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Items: 47


Identification of Pre-frailty Sub-Phenotypes in Elderly Using Metabolomics.

Pujos-Guillot E, Pétéra M, Jacquemin J, Centeno D, Lyan B, Montoliu I, Madej D, Pietruszka B, Fabbri C, Santoro A, Brzozowska A, Franceschi C, Comte B.

Front Physiol. 2019 Jan 24;9:1903. doi: 10.3389/fphys.2018.01903. eCollection 2018.


Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies.

Ulaszewska MM, Weinert CH, Trimigno A, Portmann R, Andres Lacueva C, Badertscher R, Brennan L, Brunius C, Bub A, Capozzi F, Cialiè Rosso M, Cordero CE, Daniel H, Durand S, Egert B, Ferrario PG, Feskens EJM, Franceschi P, Garcia-Aloy M, Giacomoni F, Giesbertz P, González-Domínguez R, Hanhineva K, Hemeryck LY, Kopka J, Kulling SE, Llorach R, Manach C, Mattivi F, Migné C, Münger LH, Ott B, Picone G, Pimentel G, Pujos-Guillot E, Riccadonna S, Rist MJ, Rombouts C, Rubert J, Skurk T, Sri Harsha PSC, Van Meulebroek L, Vanhaecke L, Vázquez-Fresno R, Wishart D, Vergères G.

Mol Nutr Food Res. 2019 Jan;63(1):e1800384. doi: 10.1002/mnfr.201800384. Epub 2018 Oct 11. Review.


Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption.

Martin OCB, Naud N, Taché S, Debrauwer L, Chevolleau S, Dupuy J, Chantelauze C, Durand D, Pujos-Guillot E, Blas-Y-Estrada F, Urbano C, Kuhnle GGC, Santé-Lhoutellier V, Sayd T, Viala D, Blot A, Meunier N, Schlich P, Attaix D, Guéraud F, Scislowski V, Corpet DE, Pierre FHF.

Cancer Prev Res (Phila). 2018 Sep;11(9):569-580. doi: 10.1158/1940-6207.CAPR-17-0361. Epub 2018 Jun 28.


Metabolomics Reveals that the Type of Protein in a High-Fat Meal Modulates Postprandial Mitochondrial Overload and Incomplete Substrate Oxidation in Healthy Overweight Men.

Pujos-Guillot E, Brandolini-Bunlon M, Fouillet H, Joly C, Martin JF, Huneau JF, Dardevet D, Mariotti F.

J Nutr. 2018 Jun 1;148(6):876-884. doi: 10.1093/jn/nxy049.


Exploratory GC/MS-Based Metabolomics of Body Fluids.

Migné C, Durand S, Pujos-Guillot E.

Methods Mol Biol. 2018;1730:239-246. doi: 10.1007/978-1-4939-7592-1_16.


Evaluation of oxidized phospholipids analysis by LC-MS/MS.

Khoury S, Pouyet C, Lyan B, Pujos-Guillot E.

Anal Bioanal Chem. 2018 Jan;410(2):633-647. doi: 10.1007/s00216-017-0764-1. Epub 2017 Nov 28.


Myofiber metabolic type determination by mass spectrometry imaging.

Centeno D, Vénien A, Pujos-Guillot E, Astruc T, Chambon C, Théron L.

J Mass Spectrom. 2017 Aug;52(8):493-496. doi: 10.1002/jms.3957.


Systems Metabolomics for Prediction of Metabolic Syndrome.

Pujos-Guillot E, Brandolini M, Pétéra M, Grissa D, Joly C, Lyan B, Herquelot É, Czernichow S, Zins M, Goldberg M, Comte B.

J Proteome Res. 2017 Jun 2;16(6):2262-2272. doi: 10.1021/acs.jproteome.7b00116. Epub 2017 May 4.


A Proof of Concept to Bridge the Gap between Mass Spectrometry Imaging, Protein Identification and Relative Quantitation: MSI~LC-MS/MS-LF.

Théron L, Centeno D, Coudy-Gandilhon C, Pujos-Guillot E, Astruc T, Rémond D, Barthelemy JC, Roche F, Feasson L, Hébraud M, Béchet D, Chambon C.

Proteomes. 2016 Oct 26;4(4). pii: E32. doi: 10.3390/proteomes4040032.


Weight for gestational age and metabolically healthy obesity in adults from the Haguenau cohort.

Matta J, Carette C, Levy Marchal C, Bertrand J, Pétéra M, Zins M, Pujos-Guillot E, Comte B, Czernichow S.

BMJ Open. 2016 Aug 31;6(8):e011367. doi: 10.1136/bmjopen-2016-011367.


Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs.

Polakof S, Rémond D, Bernalier-Donadille A, Rambeau M, Pujos-Guillot E, Comte B, Dardevet D, Savary-Auzeloux I.

Eur J Nutr. 2018 Feb;57(1):119-135. doi: 10.1007/s00394-016-1302-1. Epub 2016 Aug 27.


Variations in the metabolome in response to disease activity of rheumatoid arthritis.

Tatar Z, Migne C, Petera M, Gaudin P, Lequerre T, Marotte H, Tebib J, Pujos Guillot E, Soubrier M.

BMC Musculoskelet Disord. 2016 Aug 22;17(1):353. doi: 10.1186/s12891-016-1214-5.


Dietary intake in young adults born small or appropriate for gestational age: data from the Haguenau cohort.

Matta J, Carette C, Levy Marchal C, Bertrand J, Pétéra M, Zins M, Pujos-Guillot E, Comte B, Czernichow S.

BMJ Open. 2016 Jul 29;6(7):e012309. doi: 10.1136/bmjopen-2016-012309.


Feature Selection Methods for Early Predictive Biomarker Discovery Using Untargeted Metabolomic Data.

Grissa D, Pétéra M, Brandolini M, Napoli A, Comte B, Pujos-Guillot E.

Front Mol Biosci. 2016 Jul 8;3:30. doi: 10.3389/fmolb.2016.00030. eCollection 2016.


Quantification of 4-hydroxy-2-nonenal-protein adducts in the in vivo gastric digesta of mini-pigs using a GC-MS/MS method with accuracy profile validation.

Delosière M, Santé-Lhoutellier V, Chantelauze C, Durand D, Thomas A, Joly C, Pujos-Guillot E, Rémond D, Comte B, Gladine C, Guy A, Durand T, Laurentie M, Dufour C.

Food Funct. 2016 Aug 10;7(8):3497-504. doi: 10.1039/c6fo00413j. Epub 2016 Jul 15.


Time Course of Molecular and Metabolic Events in the Development of Insulin Resistance in Fructose-Fed Rats.

Polakof S, Dardevet D, Lyan B, Mosoni L, Gatineau E, Martin JF, Pujos-Guillot E, Mazur A, Comte B.

J Proteome Res. 2016 Jun 3;15(6):1862-74. doi: 10.1021/acs.jproteome.6b00043. Epub 2016 May 4.


Red meat and colorectal cancer: Nrf2-dependent antioxidant response contributes to the resistance of preneoplastic colon cells to fecal water of hemoglobin- and beef-fed rats.

Surya R, Héliès-Toussaint C, Martin OC, Gauthier T, Guéraud F, Taché S, Naud N, Jouanin I, Chantelauze C, Durand D, Joly C, Pujos-Guillot E, Pierre FH, Huc L.

Carcinogenesis. 2016 Jun;37(6):635-645. doi: 10.1093/carcin/bgw035. Epub 2016 Mar 18.


Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.

Shoaie S, Ghaffari P, Kovatcheva-Datchary P, Mardinoglu A, Sen P, Pujos-Guillot E, de Wouters T, Juste C, Rizkalla S, Chilloux J, Hoyles L, Nicholson JK; MICRO-Obes Consortium, Dore J, Dumas ME, Clement K, Bäckhed F, Nielsen J.

Cell Metab. 2015 Aug 4;22(2):320-31. doi: 10.1016/j.cmet.2015.07.001.


Can we trust untargeted metabolomics? Results of the metabo-ring initiative, a large-scale, multi-instrument inter-laboratory study.

Martin JC, Maillot M, Mazerolles G, Verdu A, Lyan B, Migné C, Defoort C, Canlet C, Junot C, Guillou C, Manach C, Jabob D, Bouveresse DJ, Paris E, Pujos-Guillot E, Jourdan F, Giacomoni F, Courant F, Favé G, Le Gall G, Chassaigne H, Tabet JC, Martin JF, Antignac JP, Shintu L, Defernez M, Philo M, Alexandre-Gouaubau MC, Amiot-Carlin MJ, Bossis M, Triba MN, Stojilkovic N, Banzet N, Molinié R, Bott R, Goulitquer S, Caldarelli S, Rutledge DN.

Metabolomics. 2015;11(4):807-821. Epub 2014 Oct 14.


Assessment of protein modifications in liver of rats under chronic treatment with paracetamol (acetaminophen) using two complementary mass spectrometry-based metabolomic approaches.

Mast C, Lyan B, Joly C, Centeno D, Giacomoni F, Martin JF, Mosoni L, Dardevet D, Pujos-Guillot E, Papet I.

J Proteomics. 2015 Apr 29;120:194-203. doi: 10.1016/j.jprot.2015.03.014. Epub 2015 Mar 24.


Cyclic fatty acids found in frying oils are detoxified via classical drug metabolic pathway but also by β-oxidation and eliminated as conjugates in rats.

Desmarais A, Pujos-Guillot E, Lyan B, Martin JF, Leblanc N, Angers P, Sébédio JL.

Lipids. 2015 Apr;50(4):381-96. doi: 10.1007/s11745-015-3997-9. Epub 2015 Mar 5.


Development of a LC-MS/MS method for the simultaneous screening of seven water-soluble vitamins in processing semi-coarse wheat flour products.

Nurit E, Lyan B, Piquet A, Branlard G, Pujos-Guillot E.

Anal Bioanal Chem. 2015 May;407(12):3471-9. doi: 10.1007/s00216-015-8553-1. Epub 2015 Feb 21.


Specific appetite, energetic and metabolomics responses to fat overfeeding in resistant-to-bodyweight-gain constitutional thinness.

Germain N, Galusca B, Caron-Dorval D, Martin JF, Pujos-Guillot E, Boirie Y, Khalfallah Y, Ling Y, Minnion JS, Bloom SR, Epelbaum J, Estour B.

Nutr Diabetes. 2014 Jul 14;4:e126. doi: 10.1038/nutd.2014.17.


New biomarkers of coffee consumption identified by the non-targeted metabolomic profiling of cohort study subjects.

Rothwell JA, Fillâtre Y, Martin JF, Lyan B, Pujos-Guillot E, Fezeu L, Hercberg S, Comte B, Galan P, Touvier M, Manach C.

PLoS One. 2014 Apr 8;9(4):e93474. doi: 10.1371/journal.pone.0093474. eCollection 2014.


Lipid profiling following intake of the omega 3 fatty acid DHA identifies the peroxidized metabolites F4-neuroprostanes as the best predictors of atherosclerosis prevention.

Gladine C, Newman JW, Durand T, Pedersen TL, Galano JM, Demougeot C, Berdeaux O, Pujos-Guillot E, Mazur A, Comte B.

PLoS One. 2014 Feb 18;9(2):e89393. doi: 10.1371/journal.pone.0089393. eCollection 2014.


Untargeted metabolomics as a screening tool for estimating compliance to a dietary pattern.

Andersen MB, Rinnan Å, Manach C, Poulsen SK, Pujos-Guillot E, Larsen TM, Astrup A, Dragsted LO.

J Proteome Res. 2014 Mar 7;13(3):1405-18. doi: 10.1021/pr400964s. Epub 2014 Feb 6.


Discovery and validation of urinary exposure markers for different plant foods by untargeted metabolomics.

Andersen MB, Kristensen M, Manach C, Pujos-Guillot E, Poulsen SK, Larsen TM, Astrup A, Dragsted L.

Anal Bioanal Chem. 2014 Mar;406(7):1829-44. doi: 10.1007/s00216-013-7498-5. Epub 2014 Jan 4.


Resistant starch intake partly restores metabolic and inflammatory alterations in the liver of high-fat-diet-fed rats.

Polakof S, Díaz-Rubio ME, Dardevet D, Martin JF, Pujos-Guillot E, Scalbert A, Sebedio JL, Mazur A, Comte B.

J Nutr Biochem. 2013 Nov;24(11):1920-30. doi: 10.1016/j.jnutbio.2013.05.008. Epub 2013 Sep 3.


Mass spectrometry-based metabolomics for the discovery of biomarkers of fruit and vegetable intake: citrus fruit as a case study.

Pujos-Guillot E, Hubert J, Martin JF, Lyan B, Quintana M, Claude S, Chabanas B, Rothwell JA, Bennetau-Pelissero C, Scalbert A, Comte B, Hercberg S, Morand C, Galan P, Manach C.

J Proteome Res. 2013 Apr 5;12(4):1645-59. doi: 10.1021/pr300997c. Epub 2013 Mar 5.


Simultaneous analysis of the main markers of nitrogen status in dairy cow's urine using hydrophilic interaction chromatography and tandem mass spectrometry detection.

Boudra H, Doreau M, Noziere P, Pujos-Guillot E, Morgavi DP.

J Chromatogr A. 2012 Sep 21;1256:169-76. doi: 10.1016/j.chroma.2012.07.094. Epub 2012 Aug 4.


Acetaminophen metabolism after major surgery: a greater challenge with increasing age.

Pickering G, Schneider E, Papet I, Pujos-Guillot E, Pereira B, Simen E, Dubray C, Schoeffler P.

Clin Pharmacol Ther. 2011 Nov;90(5):707-11. doi: 10.1038/clpt.2011.176. Epub 2011 Oct 5.


Increasing intake of long-chain n-3 PUFA enhances lipoperoxidation and modulates hepatic gene expression in a dose-dependent manner.

Gladine C, Roy NC, Rigaudière JP, Laillet B, Da Silva G, Joly C, Pujos-Guillot E, Morio B, Feillet-Coudray C, McNabb WC, Chardigny JM, Comte B.

Br J Nutr. 2012 May;107(9):1254-73. doi: 10.1017/S0007114511004259. Epub 2011 Sep 14.


Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat.

Momken I, Stevens L, Bergouignan A, Desplanches D, Rudwill F, Chery I, Zahariev A, Zahn S, Stein TP, Sebedio JL, Pujos-Guillot E, Falempin M, Simon C, Coxam V, Andrianjafiniony T, Gauquelin-Koch G, Picquet F, Blanc S.

FASEB J. 2011 Oct;25(10):3646-60. doi: 10.1096/fj.10-177295. Epub 2011 Jun 29.


Disruption of chronic cariporide treatment abrogates myocardial ion homeostasis during acute ischemia reperfusion.

Bourahla V, Dubouchaud H, Mourmoura E, Vitiello D, Faure P, Migné C, Pujos-Guillot E, Richardson M, Demaison L.

J Cardiovasc Pharmacol. 2011 Sep;58(3):284-94. doi: 10.1097/FJC.0b013e318223ebb2.


Therapeutic paracetamol treatment in older persons induces dietary and metabolic modifications related to sulfur amino acids.

Pujos-Guillot E, Pickering G, Lyan B, Ducheix G, Brandolini-Bunlon M, Glomot F, Dardevet D, Dubray C, Papet I.

Age (Dordr). 2012 Feb;34(1):181-93. doi: 10.1007/s11357-011-9218-4. Epub 2011 Feb 22.


Enterohaemorrhagic Escherichia coli gains a competitive advantage by using ethanolamine as a nitrogen source in the bovine intestinal content.

Bertin Y, Girardeau JP, Chaucheyras-Durand F, Lyan B, Pujos-Guillot E, Harel J, Martin C.

Environ Microbiol. 2011 Feb;13(2):365-77. doi: 10.1111/j.1462-2920.2010.02334.x. Epub 2010 Sep 16.


Variation in content and composition of phenolic compounds in permanent pastures according to botanical variation.

Reynaud A, Fraisse D, Cornu A, Farruggia A, Pujos-Guillot E, Besle JM, Martin B, Lamaison JL, Paquet D, Doreau M, Graulet B.

J Agric Food Chem. 2010 May 12;58(9):5485-94. doi: 10.1021/jf1000293.


Effects of fish oil and starch added to a diet containing sunflower-seed oil on dairy goat performance, milk fatty acid composition and in vivo delta9-desaturation of [13C]vaccenic acid.

Bernard L, Mouriot J, Rouel J, Glasser F, Capitan P, Pujos-Guillot E, Chardigny JM, Chilliard Y.

Br J Nutr. 2010 Aug;104(3):346-54. doi: 10.1017/S0007114510000486. Epub 2010 Mar 22.


Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research.

Scalbert A, Brennan L, Fiehn O, Hankemeier T, Kristal BS, van Ommen B, Pujos-Guillot E, Verheij E, Wishart D, Wopereis S.

Metabolomics. 2009 Dec;5(4):435-458. Epub 2009 Jun 12.


Metabolite analysis of human fecal water by gas chromatography/mass spectrometry with ethyl chloroformate derivatization.

Gao X, Pujos-Guillot E, Martin JF, Galan P, Juste C, Jia W, Sebedio JL.

Anal Biochem. 2009 Oct 15;393(2):163-75. doi: 10.1016/j.ab.2009.06.036. Epub 2009 Jun 30.


Metabolomics in evaluation of glucose disorders.

Sébédio JL, Pujos-Guillot E, Ferrara M.

Curr Opin Clin Nutr Metab Care. 2009 Jul;12(4):412-8. doi: 10.1097/MCO.0b013e32832c97c3. Review.


Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats.

Balage M, Averous J, Rémond D, Bos C, Pujos-Guillot E, Papet I, Mosoni L, Combaret L, Dardevet D.

J Nutr Biochem. 2010 Apr;21(4):325-31. doi: 10.1016/j.jnutbio.2009.01.005. Epub 2009 Apr 14.


The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation.

Baccini M, Bachmaier EM, Biggeri A, Boekschoten MV, Bouwman FG, Brennan L, Caesar R, Cinti S, Coort SL, Crosley K, Daniel H, Drevon CA, Duthie S, Eijssen L, Elliott RM, van Erk M, Evelo C, Gibney M, Heim C, Horgan GW, Johnson IT, Kelder T, Kleemann R, Kooistra T, van Iersel MP, Mariman EC, Mayer C, McLoughlin G, Müller M, Mulholland F, van Ommen B, Polley AC, Pujos-Guillot E, Rubio-Aliaga I, Roche HM, de Roos B, Sailer M, Tonini G, Williams LM, de Wit N; NuGO PPS Team.

Genes Nutr. 2008 Dec;3(3-4):147-51. doi: 10.1007/s12263-008-0102-5. Epub 2008 Nov 26. No abstract available.


Metabolomics provide new insight on the metabolism of dietary phytochemicals in rats.

Fardet A, Llorach R, Orsoni A, Martin JF, Pujos-Guillot E, Lapierre C, Scalbert A.

J Nutr. 2008 Jul;138(7):1282-7.


A liquid chromatography-quadrupole time-of-flight (LC-QTOF)-based metabolomic approach reveals new metabolic effects of catechin in rats fed high-fat diets.

Fardet A, Llorach R, Martin JF, Besson C, Lyan B, Pujos-Guillot E, Scalbert A.

J Proteome Res. 2008 Jun;7(6):2388-98. doi: 10.1021/pr800034h. Epub 2008 May 17.


Influence of acute phytochemical intake on human urinary metabolomic profiles.

Walsh MC, Brennan L, Pujos-Guillot E, Sébédio JL, Scalbert A, Fagan A, Higgins DG, Gibney MJ.

Am J Clin Nutr. 2007 Dec;86(6):1687-93.


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