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Items: 20


Memory inflation following adenoviral vaccination depends on IL-21.

Gordon CL, Hutchings CL, Highton AJ, Colston JM, Provine NM, Klenerman P.

Vaccine. 2018 Nov 12;36(46):7011-7016. doi: 10.1016/j.vaccine.2018.09.061. Epub 2018 Sep 29.


Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy.

Badamchi-Zadeh A, Moynihan KD, Larocca RA, Aid M, Provine NM, Iampietro MJ, Kinnear E, Penaloza-MacMaster P, Abbink P, Blass E, Tregoning JS, Irvine DJ, Barouch DH.

J Immunol. 2018 Nov 1;201(9):2744-2752. doi: 10.4049/jimmunol.1800885. Epub 2018 Sep 24.


Insights Into Mucosal-Associated Invariant T Cell Biology From Studies of Invariant Natural Killer T Cells.

Garner LC, Klenerman P, Provine NM.

Front Immunol. 2018 Jun 28;9:1478. doi: 10.3389/fimmu.2018.01478. eCollection 2018. Review.


Unique and Common Features of Innate-Like Human Vδ2+ γδT Cells and Mucosal-Associated Invariant T Cells.

Provine NM, Binder B, FitzPatrick MEB, Schuch A, Garner LC, Williamson KD, van Wilgenburg B, Thimme R, Klenerman P, Hofmann M.

Front Immunol. 2018 Apr 23;9:756. doi: 10.3389/fimmu.2018.00756. eCollection 2018.


Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors.

Iampietro MJ, Larocca RA, Provine NM, Abbink P, Kang ZH, Bricault CA, Barouch DH.

J Virol. 2018 May 14;92(11). pii: e00159-18. doi: 10.1128/JVI.00159-18. Print 2018 Jun 1.


Novel Concepts for HIV Vaccine Vector Design.

Alayo QA, Provine NM, Penaloza-MacMaster P.

mSphere. 2017 Dec 6;2(6). pii: e00415-17. doi: 10.1128/mSphere.00415-17. eCollection 2017 Nov-Dec. Review.


Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4+ T cell responses that impair CD8+ T cell function.

Larocca RA, Provine NM, Aid M, Iampietro MJ, Borducchi EN, Badamchi-Zadeh A, Abbink P, Ng'ang'a D, Bricault CA, Blass E, Penaloza-MacMaster P, Stephenson KE, Barouch DH.

Sci Immunol. 2016 Nov;1(5). pii: eaaf7643. doi: 10.1126/sciimmunol.aaf7643. Epub 2016 Nov 4.


Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens.

Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim M, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, Fuhrmann G, Lilja AE, Monath T, Mangeat B, Pinschewer DD, Barouch DH.

Vaccine. 2017 Jan 3;35(1):1-9. doi: 10.1016/j.vaccine.2016.11.063. Epub 2016 Nov 26.


Inhibitory receptor expression on memory CD8 T cells following Ad vector immunization.

Penaloza-MacMaster P, Alayo QA, Ra J, Provine NM, Larocca R, Lee B, Barouch DH.

Vaccine. 2016 Sep 22;34(41):4955-4963. doi: 10.1016/j.vaccine.2016.08.048. Epub 2016 Aug 24.


Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells.

Provine NM, Larocca RA, Aid M, Penaloza-MacMaster P, Badamchi-Zadeh A, Borducchi EN, Yates KB, Abbink P, Kirilova M, Ng'ang'a D, Bramson J, Haining WN, Barouch DH.

J Immunol. 2016 Sep 1;197(5):1809-22. doi: 10.4049/jimmunol.1600591. Epub 2016 Jul 22.


Transient CD4+ T Cell Depletion Results in Delayed Development of Functional Vaccine-Elicited Antibody Responses.

Provine NM, Badamchi-Zadeh A, Bricault CA, Penaloza-MacMaster P, Larocca RA, Borducchi EN, Seaman MS, Barouch DH.

J Virol. 2016 Apr 14;90(9):4278-4288. doi: 10.1128/JVI.00039-16. Print 2016 May.


CD4 T Cell Depletion Substantially Augments the Rescue Potential of PD-L1 Blockade for Deeply Exhausted CD8 T Cells.

Penaloza-MacMaster P, Provine NM, Blass E, Barouch DH.

J Immunol. 2015 Aug 1;195(3):1054-63. doi: 10.4049/jimmunol.1403237. Epub 2015 Jun 26.


Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection.

Penaloza-MacMaster P, Barber DL, Wherry EJ, Provine NM, Teigler JE, Parenteau L, Blackmore S, Borducchi EN, Larocca RA, Yates KB, Shen H, Haining WN, Sommerstein R, Pinschewer DD, Ahmed R, Barouch DH.

Science. 2015 Jan 16;347(6219):278-82. doi: 10.1126/science.aaa2148.


Hexon hypervariable region-modified adenovirus type 5 (Ad5) vectors display reduced hepatotoxicity but induce T lymphocyte phenotypes similar to Ad5 vectors.

Teigler JE, Penaloza-MacMaster P, Obeng R, Provine NM, Larocca RA, Borducchi EN, Barouch DH.

Clin Vaccine Immunol. 2014 Aug;21(8):1137-44. doi: 10.1128/CVI.00207-14. Epub 2014 Jun 18.


Longitudinal requirement for CD4+ T cell help for adenovirus vector-elicited CD8+ T cell responses.

Provine NM, Larocca RA, Penaloza-MacMaster P, Borducchi EN, McNally A, Parenteau LR, Kaufman DR, Barouch DH.

J Immunol. 2014 Jun 1;192(11):5214-25. doi: 10.4049/jimmunol.1302806. Epub 2014 Apr 28.


Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens.

Penaloza-MacMaster P, Teigler JE, Obeng RC, Kang ZH, Provine NM, Parenteau L, Blackmore S, Ra J, Borducchi EN, Barouch DH.

J Virol. 2014 Jun;88(11):6243-54. doi: 10.1128/JVI.00406-14. Epub 2014 Mar 19.


An attenuated Listeria monocytogenes vector primes more potent simian immunodeficiency virus-specific mucosal immunity than DNA vaccines in mice.

Im EJ, Borducchi EN, Provine NM, McNally AG, Li S, Frankel FR, Barouch DH.

J Virol. 2013 Apr;87(8):4751-5. doi: 10.1128/JVI.03085-12. Epub 2013 Feb 6.


Alternative serotype adenovirus vaccine vectors elicit memory T cells with enhanced anamnestic capacity compared to Ad5 vectors.

Penaloza-MacMaster P, Provine NM, Ra J, Borducchi EN, McNally A, Simmons NL, Iampietro MJ, Barouch DH.

J Virol. 2013 Feb;87(3):1373-84. doi: 10.1128/JVI.02058-12. Epub 2012 Nov 14.

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