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Items: 1 to 50 of 206

1.

Educational Recommendations on Selected Analytical and Clinical Aspects of Natriuretic Peptides with a Focus on Heart Failure: A Report from the IFCC Committee on Clinical Applications of Cardiac Bio-Markers.

Kavsak PA, Lam CSP, Saenger AK, Jaffe AS, Collinson P, Pulkki K, Omland T, Lefèvre G, Body R, Ordonez-Llanos J, Apple FS.

Clin Chem. 2019 Oct;65(10):1221-1227. doi: 10.1373/clinchem.2019.306621. Epub 2019 Aug 6.

PMID:
31387884
2.

Levels of Growth Differentiation Factor 15 and Early Mortality Risk Stratification in Cardiogenic Shock.

Hongisto M, Kataja A, Tarvasmäki T, Holopainen A, Javanainen T, Jurkko R, Jäntti T, Kimmoun A, Levy B, Mebazaa A, Pulkki K, Sionis A, Tolppanen H, Wollert KC, Harjola VP, Lassus J; CardShock investigators.

J Card Fail. 2019 Jul 13. pii: S1071-9164(19)30207-6. doi: 10.1016/j.cardfail.2019.07.003. [Epub ahead of print]

PMID:
31310811
3.

Serum Neurofilament Light Chain Concentration Correlates with Infarct Volume but Not Prognosis in Acute Ischemic Stroke.

Onatsu J, Vanninen R, Jäkälä P, Mustonen P, Pulkki K, Korhonen M, Hedman M, Zetterberg H, Blennow K, Höglund K, Herukka SK, Taina M.

J Stroke Cerebrovasc Dis. 2019 Aug;28(8):2242-2249. doi: 10.1016/j.jstrokecerebrovasdis.2019.05.008. Epub 2019 May 28.

PMID:
31151840
4.

MMP-10 and TIMP-1 as indicators of severe sepsis in adult hematological patients with febrile neutropenia.

Becker S, Korpelainen S, Arvonen M, Hämäläinen S, Jantunen E, Lappalainen M, Pulkki K, Riikonen P, Juutilainen A.

Leuk Lymphoma. 2019 May 24:1-8. doi: 10.1080/10428194.2019.1617859. [Epub ahead of print]

PMID:
31122146
5.

Hypoalbuminemia is a frequent marker of increased mortality in cardiogenic shock.

Jäntti T, Tarvasmäki T, Harjola VP, Parissis J, Pulkki K, Javanainen T, Tolppanen H, Jurkko R, Hongisto M, Kataja A, Sionis A, Silva-Cardoso J, Banaszewski M, Spinar J, Mebazaa A, Lassus J; CardShock investigators.

PLoS One. 2019 May 16;14(5):e0217006. doi: 10.1371/journal.pone.0217006. eCollection 2019.

6.

Circulating levels of microRNA 423-5p are associated with 90 day mortality in cardiogenic shock.

Jäntti T, Segersvärd H, Tolppanen H, Tarvasmäki T, Lassus J, Devaux Y, Vausort M, Pulkki K, Sionis A, Bayes-Genis A, Tikkanen I, Lakkisto P, Harjola VP.

ESC Heart Fail. 2019 Feb;6(1):98-102. doi: 10.1002/ehf2.12377. Epub 2018 Nov 24.

7.

Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin: educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB).

Saenger AK, Jaffe AS, Body R, Collinson PO, Kavsak PA, Lam CSP, Lefèvre G, Omland T, Ordóñez-Llanos J, Pulkki K, Apple FS.

Clin Chem Lab Med. 2019 Apr 24;57(5):633-640. doi: 10.1515/cclm-2018-0905.

8.

Novel renal markers for the assessment of renal integrity in patients undergoing knee arthroplasty - a pilot study.

Piirainen A, Huopio J, Kokki H, Holopainen A, Pajunen T, Pulkki K, Kokki M.

J Exp Orthop. 2018 Sep 25;5(1):40. doi: 10.1186/s40634-018-0159-z.

9.

Impact of obesity on angiogenic and inflammatory markers in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort.

Jääskeläinen T, Heinonen S, Hämäläinen E, Pulkki K, Romppanen J, Laivuori H; FINNPEC.

Int J Obes (Lond). 2019 May;43(5):1070-1081. doi: 10.1038/s41366-018-0217-8. Epub 2018 Sep 25.

PMID:
30254363
10.

Interleukin-1 receptor antagonist as a biomarker of sepsis in neutropenic haematological patients.

Intke C, Korpelainen S, Hämäläinen S, Vänskä M, Koivula I, Jantunen E, Pulkki K, Juutilainen A.

Eur J Haematol. 2018 Aug 12. doi: 10.1111/ejh.13161. [Epub ahead of print]

PMID:
30099772
11.

Novel Biomarker Candidates for Febrile Neutropenia in Hematological Patients Using Nontargeted Metabolomics.

Lappalainen M, Jokkala J, Juutilainen A, Hämäläinen S, Koivula I, Jantunen E, Hanhineva K, Pulkki K.

Dis Markers. 2018 Apr 12;2018:6964529. doi: 10.1155/2018/6964529. eCollection 2018.

12.

Angiogenic profile in the Finnish Genetics of Pre-Eclampsia Consortium (FINNPEC) cohort.

Jääskeläinen T, Heinonen S, Hämäläinen E, Pulkki K, Romppanen J, Laivuori H; FINNPEC.

Pregnancy Hypertens. 2018 Oct;14:252-259. doi: 10.1016/j.preghy.2018.03.004. Epub 2018 Mar 10.

PMID:
29803331
13.

Quantifying Atherogenic Lipoproteins: Current and Future Challenges in the Era of Personalized Medicine and Very Low Concentrations of LDL Cholesterol. A Consensus Statement from EAS and EFLM.

Langlois MR, Chapman MJ, Cobbaert C, Mora S, Remaley AT, Ros E, Watts GF, Borén J, Baum H, Bruckert E, Catapano A, Descamps OS, von Eckardstein A, Kamstrup PR, Kolovou G, Kronenberg F, Langsted A, Pulkki K, Rifai N, Sypniewska G, Wiklund O, Nordestgaard BG; European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Joint Consensus Initiative.

Clin Chem. 2018 Jul;64(7):1006-1033. doi: 10.1373/clinchem.2018.287037. Epub 2018 May 14.

14.

The usage of procalcitonin in Finland.

Tujula B, Kokki M, Pulkki K, Romppanen J, Sjövall S, Tuominen H, Kokki H.

Acta Anaesthesiol Scand. 2018 Apr 19. doi: 10.1111/aas.13135. [Epub ahead of print]

PMID:
29675987
15.

Opinion: redefining the role of the physician in laboratory medicine in the context of emerging technologies, personalised medicine and patient autonomy ('4P medicine').

Orth M, Averina M, Chatzipanagiotou S, Faure G, Haushofer A, Kusec V, Machado A, Misbah SA, Oosterhuis W, Pulkki K, Twomey PJ, Wieland E.

J Clin Pathol. 2019 Mar;72(3):191-197. doi: 10.1136/jclinpath-2017-204734. Epub 2017 Dec 22.

16.

Camelina Sativa Oil, but not Fatty Fish or Lean Fish, Improves Serum Lipid Profile in Subjects with Impaired Glucose Metabolism-A Randomized Controlled Trial.

Schwab US, Lankinen MA, de Mello VD, Manninen SM, Kurl S, Pulkki KJ, Laaksonen DE, Erkkilä AT.

Mol Nutr Food Res. 2018 Feb;62(4). doi: 10.1002/mnfr.201700503. Epub 2018 Jan 31.

PMID:
29272068
17.

Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset Preeclampsia.

Kaartokallio T, Utge S, Klemetti MM, Paananen J, Pulkki K, Romppanen J, Tikkanen I, Heinonen S, Kajantie E, Kere J, Kivinen K, Pouta A, Lakkisto P, Laivuori H.

Hypertension. 2018 Jan;71(1):95-102. doi: 10.1161/HYPERTENSIONAHA.117.10425. Epub 2017 Dec 4.

PMID:
29203625
18.
19.

Acute kidney injury in cardiogenic shock: definitions, incidence, haemodynamic alterations, and mortality.

Tarvasmäki T, Haapio M, Mebazaa A, Sionis A, Silva-Cardoso J, Tolppanen H, Lindholm MG, Pulkki K, Parissis J, Harjola VP, Lassus J; CardShock Study Investigators.

Eur J Heart Fail. 2018 Mar;20(3):572-581. doi: 10.1002/ejhf.958. Epub 2017 Sep 27. No abstract available.

20.

Soluble CD14 as a Diagnostic and Prognostic Biomarker in Hematological Patients with Febrile Neutropenia.

Korpelainen S, Intke C, Hämäläinen S, Jantunen E, Juutilainen A, Pulkki K.

Dis Markers. 2017;2017:9805609. doi: 10.1155/2017/9805609. Epub 2017 Aug 6.

21.

Frequency and Prognostic Significance of Abnormal Liver Function Tests in Patients With Cardiogenic Shock.

Jäntti T, Tarvasmäki T, Harjola VP, Parissis J, Pulkki K, Sionis A, Silva-Cardoso J, Køber L, Banaszewski M, Spinar J, Fuhrmann V, Tolonen J, Carubelli V, diSomma S, Mebazaa A, Lassus J; CardShock investigators.

Am J Cardiol. 2017 Oct 1;120(7):1090-1097. doi: 10.1016/j.amjcard.2017.06.049. Epub 2017 Jul 14.

PMID:
28821350
22.

vWF correlates with visceral and pericardial adipose tissue in patients with a recent stroke of suspected cardiogenic etiology.

Muuronen AT, Taina M, Onatsu J, Korhonen M, Pulkki K, Jäkälä P, Vanninen R, Mustonen P.

PLoS One. 2017 Jun 1;12(6):e0178508. doi: 10.1371/journal.pone.0178508. eCollection 2017.

23.

Angiogenic profile and smoking in the Finnish Genetics of Pre-Eclampsia Consortium (FINNPEC) cohort.

Jääskeläinen T, Suomalainen-König S, Hämäläinen E, Pulkki K, Romppanen J, Heinonen S, Laivuori H; FINNPEC.

Ann Med. 2017 Nov;49(7):593-602. doi: 10.1080/07853890.2017.1335427. Epub 2017 Jun 9.

PMID:
28537456
24.

Soluble Urokinase-type Plasminogen Activator Receptor Predicts All-cause 5-Year Mortality in Ischemic Stroke and TIA.

Onatsu J, Taina M, Mustonen P, Hedman M, Muuronen A, Arponen O, Korhonen M, Jäkälä P, Vanninen R, Pulkki K.

In Vivo. 2017 May-Jun;31(3):381-386.

25.

Combined Measurement of Soluble ST2 and Amino-Terminal Pro-B-Type Natriuretic Peptide Provides Early Assessment of Severity in Cardiogenic Shock Complicating Acute Coronary Syndrome.

Tolppanen H, Rivas-Lasarte M, Lassus J, Sadoune M, Gayat E, Pulkki K, Arrigo M, Krastinova E, Sionis A, Parissis J, Spinar J, Januzzi J, Harjola VP, Mebazaa A; CardShock Investigators.

Crit Care Med. 2017 Jul;45(7):e666-e673. doi: 10.1097/CCM.0000000000002336.

PMID:
28403119
26.

Asymmetric dimethylarginine in the assessment of febrile neutropenia in hematological patients.

Lappalainen M, Hämäläinen S, Juutilainen A, Koivula I, Pulkki K, Jantunen E.

Scand J Clin Lab Invest. 2017 Apr;77(2):130-134. doi: 10.1080/00365513.2017.1286518.

PMID:
28218011
27.

Does Rectus Sheath Block Analgesia Alter Levels of the Oxidative Stress Biomarker Glutathione Peroxidase: A Randomised Trial of Patients with Cancer and Benign Disease.

Purdy M, Kärkkäinen J, Kokki M, Anttila M, Aspinen S, Juvonen P, Kokki H, Pulkki K, Rantanen T, Eskelinen M.

Anticancer Res. 2017 Feb;37(2):897-902.

PMID:
28179349
28.

Adrenomedullin: a marker of impaired hemodynamics, organ dysfunction, and poor prognosis in cardiogenic shock.

Tolppanen H, Rivas-Lasarte M, Lassus J, Sans-Roselló J, Hartmann O, Lindholm M, Arrigo M, Tarvasmäki T, Köber L, Thiele H, Pulkki K, Spinar J, Parissis J, Banaszewski M, Silva-Cardoso J, Carubelli V, Sionis A, Harjola VP, Mebazaa A.

Ann Intensive Care. 2017 Dec;7(1):6. doi: 10.1186/s13613-016-0229-2. Epub 2017 Jan 4.

29.

How Well Do Laboratories Adhere to Recommended Clinical Guidelines for the Management of Myocardial Infarction: The CARdiac MArker Guidelines Uptake in Europe Study (CARMAGUE).

Collinson P, Hammerer-Lercher A, Suvisaari J, Apple FS, Christenson RH, Pulkki K, van Dieijen-Visser MP, Duff CJ, Baum H, Stavljenic-Rukavina A, Aakre KM, Langlois MR, Stankovic S, Laitinen P; Working Group for Cardiac Markers, European Federation of Clinical Chemistry and Laboratory Medicine.

Clin Chem. 2016 Sep;62(9):1264-71. doi: 10.1373/clinchem.2016.259515. Epub 2016 Jul 26.

30.

The plasma 8-OHdG levels and oxidative stress following cholecystectomy: a randomised multicentre study of patients with minilaparotomy cholecystectomy versus laparoscopic cholecystectomy.

Aspinen S, Harju J, Juvonen P, Selander T, Kokki H, Pulkki K, Eskelinen MJ.

Scand J Gastroenterol. 2016 Dec;51(12):1507-1511. Epub 2016 Jul 19.

PMID:
27435790
31.

Fasting Is Not Routinely Required for Determination of a Lipid Profile: Clinical and Laboratory Implications Including Flagging at Desirable Concentration Cutpoints-A Joint Consensus Statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine.

Nordestgaard BG, Langsted A, Mora S, Kolovou G, Baum H, Bruckert E, Watts GF, Sypniewska G, Wiklund O, Borén J, Chapman MJ, Cobbaert C, Descamps OS, von Eckardstein A, Kamstrup PR, Pulkki K, Kronenberg F, Remaley AT, Rifai N, Ros E, Langlois M; European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Joint Consensus Initiative.

Clin Chem. 2016 Jul;62(7):930-46. doi: 10.1373/clinchem.2016.258897. Epub 2016 May 27.

32.

Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points-a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine.

Nordestgaard BG, Langsted A, Mora S, Kolovou G, Baum H, Bruckert E, Watts GF, Sypniewska G, Wiklund O, Borén J, Chapman MJ, Cobbaert C, Descamps OS, von Eckardstein A, Kamstrup PR, Pulkki K, Kronenberg F, Remaley AT, Rifai N, Ros E, Langlois M; European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) joint consensus initiative.

Eur Heart J. 2016 Jul 1;37(25):1944-58. doi: 10.1093/eurheartj/ehw152. Epub 2016 Apr 26.

33.

Does Post-Surgery Placement of Rectus Sheath Block Analgesia Alter the Oxidative Stress Biomarker 8-OHdG Concentrations: A Randomised Trial of Patients with Cancer and Benign Disease.

Purdy M, Kokki M, Anttila M, Aspinen S, Juvonen P, Selander T, Kokki H, Pulkki K, Eskelinen M.

Cancer Genomics Proteomics. 2016 May-Jun;13(3):239-44.

PMID:
27107066
34.

The Cerebrospinal Fluid Distribution of Postoperatively Administred Dexketoprofen and Etoricoxib and Their Effect on Pain and Inflammatory Markers in Patients Undergoing Hip Arthroplasty.

Piirainen A, Kokki M, Hautajärvi H, Lehtonen M, Miettinen H, Pulkki K, Ranta VP, Kokki H.

Clin Drug Investig. 2016 Jul;36(7):545-55. doi: 10.1007/s40261-016-0400-4.

PMID:
27086319
35.

Inflammatory response to surgical trauma in patients with minilaparotomy cholecystectomy versus laparoscopic cholecystectomy: a randomised multicentre study.

Aspinen S, Kinnunen M, Harju J, Juvonen P, Selander T, Holopainen A, Kokki H, Pulkki K, Eskelinen M.

Scand J Gastroenterol. 2016;51(6):739-44. doi: 10.3109/00365521.2015.1129436. Epub 2016 Jan 13.

PMID:
26758677
36.

Biomarkers of neutropenic sepsis.

Jantunen E, Juutilainen A, Hämäläinen S, Koivula I, Vänskä M, Purhonen AK, Pulkki K.

Duodecim. 2016;132(21):1946-51. Review.

PMID:
29190045
37.

Glucose Metabolism Effects of Vitamin D in Prediabetes: The VitDmet Randomized Placebo-Controlled Supplementation Study.

Tuomainen TP, Virtanen JK, Voutilainen S, Nurmi T, Mursu J, de Mello VD, Schwab U, Hakumäki M, Pulkki K, Uusitupa M.

J Diabetes Res. 2015;2015:672653. doi: 10.1155/2015/672653. Epub 2015 May 27.

38.

Acute phase IL-10 plasma concentration associates with the high risk sources of cardiogenic stroke.

Arponen O, Muuronen A, Taina M, Sipola P, Hedman M, Jäkälä P, Vanninen R, Pulkki K, Mustonen P.

PLoS One. 2015 Apr 29;10(4):e0120910. doi: 10.1371/journal.pone.0120910. eCollection 2015.

39.

Human plasma cell-free DNA as a predictor of infectious complications of neutropenic fever in hematological patients.

Purhonen AK, Juutilainen A, Vänskä M, Lehtikangas M, Lakkisto P, Hämäläinen S, Koivula I, Jantunen E, Pulkki K.

Infect Dis (Lond). 2015 Apr;47(4):255-9. doi: 10.3109/00365548.2014.985711. Epub 2015 Feb 9.

PMID:
25664374
40.

Admission interleukin-6 is associated with post resuscitation organ dysfunction and predicts long-term neurological outcome after out-of-hospital ventricular fibrillation.

Vaahersalo J, Skrifvars MB, Pulkki K, Stridsberg M, Røsjø H, Hovilehto S, Tiainen M, Varpula T, Pettilä V, Ruokonen E; FINNRESUSCI Laboratory Study Group.

Resuscitation. 2014 Nov;85(11):1573-9. doi: 10.1016/j.resuscitation.2014.08.036. Epub 2014 Sep 17.

PMID:
25238742
41.

Combination of LC-MS/MS aldosterone and automated direct renin in screening for primary aldosteronism.

Juutilainen A, Savolainen K, Romppanen J, Turpeinen U, Hämäläinen E, Kemppainen J, Moilanen L, Pulkki K.

Clin Chim Acta. 2014 Jun 10;433:209-15. doi: 10.1016/j.cca.2014.03.015. Epub 2014 Mar 22.

PMID:
24661979
42.

Clinical impact of direct HDLc and LDLc method bias in hypertriglyceridemia. A simulation study of the EAS-EFLM Collaborative Project Group.

Langlois MR, Descamps OS, van der Laarse A, Weykamp C, Baum H, Pulkki K, von Eckardstein A, De Bacquer D, Borén J, Wiklund O, Laitinen P, Oosterhuis WP, Cobbaert C; EAS-EFLM Collaborative Project.

Atherosclerosis. 2014 Mar;233(1):83-90. doi: 10.1016/j.atherosclerosis.2013.12.016. Epub 2014 Jan 4.

PMID:
24529127
43.

Serum hyperglycosylated human chorionic gonadotrophin at 14-17 weeks of gestation does not predict preeclampsia.

Keikkala E, Ranta JK, Vuorela P, Leinonen R, Laivuori H, Väisänen S, Marttala J, Romppanen J, Pulkki K, Stenman UH, Heinonen S.

Prenat Diagn. 2014 Jul;34(7):699-705. doi: 10.1002/pd.4335. Epub 2014 Feb 17.

PMID:
24464955
44.

Primary vitamin D target genes allow a categorization of possible benefits of vitamin D₃ supplementation.

Carlberg C, Seuter S, de Mello VD, Schwab U, Voutilainen S, Pulkki K, Nurmi T, Virtanen J, Tuomainen TP, Uusitupa M.

PLoS One. 2013 Jul 29;8(7):e71042. doi: 10.1371/journal.pone.0071042. Print 2013.

45.

The role of cardiorenal biomarkers for risk stratification in the early follow-up after hospitalisation for acute heart failure.

Tolonen J, Lassus JP, Siirila-Waris K, Tarvasmäki T, Pulkki K, Sund R, Peuhkurinen K, Nieminen MS, Harjola VP; FINN-AKVA Study Group.

Biomarkers. 2013 Sep;18(6):525-31. doi: 10.3109/1354750X.2013.821522. Epub 2013 Jul 23.

PMID:
23879546
46.

Soluble form of urokinase-type plasminogen activator receptor as a diagnostic and prognostic marker in hematological patients with neutropenic fever.

Vänskä M, Purhonen AK, Koivula I, Jantunen E, Hämäläinen S, Pulkki K, Juutilainen A.

Leuk Lymphoma. 2014 Mar;55(3):718-21. doi: 10.3109/10428194.2013.811582. Epub 2013 Jul 22. No abstract available.

PMID:
23734690
47.

Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome -- a randomized study (SYSDIET).

Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Mortensen LS, Cloetens L, Johansson-Persson A, Onning G, Landin-Olsson M, Herzig KH, Hukkanen J, Rosqvist F, Iggman D, Paananen J, Pulkki KJ, Siloaho M, Dragsted L, Barri T, Overvad K, Bach Knudsen KE, Hedemann MS, Arner P, Dahlman I, Borge GI, Baardseth P, Ulven SM, Gunnarsdottir I, Jónsdóttir S, Thorsdottir I, Orešič M, Poutanen KS, Risérus U, Akesson B.

J Intern Med. 2013 Jul;274(1):52-66. doi: 10.1111/joim.12044. Epub 2013 Mar 2.

48.

Do laboratories follow heart failure recommendations and guidelines and did we improve? The CARdiac MArker Guideline Uptake in Europe (CARMAGUE).

Hammerer-Lercher A, Collinson P, van Dieijen-Visser MP, Pulkki K, Suvisaari J, Ravkilde J, Stavljenic-Rukavina A, Baum H, Laitinen P.

Clin Chem Lab Med. 2013 Jun;51(6):1301-6. doi: 10.1515/cclm-2012-0510.

PMID:
23334056
49.

Long-term survival after hospitalization for acute heart failure--differences in prognosis of acutely decompensated chronic and new-onset acute heart failure.

Lassus JP, Siirilä-Waris K, Nieminen MS, Tolonen J, Tarvasmäki T, Peuhkurinen K, Melin J, Pulkki K, Harjola VP; FINN-AKVA study group.

Int J Cardiol. 2013 Sep 20;168(1):458-62. doi: 10.1016/j.ijcard.2012.09.128. Epub 2012 Oct 13.

PMID:
23073273
50.

IL-10 combined with procalcitonin improves early prediction of complications of febrile neutropenia in hematological patients.

Vänskä M, Koivula I, Jantunen E, Hämäläinen S, Purhonen AK, Pulkki K, Juutilainen A.

Cytokine. 2012 Dec;60(3):787-92. doi: 10.1016/j.cyto.2012.07.023. Epub 2012 Aug 17.

PMID:
22902948

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