currie CR.

Nat Commun. 2019 Jan 31;10(1):516. doi: 10.1038/s41467-019-08438-0.

4.

Symbiotic skin bacteria as a source for sex-specific scents in frogs.

Brunetti AE, Lyra ML, Melo WGP, Andrade LE, Palacios-Rodríguez P, Prado BM, Haddad CFB, Pupo MT, Lopes NP.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2124-2129. doi: 10.1073/pnas.1806834116. Epub 2019 Jan 22.

5.

Paenibacillus polymyxa Associated with the Stingless Bee Melipona scutellaris Produces Antimicrobial Compounds against Entomopathogens.

Menegatti C, Da Paixão Melo WG, Carrão DB, De Oliveira ARM, Do Nascimento FS, Lopes NP, Pupo MT.

J Chem Ecol. 2018 Dec;44(12):1158-1169. doi: 10.1007/s10886-018-1028-z. Epub 2018 Oct 23.

PMID:
30350228
6.

Convergent evolution of complex structures for ant-bacterial defensive symbiosis in fungus-farming ants.

Li H, Sosa-Calvo J, Horn HA, Pupo MT, Clardy J, Rabeling C, Schultz TR, Currie CR.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10720-10725. doi: 10.1073/pnas.1809332115. Epub 2018 Oct 3.

7.

Chemical interaction of endophytic fungi and actinobacteria from Lychnophora ericoides in co-cultures.

Chagas FO, Pupo MT.

Microbiol Res. 2018 Jul - Aug;212-213:10-16. doi: 10.1016/j.micres.2018.04.005. Epub 2018 Apr 24.

8.

Absolute Configurations of Griseorhodins A and C.

Ortega HE, Batista JM Jr, Melo WGP, Clardy J, Pupo MT.

Tetrahedron Lett. 2017 Dec 13;58(50):4721-4723. doi: 10.1016/j.tetlet.2017.11.008. Epub 2017 Nov 7.

9.

Pyrazines from bacteria and ants: convergent chemistry within an ecological niche.

Silva-Junior EA, Ruzzini AC, Paludo CR, Nascimento FS, Currie CR, Clardy J, Pupo MT.

Sci Rep. 2018 Feb 7;8(1):2595. doi: 10.1038/s41598-018-20953-6.

10.

Stingless Bee Larvae Require Fungal Steroid to Pupate.

Paludo CR, Menezes C, Silva-Junior EA, Vollet-Neto A, Andrade-Dominguez A, Pishchany G, Khadempour L, do Nascimento FS, Currie CR, Kolter R, Clardy J, Pupo MT.

Sci Rep. 2018 Jan 18;8(1):1122. doi: 10.1038/s41598-018-19583-9.

11.

The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3',4'-methylenedioxyphenyl]-coumarin downmodulates the FcγR- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation and release of neutrophil extracellular traps.

Andrade MF, Kabeya LM, Bortot LO, Dos Santos GB, Santos EOL, Albiero LR, Figueiredo-Rinhel ASG, Carvalho CA, Azzolini AECS, Caliri A, Pupo MT, Emery FS, Lucisano-Valim YM.

Free Radic Biol Med. 2018 Feb 1;115:421-435. doi: 10.1016/j.freeradbiomed.2017.12.012. Epub 2017 Dec 14.

PMID:
29248721
12.

Chemical signaling involved in plant-microbe interactions.

Chagas FO, Pessotti RC, Caraballo-Rodríguez AM, Pupo MT.

Chem Soc Rev. 2018 Mar 5;47(5):1652-1704. doi: 10.1039/c7cs00343a. Review.

PMID:
29218336
13.

Molecular inter-kingdom interactions of endophytes isolated from Lychnophora ericoides.

Caraballo-Rodríguez AM, Dorrestein PC, Pupo MT.

Sci Rep. 2017 Jul 14;7(1):5373. doi: 10.1038/s41598-017-05532-5.

14.

Gas-phase fragmentation of protonated piplartine and its fungal metabolites using tandem mass spectrometry and computational chemistry.

da Silva-Junior EA, Paludo CR, Gouvea DR, Kato MJ, Furtado NAJC, Lopes NP, Vessecchi R, Pupo MT.

J Mass Spectrom. 2017 Aug;52(8):517-525. doi: 10.1002/jms.3955.

PMID:
28581151
15.

Expanding the Chemical Repertoire of the Endophyte Streptomyces albospinus RLe7 Reveals Amphotericin B as an Inducer of a Fungal Phenotype.

Chagas FO, Caraballo-Rodríguez AM, Dorrestein PC, Pupo MT.

J Nat Prod. 2017 May 26;80(5):1302-1309. doi: 10.1021/acs.jnatprod.6b00870. Epub 2017 Apr 4.

PMID:
28375005
16.

Genome Sequence of Streptomyces sp. Strain RTd22, an Endophyte of the Mexican Sunflower.

Chagas FO, Ruzzini AC, Bacha LV, Samborskyy M, Conti R, Pessotti RC, de Oliveira LG, Clardy J, Pupo MT.

Genome Announc. 2016 Jul 21;4(4). pii: e00693-16. doi: 10.1128/genomeA.00693-16.

17.

Endophytic Actinobacteria from the Brazilian Medicinal Plant Lychnophora ericoides Mart. and the Biological Potential of Their Secondary Metabolites.

Conti R, Chagas FO, Caraballo-Rodriguez AM, Melo WG, do Nascimento AM, Cavalcanti BC, de Moraes MO, Pessoa C, Costa-Lotufo LV, Krogh R, Andricopulo AD, Lopes NP, Pupo MT.

Chem Biodivers. 2016 Jun;13(6):727-36. doi: 10.1002/cbdv.201500225. Epub 2016 May 20.

PMID:
27128202
18.

Whole-Genome Sequence of Bacillus sp. SDLI1, Isolated from the Social Bee Scaptotrigona depilis.

Paludo CR, Ruzzini AC, Silva-Junior EA, Pishchany G, Currie CR, Nascimento FS, Kolter RG, Clardy J, Pupo MT.

Genome Announc. 2016 Mar 24;4(2). pii: e00174-16. doi: 10.1128/genomeA.00174-16.

19.

Semisynthesis of new aphidicolin derivatives with high activity against Trypanosoma cruzi.

Santos GB, Krogh R, Magalhaes LG, Andricopulo AD, Pupo MT, Emery FS.

Bioorg Med Chem Lett. 2016 Feb 15;26(4):1205-8. doi: 10.1016/j.bmcl.2016.01.033. Epub 2016 Jan 14.

PMID:
26810263
20.

Global biogeographic sampling of bacterial secondary metabolism.

Charlop-Powers Z, Owen JG, Reddy BV, Ternei MA, Guimarães DO, de Frias UA, Pupo MT, Seepe P, Feng Z, Brady SF.

Elife. 2015 Jan 19;4:e05048. doi: 10.7554/eLife.05048.

21.

A new enantioselective CE method for determination of oxcarbazepine and licarbazepine after fungal biotransformation.

Bocato MZ, Bortoleto MA, Pupo MT, de Oliveira AR.

Electrophoresis. 2014 Oct;35(19):2877-84. doi: 10.1002/elps.201400137. Epub 2014 Aug 18.

PMID:
24981999
22.

The anti-promyelocytic leukemia mode of action of two endophytic secondary metabolites unveiled by a proteomic approach.

Gallo MB, Falso MJ, Balem F, Menezes D, Rocha N, Balachandran R, Sturgeon TS, Pupo MT, Day BW.

Planta Med. 2014 Apr;80(6):473-81. doi: 10.1055/s-0034-1368301. Epub 2014 Apr 7.

PMID:
24710897
23.

In vitro metabolism of the alkaloid piplartine by rat liver microsomes.

Marques LM, da Silva EA Jr, Gouvea DR, Vessecchi R, Pupo MT, Lopes NP, Kato MJ, de Oliveira AR.

J Pharm Biomed Anal. 2014 Jul;95:113-20. doi: 10.1016/j.jpba.2014.02.020. Epub 2014 Mar 6.

PMID:
24667565
24.

Mycoleptones A-C and polyketides from the endophyte Mycoleptodiscus indicus.

Andrioli WJ, Conti R, Araújo MJ, Zanasi R, Cavalcanti BC, Manfrim V, Toledo JS, Tedesco D, de Moraes MO, Pessoa C, Cruz AK, Bertucci C, Sabino J, Nanayakkara DN, Pupo MT, Bastos JK.

J Nat Prod. 2014 Jan 24;77(1):70-8. doi: 10.1021/np4006822. Epub 2014 Jan 3.

PMID:
24387625
25.

Evaluation of dispersive liquid-liquid microextraction in the stereoselective determination of cetirizine following the fungal biotransformation of hydroxyzine and analysis by capillary electrophoresis.

Fortes SS, Barth T, Furtado NA, Pupo MT, de Gaitani CM, de Oliveira AR.

Talanta. 2013 Nov 15;116:743-52. doi: 10.1016/j.talanta.2013.07.062. Epub 2013 Aug 1.

26.

Unusual biotransformation products of the sesquiterpene lactone budlein A by Aspergillus species.

Arakawa NS, Gobbo-Neto L, Ambrosio SR, Antonucci GA, Sampaio SV, Pupo MT, Said S, Schmidt TJ, Da Costa FB.

Phytochemistry. 2013 Dec;96:92-100. doi: 10.1016/j.phytochem.2013.09.022. Epub 2013 Oct 14.

PMID:
24135634
27.

A mixed culture of endophytic fungi increases production of antifungal polyketides.

Chagas FO, Dias LG, Pupo MT.

J Chem Ecol. 2013 Oct;39(10):1335-42. doi: 10.1007/s10886-013-0351-7. Epub 2013 Oct 11.

PMID:
24114180
28.

A biosynthetic pathway of sesquiterpene lactones in Smallanthus sonchifolius and their localization in leaf tissues by MALDI imaging.

Lopes AA, Pina ES, Silva DB, Pereira AM, da Silva MF, Da Costa FB, Lopes NP, Pupo MT.

Chem Commun (Camb). 2013 Nov 4;49(85):9989-91. doi: 10.1039/c3cc46213g.

PMID:
24042494
29.

3-Phenylcoumarin derivatives selectively modulate different steps of reactive oxygen species production by immune complex-stimulated human neutrophils.

Andrade MF, Kabeya LM, Azzolini AE, Santos EO, Figueiredo-Rinhel AS, Paris MR, Emery FS, Pupo MT, Lucisano-Valim YM.

Int Immunopharmacol. 2013 Feb;15(2):387-94. doi: 10.1016/j.intimp.2013.01.001. Epub 2013 Jan 16.

30.

HPLC analysis of midodrine and desglymidodrine in culture medium: evaluation of static and shaken conditions on the biotransformation by fungi.

Barth T, Aleu J, Pupo MT, Bonato PS, Collado IG.

J Chromatogr Sci. 2013 May-Jun;51(5):460-7. doi: 10.1093/chromsci/bms163. Epub 2012 Oct 9.

PMID:
23051063
31.

In vitro metabolism study of the promising anticancer agent the lignan (-)-grandisin.

Messiano GB, Santos RA, Ferreira Lde S, Simões RA, Jabor VA, Kato MJ, Lopes NP, Pupo MT, de Oliveira AR.

J Pharm Biomed Anal. 2013 Jan;72:240-4. doi: 10.1016/j.jpba.2012.08.028. Epub 2012 Aug 31.

PMID:
22995290
32.

Solid phase microextraction and LC-MS/MS for the determination of paliperidone after stereoselective fungal biotransformation of risperidone.

Bocato MZ, Simões RA, Calixto LA, de Gaitani CM, Pupo MT, de Oliveira AR.

Anal Chim Acta. 2012 Sep 12;742:80-9. doi: 10.1016/j.aca.2012.05.056. Epub 2012 Jun 9.

PMID:
22884211
33.

Microbial transformation of the sesquiterpene lactone tagitinin C by the fungus Aspergillus terreus.

Rocha BA, Pupo MT, Antonucci GA, Sampaio SV, de Melo Alves Paiva R, Said S, Gobbo-Neto L, Da Costa FB.

J Ind Microbiol Biotechnol. 2012 Nov;39(11):1719-24. doi: 10.1007/s10295-012-1165-2. Epub 2012 Jul 11.

PMID:
22782617
34.

Chiral HPLC analysis of donepezil, 5-O-desmethyl donepezil and 6-O-desmethyl donepezil in culture medium: application to fungal biotransformation studies.

Barth T, Conti R, Pupo MT, Okano LT, Bonato PS.

Anal Bioanal Chem. 2012 Jul;404(1):257-66. doi: 10.1007/s00216-012-6107-3. Epub 2012 May 29.

PMID:
22644152
35.

Δ-lactam derivative from thermophilic soil fungus exhibits in vitro anti-allergic activity.

Andrioli WJ, Santos MS, Silva VB, Oliveira RB, Chagas-Paula DA, Jorge JA, Furtado NA, Pupo MT, Silva CH, Naal RM, Bastos JK.

Nat Prod Res. 2012;26(23):2168-75. doi: 10.1080/14786419.2011.647020. Epub 2012 Jan 12.

PMID:
22239222
36.

Assessment of the stereoselective fungal biotransformation of albendazole and its analysis by HPLC in polar organic mode.

Hilário VC, Carrão DB, Barth T, Borges KB, Furtado NA, Pupo MT, de Oliveira AR.

J Pharm Biomed Anal. 2012 Mar 5;61:100-7. doi: 10.1016/j.jpba.2011.12.012. Epub 2011 Dec 21.

PMID:
22230802
37.

Stereoselective liquid chromatographic determination of 1'-oxobufuralol and 1'-hydroxybufuralol in rat liver microsomal fraction using hollow-fiber liquid-phase microextraction for sample preparation.

Barth T, Simões RA, Pupo MT, Okano LT, Bonato PS.

J Sep Sci. 2011 Dec;34(24):3578-86. doi: 10.1002/jssc.201100464. Epub 2011 Sep 16.

PMID:
21928435
38.

Capillary electrophoresis and hollow fiber liquid-phase microextraction for the enantioselective determination of albendazole sulfoxide after biotransformation of albendazole by an endophytic fungus.

Carrão DB, Borges KB, Barth T, Pupo MT, Bonato PS, de Oliveira AR.

Electrophoresis. 2011 Oct;32(19):2746-56. doi: 10.1002/elps.201000658. Epub 2011 Sep 8.

PMID:
21905046
39.

Enantioselective fungal biotransformation of risperidone in liquid culture medium by capillary electrophoresis and hollow fiber liquid-phase microextraction.

de Jesus LI, Albuquerque NC, Borges KB, Simões RA, Calixto LA, Furtado NA, de Gaitani CM, Pupo MT, de Oliveira AR.

Electrophoresis. 2011 Oct;32(19):2765-75. doi: 10.1002/elps.201100328. Epub 2011 Sep 5.

PMID:
21898463
40.

Azaphilones from the endophyte Chaetomium globosum.

Borges WS, Mancilla G, Guimarães DO, Durán-Patrón R, Collado IG, Pupo MT.

J Nat Prod. 2011 May 27;74(5):1182-7. doi: 10.1021/np200110f. Epub 2011 May 6. Erratum in: J Nat Prod. 2011 Sep 23;74(9):2028.

PMID:
21548578
42.

Chemical constituents of Papulaspora immersa, an endophyte from Smallanthus sonchifolius (Asteraceae), and their cytotoxic activity.

Gallo MB, Cavalcanti BC, Barros FW, Odorico de Moraes M, Costa-Lotufo LV, Pessoa C, Bastos JK, Pupo MT.

Chem Biodivers. 2010 Dec;7(12):2941-50. doi: 10.1002/cbdv.201000011.

PMID:
21162007
43.

LC-MS-MS determination of ibuprofen, 2-hydroxyibuprofen enantiomers, and carboxyibuprofen stereoisomers for application in biotransformation studies employing endophytic fungi.

Borges KB, de Oliveira AR, Barth T, Jabor VA, Pupo MT, Bonato PS.

Anal Bioanal Chem. 2011 Jan;399(2):915-25. doi: 10.1007/s00216-010-4329-9. Epub 2010 Nov 16.

PMID:
21079932
44.

Diketopiperazines produced by endophytic fungi found in association with two Asteraceae species.

Guimarães DO, Borges WS, Vieira NJ, de Oliveira LF, da Silva CH, Lopes NP, Dias LG, Durán-Patrón R, Collado IG, Pupo MT.

Phytochemistry. 2010 Aug;71(11-12):1423-9. doi: 10.1016/j.phytochem.2010.05.012. Epub 2010 Jun 10.

PMID:
20541231
45.

Stereoselective determination of midodrine and desglymidodrine in culture medium: application to a biotransformation study employing endophytic fungi.

Barth T, Pupo MT, Borges KB, Okano LT, Bonato PS.

Electrophoresis. 2010 May;31(9):1521-8. doi: 10.1002/elps.200900685.

PMID:
20376815
46.

Enantioselective analysis of propranolol and 4-hydroxypropranolol by CE with application to biotransformation studies employing endophytic fungi.

Borges KB, Pupo MT, Bonato PS.

Electrophoresis. 2009 Nov;30(22):3910-7. doi: 10.1002/elps.200900216.

PMID:
19876961
47.

Box-Behnken design for the optimization of an enantioselective method for the simultaneous analysis of propranolol and 4-hydroxypropranolol by CE.

Borges KB, Pupo MT, de Freitas LA, Bonato PS.

Electrophoresis. 2009 Aug;30(16):2874-81. doi: 10.1002/elps.200800821.

PMID:
19691051
48.

A stabilized demethoxyviridin derivative inhibits PI3 kinase.

Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4223-7. doi: 10.1016/j.bmcl.2009.05.105. Epub 2009 May 30.

49.

Endophytic fungi found in association with Smallanthus sonchifolius (Asteraceae) as resourceful producers of cytotoxic bioactive natural products.

Gallo MB, Chagas FO, Almeida MO, Macedo CC, Cavalcanti BC, Barros FW, de Moraes MO, Costa-Lotufo LV, Pessoa C, Bastos JK, Pupo MT.

J Basic Microbiol. 2009 Apr;49(2):142-51. doi: 10.1002/jobm.200800093.

PMID:
18798172
50.

Biological activities from extracts of endophytic fungi isolated from Viguiera arenaria and Tithonia diversifolia.

Guimarães DO, Borges WS, Kawano CY, Ribeiro PH, Goldman GH, Nomizo A, Thiemann OH, Oliva G, Lopes NP, Pupo MT.

FEMS Immunol Med Microbiol. 2008 Jan;52(1):134-44. Epub 2007 Dec 11.

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