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Year Number of Results
1996 3
1997 8
1998 5
1999 14
2000 22
2001 37
2002 30
2003 32
2004 46
2005 44
2006 54
2007 62
2008 53
2009 63
2010 42
2011 24
2012 26
2013 24
2014 25
2015 35
2016 26
2017 39
2018 34
2019 25
2020 35
2021 31
2022 18
2023 25
2024 6

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792 results

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Page 1
Prostaglandin E(2) receptor PTGER4-expressing macrophages promote intestinal epithelial barrier regeneration upon inflammation.
Na YR, Jung D, Stakenborg M, Jang H, Gu GJ, Jeong MR, Suh SY, Kim HJ, Kwon YH, Sung TS, Ryoo SB, Park KJ, Im JP, Park JY, Lee YS, Han H, Park B, Lee S, Kim D, Lee HS, Cleynen I, Matteoli G, Seok SH. Na YR, et al. Gut. 2021 Dec;70(12):2249-2260. doi: 10.1136/gutjnl-2020-322146. Epub 2021 Feb 7. Gut. 2021. PMID: 33558271
The effect of PTGER4(+) macrophage secreted molecules was investigated on epithelial organoid differentiation. ...Csf1r-iCre Ptger4(fl/fl) mice showed defective mucosal healing and epithelial barrier regeneration in a model of DSS colitis. ...
The effect of PTGER4(+) macrophage secreted molecules was investigated on epithelial organoid differentiation. ...Csf1r-iCre Ptger …
Association of PTGER4 and PRKAA1 genetic polymorphisms with gastric cancer.
Yu S, Tu R, Chen Z, Song J, Li P, Hu F, Yuan G, Zhang R, Li Y. Yu S, et al. BMC Med Genomics. 2023 Sep 5;16(1):209. doi: 10.1186/s12920-023-01645-1. BMC Med Genomics. 2023. PMID: 37670284 Free PMC article.
BACKGROUND: Gastric cancer (GC) is one of the most common malignancies, affected by several genetic loci in the clinical phenotype. This study aimed to determine the association between PTGER4 and PRKAA1 gene polymorphisms and the risk of GC. METHODS: A total of 509 GC pat …
BACKGROUND: Gastric cancer (GC) is one of the most common malignancies, affected by several genetic loci in the clinical phenotype. This stu …
PTGER4 modulating variants in Crohn's disease.
Prager M, Büttner J, Büning C. Prager M, et al. Int J Colorectal Dis. 2014 Aug;29(8):909-15. doi: 10.1007/s00384-014-1881-3. Epub 2014 May 3. Int J Colorectal Dis. 2014. PMID: 24793213
PURPOSE: Variants modulating expression of the prostaglandin receptor 4 (PTGER4) have been reported to be associated with Cohn's disease (CD), but the clinical impact remains to be elucidated. ...No overall association to CD or UC was found for the rs4495224 variant. CONCL …
PURPOSE: Variants modulating expression of the prostaglandin receptor 4 (PTGER4) have been reported to be associated with Cohn's dise …
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche.
Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, Frommelt LS, Qu R, Knapp MS, Henriques A, Chalkidi N, Koliaraki V, Jiao J, Brewer JR, Bacher M, Blackburn HN, Zhao X, Breyer RM, Aidinis V, Jain D, Su B, Herschman HR, Kluger Y, Kollias G, Flavell RA. Roulis M, et al. Nature. 2020 Apr;580(7804):524-529. doi: 10.1038/s41586-020-2166-3. Epub 2020 Apr 1. Nature. 2020. PMID: 32322056 Free PMC article.
Using organoid experiments, we identified a molecular mechanism whereby PGE(2) promotes Yap dephosphorylation, nuclear translocation and transcriptional activity by signalling through the receptor Ptger4. Epithelial-specific ablation of Ptger4 misdirected the regene …
Using organoid experiments, we identified a molecular mechanism whereby PGE(2) promotes Yap dephosphorylation, nuclear translocation and tra …
PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts.
Rodriguez-Rodriguez L, Ivorra-Cortes J, Carmona FD, Martín J, Balsa A, van Steenbergen HW, van der Helm-van Mil AH, González-Álvaro I, Fernandez-Gutiérrez B. Rodriguez-Rodriguez L, et al. Arthritis Res Ther. 2015 Nov 5;17:306. doi: 10.1186/s13075-015-0830-z. Arthritis Res Ther. 2015. PMID: 26538147 Free PMC article.
INTRODUCTION: Prostaglandin E receptor 4 (PTGER4) is implicated in immune regulation and bone metabolism. The aim of this study was to analyze its role in radiological joint damage in rheumatoid arthritis (RA). ...Second, the PTGER4 gene and adjacent regions were an …
INTRODUCTION: Prostaglandin E receptor 4 (PTGER4) is implicated in immune regulation and bone metabolism. The aim of this study was t …
Association between PTGER4 polymorphisms and inflammatory bowel disease risk in Caucasian: A meta-analysis.
Wu PB, Qian R, Hong C, Guo YT, Yu YJ, Zhang G, Tan SY. Wu PB, et al. Medicine (Baltimore). 2020 Aug 21;99(34):e19756. doi: 10.1097/MD.0000000000019756. Medicine (Baltimore). 2020. PMID: 32846747 Free PMC article.
BACKGROUND: The results from previous studies on association between prostaglandin E receptor 4 (PTGER4) polymorphisms and inflammatory bowel disease (IBD) risk in Caucasian were conflict. ...
BACKGROUND: The results from previous studies on association between prostaglandin E receptor 4 (PTGER4) polymorphisms and inflammato …
Methylated PTGER4 is better than CA125, CEA, Cyfra211 and NSE as a therapeutic response assessment marker in stage IV lung cancer.
Zhang Y, Huang J, Zou Q, Che J, Yang K, Fan Q, Qian D, Wu J, Bao E, Song L, Zhang F. Zhang Y, et al. Oncol Lett. 2020 Apr;19(4):3229-3238. doi: 10.3892/ol.2020.11434. Epub 2020 Mar 3. Oncol Lett. 2020. PMID: 32256818 Free PMC article.
The results indicated that, following treatment, the blood levels of methylated PTGER4 and NSE had significantly decreased, and mPRGER4, CA125, CEA and NSE exhibited a significant decrease in percentage level. ...
The results indicated that, following treatment, the blood levels of methylated PTGER4 and NSE had significantly decreased, and mPRGE …
Cell-Free Methylated PTGER4 and SHOX2 Plasma DNA as a Biomarker for Therapy Monitoring and Prognosis in Advanced Stage NSCLC Patients.
Fleischhacker M, Arslan E, Reinicke D, Eisenmann S, Theil G, Kollmeier J, Schäper C, Grah C, Klawonn F, Holdenrieder S, Schmidt B. Fleischhacker M, et al. Diagnostics (Basel). 2023 Jun 21;13(13):2131. doi: 10.3390/diagnostics13132131. Diagnostics (Basel). 2023. PMID: 37443525 Free PMC article.
In our study, we aimed to answer these questions: (i) Is the quantification of free-circulating methylated PTGER4 and SHOX2 plasma DNA a useful method for therapy monitoring, and is this also possible for patients treated with different therapy regimens? ...
In our study, we aimed to answer these questions: (i) Is the quantification of free-circulating methylated PTGER4 and SHOX2 plasma DN …
792 results