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Items: 24

1.

Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression.

Sasse SK, Gruca M, Allen MA, Kadiyala V, Song T, Gally F, Gupta A, Pufall MA, Dowell RD, Gerber AN.

Genome Res. 2019 Nov;29(11):1753-1765. doi: 10.1101/gr.248187.119. Epub 2019 Sep 13.

PMID:
31519741
2.

Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia.

Poulard C, Kim HN, Fang M, Kruth K, Gagnieux C, Gerke DS, Bhojwani D, Kim YM, Kampmann M, Stallcup MR, Pufall MA.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3052-3061. doi: 10.1073/pnas.1816254116. Epub 2019 Feb 7.

3.

Increasing G9a automethylation sensitizes B acute lymphoblastic leukemia cells to glucocorticoid-induced death.

Poulard C, Baulu E, Lee BH, Pufall MA, Stallcup MR.

Cell Death Dis. 2018 Oct 10;9(10):1038. doi: 10.1038/s41419-018-1110-z.

4.

Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors.

Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, Sánchez-García I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, Müschen M.

Nature. 2018 Jun;558(7711):E5. doi: 10.1038/s41586-018-0164-5.

5.

SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site.

Zhang L, Martini GD, Rube HT, Kribelbauer JF, Rastogi C, FitzPatrick VD, Houtman JC, Bussemaker HJ, Pufall MA.

Genome Res. 2018 Jan;28(1):111-121. doi: 10.1101/gr.222844.117. Epub 2017 Dec 1.

6.

Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages.

Rollins DA, Kharlyngdoh JB, Coppo M, Tharmalingam B, Mimouna S, Guo Z, Sacta MA, Pufall MA, Fisher RP, Hu X, Chinenov Y, Rogatsky I.

Nat Commun. 2017 Nov 23;8(1):1739. doi: 10.1038/s41467-017-01569-2.

7.

Defining Native Enhancer Function.

Pufall MA.

Cell Syst. 2017 Oct 25;5(4):310-312. doi: 10.1016/j.cels.2017.10.008.

8.

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.

Kruth KA, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA.

Blood. 2017 Jun 1;129(22):3000-3008. doi: 10.1182/blood-2017-02-766204. Epub 2017 Apr 19.

9.

Metabolic gatekeeper function of B-lymphoid transcription factors.

Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, Sánchez-García I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, Müschen M.

Nature. 2017 Feb 23;542(7642):479-483. doi: 10.1038/nature21076. Epub 2017 Feb 13. Erratum in: Nature. 2018 Jun;558(7711):E5.

10.

Glucocorticoids and Cancer.

Pufall MA.

Adv Exp Med Biol. 2015;872:315-33. doi: 10.1007/978-1-4939-2895-8_14. Review.

11.

Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops.

Sasse SK, Zuo Z, Kadiyala V, Zhang L, Pufall MA, Jain MK, Phang TL, Stormo GD, Gerber AN.

J Biol Chem. 2015 Aug 7;290(32):19756-69. doi: 10.1074/jbc.M115.668558. Epub 2015 Jun 18.

12.

JUNB is a key transcriptional modulator of macrophage activation.

Fontana MF, Baccarella A, Pancholi N, Pufall MA, Herbert DR, Kim CC.

J Immunol. 2015 Jan 1;194(1):177-86. doi: 10.4049/jimmunol.1401595. Epub 2014 Dec 3.

13.

Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.

Bongers KS, Fox DK, Kunkel SD, Stebounova LV, Murry DJ, Pufall MA, Ebert SM, Dyle MC, Bullard SA, Dierdorff JM, Adams CM.

Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E144-58. doi: 10.1152/ajpendo.00472.2014. Epub 2014 Nov 18.

14.

A naturally occurring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms.

Thomas-Chollier M, Watson LC, Cooper SB, Pufall MA, Liu JS, Borzym K, Vingron M, Yamamoto KR, Meijsing SH.

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17826-31. doi: 10.1073/pnas.1316235110. Epub 2013 Oct 14.

15.

Mechanisms of eukaryotic transcription.

Pufall MA, Kaplan CD.

Genome Biol. 2013;14(9):311.

16.

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals.

Watson LC, Kuchenbecker KM, Schiller BJ, Gross JD, Pufall MA, Yamamoto KR.

Nat Struct Mol Biol. 2013 Jul;20(7):876-83. doi: 10.1038/nsmb.2595. Epub 2013 Jun 2.

17.

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles.

Serafimova IM, Pufall MA, Krishnan S, Duda K, Cohen MS, Maglathlin RL, McFarland JM, Miller RM, Frödin M, Taunton J.

Nat Chem Biol. 2012 Apr 1;8(5):471-6. doi: 10.1038/nchembio.925.

18.

DNA binding site sequence directs glucocorticoid receptor structure and activity.

Meijsing SH, Pufall MA, So AY, Bates DL, Chen L, Yamamoto KR.

Science. 2009 Apr 17;324(5925):407-10. doi: 10.1126/science.1164265.

19.

The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region.

Lee GM, Pufall MA, Meeker CA, Kang HS, Graves BJ, McIntosh LP.

J Mol Biol. 2008 Oct 17;382(4):1014-30. doi: 10.1016/j.jmb.2008.07.064. Epub 2008 Jul 29.

20.

Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region.

Pufall MA, Lee GM, Nelson ML, Kang HS, Velyvis A, Kay LE, McIntosh LP, Graves BJ.

Science. 2005 Jul 1;309(5731):142-5.

21.

The structural and dynamic basis of Ets-1 DNA binding autoinhibition.

Lee GM, Donaldson LW, Pufall MA, Kang HS, Pot I, Graves BJ, McIntosh LP.

J Biol Chem. 2005 Feb 25;280(8):7088-99. Epub 2004 Dec 9.

22.

Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships.

Garvie CW, Pufall MA, Graves BJ, Wolberger C.

J Biol Chem. 2002 Nov 22;277(47):45529-36. Epub 2002 Sep 6.

23.

Autoinhibitory domains: modular effectors of cellular regulation.

Pufall MA, Graves BJ.

Annu Rev Cell Dev Biol. 2002;18:421-62. Epub 2002 Apr 2. Review.

PMID:
12142282
24.

Ets-1 flips for new partner Pax-5.

Pufall MA, Graves BJ.

Structure. 2002 Jan;10(1):11-4. Review.

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