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Items: 1 to 50 of 161

1.

Toxicokinetics and tolerance of a high energy material 3,4,5-trinitropyrazole (TNP) in mice.

Guyot L, Honorat M, Jacob G, Bardel C, Tod M, Puisieux A, Guitton J, Payen L.

Toxicol Appl Pharmacol. 2018 Jun 26;355:103-111. doi: 10.1016/j.taap.2018.06.023. [Epub ahead of print]

PMID:
29959026
2.

Metabolomics and cytotoxicity of monomethylhydrazine (MMH) and (E)-1,1,4,4-tetramethyl-2-tetrazene (TMTZ), two liquid propellants.

Guyot L, Machon C, Honorat M, Manship B, Bouard C, Vigneron A, Puisieux A, Labarthe E, Jacob G, Dhenain A, Guitton J, Payen L.

Toxicol In Vitro. 2018 Jun 7;52:70-86. doi: 10.1016/j.tiv.2018.06.005. [Epub ahead of print]

PMID:
29885439
3.

Integrated analysis highlights APC11 protein expression as a likely new independent predictive marker for colorectal cancer.

Drouet Y, Treilleux I, Viari A, Léon S, Devouassoux-Shisheboran M, Voirin N, de la Fouchardière C, Manship B, Puisieux A, Lasset C, Moyret-Lalle C.

Sci Rep. 2018 May 9;8(1):7386. doi: 10.1038/s41598-018-25631-1.

4.

Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells.

Paquet-Fifield S, Koh SL, Cheng L, Beyit LM, Shembrey C, Mølck C, Behrenbruch C, Papin M, Gironella M, Guelfi S, Nasr R, Grillet F, Prudhomme M, Bourgaux JF, Castells A, Pascussi JM, Heriot AG, Puisieux A, Davis MJ, Pannequin J, Hill AF, Sloan EK, Hollande F.

Cancer Res. 2018 Jun 1;78(11):2925-2938. doi: 10.1158/0008-5472.CAN-17-1869. Epub 2018 Mar 6.

PMID:
29510994
5.

Cellular Pliancy and the Multistep Process of Tumorigenesis.

Puisieux A, Pommier RM, Morel AP, Lavial F.

Cancer Cell. 2018 Feb 12;33(2):164-172. doi: 10.1016/j.ccell.2018.01.007. Review.

PMID:
29438693
6.

Pleiotropic Roles for ZEB1 in Cancer.

Caramel J, Ligier M, Puisieux A.

Cancer Res. 2018 Jan 1;78(1):30-35. doi: 10.1158/0008-5472.CAN-17-2476. Epub 2017 Dec 18. Review.

PMID:
29254997
7.

[Epithelial-to-mesenchymal transition and cancer-initiating cells].

Ouzounova M, Puisieux A.

Bull Cancer. 2017 Dec;104(12):1068-1071. doi: 10.1016/j.bulcan.2017.10.011. Epub 2017 Nov 20. French. No abstract available.

PMID:
29157556
8.

The cell-of-origin dictates the genomic landscape of breast cancers.

Puisieux A, Pommier RM, Tissier A, Morel AP.

Mol Cell Oncol. 2017 Jun 16;4(4):e1338931. doi: 10.1080/23723556.2017.1338931. eCollection 2017.

9.

A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes.

Foy JP, Bazire L, Ortiz-Cuaran S, Deneuve S, Kielbassa J, Thomas E, Viari A, Puisieux A, Goudot P, Bertolus C, Foray N, Kirova Y, Verrelle P, Saintigny P.

BMC Med. 2017 Sep 1;15(1):165. doi: 10.1186/s12916-017-0929-y.

10.

Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach.

Bouard C, Terreux R, Tissier A, Jacqueroud L, Vigneron A, Ansieau S, Puisieux A, Payen L.

BMC Struct Biol. 2017 May 18;17(1):6. doi: 10.1186/s12900-017-0076-x.

11.

The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade.

Foy JP, Bertolus C, Michallet MC, Deneuve S, Incitti R, Bendriss-Vermare N, Albaret MA, Ortiz-Cuaran S, Thomas E, Colombe A, Py C, Gadot N, Michot JP, Fayette J, Viari A, Van den Eynde B, Goudot P, Devouassoux-Shisheboran M, Puisieux A, Caux C, Zrounba P, Lantuejoul S, Saintigny P.

Ann Oncol. 2017 Aug 1;28(8):1934-1941. doi: 10.1093/annonc/mdx210.

12.

A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability.

Morel AP, Ginestier C, Pommier RM, Cabaud O, Ruiz E, Wicinski J, Devouassoux-Shisheboran M, Combaret V, Finetti P, Chassot C, Pinatel C, Fauvet F, Saintigny P, Thomas E, Moyret-Lalle C, Lachuer J, Despras E, Jauffret JL, Bertucci F, Guitton J, Wierinckx A, Wang Q, Radosevic-Robin N, Penault-Llorca F, Cox DG, Hollande F, Ansieau S, Caramel J, Birnbaum D, Vigneron AM, Tissier A, Charafe-Jauffret E, Puisieux A.

Nat Med. 2017 May;23(5):568-578. doi: 10.1038/nm.4323. Epub 2017 Apr 10.

PMID:
28394329
13.

Splicing factor ratio as an index of epithelial-mesenchymal transition and tumor aggressiveness in breast cancer.

Fici P, Gallerani G, Morel AP, Mercatali L, Ibrahim T, Scarpi E, Amadori D, Puisieux A, Rigaud M, Fabbri F.

Oncotarget. 2017 Jan 10;8(2):2423-2436. doi: 10.18632/oncotarget.13682.

14.

[Contribution and challenges of Big Data in oncology].

Saintigny P, Foy JP, Ferrari A, Cassier P, Viari A, Puisieux A.

Bull Cancer. 2017 Mar;104(3):281-287. doi: 10.1016/j.bulcan.2016.10.020. Epub 2016 Nov 25. Review. French.

PMID:
27894504
15.

[Cancer cell plasticity and metastatic dissemination].

Moyret-Lalle C, Pommier R, Bouard C, Nouri E, Richard G, Puisieux A.

Med Sci (Paris). 2016 8-9;32(8-9):725-31. doi: 10.1051/medsci/20163208020. Epub 2016 Sep 12. Review. French.

16.

ZEB1-mediated melanoma cell plasticity enhances resistance to MAPK inhibitors.

Richard G, Dalle S, Monet MA, Ligier M, Boespflug A, Pommier RM, de la Fouchardière A, Perier-Muzet M, Depaepe L, Barnault R, Tondeur G, Ansieau S, Thomas E, Bertolotto C, Ballotti R, Mourah S, Battistella M, Lebbé C, Thomas L, Puisieux A, Caramel J.

EMBO Mol Med. 2016 Oct 4;8(10):1143-1161. doi: 10.15252/emmm.201505971. Print 2016 Oct.

17.

Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma.

Chicard M, Boyault S, Colmet Daage L, Richer W, Gentien D, Pierron G, Lapouble E, Bellini A, Clement N, Iacono I, Bréjon S, Carrere M, Reyes C, Hocking T, Bernard V, Peuchmaur M, Corradini N, Faure-Conter C, Coze C, Plantaz D, Defachelles AS, Thebaud E, Gambart M, Millot F, Valteau-Couanet D, Michon J, Puisieux A, Delattre O, Combaret V, Schleiermacher G.

Clin Cancer Res. 2016 Nov 15;22(22):5564-5573. doi: 10.1158/1078-0432.CCR-16-0500. Epub 2016 Jul 20.

18.

[The enigma of the biological interpretation of the linear-quadratic model finally resolved? A summary for non-mathematicians].

Bodgi L, Canet A, Granzotto A, Britel M, Puisieux A, Bourguignon M, Foray N.

Cancer Radiother. 2016 Jun;20(4):314-21. doi: 10.1016/j.canrad.2016.02.014. Epub 2016 Jun 21. French.

PMID:
27342947
19.

The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells.

Jacqueroud L, Bouard C, Richard G, Payen L, Devouassoux-Shisheboran M, Spicer DB, Caramel J, Collin G, Puisieux A, Tissier A, Ansieau S.

Neoplasia. 2016 May;18(5):317-327. doi: 10.1016/j.neo.2016.03.007.

20.

Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences.

Bouard C, Terreux R, Honorat M, Manship B, Ansieau S, Vigneron AM, Puisieux A, Payen L.

Nucleic Acids Res. 2016 Jun 20;44(11):5470-89. doi: 10.1093/nar/gkw334. Epub 2016 May 5.

21.

[Repeated radiation dose effect and DNA repair: Importance of the individual factor and the time interval between the doses].

Viau M, Perez AF, Bodgi L, Devic C, Granzotto A, Ferlazzo ML, Bourguignon M, Puisieux A, Lacornerie T, Lartigau É, Lagrange JL, Foray N.

Cancer Radiother. 2016 May;20(3):217-25. doi: 10.1016/j.canrad.2015.05.035. Epub 2016 Mar 22. Review. French.

PMID:
27020715
22.

Influence of Nucleoshuttling of the ATM Protein in the Healthy Tissues Response to Radiation Therapy: Toward a Molecular Classification of Human Radiosensitivity.

COPERNIC project investigators, Granzotto A, Benadjaoud MA, Vogin G, Devic C, Ferlazzo ML, Bodgi L, Pereira S, Sonzogni L, Forcheron F, Viau M, Etaix A, Malek K, Mengue-Bindjeme L, Escoffier C, Rouvet I, Zabot MT, Joubert A, Vincent A, Dalla Venezia N, Bourguignon M, Canat EP, d'Hombres A, Thébaud E, Orbach D, Stoppa-Lyonnet D, Radji A, Doré E, Pointreau Y, Bourgier C, Leblond P, Defachelles AS, Lervat C, Guey S, Feuvret L, Gilsoul F, Berger C, Moncharmont C, de Laroche G, Moreau-Claeys MV, Chavaudra N, Combemale P, Biston MC, Malet C, Martel-Lafay I, Laude C, Hau-Desbat NH, Ziouéche A, Tanguy R, Sunyach MP, Racadot S, Pommier P, Claude L, Baleydier F, Fleury B, de Crevoisier R, Simon JM, Verrelle P, Peiffert D, Belkacemi Y, Bourhis J, Lartigau E, Carrie C, De Vathaire F, Eschwege F, Puisieux A, Lagrange JL, Balosso J, Foray N.

Int J Radiat Oncol Biol Phys. 2016 Mar 1;94(3):450-60. doi: 10.1016/j.ijrobp.2015.11.013. Epub 2015 Nov 14.

PMID:
26867874
23.

TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability.

Pommier RM, Gout J, Vincent DF, Alcaraz LB, Chuvin N, Arfi V, Martel S, Kaniewski B, Devailly G, Fourel G, Bernard P, Moyret-Lalle C, Ansieau S, Puisieux A, Valcourt U, Sentis S, Bartholin L.

Cancer Res. 2015 Oct 15;75(20):4335-50. doi: 10.1158/0008-5472.CAN-14-3426. Epub 2015 Aug 17.

24.

[Quinze questions importantes à se poser en oncologie en 2015].

Blay JY, Tredan O, Ray-Coquard I, Rivoire M, Mehlen P, Puisieux A, Bachelot T.

Bull Cancer. 2015 Jun;102(6 Suppl 1):S22-6. doi: 10.1016/S0007-4551(15)31214-5. Review. French.

PMID:
26118872
25.

Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells.

Devailly G, Grandin M, Perriaud L, Mathot P, Delcros JG, Bidet Y, Morel AP, Bignon JY, Puisieux A, Mehlen P, Dante R.

Nucleic Acids Res. 2015 Jul 13;43(12):5838-54. doi: 10.1093/nar/gkv508. Epub 2015 May 24.

26.

Les Entretiens Jacques Cartier Symposium 4--targeted cancer therapies: stakes and prospects for patients.

Cox DG, Puisieux A.

Mutagenesis. 2015 Mar;30(2):167-8. doi: 10.1093/mutage/geu085. No abstract available.

PMID:
25688109
27.

Copper isotope effect in serum of cancer patients. A pilot study.

Télouk P, Puisieux A, Fujii T, Balter V, Bondanese VP, Morel AP, Clapisson G, Lamboux A, Albarede F.

Metallomics. 2015 Feb;7(2):299-308. doi: 10.1039/c4mt00269e.

PMID:
25532497
28.

TWIST1 is a direct transcriptional target of MYCN and MYC in neuroblastoma.

Selmi A, de Saint-Jean M, Jallas AC, Garin E, Hogarty MD, Bénard J, Puisieux A, Marabelle A, Valsesia-Wittmann S.

Cancer Lett. 2015 Feb 1;357(1):412-418. doi: 10.1016/j.canlet.2014.11.056. Epub 2014 Dec 1.

PMID:
25475555
29.

MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts.

Payen L, Honorat M, Guitton J, Gauthier C, Bouard C, Lecerf-Schmidt F, Peres B, Terreux R, Gervot H, Rioufol C, Boumendjel A, Puisieux A, Di Pietro A.

Oncotarget. 2014 Dec 15;5(23):11957-70.

30.

ABCG2, a novel antigen to sort luminal progenitors of BRCA1- breast cancer cells.

Leccia F, Del Vecchio L, Mariotti E, Di Noto R, Morel AP, Puisieux A, Salvatore F, Ansieau S.

Mol Cancer. 2014 Sep 12;13:213. doi: 10.1186/1476-4598-13-213.

31.

Epithelial-mesenchymal transition transcription factors and miRNAs: "Plastic surgeons" of breast cancer.

Moyret-Lalle C, Ruiz E, Puisieux A.

World J Clin Oncol. 2014 Aug 10;5(3):311-22. doi: 10.5306/wjco.v5.i3.311. Review.

32.

Oncogenic roles of EMT-inducing transcription factors.

Puisieux A, Brabletz T, Caramel J.

Nat Cell Biol. 2014 Jun;16(6):488-94. doi: 10.1038/ncb2976. Review.

PMID:
24875735
33.

The emerging role of Twist proteins in hematopoietic cells and hematological malignancies.

Merindol N, Riquet A, Szablewski V, Eliaou JF, Puisieux A, Bonnefoy N.

Blood Cancer J. 2014 Apr 25;4:e206. doi: 10.1038/bcj.2014.22. Review. Erratum in: Blood Cancer J. 2014 Oct;4:e254.

34.

Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells.

Gras B, Jacqueroud L, Wierinckx A, Lamblot C, Fauvet F, Lachuer J, Puisieux A, Ansieau S.

PLoS One. 2014 Mar 17;9(3):e92254. doi: 10.1371/journal.pone.0092254. eCollection 2014.

35.

TWIST1 expression in breast cancer cells facilitates bone metastasis formation.

Croset M, Goehrig D, Frackowiak A, Bonnelye E, Ansieau S, Puisieux A, Clézardin P.

J Bone Miner Res. 2014 Aug;29(8):1886-99. doi: 10.1002/jbmr.2215.

36.

A switch in the expression of embryonic EMT-inducers drives the development of malignant melanoma.

Caramel J, Papadogeorgakis E, Hill L, Browne GJ, Richard G, Wierinckx A, Saldanha G, Osborne J, Hutchinson P, Tse G, Lachuer J, Puisieux A, Pringle JH, Ansieau S, Tulchinsky E.

Cancer Cell. 2013 Oct 14;24(4):466-80. doi: 10.1016/j.ccr.2013.08.018. Epub 2013 Sep 26.

37.

p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer.

Marcel V, Ghayad SE, Belin S, Therizols G, Morel AP, Solano-Gonzàlez E, Vendrell JA, Hacot S, Mertani HC, Albaret MA, Bourdon JC, Jordan L, Thompson A, Tafer Y, Cong R, Bouvet P, Saurin JC, Catez F, Prats AC, Puisieux A, Diaz JJ.

Cancer Cell. 2013 Sep 9;24(3):318-30. doi: 10.1016/j.ccr.2013.08.013.

38.

PLA2R1 mediates tumor suppression by activating JAK2.

Vindrieux D, Augert A, Girard CA, Gitenay D, Lallet-Daher H, Wiel C, Le Calvé B, Gras B, Ferrand M, Verbeke S, de Launoit Y, Leroy X, Puisieux A, Aubert S, Perrais M, Gelb M, Simonnet H, Lambeau G, Bernard D.

Cancer Res. 2013 Oct 15;73(20):6334-45. doi: 10.1158/0008-5472.CAN-13-0318. Epub 2013 Sep 5.

39.

PLA2R1 kills cancer cells by inducing mitochondrial stress.

Augert A, Vindrieux D, Girard CA, Le Calvé B, Gras B, Ferrand M, Bouchet BP, Puisieux A, de Launoit Y, Simonnet H, Lambeau G, Bernard D.

Free Radic Biol Med. 2013 Dec;65:969-77. doi: 10.1016/j.freeradbiomed.2013.08.177. Epub 2013 Aug 29.

PMID:
23994771
40.

Modulation of oxidative stress by twist oncoproteins.

Floc'h N, Kolodziejski J, Akkari L, Simonin Y, Ansieau S, Puisieux A, Hibner U, Lassus P.

PLoS One. 2013 Aug 13;8(8):e72490. doi: 10.1371/journal.pone.0072490. eCollection 2013.

41.

Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes.

Bouard C, Terreux R, Hope J, Chemelle JA, Puisieux A, Ansieau S, Payen L.

J Biomol Struct Dyn. 2014;32(2):226-41. doi: 10.1080/07391102.2012.762722. Epub 2013 Mar 25.

42.

[Epithelial-mesenchymal transition and liver fibrosis : guilty or not guilty?].

Puisieux A.

Bull Acad Natl Med. 2012 Jan;196(1):105-13. French.

PMID:
23259338
43.

Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition.

Hesling C, Lopez J, Fattet L, Gonzalo P, Treilleux I, Blanchard D, Losson R, Goffin V, Pigat N, Puisieux A, Mikaelian I, Gillet G, Rimokh R.

Development. 2013 Jan 1;140(1):167-75. doi: 10.1242/dev.085068. Epub 2012 Nov 15.

44.

Impaired IFN-α production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression.

Sisirak V, Faget J, Gobert M, Goutagny N, Vey N, Treilleux I, Renaudineau S, Poyet G, Labidi-Galy SI, Goddard-Leon S, Durand I, Le Mercier I, Bajard A, Bachelot T, Puisieux A, Puisieux I, Blay JY, Ménétrier-Caux C, Caux C, Bendriss-Vermare N.

Cancer Res. 2012 Oct 15;72(20):5188-97. doi: 10.1158/0008-5472.CAN-11-3468. Epub 2012 Jul 25.

45.

EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.

Morel AP, Hinkal GW, Thomas C, Fauvet F, Courtois-Cox S, Wierinckx A, Devouassoux-Shisheboran M, Treilleux I, Tissier A, Gras B, Pourchet J, Puisieux I, Browne GJ, Spicer DB, Lachuer J, Ansieau S, Puisieux A.

PLoS Genet. 2012;8(5):e1002723. doi: 10.1371/journal.pgen.1002723. Epub 2012 May 24.

46.

TWIST1 a new determinant of epithelial to mesenchymal transition in EGFR mutated lung adenocarcinoma.

Pallier K, Cessot A, Côté JF, Just PA, Cazes A, Fabre E, Danel C, Riquet M, Devouassoux-Shisheboran M, Ansieau S, Puisieux A, Laurent-Puig P, Blons H.

PLoS One. 2012;7(1):e29954. doi: 10.1371/journal.pone.0029954. Epub 2012 Jan 17.

47.

Failsafe program escape and EMT: a deleterious partnership.

Ansieau S, Courtois-Cox S, Morel AP, Puisieux A.

Semin Cancer Biol. 2011 Dec;21(6):392-6. doi: 10.1016/j.semcancer.2011.09.014. Epub 2011 Oct 5. Review.

PMID:
21986518
48.

CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues.

Sisirak V, Vey N, Vanbervliet B, Duhen T, Puisieux I, Homey B, Bowman EP, Trinchieri G, Dubois B, Kaiserlian D, Lira SA, Puisieux A, Blay JY, Caux C, Bendriss-Vermare N.

Blood. 2011 Nov 10;118(19):5130-40. doi: 10.1182/blood-2010-07-295626. Epub 2011 Sep 21.

49.

Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer.

Coissieux MM, Tomsic J, Castets M, Hampel H, Tuupanen S, Andrieu N, Comeras I, Drouet Y, Lasset C, Liyanarachchi S, Mazelin L, Puisieux A, Saurin JC, Scoazec JY, Wang Q, Aaltonen L, Tanner SM, de la Chapelle A, Bernet A, Mehlen P.

Gastroenterology. 2011 Dec;141(6):2039-46. doi: 10.1053/j.gastro.2011.08.041. Epub 2011 Sep 3.

50.

βIII-Tubulin is required for interphase microtubule dynamics in untransformed human mammary epithelial cells.

Bouchet BP, Puisieux A, Galmarini CM.

Eur J Cell Biol. 2011 Oct;90(10):872-8. doi: 10.1016/j.ejcb.2011.05.005. Epub 2011 Aug 4.

PMID:
21820201

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