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Items: 1 to 50 of 76

1.

Evaluation of fetal and maternal vancomycin-induced kidney injury during pregnancy in a rat model.

Joshi MD, Pais GM, Chang J, Hlukhenka K, Avedissian SN, Gulati A, Prozialeck WC, Lamar PC, Zhang Z, Scheetz MH, Griffin B.

Antimicrob Agents Chemother. 2019 Jul 22. pii: AAC.00761-19. doi: 10.1128/AAC.00761-19. [Epub ahead of print]

PMID:
31332061
2.

Levels of Cadmium in Human Mandibular Bone.

Browar AW, Leavitt LL, Prozialeck WC, Edwards JR.

Toxics. 2019 Jun 4;7(2). pii: E31. doi: 10.3390/toxics7020031.

3.

Kratom policy: The challenge of balancing therapeutic potential with public safety.

Prozialeck WC, Avery BA, Boyer EW, Grundmann O, Henningfield JE, Kruegel AC, McMahon LR, McCurdy CR, Swogger MT, Veltri CA, Singh D.

Int J Drug Policy. 2019 Aug;70:70-77. doi: 10.1016/j.drugpo.2019.05.003. Epub 2019 May 16.

4.

Twenty-four hour pharmacokinetic relationships for intravenous vancomycin and novel urinary biomarkers of acute kidney injury in a rat model.

Avedissian SN, Pais GM, O'Donnell JN, Lodise TP, Liu J, Prozialeck WC, Joshi MD, Lamar PC, Becher L, Gulati A, Hope W, Scheetz MH.

J Antimicrob Chemother. 2019 Aug 1;74(8):2326-2334. doi: 10.1093/jac/dkz167.

PMID:
31065686
5.

Self-reported prevalence and severity of opioid and kratom (Mitragyna speciosa korth.) side effects.

Saref A, Suraya S, Singh D, Grundmann O, Narayanan S, Swogger MT, Prozialeck WC, Boyer E, Chear NJY, Balasingam V.

J Ethnopharmacol. 2019 Jun 28;238:111876. doi: 10.1016/j.jep.2019.111876. Epub 2019 Apr 20.

PMID:
31014959
6.

Comparative Performance of Urinary Biomarkers for Vancomycin-Induced Kidney Injury According to Timeline of Injury.

Pais GM, Avedissian SN, O'Donnell JN, Rhodes NJ, Lodise TP, Prozialeck WC, Lamar PC, Cluff C, Gulati A, Fitzgerald JC, Downes KJ, Zuppa AF, Scheetz MH.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00079-19. doi: 10.1128/AAC.00079-19. Print 2019 Jul.

PMID:
30988153
7.

The One Health Initiative as a Basis for Research Development in the Department of Pharmacology at Midwestern University.

Prozialeck WC, Edwards JR.

J Am Osteopath Assoc. 2018 Sep 1;118(9):610-616. doi: 10.7556/jaoa.2018.135.

PMID:
30178051
8.

Cadmium Exposure Disrupts Periodontal Bone in Experimental Animals: Implications for Periodontal Disease in Humans.

Browar AW, Koufos EB, Wei Y, Leavitt LL, Prozialeck WC, Edwards JR.

Toxics. 2018 Jun 13;6(2). pii: E32. doi: 10.3390/toxics6020032.

9.

Severity of Pain and Sleep Problems during Kratom (Mitragyna speciosa Korth.) Cessation among Regular Kratom Users.

Singh D, Narayanan S, Vicknasingam BK, Prozialeck WC, Ramanathan S, Zainal H, Harun SN.

J Psychoactive Drugs. 2018 Jul-Aug;50(3):266-274. doi: 10.1080/02791072.2018.1443234. Epub 2018 Mar 20.

PMID:
29558272
10.

Cadmium Nephrotoxicity Is Associated with Altered MicroRNA Expression in the Rat Renal Cortex.

Fay MJ, Alt LAC, Ryba D, Salamah R, Peach R, Papaeliou A, Zawadzka S, Weiss A, Patel N, Rahman A, Stubbs-Russell Z, Lamar PC, Edwards JR, Prozialeck WC.

Toxics. 2018 Mar 15;6(1). pii: E16. doi: 10.3390/toxics6010016.

11.

Effects of sub-chronic Cd exposure on levels of copper, selenium, zinc, iron and other essential metals in rat renal cortex.

Prozialeck WC, Lamar PC, Edwards JR.

Toxicol Rep. 2016 Sep 12;3:740-746. doi: 10.1016/j.toxrep.2016.09.005. eCollection 2016.

12.

24-Hour Pharmacokinetic Relationships for Vancomycin and Novel Urinary Biomarkers of Acute Kidney Injury.

O'Donnell JN, Rhodes NJ, Lodise TP, Prozialeck WC, Miglis CM, Joshi MD, Venkatesan N, Pais G, Cluff C, Lamar PC, Briyal S, Day JZ, Gulati A, Scheetz MH.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e00416-17. doi: 10.1128/AAC.00416-17. Print 2017 Nov.

13.

One Health: Children, Waterfowl, and Lead Exposure in Northwestern Nigeria.

Edwards JR, Fossum TW, Nichols KJ, Noah DL, Tarpley RJ, Prozialeck WC.

J Am Osteopath Assoc. 2017 Jun 1;117(6):370-376. doi: 10.7556/jaoa.2017.075. Review.

PMID:
28556859
14.

Correction for Rhodes et al., Evaluation of Vancomycin Exposures Associated with Elevations in Novel Urinary Biomarkers of Acute Kidney Injury in Vancomycin-Treated Rats.

Rhodes NJ, Prozialeck WC, Lodise TP, Venkatesan N, O'Donnell JN, Pais G, Cluff C, Lamar PC, Neely MN, Gulati A, Scheetz MH.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e00185-17. doi: 10.1128/AAC.00185-17. Print 2017 Apr. No abstract available.

15.

Update on the Pharmacology and Legal Status of Kratom.

Prozialeck WC.

J Am Osteopath Assoc. 2016 Dec 1;116(12):802-809. doi: 10.7556/jaoa.2016.156.

PMID:
27893147
16.

Evaluation of Vancomycin Exposures Associated with Elevations in Novel Urinary Biomarkers of Acute Kidney Injury in Vancomycin-Treated Rats.

Rhodes NJ, Prozialeck WC, Lodise TP, Venkatesan N, O'Donnell JN, Pais G, Cluff C, Lamar PC, Neely MN, Gulati A, Scheetz MH.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5742-51. doi: 10.1128/AAC.00591-16. Print 2016 Oct. Erratum in: Antimicrob Agents Chemother. 2017 Mar 24;61(4):.

17.

Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat.

Prozialeck WC, VanDreel A, Ackerman CD, Stock I, Papaeliou A, Yasmine C, Wilson K, Lamar PC, Sears VL, Gasiorowski JZ, DiNovo KM, Vaidya VS, Edwards JR.

Biometals. 2016 Feb;29(1):131-46. doi: 10.1007/s10534-015-9903-3. Epub 2015 Dec 29.

18.

Effects of Maternal Exposure to Cadmium Oxide Nanoparticles During Pregnancy on Maternal and Offspring Kidney Injury Markers Using a Murine Model.

Blum JL, Edwards JR, Prozialeck WC, Xiong JQ, Zelikoff JT.

J Toxicol Environ Health A. 2015;78(12):711-24. doi: 10.1080/15287394.2015.1026622.

19.

Pharmacology of kratom: an emerging botanical agent with stimulant, analgesic and opioid-like effects.

Prozialeck WC, Jivan JK, Andurkar SV.

J Am Osteopath Assoc. 2012 Dec;112(12):792-9. Review.

PMID:
23212430
20.

Effects of cadmium on the sub-cellular localization of β-catenin and β-catenin-regulated gene expression in NRK-52E cells.

Edwards JR, Kolman K, Lamar PC, Chandar N, Fay MJ, Prozialeck WC.

Biometals. 2013 Feb;26(1):33-42. doi: 10.1007/s10534-012-9592-0. Epub 2012 Oct 19.

PMID:
23080431
21.

Mechanisms of cadmium-induced proximal tubule injury: new insights with implications for biomonitoring and therapeutic interventions.

Prozialeck WC, Edwards JR.

J Pharmacol Exp Ther. 2012 Oct;343(1):2-12. doi: 10.1124/jpet.110.166769. Epub 2012 Jun 5. Review.

22.

Genistein induces estrogen-like effects in ovariectomized rats but fails to increase cardiac GLUT4 and oxidative stress.

Al-Nakkash L, Markus B, Batia L, Prozialeck WC, Broderick TL.

J Med Food. 2010 Dec;13(6):1369-75. doi: 10.1089/jmf.2009.0271. Epub 2010 Oct 18.

23.

Early biomarkers of cadmium exposure and nephrotoxicity.

Prozialeck WC, Edwards JR.

Biometals. 2010 Oct;23(5):793-809. doi: 10.1007/s10534-010-9288-2. Epub 2010 Jan 27. Review.

PMID:
20107869
24.

Effects of acute and 2-day genistein treatment on cardiac function and ischemic tolerance in ovariectomized rats.

Al-Nakkash L, Markus B, Bowden K, Batia LM, Prozialeck WC, Broderick TL.

Gend Med. 2009 Sep;6(3):488-97. doi: 10.1016/j.genm.2009.09.004.

PMID:
19850245
25.

A rapid urine test for early detection of kidney injury.

Vaidya VS, Ford GM, Waikar SS, Wang Y, Clement MB, Ramirez V, Glaab WE, Troth SP, Sistare FD, Prozialeck WC, Edwards JR, Bobadilla NA, Mefferd SC, Bonventre JV.

Kidney Int. 2009 Jul;76(1):108-14. doi: 10.1038/ki.2009.96. Epub 2009 Apr 22.

26.

Preclinical evaluation of novel urinary biomarkers of cadmium nephrotoxicity.

Prozialeck WC, Edwards JR, Vaidya VS, Bonventre JV.

Toxicol Appl Pharmacol. 2009 Aug 1;238(3):301-5. doi: 10.1016/j.taap.2009.01.012. Epub 2009 Feb 6.

27.

Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury.

Prozialeck WC, Edwards JR, Lamar PC, Liu J, Vaidya VS, Bonventre JV.

Toxicol Appl Pharmacol. 2009 Aug 1;238(3):306-14. doi: 10.1016/j.taap.2009.01.016. Epub 2009 Jan 31.

28.

Toxicology and Applied Pharmacology. Foreword.

Prozialeck WC.

Toxicol Appl Pharmacol. 2009 Aug 1;238(3):191. doi: 10.1016/j.taap.2009.03.016. Epub 2009 Mar 31. No abstract available.

PMID:
19344734
29.

Cadmium, diabetes and chronic kidney disease.

Edwards JR, Prozialeck WC.

Toxicol Appl Pharmacol. 2009 Aug 1;238(3):289-93. doi: 10.1016/j.taap.2009.03.007. Epub 2009 Mar 24. Review.

30.

Culture drives research funding.

Prozialeck WC.

J Am Osteopath Assoc. 2008 Jul;108(7):353. No abstract available.

PMID:
18648033
31.

Direct antiangiogenic actions of cadmium on human vascular endothelial cells.

Woods JM, Leone M, Klosowska K, Lamar PC, Shaknovsky TJ, Prozialeck WC.

Toxicol In Vitro. 2008 Apr;22(3):643-51. doi: 10.1016/j.tiv.2007.12.009. Epub 2007 Dec 28.

32.

The vascular system as a target of metal toxicity.

Prozialeck WC, Edwards JR, Nebert DW, Woods JM, Barchowsky A, Atchison WD.

Toxicol Sci. 2008 Apr;102(2):207-18. Epub 2007 Oct 18. Review.

33.

Kidney injury molecule-1 is an early biomarker of cadmium nephrotoxicity.

Prozialeck WC, Vaidya VS, Liu J, Waalkes MP, Edwards JR, Lamar PC, Bernard AM, Dumont X, Bonventre JV.

Kidney Int. 2007 Oct;72(8):985-93. Epub 2007 Aug 8.

34.
35.

Cell adhesion molecules in chemically-induced renal injury.

Prozialeck WC, Edwards JR.

Pharmacol Ther. 2007 Apr;114(1):74-93. Epub 2007 Jan 23. Review.

36.

Evaluation of the barrier properties of a commercially available renal epithelial cell system.

Prozialeck WC, Edwards JR, Lamar PC.

Toxicol In Vitro. 2007 Apr;21(3):533. Epub 2006 Oct 24. No abstract available.

PMID:
17175132
37.

Addressing substance abuse in medical school curricula.

Prozialeck WC.

J Am Osteopath Assoc. 2006 Jul;106(7):425-6; author reply 426. No abstract available.

PMID:
16912344
38.

The vascular endothelium as a target of cadmium toxicity.

Prozialeck WC, Edwards JR, Woods JM.

Life Sci. 2006 Sep 13;79(16):1493-506. Epub 2006 May 17. Review.

PMID:
16765992
39.

Epithelial barrier characteristics and expression of cell adhesion molecules in proximal tubule-derived cell lines commonly used for in vitro toxicity studies.

Prozialeck WC, Edwards JR, Lamar PC, Smith CS.

Toxicol In Vitro. 2006 Sep;20(6):942-53. Epub 2006 Jan 4.

PMID:
16387471
40.

P53 and beta-catenin activity during estrogen treatment of osteoblasts.

Chandar N, Saluja R, Lamar PC, Kolman K, Prozialeck WC.

Cancer Cell Int. 2005 Jul 29;5:24.

41.
42.

Characteristics of the courses that best predict COMLEX-USA level 1 performance.

Sefcik DJ, Prozialeck WC, O'Hare TH.

J Am Osteopath Assoc. 2003 Oct;103(10):491-4. No abstract available.

PMID:
14620085
43.
44.

Cadmium alters the localization of N-cadherin, E-cadherin, and beta-catenin in the proximal tubule epithelium.

Prozialeck WC, Lamar PC, Lynch SM.

Toxicol Appl Pharmacol. 2003 Jun 15;189(3):180-95. Erratum in: Toxicol Appl Pharmacol. 2003 Dec 15;193(3):394.

PMID:
12791303
45.

Effects of cadmium on E-cadherin and VE-cadherin in mouse lung.

Pearson CA, Lamar PC, Prozialeck WC.

Life Sci. 2003 Jan 31;72(11):1303-20.

PMID:
12570930
46.

Cadherins and NCAM as potential targets in metal toxicity.

Prozialeck WC, Grunwald GB, Dey PM, Reuhl KR, Parrish AR.

Toxicol Appl Pharmacol. 2002 Aug 1;182(3):255-65. Review.

PMID:
12183105
47.

Chlamydia trachomatis disrupts N-cadherin-dependent cell-cell junctions and sequesters beta-catenin in human cervical epithelial cells.

Prozialeck WC, Fay MJ, Lamar PC, Pearson CA, Sigar I, Ramsey KH.

Infect Immun. 2002 May;70(5):2605-13.

48.

Research in action: a summary of the 2001 American Osteopathic Association Research Conference.

Prozialeck WC.

J Am Osteopath Assoc. 2002 Mar;102(3):117-9. No abstract available.

PMID:
11926688
49.

Effect of a short-term in vitro exposure to the marine toxin domoic acid on viability, tumor necrosis factor-alpha, matrix metalloproteinase-9 and superoxide anion release by rat neonatal microglia.

Mayer AM, Hall M, Fay MJ, Lamar P, Pearson C, Prozialeck WC, Lehmann VK, Jacobson PB, Romanic AM, Uz T, Manev H.

BMC Pharmacol. 2001;1:7. Epub 2001 Oct 2.

50.

E-Cadherin, beta -Catenin and cadmium carcinogenesis.

Pearson CA, Prozialeck WC.

Med Hypotheses. 2001 May;56(5):573-81.

PMID:
11388771

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