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Items: 25

1.

Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance.

Sabrautzki S, Kaiser G, Przemeck GKH, Gerst F, Lorza-Gil E, Panse M, Sartorius T, Hoene M, Marschall S, Häring HU, Hrabě de Angelis M, Ullrich S.

Mol Metab. 2017 Oct;6(10):1304-1312. doi: 10.1016/j.molmet.2017.07.007. Epub 2017 Jul 18.

2.

Modeling coexistence of oscillation and Delta/Notch-mediated lateral inhibition in pancreas development and neurogenesis.

Tiedemann HB, Schneltzer E, Beckers J, Przemeck GKH, Hrabě de Angelis M.

J Theor Biol. 2017 Oct 7;430:32-44. doi: 10.1016/j.jtbi.2017.06.006. Epub 2017 Jun 23.

3.

The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.

Fuchs H, Sabrautzki S, Przemeck GK, Leuchtenberger S, Lorenz-Depiereux B, Becker L, Rathkolb B, Horsch M, Garrett L, Östereicher MA, Hans W, Abe K, Sagawa N, Rozman J, Vargas-Panesso IL, Sandholzer M, Lisse TS, Adler T, Aguilar-Pimentel JA, Calzada-Wack J, Ehrhard N, Elvert R, Gau C, Hölter SM, Micklich K, Moreth K, Prehn C, Puk O, Racz I, Stoeger C, Vernaleken A, Michel D, Diener S, Wieland T, Adamski J, Bekeredjian R, Busch DH, Favor J, Graw J, Klingenspor M, Lengger C, Maier H, Neff F, Ollert M, Stoeger T, Yildirim AÖ, Strom TM, Zimmer A, Wolf E, Wurst W, Klopstock T, Beckers J, Gailus-Durner V, Hrabé de Angelis M.

G3 (Bethesda). 2016 Dec 7;6(12):4035-4046. doi: 10.1534/g3.116.033670.

4.

Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.

Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M.

Diabetes. 2016 Sep;65(9):2540-52. doi: 10.2337/db15-1670. Epub 2016 Jun 9.

5.

Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia.

Diener S, Bayer S, Sabrautzki S, Wieland T, Mentrup B, Przemeck GK, Rathkolb B, Graf E, Hans W, Fuchs H, Horsch M, Schwarzmayr T, Wolf E, Klopocki E, Jakob F, Strom TM, Hrabě de Angelis M, Lorenz-Depiereux B.

Mamm Genome. 2016 Apr;27(3-4):111-21. doi: 10.1007/s00335-016-9619-x. Epub 2016 Jan 23.

PMID:
26803617
6.

Fast synchronization of ultradian oscillators controlled by delta-notch signaling with cis-inhibition.

Tiedemann HB, Schneltzer E, Zeiser S, Wurst W, Beckers J, Przemeck GK, Hrabě de Angelis M.

PLoS Comput Biol. 2014 Oct 2;10(10):e1003843. doi: 10.1371/journal.pcbi.1003843. eCollection 2014 Oct.

7.

Prdm6 is essential for cardiovascular development in vivo.

Gewies A, Castineiras-Vilarino M, Ferch U, Jährling N, Heinrich K, Hoeckendorf U, Przemeck GK, Munding M, Groß O, Schroeder T, Horsch M, Karran EL, Majid A, Antonowicz S, Beckers J, Hrabé de Angelis M, Dodt HU, Peschel C, Förster I, Dyer MJ, Ruland J.

PLoS One. 2013 Nov 21;8(11):e81833. doi: 10.1371/journal.pone.0081833. eCollection 2013.

8.

In vitro analysis of bone phenotypes in Col1a1 and Jagged1 mutant mice using a standardized osteoblast cell culture system.

Thiele F, Cohrs CM, Przemeck GK, Wurst W, Fuchs H, Hrabé de Angelis M.

J Bone Miner Metab. 2013 May;31(3):293-303. doi: 10.1007/s00774-012-0421-x. Epub 2013 Jan 31.

PMID:
23371561
9.

From dynamic expression patterns to boundary formation in the presomitic mesoderm.

Tiedemann HB, Schneltzer E, Zeiser S, Hoesel B, Beckers J, Przemeck GK, de Angelis MH.

PLoS Comput Biol. 2012;8(6):e1002586. doi: 10.1371/journal.pcbi.1002586. Epub 2012 Jun 28.

10.

Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms.

Thiele F, Cohrs CM, Flor A, Lisse TS, Przemeck GK, Horsch M, Schrewe A, Gailus-Durner V, Ivandic B, Katus HA, Wurst W, Reisenberg C, Chaney H, Fuchs H, Hans W, Beckers J, Marini JC, Hrabé de Angelis M.

Hum Mol Genet. 2012 Aug 15;21(16):3535-45. doi: 10.1093/hmg/dds183. Epub 2012 May 15.

11.

Combination of in silico and in situ hybridisation approaches to identify potential Dll1 associated miRNAs during mouse embryogenesis.

Hoesel B, Bhujabal Z, Przemeck GK, Kurz-Drexler A, Weisenhorn DM, Angelis MH, Beckers J.

Gene Expr Patterns. 2010 Sep;10(6):265-73. doi: 10.1016/j.gep.2010.06.002. Epub 2010 Jun 15.

PMID:
20558326
12.

Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression.

Marklund U, Hansson EM, Sundström E, de Angelis MH, Przemeck GK, Lendahl U, Muhr J, Ericson J.

Development. 2010 Feb;137(3):437-45. doi: 10.1242/dev.036806.

13.

Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes.

Rubio-Aliaga I, Przemeck GK, Fuchs H, Gailus-Durner V, Adler T, Hans W, Horsch M, Rathkolb B, Rozman J, Schrewe A, Wagner S, Hoelter SM, Becker L, Klopstock T, Wurst W, Wolf E, Klingenspor M, Ivandic BT, Busch DH, Beckers J, Hrabé de Angelis M.

PLoS One. 2009 Jun 29;4(6):e6054. doi: 10.1371/journal.pone.0006054.

14.

The CALM and CALM/AF10 interactor CATS is a marker for proliferation.

Archangelo LF, Greif PA, Hölzel M, Harasim T, Kremmer E, Przemeck GK, Eick D, Deshpande AJ, Buske C, de Angelis MH, Saad ST, Bohlander SK.

Mol Oncol. 2008 Dec;2(4):356-67. doi: 10.1016/j.molonc.2008.08.001. Epub 2008 Sep 4.

15.

ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta.

Lisse TS, Thiele F, Fuchs H, Hans W, Przemeck GK, Abe K, Rathkolb B, Quintanilla-Martinez L, Hoelzlwimmer G, Helfrich M, Wolf E, Ralston SH, Hrabé de Angelis M.

PLoS Genet. 2008 Feb;4(2):e7. doi: 10.1371/journal.pgen.0040007.

16.

Cell-based simulation of dynamic expression patterns in the presomitic mesoderm.

Tiedemann HB, Schneltzer E, Zeiser S, Rubio-Aliaga I, Wurst W, Beckers J, Przemeck GK, Hrabé de Angelis M.

J Theor Biol. 2007 Sep 7;248(1):120-9. Epub 2007 May 21.

PMID:
17575987
17.

A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse.

Rubio-Aliaga I, Soewarto D, Wagner S, Klaften M, Fuchs H, Kalaydjiev S, Busch DH, Klempt M, Rathkolb B, Wolf E, Abe K, Zeiser S, Przemeck GK, Beckers J, de Angelis MH.

Genetics. 2007 Mar;175(3):1451-63. Epub 2006 Dec 18.

18.

Number of active transcription factor binding sites is essential for the Hes7 oscillator.

Zeiser S, Liebscher HV, Tiedemann H, Rubio-Aliaga I, Przemeck GK, de Angelis MH, Winkler G.

Theor Biol Med Model. 2006 Feb 23;3:11.

19.

Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development.

Jakupoglu C, Przemeck GK, Schneider M, Moreno SG, Mayr N, Hatzopoulos AK, de Angelis MH, Wurst W, Bornkamm GW, Brielmeier M, Conrad M.

Mol Cell Biol. 2005 Mar;25(5):1980-8.

20.

Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality.

Willer T, Prados B, Falcón-Pérez JM, Renner-Müller I, Przemeck GK, Lommel M, Coloma A, Valero MC, de Angelis MH, Tanner W, Wolf E, Strahl S, Cruces J.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14126-31. Epub 2004 Sep 21.

21.

Interaction of the MAGUK family member Acvrinp1 and the cytoplasmic domain of the Notch ligand Delta1.

Pfister S, Przemeck GK, Gerber JK, Beckers J, Adamski J, Hrabé de Angelis M.

J Mol Biol. 2003 Oct 17;333(2):229-35.

PMID:
14529612
22.

Genetic complexity of cellulose synthase a gene function in Arabidopsis embryogenesis.

Beeckman T, Przemeck GK, Stamatiou G, Lau R, Terryn N, De Rycke R, Inzé D, Berleth T.

Plant Physiol. 2002 Dec;130(4):1883-93.

23.

Node and midline defects are associated with left-right development in Delta1 mutant embryos.

Przemeck GK, Heinzmann U, Beckers J, Hrabé de Angelis M.

Development. 2003 Jan;130(1):3-13.

24.

Isolation and characterization of a novel gene from the DiGeorge chromosomal region that encodes for a mediator subunit.

Berti L, Mittler G, Przemeck GK, Stelzer G, Günzler B, Amati F, Conti E, Dallapiccola B, Hrabé de Angelis M, Novelli G, Meisterernst M.

Genomics. 2001 Jun 15;74(3):320-32.

PMID:
11414760
25.

Studies on the role of the Arabidopsis gene MONOPTEROS in vascular development and plant cell axialization.

Przemeck GK, Mattsson J, Hardtke CS, Sung ZR, Berleth T.

Planta. 1996;200(2):229-37.

PMID:
8904808

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