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Items: 44

1.

Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1.

Freemerman AJ, Zhao L, Pingili AK, Teng B, Cozzo AJ, Fuller AM, Johnson AR, Milner JJ, Lim MF, Galanko JA, Beck MA, Bear JE, Rotty JD, Bezavada L, Smallwood HS, Puchowicz MA, Liu J, Locasale JW, Lee DP, Bennett BJ, Abel ED, Rathmell JC, Makowski L.

J Immunol. 2019 Feb 15;202(4):1265-1286. doi: 10.4049/jimmunol.1800002. Epub 2019 Jan 18.

2.

Disruption of brain-derived neurotrophic factor production from individual promoters generates distinct body composition phenotypes in mice.

McAllan L, Maynard KR, Kardian AS, Stayton AS, Fox SL, Stephenson EJ, Kinney CE, Alshibli NK, Gomes CK, Pierre JF, Puchowicz MA, Bridges D, Martinowich K, Han JC.

Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1168-E1184. doi: 10.1152/ajpendo.00205.2018. Epub 2018 Sep 25.

PMID:
30253111
3.

Post-resuscitation Arterial Blood Pressure on Survival and Change of Capillary Density Following Cardiac Arrest and Resuscitation in Rats.

Xu K, Puchowicz MA, LaManna JC.

Adv Exp Med Biol. 2018;1072:77-82. doi: 10.1007/978-3-319-91287-5_13.

PMID:
30178327
4.

Macrophages with a deletion of the phosphoenolpyruvate carboxykinase 1 (Pck1) gene have a more proinflammatory phenotype.

Ko CW, Counihan D, Wu J, Hatzoglou M, Puchowicz MA, Croniger CM.

J Biol Chem. 2018 Mar 2;293(9):3399-3409. doi: 10.1074/jbc.M117.819136. Epub 2018 Jan 9.

5.

Diet-Induced Ketosis Protects Against Focal Cerebral Ischemia in Mouse.

Xu K, Ye L, Sharma K, Jin Y, Harrison MM, Caldwell T, Berthiaume JM, Luo Y, LaManna JC, Puchowicz MA.

Adv Exp Med Biol. 2017;977:205-213. doi: 10.1007/978-3-319-55231-6_28.

PMID:
28685447
7.

Protective Effect of Dl-3-n-Butylphthalide on Recovery from Cardiac Arrest and Resuscitation in Rats.

Zhang L, Puchowicz MA, LaManna JC, Xu K.

Adv Exp Med Biol. 2016;923:31-36. doi: 10.1007/978-3-319-38810-6_4.

PMID:
27526121
8.

Aging Effect on Post-recovery Hypofusion and Mortality Following Cardiac Arrest and Resuscitation in Rats.

Xu K, Puchowicz MA, LaManna JC.

Adv Exp Med Biol. 2016;876:265-270. doi: 10.1007/978-1-4939-3023-4_33.

PMID:
26782221
9.

Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.

Frederick DW, Davis JG, Dávila A Jr, Agarwal B, Michan S, Puchowicz MA, Nakamaru-Ogiso E, Baur JA.

J Biol Chem. 2015 Jan 16;290(3):1546-58. doi: 10.1074/jbc.M114.579565. Epub 2014 Nov 19.

10.

Decreased carbon shunting from glucose toward oxidative metabolism in diet-induced ketotic rat brain.

Zhang Y, Zhang S, Marin-Valencia I, Puchowicz MA.

J Neurochem. 2015 Feb;132(3):301-12. doi: 10.1111/jnc.12965. Epub 2014 Nov 10.

11.

Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet.

Jin Z, Berthiaume JM, Li Q, Henry F, Huang Z, Sadhukhan S, Gao P, Tochtrop GP, Puchowicz MA, Zhang GF.

J Biol Chem. 2014 Nov 14;289(46):32327-38. doi: 10.1074/jbc.M114.602458. Epub 2014 Oct 1.

12.

Synergistic simvastatin and metformin combination chemotherapy for osseous metastatic castration-resistant prostate cancer.

Babcook MA, Shukla S, Fu P, Vazquez EJ, Puchowicz MA, Molter JP, Oak CZ, MacLennan GT, Flask CA, Lindner DJ, Parker Y, Daneshgari F, Gupta S.

Mol Cancer Ther. 2014 Oct;13(10):2288-302. doi: 10.1158/1535-7163.MCT-14-0451. Epub 2014 Aug 13.

13.

Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis.

Khan S, Abu Jawdeh BG, Goel M, Schilling WP, Parker MD, Puchowicz MA, Yadav SP, Harris RC, El-Meanawy A, Hoshi M, Shinlapawittayatorn K, Deschênes I, Ficker E, Schelling JR.

J Clin Invest. 2014 Mar;124(3):1057-68. doi: 10.1172/JCI71863. Epub 2014 Feb 17.

14.

Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver.

Ruiz R, Jideonwo V, Ahn M, Surendran S, Tagliabracci VS, Hou Y, Gamble A, Kerner J, Irimia-Dominguez JM, Puchowicz MA, DePaoli-Roach A, Hoppel C, Roach P, Morral N.

J Biol Chem. 2014 Feb 28;289(9):5510-7. doi: 10.1074/jbc.M113.541110. Epub 2014 Jan 7.

15.

Ketosis proportionately spares glucose utilization in brain.

Zhang Y, Kuang Y, Xu K, Harris D, Lee Z, LaManna J, Puchowicz MA.

J Cereb Blood Flow Metab. 2013 Aug;33(8):1307-11. doi: 10.1038/jcbfm.2013.87. Epub 2013 Jun 5.

16.

Targeting pyruvate carboxylase reduces gluconeogenesis and adiposity and improves insulin resistance.

Kumashiro N, Beddow SA, Vatner DF, Majumdar SK, Cantley JL, Guebre-Egziabher F, Fat I, Guigni B, Jurczak MJ, Birkenfeld AL, Kahn M, Perler BK, Puchowicz MA, Manchem VP, Bhanot S, Still CD, Gerhard GS, Petersen KF, Cline GW, Shulman GI, Samuel VT.

Diabetes. 2013 Jul;62(7):2183-94. doi: 10.2337/db12-1311. Epub 2013 Feb 19.

17.

Metabolomics and mass isotopomer analysis as a strategy for pathway discovery: pyrrolyl and cyclopentenyl derivatives of the pro-drug of abuse, levulinate.

Harris SR, Zhang GF, Sadhukhan S, Wang H, Shi C, Puchowicz MA, Anderson VE, Salomon RG, Tochtrop GP, Brunengraber H.

Chem Res Toxicol. 2013 Feb 18;26(2):213-20. doi: 10.1021/tx3003643. Epub 2012 Dec 6.

18.

Contribution of brain glucose and ketone bodies to oxidative metabolism.

Zhang Y, Kuang Y, LaManna JC, Puchowicz MA.

Adv Exp Med Biol. 2013;765:365-370. doi: 10.1007/978-1-4614-4989-8_51.

PMID:
22879057
19.

Neuroprotective properties of ketone bodies.

Xu K, Lamanna JC, Puchowicz MA.

Adv Exp Med Biol. 2012;737:97-102. doi: 10.1007/978-1-4614-1566-4_15. No abstract available.

PMID:
22259088
20.

Dietary regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver.

Li Q, Tomcik K, Zhang S, Puchowicz MA, Zhang GF.

Free Radic Biol Med. 2012 Mar 15;52(6):1043-53. doi: 10.1016/j.freeradbiomed.2011.12.022. Epub 2012 Jan 4.

21.

Regional brain blood flow in mouse: quantitative measurement using a single-pass radio-tracer method and a mathematical algorithm.

Xu K, Radhakrishnan K, Serhal A, Allen F, Lamanna JC, Puchowicz MA.

Adv Exp Med Biol. 2011;701:255-60. doi: 10.1007/978-1-4419-7756-4_34.

PMID:
21445795
22.

Analysis of the citric acid cycle intermediates using gas chromatography-mass spectrometry.

Kombu RS, Brunengraber H, Puchowicz MA.

Methods Mol Biol. 2011;708:147-57. doi: 10.1007/978-1-61737-985-7_8.

PMID:
21207288
23.

Decreased brainstem function following cardiac arrest and resuscitation in aged rat.

Xu K, Puchowicz MA, Sun X, LaManna JC.

Brain Res. 2010 Apr 30;1328:181-9. doi: 10.1016/j.brainres.2010.02.080. Epub 2010 Mar 6.

24.

Diet-induced ketosis improves cognitive performance in aged rats.

Xu K, Sun X, Eroku BO, Tsipis CP, Puchowicz MA, LaManna JC.

Adv Exp Med Biol. 2010;662:71-5. doi: 10.1007/978-1-4419-1241-1_9.

25.

Neuroprotection in diet-induced ketotic rat brain after focal ischemia.

Puchowicz MA, Zechel JL, Valerio J, Emancipator DS, Xu K, Pundik S, LaManna JC, Lust WD.

J Cereb Blood Flow Metab. 2008 Dec;28(12):1907-16. doi: 10.1038/jcbfm.2008.79. Epub 2008 Jul 23.

26.

Mitochondrial dysfunction in aging rat brain following transient global ischemia.

Xu K, Puchowicz MA, Sun X, LaManna JC.

Adv Exp Med Biol. 2008;614:379-86. doi: 10.1007/978-0-387-74911-2_42.

27.

Increased sensitivity to transient global ischemia in aging rat brain.

Xu K, Sun X, Puchowicz MA, LaManna JC.

Adv Exp Med Biol. 2007;599:199-206.

PMID:
17727265
28.

Mutations in the MPV17 gene are responsible for rapidly progressive liver failure in infancy.

Wong LJ, Brunetti-Pierri N, Zhang Q, Yazigi N, Bove KE, Dahms BB, Puchowicz MA, Gonzalez-Gomez I, Schmitt ES, Truong CK, Hoppel CL, Chou PC, Wang J, Baldwin EE, Adams D, Leslie N, Boles RG, Kerr DS, Craigen WJ.

Hepatology. 2007 Oct;46(4):1218-27. Erratum in: Hepatology. 2008 Feb;47(2):768.

PMID:
17694548
29.

Statistical analysis of metabolic pathways of brain metabolism at steady state.

Occhipinti R, Puchowicz MA, LaManna JC, Somersalo E, Calvetti D.

Ann Biomed Eng. 2007 Jun;35(6):886-902. Epub 2007 Mar 24.

PMID:
17385046
30.

Diet-induced ketosis increases capillary density without altered blood flow in rat brain.

Puchowicz MA, Xu K, Sun X, Ivy A, Emancipator D, LaManna JC.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1607-15. Epub 2007 Feb 6.

31.

Computational study on use of single-point analysis method for quantitating local cerebral blood flow in mice.

Puchowicz MA, Radhakrishnan K, Xu K, Magness DL, LaManna JC.

Adv Exp Med Biol. 2005;566:99-104.

PMID:
16594140
32.

Adaptation to chronic hypoxia during diet-induced ketosis.

Puchowicz MA, Emancipator DS, Xu K, Magness DL, Ndubuizu OI, Lust WD, LaManna JC.

Adv Exp Med Biol. 2005;566:51-7.

PMID:
16594134
33.

Adenosine treatment delays postischemic hippocampal CA1 loss after cardiac arrest and resuscitation in rats.

Xu K, Puchowicz MA, Lust WD, LaManna JC.

Brain Res. 2006 Feb 3;1071(1):208-17. Epub 2006 Jan 17.

PMID:
16412392
34.

Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria--case studies.

Puchowicz MA, Varnes ME, Cohen BH, Friedman NR, Kerr DS, Hoppel CL.

Mitochondrion. 2004 Sep;4(5-6):377-85.

PMID:
16120399
35.

Neuronal migration is transiently delayed by prenatal exposure to intermittent hypoxia.

Zechel JL, Gamboa JL, Peterson AG, Puchowicz MA, Selman WR, Lust WD.

Birth Defects Res B Dev Reprod Toxicol. 2005 Aug;74(4):287-99.

PMID:
16094620
36.

Renormalization of regional brain blood flow during prolonged mild hypoxic exposure in rats.

Xu K, Puchowicz MA, LaManna JC.

Brain Res. 2004 Nov 19;1027(1-2):188-91.

PMID:
15494170
37.

Comparison of glucose influx and blood flow in retina and brain of diabetic rats.

Puchowicz MA, Xu K, Magness D, Miller C, Lust WD, Kern TS, LaManna JC.

J Cereb Blood Flow Metab. 2004 Apr;24(4):449-57.

PMID:
15087714
38.

New secondary metabolites of phenylbutyrate in humans and rats.

Kasumov T, Brunengraber LL, Comte B, Puchowicz MA, Jobbins K, Thomas K, David F, Kinman R, Wehrli S, Dahms W, Kerr D, Nissim I, Brunengraber H.

Drug Metab Dispos. 2004 Jan;32(1):10-9.

PMID:
14709615
39.

Single-pass dual-label indicator method. Blood-to-brain transport of glucose and short-chain monocarboxylic acids.

Puchowicz MA, Xu K, LaManna JC.

Methods Mol Med. 2003;89:265-76. No abstract available.

PMID:
12958426
40.

Identification of phenylbutyrylglutamine, a new metabolite of phenylbutyrate metabolism in humans.

Comte B, Kasumov T, Pierce BA, Puchowicz MA, Scott ME, Dahms W, Kerr D, Nissim I, Brunengraber H.

J Mass Spectrom. 2002 Jun;37(6):581-90.

PMID:
12112740
41.

Dog model of therapeutic ketosis induced by oral administration of R,S-1,3-butanediol diacetoacetate.

Puchowicz MA, Smith CL, Bomont C, Koshy J, David F, Brunengraber H.

J Nutr Biochem. 2000 May;11(5):281-7.

PMID:
10876102
42.

Zonation of acetate labeling across the liver: implications for studies of lipogenesis by MIDA.

Puchowicz MA, Bederman IR, Comte B, Yang D, David F, Stone E, Jabbour K, Wasserman DH, Brunengraber H.

Am J Physiol. 1999 Dec;277(6):E1022-7. doi: 10.1152/ajpendo.1999.277.6.E1022.

PMID:
10600790
43.

15N enrichment of ammonium, glutamine-amide and urea, measured via mass isotopomer analysis of hexamethylenetetramine.

Yang D, Puchowicz MA, David F, Powers L, Halperin ML, Brunengraber H.

J Mass Spectrom. 1999 Nov;34(11):1130-6.

PMID:
10548807
44.

Tracing gluconeogenesis with deuterated water: measurement of low deuterium enrichments on carbons 6 and 2 of glucose.

Hazey JW, Yang D, Powers L, Previs SF, David F, Beaulieu AD, Puchowicz MA, Potter JL, Palmquist DL, Brunengraber H.

Anal Biochem. 1997 May 15;248(1):158-67.

PMID:
9177735

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