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Items: 1 to 50 of 68

1.

Cardiometabolic Health and Longitudinal Progression of White Matter Hyperintensity: The Mayo Clinic Study of Aging.

Scharf EL, Graff-Radford J, Przybelski SA, Lesnick TG, Mielke MM, Knopman DS, Preboske GM, Schwarz CG, Senjem ML, Gunter JL, Machulda M, Kantarci K, Petersen RC, Jack CR Jr, Vemuri P.

Stroke. 2019 Sep 12:STROKEAHA119025822. doi: 10.1161/STROKEAHA.119.025822. [Epub ahead of print]

PMID:
31510903
2.

Amyloid, vascular, and resilience pathways associated with cognitive aging.

Vemuri P, Lesnick TG, Knopman DS, Przybelski SA, Reid RI, Mielke MM, Graff-Radford J, Lowe VJ, Machulda MM, Petersen RC, Jack CR Jr.

Ann Neurol. 2019 Sep 11. doi: 10.1002/ana.25600. [Epub ahead of print]

PMID:
31509621
3.

White matter hyperintensities: relationship to amyloid and tau burden.

Graff-Radford J, Arenaza-Urquijo EM, Knopman DS, Schwarz CG, Brown RD, Rabinstein AA, Gunter JL, Senjem ML, Przybelski SA, Lesnick T, Ward C, Mielke MM, Lowe VJ, Petersen RC, Kremers WK, Kantarci K, Jack CR, Vemuri P.

Brain. 2019 Aug 1;142(8):2483-2491. doi: 10.1093/brain/awz162.

PMID:
31199475
4.

Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease.

Lowe VJ, Lundt ES, Albertson SM, Przybelski SA, Senjem ML, Parisi JE, Kantarci K, Boeve B, Jones DT, Knopman D, Jack CR Jr, Dickson DW, Petersen RC, Murray ME.

Alzheimers Dement. 2019 Jul;15(7):927-939. doi: 10.1016/j.jalz.2019.03.016. Epub 2019 Jun 4.

PMID:
31175025
5.

Investigation of white matter PiB uptake as a marker of white matter integrity.

Zeydan B, Schwarz CG, Lowe VJ, Reid RI, Przybelski SA, Lesnick TG, Kremers WK, Senjem ML, Gunter JL, Min HK, Vemuri P, Knopman DS, Petersen RC, Jack CR Jr, Kantarci OH, Kantarci K.

Ann Clin Transl Neurol. 2019 Mar 3;6(4):678-688. doi: 10.1002/acn3.741. eCollection 2019 Apr.

6.

The metabolic brain signature of cognitive resilience in the 80+: beyond Alzheimer pathologies.

Arenaza-Urquijo EM, Przybelski SA, Lesnick TL, Graff-Radford J, Machulda MM, Knopman DS, Schwarz CG, Lowe VJ, Mielke MM, Petersen RC, Jack CR, Vemuri P.

Brain. 2019 Apr 1;142(4):1134-1147. doi: 10.1093/brain/awz037.

PMID:
30851100
7.

18 F-AV-1451 uptake differs between dementia with lewy bodies and posterior cortical atrophy.

Nedelska Z, Josephs KA, Graff-Radford J, Przybelski SA, Lesnick TG, Boeve BF, Drubach DA, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Whitwell JL, Kantarci K.

Mov Disord. 2019 Mar;34(3):344-352. doi: 10.1002/mds.27603. Epub 2019 Jan 7.

8.

Cerebral microbleeds: Prevalence and relationship to amyloid burden.

Graff-Radford J, Botha H, Rabinstein AA, Gunter JL, Przybelski SA, Lesnick T, Huston J 3rd, Flemming KD, Preboske GM, Senjem ML, Brown RD Jr, Mielke MM, Roberts RO, Lowe VJ, Knopman DS, Petersen RC, Kremers W, Vemuri P, Jack CR Jr, Kantarci K.

Neurology. 2019 Jan 15;92(3):e253-e262. doi: 10.1212/WNL.0000000000006780. Epub 2018 Dec 19.

PMID:
30568001
9.

Development of a cerebrovascular magnetic resonance imaging biomarker for cognitive aging.

Vemuri P, Lesnick TG, Przybelski SA, Graff-Radford J, Reid RI, Lowe VJ, Zuk SM, Senjem ML, Schwarz CG, Gunter JL, Kantarci K, Machulda MM, Mielke MM, Petersen RC, Knopman DS, Jack CR Jr.

Ann Neurol. 2018 Nov;84(5):705-716. doi: 10.1002/ana.25346. Epub 2018 Oct 25.

10.

Statins and Brain Health: Alzheimer's Disease and Cerebrovascular Disease Biomarkers in Older Adults.

Ramanan VK, Przybelski SA, Graff-Radford J, Castillo AM, Lowe VJ, Mielke MM, Roberts RO, Reid RI, Knopman DS, Jack CR, Petersen RC, Vemuri P.

J Alzheimers Dis. 2018;65(4):1345-1352. doi: 10.3233/JAD-180446.

11.

Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: Associations with clinical severity, glucose metabolism and tau PET.

Nedelska Z, Senjem ML, Przybelski SA, Lesnick TG, Lowe VJ, Boeve BF, Arani A, Vemuri P, Graff-Radford J, Ferman TJ, Jones DT, Savica R, Knopman DS, Petersen RC, Jack CR, Kantarci K.

Neuroimage Clin. 2018 Jun 19;19:939-947. doi: 10.1016/j.nicl.2018.06.020. eCollection 2018.

12.

White Matter Reference Region in PET Studies of 11C-Pittsburgh Compound B Uptake: Effects of Age and Amyloid-β Deposition.

Lowe VJ, Lundt ES, Senjem ML, Schwarz CG, Min HK, Przybelski SA, Kantarci K, Knopman D, Petersen RC, Jack CR Jr.

J Nucl Med. 2018 Oct;59(10):1583-1589. doi: 10.2967/jnumed.117.204271. Epub 2018 Apr 19.

13.

FDG-PET in tau-negative amnestic dementia resembles that of autopsy-proven hippocampal sclerosis.

Botha H, Mantyh WG, Murray ME, Knopman DS, Przybelski SA, Wiste HJ, Graff-Radford J, Josephs KA, Schwarz CG, Kremers WK, Boeve BF, Petersen RC, Machulda MM, Parisi JE, Dickson DW, Lowe V, Jack CR Jr, Jones DT.

Brain. 2018 Apr 1;141(4):1201-1217. doi: 10.1093/brain/awy049.

14.

Association of Excessive Daytime Sleepiness With Longitudinal β-Amyloid Accumulation in Elderly Persons Without Dementia.

Carvalho DZ, St Louis EK, Knopman DS, Boeve BF, Lowe VJ, Roberts RO, Mielke MM, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr, Vemuri P.

JAMA Neurol. 2018 Jun 1;75(6):672-680. doi: 10.1001/jamaneurol.2018.0049.

15.

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia.

Botha H, Mantyh WG, Graff-Radford J, Machulda MM, Przybelski SA, Wiste HJ, Senjem ML, Parisi JE, Petersen RC, Murray ME, Boeve BF, Lowe VJ, Knopman DS, Jack CR Jr, Jones DT.

Neurology. 2018 Mar 13;90(11):e940-e946. doi: 10.1212/WNL.0000000000005124. Epub 2018 Feb 7.

16.

Frequency of Acute and Subacute Infarcts in a Population-Based Study.

Arnold Fiebelkorn C, Vemuri P, Rabinstein AA, Mielke MM, Przybelski SA, Kantarci K, Jones DT, Brown RD Jr, Knopman DS, Petersen RC, Jack CR Jr, Graff-Radford J.

Mayo Clin Proc. 2018 Mar;93(3):300-306. doi: 10.1016/j.mayocp.2017.11.021. Epub 2018 Feb 14.

17.

Sex differences in cerebrovascular pathologies on FLAIR in cognitively unimpaired elderly.

Fatemi F, Kantarci K, Graff-Radford J, Preboske GM, Weigand SD, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Mielke MM, Petersen RC, Jack CR Jr, Vemuri P.

Neurology. 2018 Feb 6;90(6):e466-e473. doi: 10.1212/WNL.0000000000004913. Epub 2018 Jan 17.

18.

Association Between Microinfarcts and Blood Pressure Trajectories.

Graff-Radford J, Raman MR, Rabinstein AA, Przybelski SA, Lesnick TG, Boeve BF, Murray ME, Dickson DW, Reichard RR, Parisi JE, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K.

JAMA Neurol. 2018 Feb 1;75(2):212-218. doi: 10.1001/jamaneurol.2017.3392.

19.

Age, vascular health, and Alzheimer disease biomarkers in an elderly sample.

Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Lowe VJ, Graff-Radford J, Roberts RO, Mielke MM, Machulda MM, Petersen RC, Jack CR Jr.

Ann Neurol. 2017 Nov;82(5):706-718. doi: 10.1002/ana.25071. Epub 2017 Oct 26.

20.

1H-MRS metabolites and rate of β-amyloid accumulation on serial PET in clinically normal adults.

Nedelska Z, Przybelski SA, Lesnick TG, Schwarz CG, Lowe VJ, Machulda MM, Kremers WK, Mielke MM, Roberts RO, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K.

Neurology. 2017 Sep 26;89(13):1391-1399. doi: 10.1212/WNL.0000000000004421. Epub 2017 Aug 25.

21.

White-matter integrity on DTI and the pathologic staging of Alzheimer's disease.

Kantarci K, Murray ME, Schwarz CG, Reid RI, Przybelski SA, Lesnick T, Zuk SM, Raman MR, Senjem ML, Gunter JL, Boeve BF, Knopman DS, Parisi JE, Petersen RC, Jack CR Jr, Dickson DW.

Neurobiol Aging. 2017 Aug;56:172-179. doi: 10.1016/j.neurobiolaging.2017.04.024. Epub 2017 May 4.

22.

Cortical Thickness and Depressive Symptoms in Cognitively Normal Individuals: The Mayo Clinic Study of Aging.

Pink A, Przybelski SA, Krell-Roesch J, Stokin GB, Roberts RO, Mielke MM, Knopman DS, Jack CR, Petersen RC, Geda YE.

J Alzheimers Dis. 2017;58(4):1273-1281. doi: 10.3233/JAD-170041.

23.

Pittsburgh compound-B PET white matter imaging and cognitive function in late multiple sclerosis.

Zeydan B, Lowe VJ, Schwarz CG, Przybelski SA, Tosakulwong N, Zuk SM, Senjem ML, Gunter JL, Roberts RO, Mielke MM, Benarroch EE, Rodriguez M, Machulda MM, Lesnick TG, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K, Kantarci OH.

Mult Scler. 2018 May;24(6):739-749. doi: 10.1177/1352458517707346. Epub 2017 May 5.

24.

Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals.

Vemuri P, Knopman DS, Lesnick TG, Przybelski SA, Mielke MM, Graff-Radford J, Murray ME, Roberts RO, Vassilaki M, Lowe VJ, Machulda MM, Jones DT, Petersen RC, Jack CR Jr.

JAMA Neurol. 2017 Jun 1;74(6):718-726. doi: 10.1001/jamaneurol.2017.0244.

25.

Tau-PET uptake: Regional variation in average SUVR and impact of amyloid deposition.

Vemuri P, Lowe VJ, Knopman DS, Senjem ML, Kemp BJ, Schwarz CG, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr.

Alzheimers Dement (Amst). 2016 Dec 21;6:21-30. doi: 10.1016/j.dadm.2016.12.010. eCollection 2017.

26.

Excessive daytime sleepiness and fatigue may indicate accelerated brain aging in cognitively normal late middle-aged and older adults.

Carvalho DZ, St Louis EK, Boeve BF, Mielke MM, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Geda YE, Petersen RC, Jack CR Jr, Vemuri P.

Sleep Med. 2017 Apr;32:236-243. doi: 10.1016/j.sleep.2016.08.023. Epub 2016 Nov 3.

27.

A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity.

Schwarz CG, Gunter JL, Wiste HJ, Przybelski SA, Weigand SD, Ward CP, Senjem ML, Vemuri P, Murray ME, Dickson DW, Parisi JE, Kantarci K, Weiner MW, Petersen RC, Jack CR Jr; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage Clin. 2016 May 30;11:802-812. doi: 10.1016/j.nicl.2016.05.017. eCollection 2016.

28.

Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment.

Kantarci K, Lesnick T, Ferman TJ, Przybelski SA, Boeve BF, Smith GE, Kremers WK, Knopman DS, Jack CR Jr, Petersen RC.

Neurology. 2016 Nov 29;87(22):2317-2323. Epub 2016 Nov 2.

29.

Cortical Thickness and Anxiety Symptoms Among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging.

Pink A, Przybelski SA, Krell-Roesch J, Stokin GB, Roberts RO, Mielke MM, Spangehl KA, Knopman DS, Jack CR Jr, Petersen RC, Geda YE.

J Neuropsychiatry Clin Neurosci. 2017 Winter;29(1):60-66. doi: 10.1176/appi.neuropsych.15100378. Epub 2016 Aug 31.

30.

An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease.

Sarro L, Tosakulwong N, Schwarz CG, Graff-Radford J, Przybelski SA, Lesnick TG, Zuk SM, Reid RI, Raman MR, Boeve BF, Ferman TJ, Knopman DS, Comi G, Filippi M, Murray ME, Parisi JE, Dickson DW, Petersen RC, Jack CR Jr, Kantarci K.

Alzheimers Dement. 2017 Mar;13(3):257-266. doi: 10.1016/j.jalz.2016.07.003. Epub 2016 Aug 10.

31.

Amyloid-β deposition and regional grey matter atrophy rates in dementia with Lewy bodies.

Sarro L, Senjem ML, Lundt ES, Przybelski SA, Lesnick TG, Graff-Radford J, Boeve BF, Lowe VJ, Ferman TJ, Knopman DS, Comi G, Filippi M, Petersen RC, Jack CR Jr, Kantarci K.

Brain. 2016 Oct;139(Pt 10):2740-2750. Epub 2016 Jul 24.

32.

Predicting Survival in Dementia With Lewy Bodies With Hippocampal Volumetry.

Graff-Radford J, Lesnick TG, Boeve BF, Przybelski SA, Jones DT, Senjem ML, Gunter JL, Ferman TJ, Knopman DS, Murray ME, Dickson DW, Sarro L, Jack CR Jr, Petersen RC, Kantarci K.

Mov Disord. 2016 Jul;31(7):989-94. doi: 10.1002/mds.26666. Epub 2016 May 23.

33.

Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study.

Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Machulda M, Lowe VJ, Mielke MM, Roberts RO, Gunter JL, Senjem ML, Geda YE, Rocca WA, Petersen RC, Jack CR Jr.

Neurology. 2016 Mar 22;86(12):1128-35. doi: 10.1212/WNL.0000000000002490. Epub 2016 Feb 24.

34.

Characterizing White Matter Tract Degeneration in Syndromic Variants of Alzheimer's Disease: A Diffusion Tensor Imaging Study.

Madhavan A, Schwarz CG, Duffy JR, Strand EA, Machulda MM, Drubach DA, Kantarci K, Przybelski SA, Reid RI, Senjem ML, Gunter JL, Apostolova LG, Lowe VJ, Petersen RC, Jack CR, Josephs KA, Whitwell JL.

J Alzheimers Dis. 2016;49(3):633-43. doi: 10.3233/JAD-150502.

PMID:
26484918
35.

Frequency and topography of cerebral microbleeds in dementia with Lewy bodies compared to Alzheimer's disease.

Gungor I, Sarro L, Graff-Radford J, Zuk SM, Tosakulwong N, Przybelski SA, Lesnick T, Boeve BF, Ferman TJ, Smith GE, Knopman DS, Filippi M, Petersen RC, Jack CR Jr, Kantarci K.

Parkinsonism Relat Disord. 2015 Sep;21(9):1101-4. doi: 10.1016/j.parkreldis.2015.07.008. Epub 2015 Jul 14.

36.

White matter integrity in dementia with Lewy bodies: a voxel-based analysis of diffusion tensor imaging.

Nedelska Z, Schwarz CG, Boeve BF, Lowe VJ, Reid RI, Przybelski SA, Lesnick TG, Gunter JL, Senjem ML, Ferman TJ, Smith GE, Geda YE, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K.

Neurobiol Aging. 2015 Jun;36(6):2010-7. doi: 10.1016/j.neurobiolaging.2015.03.007. Epub 2015 Mar 14.

37.

Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum.

Murray ME, Lowe VJ, Graff-Radford NR, Liesinger AM, Cannon A, Przybelski SA, Rawal B, Parisi JE, Petersen RC, Kantarci K, Ross OA, Duara R, Knopman DS, Jack CR Jr, Dickson DW.

Brain. 2015 May;138(Pt 5):1370-81. doi: 10.1093/brain/awv050. Epub 2015 Mar 23.

38.

Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly.

Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Preboske GM, Kantarci K, Raman MR, Machulda MM, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Rocca WA, Roberts RO, Petersen RC, Jack CR Jr.

Brain. 2015 Mar;138(Pt 3):761-71. doi: 10.1093/brain/awu393. Epub 2015 Jan 15.

39.

Working memory and language network dysfunctions in logopenic aphasia: a task-free fMRI comparison with Alzheimer's dementia.

Whitwell JL, Jones DT, Duffy JR, Strand EA, Machulda MM, Przybelski SA, Vemuri P, Gregg BE, Gunter JL, Senjem ML, Petersen RC, Jack CR Jr, Josephs KA.

Neurobiol Aging. 2015 Mar;36(3):1245-52. doi: 10.1016/j.neurobiolaging.2014.12.013. Epub 2014 Dec 16.

40.

Early Alzheimer's disease neuropathology detected by proton MR spectroscopy.

Murray ME, Przybelski SA, Lesnick TG, Liesinger AM, Spychalla A, Zhang B, Gunter JL, Parisi JE, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Dickson DW, Kantarci K.

J Neurosci. 2014 Dec 3;34(49):16247-55. doi: 10.1523/JNEUROSCI.2027-14.2014.

41.

White matter integrity determined with diffusion tensor imaging in older adults without dementia: influence of amyloid load and neurodegeneration.

Kantarci K, Schwarz CG, Reid RI, Przybelski SA, Lesnick TG, Zuk SM, Senjem ML, Gunter JL, Lowe V, Machulda MM, Knopman DS, Petersen RC, Jack CR Jr.

JAMA Neurol. 2014 Dec;71(12):1547-54. doi: 10.1001/jamaneurol.2014.1482.

42.

Pattern of brain atrophy rates in autopsy-confirmed dementia with Lewy bodies.

Nedelska Z, Ferman TJ, Boeve BF, Przybelski SA, Lesnick TG, Murray ME, Gunter JL, Senjem ML, Vemuri P, Smith GE, Geda YE, Graff-Radford J, Knopman DS, Petersen RC, Parisi JE, Dickson DW, Jack CR Jr, Kantarci K.

Neurobiol Aging. 2015 Jan;36(1):452-61. doi: 10.1016/j.neurobiolaging.2014.07.005. Epub 2014 Jul 15.

43.

Dementia with Lewy bodies: basis of cingulate island sign.

Graff-Radford J, Murray ME, Lowe VJ, Boeve BF, Ferman TJ, Przybelski SA, Lesnick TG, Senjem ML, Gunter JL, Smith GE, Knopman DS, Jack CR Jr, Dickson DW, Petersen RC, Kantarci K.

Neurology. 2014 Aug 26;83(9):801-9. doi: 10.1212/WNL.0000000000000734. Epub 2014 Jul 23.

44.

Association of lifetime intellectual enrichment with cognitive decline in the older population.

Vemuri P, Lesnick TG, Przybelski SA, Machulda M, Knopman DS, Mielke MM, Roberts RO, Geda YE, Rocca WA, Petersen RC, Jack CR Jr.

JAMA Neurol. 2014 Aug;71(8):1017-24. doi: 10.1001/jamaneurol.2014.963.

45.

Antemortem MRI findings associated with microinfarcts at autopsy.

Raman MR, Preboske GM, Przybelski SA, Gunter JL, Senjem ML, Vemuri P, Murphy MC, Murray ME, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Dickson DW, Jack CR Jr, Kantarci K.

Neurology. 2014 Jun 3;82(22):1951-8. doi: 10.1212/WNL.0000000000000471. Epub 2014 May 2.

46.

Improved DTI registration allows voxel-based analysis that outperforms tract-based spatial statistics.

Schwarz CG, Reid RI, Gunter JL, Senjem ML, Przybelski SA, Zuk SM, Whitwell JL, Vemuri P, Josephs KA, Kantarci K, Thompson PM, Petersen RC, Jack CR Jr; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage. 2014 Jul 1;94:65-78. doi: 10.1016/j.neuroimage.2014.03.026. Epub 2014 Mar 18.

47.

Association of type 2 diabetes with brain atrophy and cognitive impairment.

Roberts RO, Knopman DS, Przybelski SA, Mielke MM, Kantarci K, Preboske GM, Senjem ML, Pankratz VS, Geda YE, Boeve BF, Ivnik RJ, Rocca WA, Petersen RC, Jack CR Jr.

Neurology. 2014 Apr 1;82(13):1132-41. doi: 10.1212/WNL.0000000000000269. Epub 2014 Mar 19.

48.

MRI and pathology of REM sleep behavior disorder in dementia with Lewy bodies.

Murray ME, Ferman TJ, Boeve BF, Przybelski SA, Lesnick TG, Liesinger AM, Senjem ML, Gunter JL, Preboske GM, Lowe VJ, Vemuri P, Dugger BN, Knopman DS, Smith GE, Parisi JE, Silber MH, Graff-Radford NR, Petersen RC, Jack CR Jr, Dickson DW, Kantarci K.

Neurology. 2013 Nov 5;81(19):1681-9. doi: 10.1212/01.wnl.0000435299.57153.f0. Epub 2013 Oct 9.

49.

MRI and MRS predictors of mild cognitive impairment in a population-based sample.

Kantarci K, Weigand SD, Przybelski SA, Preboske GM, Pankratz VS, Vemuri P, Senjem ML, Murphy MC, Gunter JL, Machulda MM, Ivnik RJ, Roberts RO, Boeve BF, Rocca WA, Knopman DS, Petersen RC, Jack CR Jr.

Neurology. 2013 Jul 9;81(2):126-33. doi: 10.1212/WNL.0b013e31829a3329. Epub 2013 Jun 12.

50.

Effect of lifestyle activities on Alzheimer disease biomarkers and cognition.

Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Roberts RO, Lowe VJ, Kantarci K, Senjem ML, Gunter JL, Boeve BF, Petersen RC, Jack CR Jr.

Ann Neurol. 2012 Nov;72(5):730-8. doi: 10.1002/ana.23665.

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