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Items: 21

1.

Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.

Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, Dairiki R, Kawakita Y, Mizojiri R, Ito Y, Asano M, Maezaki H, Nakayama Y, Kaishima M, Hayashi K, Teratani M, Miyakawa S, Iwatani M, Miyamoto M, Klein MG, Lane W, Snell G, Tjhen R, He X, Pulukuri S, Nomura T.

EMBO Mol Med. 2018 Jun;10(6). pii: e8289. doi: 10.15252/emmm.201708289.

2.

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.

Hyer ML, Milhollen MA, Ciavarri J, Fleming P, Traore T, Sappal D, Huck J, Shi J, Gavin J, Brownell J, Yang Y, Stringer B, Griffin R, Bruzzese F, Soucy T, Duffy J, Rabino C, Riceberg J, Hoar K, Lublinsky A, Menon S, Sintchak M, Bump N, Pulukuri SM, Langston S, Tirrell S, Kuranda M, Veiby P, Newcomb J, Li P, Wu JT, Powe J, Dick LR, Greenspan P, Galvin K, Manfredi M, Claiborne C, Amidon BS, Bence NF.

Nat Med. 2018 Feb;24(2):186-193. doi: 10.1038/nm.4474. Epub 2018 Jan 15.

PMID:
29334375
3.

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor.

He X, Riceberg J, Soucy T, Koenig E, Minissale J, Gallery M, Bernard H, Yang X, Liao H, Rabino C, Shah P, Xega K, Yan ZH, Sintchak M, Bradley J, Xu H, Duffey M, England D, Mizutani H, Hu Z, Guo J, Chau R, Dick LR, Brownell JE, Newcomb J, Langston S, Lightcap ES, Bence N, Pulukuri SM.

Nat Chem Biol. 2017 Nov;13(11):1164-1171. doi: 10.1038/nchembio.2463. Epub 2017 Sep 11.

PMID:
28892090
4.

Characterization of the loss of SUMO pathway function on cancer cells and tumor proliferation.

He X, Riceberg J, Pulukuri SM, Grossman S, Shinde V, Shah P, Brownell JE, Dick L, Newcomb J, Bence N.

PLoS One. 2015 Apr 10;10(4):e0123882. doi: 10.1371/journal.pone.0123882. eCollection 2015.

5.

Pharmacological characterization of chemically synthesized monomeric phi29 pRNA nanoparticles for systemic delivery.

Abdelmawla S, Guo S, Zhang L, Pulukuri SM, Patankar P, Conley P, Trebley J, Guo P, Li QX.

Mol Ther. 2011 Jul;19(7):1312-22. doi: 10.1038/mt.2011.35. Epub 2011 Apr 5. Erratum in: Mol Ther. 2011 Sep;19(9):1748.

6.

Epigenetic upregulation of urokinase plasminogen activator promotes the tropism of mesenchymal stem cells for tumor cells.

Pulukuri SM, Gorantla B, Dasari VR, Gondi CS, Rao JS.

Mol Cancer Res. 2010 Aug;8(8):1074-83. doi: 10.1158/1541-7786.MCR-09-0495. Epub 2010 Jul 27.

7.

Small interfering RNA-directed knockdown of uracil DNA glycosylase induces apoptosis and sensitizes human prostate cancer cells to genotoxic stress.

Pulukuri SM, Knost JA, Estes N, Rao JS.

Mol Cancer Res. 2009 Aug;7(8):1285-93. doi: 10.1158/1541-7786.MCR-08-0508. Epub 2009 Aug 11.

8.

Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer.

Pulukuri SM, Gorantla B, Knost JA, Rao JS.

Oncogene. 2009 Aug 6;28(31):2829-38. doi: 10.1038/onc.2009.134. Epub 2009 Jun 8.

9.

uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo.

Kargiotis O, Chetty C, Gogineni V, Gondi CS, Pulukuri SM, Kyritsis AP, Gujrati M, Klopfenstein JD, Dinh DH, Rao JS.

Int J Oncol. 2008 Nov;33(5):937-47.

10.

Matrix metalloproteinase-1 promotes prostate tumor growth and metastasis.

Pulukuri SM, Rao JS.

Int J Oncol. 2008 Apr;32(4):757-65.

11.
13.

Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors.

Pulukuri SM, Patibandla S, Patel J, Estes N, Rao JS.

Oncogene. 2007 Aug 9;26(36):5229-37. Epub 2007 Feb 26.

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Retinaldehyde, a potent inhibitor of gap junctional intercellular communication.

Pulukuri S, Sitaramayya A.

Cell Commun Adhes. 2004 Jan-Feb;11(1):25-33.

PMID:
15500295
19.

Connexin 36 in photoreceptor cells: studies on transgenic rod-less and cone-less mouse retinas.

Dang L, Pulukuri S, Mears AJ, Swaroop A, Reese BE, Sitaramayya A.

Mol Vis. 2004 May 11;10:323-7.

20.

Connexin 36 in bovine retina: lack of phosphorylation but evidence for association with phosphorylated proteins.

Sitaramayya A, Crabb JW, Matesic DF, Margulis A, Singh V, Pulukuri S, Dang L.

Vis Neurosci. 2003 Jul-Aug;20(4):385-95.

PMID:
14658767
21.

Presence of phosducin in the nuclei of bovine retinal cells.

Margulis A, Dang L, Pulukuri S, Lee R, Sitaramayya A.

Mol Vis. 2002 Dec 19;8:477-82.

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