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Items: 1 to 50 of 233

1.

Nonadherence and unsuppressed viral load across adolescence among US youth with perinatally acquired HIV.

Kacanek D, Huo Y, Malee K, Mellins CA, Smith R, Garvie PA, Tassiopoulos K, Lee S, Berman C, Paul M, Puga A, Allison S; Pediatric HIV/AIDS Cohort Study.

AIDS. 2019 Jul 3. doi: 10.1097/QAD.0000000000002301. [Epub ahead of print]

PMID:
31274538
2.

Highlight Article: Chromium exposure disrupts chromatin architecture upsetting the mechanisms that regulate transcription.

Zablon HA, VonHandorf A, Puga A.

Exp Biol Med (Maywood). 2019 Jun;244(9):752-757. doi: 10.1177/1535370219839953. Epub 2019 Apr 1.

PMID:
30935235
3.

Effects of Drugs and Excipients on Hydration Status.

Puga AM, Lopez-Oliva S, Trives C, Partearroyo T, Varela-Moreiras G.

Nutrients. 2019 Mar 20;11(3). pii: E669. doi: 10.3390/nu11030669. Review.

4.

Interplay between Nutrition and Hearing Loss: State of Art.

Puga AM, Pajares MA, Varela-Moreiras G, Partearroyo T.

Nutrients. 2018 Dec 24;11(1). pii: E35. doi: 10.3390/nu11010035. Review.

5.

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment.

Parrini M, Meissl K, Ola MJ, Lederer T, Puga A, Wienerroither S, Kovarik P, Decker T, Müller M, Strobl B.

Front Immunol. 2018 Dec 6;9:2879. doi: 10.3389/fimmu.2018.02879. eCollection 2018.

6.

Prenatal exposure to PCBs in Cyp1a2 knock-out mice interferes with F1 fertility, impairs long-term potentiation, reduces acoustic startle and impairs conditioned freezing contextual memory with minimal transgenerational effects.

Hufgard JR, Sprowles JLN, Pitzer EM, Koch SE, Jiang M, Wang Q, Zhang X, Biesiada J, Rubinstein J, Puga A, Williams MT, Vorhees CV.

J Appl Toxicol. 2019 Apr;39(4):603-621. doi: 10.1002/jat.3751. Epub 2018 Dec 18.

PMID:
30561030
7.

Old Receptor, New Tricks-The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report from the 4th AHR Meeting, 29⁻31 August 2018 in Paris, France.

Esser C, Lawrence BP, Sherr DH, Perdew GH, Puga A, Barouki R, Coumoul X.

Int J Mol Sci. 2018 Nov 15;19(11). pii: E3603. doi: 10.3390/ijms19113603.

8.

A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection.

Andrade EB, Magalhães A, Puga A, Costa M, Bravo J, Portugal CC, Ribeiro A, Correia-Neves M, Faustino A, Firon A, Trieu-Cuot P, Summavielle T, Ferreira P.

Nat Commun. 2018 Aug 7;9(1):3138. doi: 10.1038/s41467-018-05492-y.

9.

Carbon stability and mitigation of fertilizer induced N2O emissions in soil amended with biochar.

Grutzmacher P, Puga AP, Bibar MPS, Coscione AR, Packer AP, de Andrade CA.

Sci Total Environ. 2018 Jun 1;625:1459-1466. doi: 10.1016/j.scitotenv.2017.12.196. Epub 2018 Jan 12.

PMID:
29996442
10.

Quantitative Systems Pharmacology Modeling of Acid Sphingomyelinase Deficiency and the Enzyme Replacement Therapy Olipudase Alfa Is an Innovative Tool for Linking Pathophysiology and Pharmacology.

Kaddi CD, Niesner B, Baek R, Jasper P, Pappas J, Tolsma J, Li J, van Rijn Z, Tao M, Ortemann-Renon C, Easton R, Tan S, Puga AC, Schuchman EH, Barrett JS, Azer K.

CPT Pharmacometrics Syst Pharmacol. 2018 Jul;7(7):442-452. doi: 10.1002/psp4.12304. Epub 2018 Jun 19.

11.

Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes.

VonHandorf A, Sánchez-Martín FJ, Biesiada J, Zhang H, Zhang X, Medvedovic M, Puga A.

Epigenetics. 2018;13(4):363-375. doi: 10.1080/15592294.2018.1454243. Epub 2018 May 3.

12.

Epigenetics as a mechanism linking developmental exposures to long-term toxicity.

Barouki R, Melén E, Herceg Z, Beckers J, Chen J, Karagas M, Puga A, Xia Y, Chadwick L, Yan W, Audouze K, Slama R, Heindel J, Grandjean P, Kawamoto T, Nohara K.

Environ Int. 2018 May;114:77-86. doi: 10.1016/j.envint.2018.02.014. Epub 2018 Feb 27. Review.

13.

Olipudase alfa for treatment of acid sphingomyelinase deficiency (ASMD): safety and efficacy in adults treated for 30 months.

Wasserstein MP, Diaz GA, Lachmann RH, Jouvin MH, Nandy I, Ji AJ, Puga AC.

J Inherit Metab Dis. 2018 Sep;41(5):829-838. doi: 10.1007/s10545-017-0123-6. Epub 2018 Jan 5.

14.

Aryl Hydrocarbon Receptor Ablation in Cardiomyocytes Protects Male Mice From Heart Dysfunction Induced by NKX2.5 Haploinsufficiency.

Wang Q, Fan Y, Kurita H, Jiang M, Koch S, Rao MB, Rubinstein J, Puga A.

Toxicol Sci. 2017 Nov 1;160(1):74-82. doi: 10.1093/toxsci/kfx164.

15.

Does the Aryl Hydrocarbon Receptor Regulate Pluripotency?

Ko CI, Puga A.

Curr Opin Toxicol. 2017 Feb;2:1-7. doi: 10.1016/j.cotox.2017.01.004. Epub 2017 Jan 21.

16.

Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer.

Khanal T, Choi K, Leung YK, Wang J, Kim D, Janakiram V, Cho SG, Puga A, Ho SM, Kim K.

Sci Rep. 2017 Sep 6;7(1):10662. doi: 10.1038/s41598-017-11106-2.

17.

Hydration status, drug interactions, and determinants in a Spanish elderly population: a pilot study.

Puga AM, Partearroyo T, Varela-Moreiras G.

J Physiol Biochem. 2018 Feb;74(1):139-151. doi: 10.1007/s13105-017-0585-x. Epub 2017 Aug 10.

PMID:
28799126
18.

Long-term pulmonary complications in perinatally HIV-infected youth.

Shearer WT, Jacobson DL, Yu W, Siberry GK, Purswani M, Siminski S, Butler L, Leister E, Scott G, Van Dyke RB, Yogev R, Paul ME, Puga A, Colin AA, Kattan M; Pediatric HIV/AIDS Cohort Study.

J Allergy Clin Immunol. 2017 Oct;140(4):1101-1111.e7. doi: 10.1016/j.jaci.2017.01.031. Epub 2017 Mar 6.

19.

Chronic Type A Aortic Dissection and Giant Aortic Root Aneurysm After Aortic Valve Replacement.

Puga AE, Rodríguez SC, Pañero BM, Moreira BC, López Almodóvar LF.

Aorta (Stamford). 2016 Jun 1;4(3):108-110. doi: 10.12945/j.aorta.2016.15.028. eCollection 2016 Jun.

21.

Repression of the Aryl Hydrocarbon Receptor Is Required to Maintain Mitotic Progression and Prevent Loss of Pluripotency of Embryonic Stem Cells.

Ko CI, Fan Y, de Gannes M, Wang Q, Xia Y, Puga A.

Stem Cells. 2016 Dec;34(12):2825-2839. doi: 10.1002/stem.2456. Epub 2016 Jul 15.

22.

Clearance of Hepatic Sphingomyelin by Olipudase Alfa Is Associated With Improvement in Lipid Profiles in Acid Sphingomyelinase Deficiency.

Thurberg BL, Wasserstein MP, Jones SA, Schiano TD, Cox GF, Puga AC.

Am J Surg Pathol. 2016 Sep;40(9):1232-42. doi: 10.1097/PAS.0000000000000659.

23.

Following young people with perinatal HIV infection from adolescence into adulthood: the protocol for PHACS AMP Up, a prospective cohort study.

Tassiopoulos K, Patel K, Alperen J, Kacanek D, Ellis A, Berman C, Allison SM, Hazra R, Barr E, Cantos K, Siminski S, Massagli M, Bauermeister J, Siddiqui DQ, Puga A, Van Dyke R, Seage GR 3rd; Pediatric HIV/AIDS Cohort Study.

BMJ Open. 2016 Jun 9;6(6):e011396. doi: 10.1136/bmjopen-2016-011396.

24.

Ah receptor expression in cardiomyocytes protects adult female mice from heart dysfunction induced by TCDD exposure.

Kurita H, Carreira VS, Fan Y, Jiang M, Naticchioni M, Koch S, Rubinstein J, Puga A.

Toxicology. 2016 Apr 29;355-356:9-20. doi: 10.1016/j.tox.2016.05.006. Epub 2016 May 6.

PMID:
27163630
25.

Exposure to Violence and Virologic and Immunological Outcomes Among Youth With Perinatal HIV in the Pediatric HIV/AIDS Cohort Study.

Kacanek D, Malee K, Mellins CA, Tassiopoulos K, Smith R, Grant M, Lee S, Siddiqui DQ, Puga A.

J Adolesc Health. 2016 Jul;59(1):30-7. doi: 10.1016/j.jadohealth.2016.03.004. Epub 2016 Apr 15.

26.

Antiretroviral Drug Resistance Among Children and Youth in the United States With Perinatal HIV.

Van Dyke RB, Patel K, Kagan RM, Karalius B, Traite S, Meyer WA 3rd, Tassiopoulos KK, Seage GR 3rd, Seybolt LM, Burchett S, Hazra R; Pediatric HIV/AIDS Cohort Study (PHACS), Lurie RH, Yogev R, Sanders MA, Malee K, Hunter S, Shearer W, Paul M, Cooper N, Harris L, Purswani M, Baig M, Cintron A, Puga A, Navarro S, Garvie P, Blood J, Burchett S, Karthas N, Kammerer B, Wiznia A, Burey M, Nozyce M, Dieudonne A, Bettica L, Adubato S, Chen J, Bulkley MG, Ivey L, Grant M, Knapp K, Allison K, Wilkins M, Acevedo-Flores M, Rios H, Olivera V, Silio M, Jones M, Sirois P, Spector S, Norris K, Nichols S, McFarland E, Katai A, Dunn J, Paul S, Scott G, Bryan P, Willen E.

Clin Infect Dis. 2016 Jul 1;63(1):133-137. doi: 10.1093/cid/ciw213. Epub 2016 Apr 7.

27.

The DESCARTES-Nantes survey of kidney transplant recipients displaying clinical operational tolerance identifies 35 new tolerant patients and 34 almost tolerant patients.

Massart A, Pallier A, Pascual J, Viklicky O, Budde K, Spasovski G, Klinger M, Sever MS, Sørensen SS, Hadaya K, Oberbauer R, Dudley C, De Fijter JW, Yussim A, Hazzan M, Wekerle T, Berglund D, De Biase C, Pérez-Sáez MJ, Mühlfeld A, Orlando G, Clemente K, Lai Q, Pisani F, Kandus A, Baas M, Bemelman F, Ponikvar JB, Mazouz H, Stratta P, Subra JF, Villemain F, Hoitsma A, Braun L, Cantarell MC, Colak H, Courtney A, Frasca GM, Howse M, Naesens M, Reischig T, Serón D, Seyahi N, Tugmen C, Alonso Hernandez A, Beňa L, Biancone L, Cuna V, Díaz-Corte C, Dufay A, Gaasbeek A, Garnier A, Gatault P, Gentil Govantes MA, Glowacki F, Gross O, Hurault de Ligny B, Huynh-Do U, Janbon B, Jiménez Del Cerro LA, Keller F, La Manna G, Lauzurica R, Le Monies De Sagazan H, Thaiss F, Legendre C, Martin S, Moal MC, Noël C, Pillebout E, Piredda GB, Puga AR, Sulowicz W, Tuglular S, Prokopova M, Chesneau M, Le Moine A, Guérif P, Soulillou JP, Abramowicz M, Giral M, Racapé J, Maggiore U, Brouard S, Abramowicz D.

Nephrol Dial Transplant. 2016 Jun;31(6):1002-13. doi: 10.1093/ndt/gfv437. Epub 2016 Jan 12.

PMID:
26763669
28.

Ah Receptor Activation by Dioxin Disrupts Activin, BMP, and WNT Signals During the Early Differentiation of Mouse Embryonic Stem Cells and Inhibits Cardiomyocyte Functions.

Wang Q, Kurita H, Carreira V, Ko CI, Fan Y, Zhang X, Biesiada J, Medvedovic M, Puga A.

Toxicol Sci. 2016 Feb;149(2):346-57. doi: 10.1093/toxsci/kfv246. Epub 2015 Nov 15.

29.

Covalent binding of quinones activates the Ah receptor in Hepa1c1c7 cells.

Abiko Y, Puga A, Kumagai Y.

J Toxicol Sci. 2015 Dec;40(6):873-86. doi: 10.2131/jts.40.873.

30.

Disruption of Ah Receptor Signaling during Mouse Development Leads to Abnormal Cardiac Structure and Function in the Adult.

Carreira VS, Fan Y, Kurita H, Wang Q, Ko CI, Naticchioni M, Jiang M, Koch S, Zhang X, Biesiada J, Medvedovic M, Xia Y, Rubinstein J, Puga A.

PLoS One. 2015 Nov 10;10(11):e0142440. doi: 10.1371/journal.pone.0142440. eCollection 2015.

31.

Additive manufacturing of scaffolds with dexamethasone controlled release for enhanced bone regeneration.

Costa PF, Puga AM, Díaz-Gomez L, Concheiro A, Busch DH, Alvarez-Lorenzo C.

Int J Pharm. 2015 Dec 30;496(2):541-50. doi: 10.1016/j.ijpharm.2015.10.055. Epub 2015 Oct 28.

PMID:
26520408
32.

Antiretroviral treatment initiation does not differentially alter neurocognitive functioning over time in youth with behaviorally acquired HIV.

Nichols SL, Bethel J, Kapogiannis BG, Li T, Woods SP, Patton ED, Ren W, Thornton SE, Major-Wilson HO, Puga AM, Sleasman JW, Rudy BJ, Wilson CM, Garvie PA; Adolescent Medicine Trials Network for HIV/AIDS Interventions.

J Neurovirol. 2016 Apr;22(2):218-30. doi: 10.1007/s13365-015-0389-0. Epub 2015 Oct 13.

33.

Prenatal and early postnatal lead exposure in mice: neuroimaging findings.

Lindquist DM, Beckwith T, Cecil KM, Sánchez-Martín FJ, Landero-Figueroa J, Puga A.

Quant Imaging Med Surg. 2015 Aug;5(4):511-8. doi: 10.3978/j.issn.2223-4292.2015.07.01.

34.

Prevalence and Persistence of Varicella Antibodies in Previously Immunized Children and Youth With Perinatal HIV-1 Infection.

Purswani MU, Karalius B, Yao TJ, Schmid DS, Burchett SK, Siberry GK, Patel K, Van Dyke RB, Yogev R; Pediatric HIV/AIDS Cohort Study (PHACS), Lurie RH, Yogev R, Sanders MA, Malee K, Hunter S, Shearer W, Paul M, Cooper N, Harris L, Purswani M, Baig M, Cintron A, Puga A, Navarro S, Garvie P, Blood J, Burchett S, Karthas N, Kammerer B, Wiznia A, Burey M, Nozyce M, Dieudonne A, Bettica L, Adubato S, Chen J, Bulkley MG, Ivey L, Grant M, Knapp K, Allison K, Wilkins M, Acevedo-Flores M, Rios H, Olivera V, Silio M, Jones M, Sirois P, Spector S, Norris K, Nichols S, McFarland E, Katai A, Dunn J, Paul S, Scott G, Bryan P, Willen E.

Clin Infect Dis. 2016 Jan 1;62(1):106-114. doi: 10.1093/cid/civ734. Epub 2015 Sep 18.

35.

Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives.

Grandjean P, Barouki R, Bellinger DC, Casteleyn L, Chadwick LH, Cordier S, Etzel RA, Gray KA, Ha EH, Junien C, Karagas M, Kawamoto T, Paige Lawrence B, Perera FP, Prins GS, Puga A, Rosenfeld CS, Sherr DH, Sly PD, Suk W, Sun Q, Toppari J, van den Hazel P, Walker CL, Heindel JJ.

Endocrinology. 2015 Oct;156(10):3408-15. doi: 10.1210/EN.2015-1350. Epub 2015 Aug 4.

36.

Cadmium, lead, and zinc mobility and plant uptake in a mine soil amended with sugarcane straw biochar.

Puga AP, Abreu CA, Melo LC, Paz-Ferreiro J, Beesley L.

Environ Sci Pollut Res Int. 2015 Nov;22(22):17606-14. doi: 10.1007/s11356-015-4977-6. Epub 2015 Jul 7.

PMID:
26146374
37.

Ah Receptor Signaling Controls the Expression of Cardiac Development and Homeostasis Genes.

Carreira VS, Fan Y, Wang Q, Zhang X, Kurita H, Ko CI, Naticchioni M, Jiang M, Koch S, Medvedovic M, Xia Y, Rubinstein J, Puga A.

Toxicol Sci. 2015 Oct;147(2):425-35. doi: 10.1093/toxsci/kfv138. Epub 2015 Jul 2.

38.

Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood.

Li Y, Xie C, Murphy SK, Skaar D, Nye M, Vidal AC, Cecil KM, Dietrich KN, Puga A, Jirtle RL, Hoyo C.

Environ Health Perspect. 2016 May;124(5):666-73. doi: 10.1289/ehp.1408577. Epub 2015 Jun 26.

39.

Gene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid Morphogenesis.

Mongan M, Meng Q, Wang J, Kao WW, Puga A, Xia Y.

J Biol Chem. 2015 Aug 7;290(32):19770-9. doi: 10.1074/jbc.M115.665729. Epub 2015 Jun 24.

40.

Successful within-patient dose escalation of olipudase alfa in acid sphingomyelinase deficiency.

Wasserstein MP, Jones SA, Soran H, Diaz GA, Lippa N, Thurberg BL, Culm-Merdek K, Shamiyeh E, Inguilizian H, Cox GF, Puga AC.

Mol Genet Metab. 2015 Sep-Oct;116(1-2):88-97. doi: 10.1016/j.ymgme.2015.05.013. Epub 2015 May 30.

41.

Biochar application to a contaminated soil reduces the availability and plant uptake of zinc, lead and cadmium.

Puga AP, Abreu CA, Melo LCA, Beesley L.

J Environ Manage. 2015 Aug 15;159:86-93. doi: 10.1016/j.jenvman.2015.05.036. Epub 2015 Jun 2.

PMID:
26048395
42.

Long-term Coexposure to Hexavalent Chromium and B[a]P Causes Tissue-Specific Differential Biological Effects in Liver and Gastrointestinal Tract of Mice.

Sánchez-Martín FJ, Fan Y, Carreira V, Ovesen JL, Vonhandorf A, Xia Y, Puga A.

Toxicol Sci. 2015 Jul;146(1):52-64. doi: 10.1093/toxsci/kfv070. Epub 2015 Mar 29.

43.

Eliglustat compared with imiglucerase in patients with Gaucher's disease type 1 stabilised on enzyme replacement therapy: a phase 3, randomised, open-label, non-inferiority trial.

Cox TM, Drelichman G, Cravo R, Balwani M, Burrow TA, Martins AM, Lukina E, Rosenbloom B, Ross L, Angell J, Puga AC.

Lancet. 2015 Jun 13;385(9985):2355-62. doi: 10.1016/S0140-6736(14)61841-9. Epub 2015 Mar 26. Erratum in: Lancet. 2015 Jun 13;385(9985):2354.

PMID:
25819691
44.

Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.

Winans B, Nagari A, Chae M, Post CM, Ko CI, Puga A, Kraus WL, Lawrence BP.

J Immunol. 2015 May 1;194(9):4446-57. doi: 10.4049/jimmunol.1402044. Epub 2015 Mar 25.

45.

3-Methylpiperidinium ionic liquids.

Belhocine T, Forsyth SA, Gunaratne HQ, Nieuwenhuyzen M, Nockemann P, Puga AV, Seddon KR, Srinivasan G, Whiston K.

Phys Chem Chem Phys. 2015 Apr 28;17(16):10398-416. doi: 10.1039/c4cp05936k.

46.

Women's attachment as a predictor of pain during labour and post-delivery: a prospective observational study.

Costa Martins JM, da Silva CF, Pereira M, Martins H, Oliveira C, Puga A, Coelho R, Tavares J.

Acta Med Port. 2014 Nov-Dec;27(6):692-9. Epub 2014 Dec 30.

47.

Using litigation to defend women prosecuted for abortion in Mexico: challenging state laws and the implications of recent court judgments.

Paine J, Noriega RT, Puga AL.

Reprod Health Matters. 2014 Nov;22(44):61-9. doi: 10.1016/S0968-8080(14)44800-6.

48.

Osteogenic poly(ε-caprolactone)/poloxamine homogeneous blends prepared by supercritical foaming.

de Matos MB, Puga AM, Alvarez-Lorenzo C, Concheiro A, Braga ME, de Sousa HC.

Int J Pharm. 2015 Feb 1;479(1):11-22. doi: 10.1016/j.ijpharm.2014.12.041. Epub 2014 Dec 23.

PMID:
25541145
49.

Sex- and tissue-specific methylome changes in brains of mice perinatally exposed to lead.

Sánchez-Martín FJ, Lindquist DM, Landero-Figueroa J, Zhang X, Chen J, Cecil KM, Medvedovic M, Puga A.

Neurotoxicology. 2015 Jan;46:92-100. doi: 10.1016/j.neuro.2014.12.004. Epub 2014 Dec 18.

50.

Efficient production and separation of biodegradable surfactants from cellulose in 1-butyl-3-methylimidazolium chloride.

Puga AV, Corma A.

ChemSusChem. 2014 Dec;7(12):3362-73. doi: 10.1002/cssc.201402722. Epub 2014 Oct 10.

PMID:
25302776

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