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Items: 1 to 50 of 160

1.

Reply to Piquereau and Perros, and to Pullamsetti and de Jesus Perez.

Kurakula K, Boucherat O, Van der Feen DE, Bogaard HJ, Kulikowski E, Bartelds B, Provencher S, Berger RMF, Bonnet S, Goumans MJ.

Am J Respir Crit Care Med. 2019 Aug 16. doi: 10.1164/rccm.201905-1078LE. [Epub ahead of print] No abstract available.

PMID:
31419387
2.

Extended Anticoagulation for VTE: A Systematic Review and Meta-Analysis.

Mai V, Guay CA, Perreault L, Bonnet S, Bertoletti L, Lacasse Y, Jardel S, Lega JC, Provencher S.

Chest. 2019 Jun;155(6):1199-1216. doi: 10.1016/j.chest.2019.02.402.

PMID:
31174635
3.

Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.

Ranchoux B, Nadeau V, Bourgeois A, Provencher S, Tremblay É, Omura J, Coté N, Abu-Alhayja'a R, Dumais V, Nachbar RT, Tastet L, Dahou A, Breuils-Bonnet S, Marette A, Pibarot P, Dupuis J, Paulin R, Boucherat O, Archer SL, Bonnet S, Potus F.

Circ Res. 2019 Aug 2;125(4):449-466. doi: 10.1161/CIRCRESAHA.118.314555. Epub 2019 Jun 3.

PMID:
31154939
4.

Inhibition of CHK 1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension.

Bourgeois A, Bonnet S, Breuils-Bonnet S, Habbout K, Paradis R, Tremblay E, Lampron MC, Orcholski ME, Potus F, Bertero T, Peterlini T, Chan SY, Norris KA, Paulin R, Provencher S, Boucherat O.

Arterioscler Thromb Vasc Biol. 2019 Aug;39(8):1667-1681. doi: 10.1161/ATVBAHA.119.312537. Epub 2019 May 16.

PMID:
31092016
5.

Multicenter Preclinical Validation of BET Inhibition for the Treatment of Pulmonary Arterial Hypertension.

Van der Feen DE, Kurakula K, Tremblay E, Boucherat O, Bossers GP, Szulcek R, Bourgeois A, Lampron MC, Habbout K, Martineau S, Paulin R, Kulikowski E, Jahagirdar R, Schalij I, Bogaard HJ, Bartelds B, Provencher S, Berger RMF, Bonnet S, Goumans MJ.

Am J Respir Crit Care Med. 2019 May 1. doi: 10.1164/rccm.201812-2275OC. [Epub ahead of print]

PMID:
31042405
6.

Extended anticoagulation for the secondary prevention of venous thromboembolic events: An updated network meta-analysis.

Mai V, Bertoletti L, Cucherat M, Jardel S, Grange C, Provencher S, Lega JC.

PLoS One. 2019 Apr 1;14(4):e0214134. doi: 10.1371/journal.pone.0214134. eCollection 2019.

7.

Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: a UK cohort study analysis.

Sofianopoulou E, Kaptoge S, Gräf S, Hadinnapola C, Treacy CM, Church C, Coghlan G, Gibbs JSR, Haimel M, Howard LS, Johnson M, Kiely DG, Lawrie A, Lordan J, MacKenzie Ross RV, Martin JM, Moledina S, Newnham M, Peacock AJ, Price LC, Rhodes CJ, Suntharalingam J, Swietlik EM, Toshner MR, Wharton J, Wilkins MR, Wort SJ, Pepke-Zaba J, Condliffe R, Corris PA, Di Angelantonio E, Provencher S, Morrell NW.

Eur Respir J. 2019 May 30;53(5). pii: 1801429. doi: 10.1183/13993003.01429-2018. Print 2019 May.

PMID:
30923185
8.

Interatrial shunting for heart failure: current evidence and future perspectives.

Guimaraes L, Lindenfeld J, Sandoval J, Bayés-Genis A, Bernier M, Provencher S, Rodés-Cabau J.

EuroIntervention. 2019 Jun 20;15(2):164-171. doi: 10.4244/EIJ-D-18-01211.

9.

Treatment of idiopathic inflammatory myositis associated interstitial lung disease: A systematic review and meta-analysis.

Barba T, Fort R, Cottin V, Provencher S, Durieu I, Jardel S, Hot A, Reynaud Q, Lega JC.

Autoimmun Rev. 2019 Feb;18(2):113-122. doi: 10.1016/j.autrev.2018.07.013. Epub 2018 Dec 17.

PMID:
30572131
10.

Enhanced Pulmonary Artery Radiodensity in Pulmonary Arterial Hypertension: A Sign of Early Calcification?

Tanguay VF, Babin C, Giardetti G, Sohier-Poirier C, Ménard-Cholette V, Ranchoux B, Ruffenach G, Montani D, Bonnet S, Provencher S.

Am J Respir Crit Care Med. 2019 Mar 15;199(6):799-802. doi: 10.1164/rccm.201806-1027LE. No abstract available.

PMID:
30571924
11.

TAKling GDF-15 and skeletal muscle atrophy in pulmonary hypertension: are we there yet?

Lai YC, Provencher S, Goncharova EA.

Thorax. 2019 Feb;74(2):103-105. doi: 10.1136/thoraxjnl-2018-212680. Epub 2018 Dec 15. No abstract available.

PMID:
30554140
12.

Pulmonary hypertension in chronic lung disease and hypoxia.

Nathan SD, Barbera JA, Gaine SP, Harari S, Martinez FJ, Olschewski H, Olsson KM, Peacock AJ, Pepke-Zaba J, Provencher S, Weissmann N, Seeger W.

Eur Respir J. 2019 Jan 24;53(1). pii: 1801914. doi: 10.1183/13993003.01914-2018. Print 2019 Jan.

13.

Optimizing Lung Collapse With a Bronchial Blocker: It's Not What You Use, but How You Use It, Part II.

Bussières JS, Moreault O, Couture EJ, Provencher S.

J Cardiothorac Vasc Anesth. 2019 Jan;33(1):255. doi: 10.1053/j.jvca.2018.09.025. Epub 2018 Sep 28. No abstract available.

PMID:
30377052
14.

Pulmonary hypertension-targeted therapies in heart failure: A systematic review and meta-analysis.

Guay CA, Morin-Thibault LV, Bonnet S, Lacasse Y, Lambert C, Lega JC, Provencher S.

PLoS One. 2018 Oct 11;13(10):e0204610. doi: 10.1371/journal.pone.0204610. eCollection 2018.

15.

Management of Severe Pulmonary Hypertensive Disease for Surgical and Nonsurgical Procedures.

Couture EJ, Provencher S, Denault AY.

Int Anesthesiol Clin. 2018 Fall;56(4):e28-e55. doi: 10.1097/AIA.0000000000000202. Review. No abstract available.

PMID:
30204604
16.

Leading the Charge: Achievement of National Accreditation for a Nurse Residency Program.

Brown Tyo M, Gundlach M, Brennan C, Esdale L, Knight A, Provencher S, Tardy K.

J Nurses Prof Dev. 2018 Sep/Oct;34(5):270-276. doi: 10.1097/NND.0000000000000476.

PMID:
30188480
17.

Interpreting risk reduction in clinical trials for pulmonary arterial hypertension.

Lajoie AC, Bonnet S, Lacasse Y, Lega JC, Provencher S.

Eur Respir Rev. 2018 May 15;27(148). pii: 180020. doi: 10.1183/16000617.0020-2018. Print 2018 Jun 30. Review.

18.

Outcomes following a negative computed tomography pulmonary angiography according to pulmonary embolism prevalence: a meta-analysis of the management outcome studies.

Belzile D, Jacquet S, Bertoletti L, Lacasse Y, Lambert C, Lega JC, Provencher S.

J Thromb Haemost. 2018 Jun;16(6):1107-1120. doi: 10.1111/jth.14021. Epub 2018 May 17.

PMID:
29645405
19.

Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research.

Provencher S, Archer SL, Ramirez FD, Hibbert B, Paulin R, Boucherat O, Lacasse Y, Bonnet S.

Circ Res. 2018 Mar 30;122(7):1021-1032. doi: 10.1161/CIRCRESAHA.117.312579. Review.

PMID:
29599278
20.

Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertension.

Adão R, Mendes-Ferreira P, Santos-Ribeiro D, Maia-Rocha C, Pimentel LD, Monteiro-Pinto C, Mulvaney EP, Reid HM, Kinsella BT, Potus F, Breuils-Bonnet S, Rademaker MT, Provencher S, Bonnet S, Leite-Moreira AF, Brás-Silva C.

Cardiovasc Res. 2018 Jul 1;114(8):1165-1177. doi: 10.1093/cvr/cvy076.

PMID:
29584808
21.

Effect of position and positive pressure ventilation on functional residual capacity in morbidly obese patients: a randomized trial.

Couture EJ, Provencher S, Somma J, Lellouche F, Marceau S, Bussières JS.

Can J Anaesth. 2018 May;65(5):522-528. doi: 10.1007/s12630-018-1050-1. Epub 2018 Jan 18.

PMID:
29435810
22.

Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.

Boucherat O, Peterlini T, Bourgeois A, Nadeau V, Breuils-Bonnet S, Boilet-Molez S, Potus F, Meloche J, Chabot S, Lambert C, Tremblay E, Chae YC, Altieri DC, Sutendra G, Michelakis ED, Paulin R, Provencher S, Bonnet S.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):90-103. doi: 10.1164/rccm.201708-1751OC.

PMID:
29394093
23.

Pulmonary micro-tumor emboli resulting in paradoxical emboli: a case report.

Morin-Thibault LV, Wiseman D, Fortin M, Couture C, Provencher S.

Pulm Circ. 2018 Apr-Jun;8(2):2045893218754853. doi: 10.1177/2045893218754853. Epub 2018 Jan 8.

24.

FOXM1 promotes pulmonary artery smooth muscle cell expansion in pulmonary arterial hypertension.

Bourgeois A, Lambert C, Habbout K, Ranchoux B, Paquet-Marceau S, Trinh I, Breuils-Bonnet S, Paradis R, Nadeau V, Paulin R, Provencher S, Bonnet S, Boucherat O.

J Mol Med (Berl). 2018 Feb;96(2):223-235. doi: 10.1007/s00109-017-1619-0. Epub 2017 Dec 30.

PMID:
29290032
25.

Identity crisis in pulmonary arterial hypertension.

Ruffenach G, Bonnet S, Rousseaux S, Khochbin S, Provencher S, Perros F.

Pulm Circ. 2018 Jan-Mar;8(1):2045893217746054. doi: 10.1177/2045893217746054.

26.

Trial Duration and Risk Reduction in Combination Therapy Trials for Pulmonary Arterial Hypertension: A Systematic Review.

Lajoie AC, Guay CA, Lega JC, Lauzière G, Simard S, Lambert C, Lacasse Y, Bonnet S, Provencher S.

Chest. 2018 May;153(5):1142-1152. doi: 10.1016/j.chest.2017.11.014. Epub 2017 Nov 23.

PMID:
29175359
27.

Loss of SMAD3 Promotes Vascular Remodeling in Pulmonary Arterial Hypertension via MRTF Disinhibition.

Zabini D, Granton E, Hu Y, Miranda MZ, Weichelt U, Breuils Bonnet S, Bonnet S, Morrell NW, Connelly KA, Provencher S, Ghanim B, Klepetko W, Olschewski A, Kapus A, Kuebler WM.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):244-260. doi: 10.1164/rccm.201702-0386OC. Erratum in: Am J Respir Crit Care Med. 2019 Apr 1;199(7):932.

PMID:
29095649
28.

Dual ETA/ETB blockade with macitentan improves both vascular remodeling and angiogenesis in pulmonary arterial hypertension.

Nadeau V, Potus F, Boucherat O, Paradis R, Tremblay E, Iglarz M, Paulin R, Bonnet S, Provencher S.

Pulm Circ. 2018 Jan-Mar;8(1):2045893217741429. doi: 10.1177/2045893217741429. Epub 2017 Oct 24.

29.

Compromised Cerebrovascular Regulation and Cerebral Oxygenation in Pulmonary Arterial Hypertension.

Malenfant S, Brassard P, Paquette M, Le Blanc O, Chouinard A, Nadeau V, Allan PD, Tzeng YC, Simard S, Bonnet S, Provencher S.

J Am Heart Assoc. 2017 Oct 12;6(10). pii: e006126. doi: 10.1161/JAHA.117.006126.

30.

Therapeutic Value of ASK1 Inhibition in Pulmonary Arterial Hypertension.

Boucherat O, Provencher S, Bonnet S.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):284-286. doi: 10.1164/rccm.201708-1767ED. No abstract available.

PMID:
28930485
31.

HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension.

Boucherat O, Chabot S, Paulin R, Trinh I, Bourgeois A, Potus F, Lampron MC, Lambert C, Breuils-Bonnet S, Nadeau V, Paradis R, Goncharova EA, Provencher S, Bonnet S.

Sci Rep. 2017 Jul 3;7(1):4546. doi: 10.1038/s41598-017-04874-4.

32.

Clinical trial research in focus: improving drug development and trial design in pulmonary arterial hypertension.

Lajoie AC, Bonnet S, Provencher S.

Lancet Respir Med. 2017 Jul;5(7):544-546. doi: 10.1016/S2213-2600(17)30223-0. No abstract available.

PMID:
28664855
33.

Combination therapy in pulmonary arterial hypertension: recent accomplishments and future challenges.

Lajoie AC, Bonnet S, Provencher S.

Pulm Circ. 2017 Apr-Jun;7(2):312-325. doi: 10.1177/2045893217710639. Epub 2017 May 30.

34.

The cancer theory of pulmonary arterial hypertension.

Boucherat O, Vitry G, Trinh I, Paulin R, Provencher S, Bonnet S.

Pulm Circ. 2017 Apr-Jun;7(2):285-299. doi: 10.1177/2045893217701438. Epub 2017 Mar 27.

35.

Implication of Inflammation and Epigenetic Readers in Coronary Artery Remodeling in Patients With Pulmonary Arterial Hypertension.

Meloche J, Lampron MC, Nadeau V, Maltais M, Potus F, Lambert C, Tremblay E, Vitry G, Breuils-Bonnet S, Boucherat O, Charbonneau E, Provencher S, Paulin R, Bonnet S.

Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1513-1523. doi: 10.1161/ATVBAHA.117.309156. Epub 2017 May 4.

PMID:
28473439
36.

Use of β-Blockers in Pulmonary Hypertension.

Perros F, de Man FS, Bogaard HJ, Antigny F, Simonneau G, Bonnet S, Provencher S, Galiè N, Humbert M.

Circ Heart Fail. 2017 Apr;10(4). pii: e003703. doi: 10.1161/CIRCHEARTFAILURE.116.003703. Review.

PMID:
28364092
37.

Molecular imaging of the human pulmonary vascular endothelium in pulmonary hypertension: a phase II safety and proof of principle trial.

Harel F, Langleben D, Provencher S, Fournier A, Finnerty V, Nguyen QT, Letourneau M, Levac X, Abikhzer G, Guimond J, Mansour A, Guertin MC, Dupuis J.

Eur J Nucl Med Mol Imaging. 2017 Jul;44(7):1136-1144. doi: 10.1007/s00259-017-3655-y. Epub 2017 Feb 24.

38.

Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension.

Bonnet S, Provencher S, Guignabert C, Perros F, Boucherat O, Schermuly RT, Hassoun PM, Rabinovitch M, Nicolls MR, Humbert M.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):583-595. doi: 10.1164/rccm.201607-1515PP. Review. No abstract available.

39.

MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.

Hong Z, Chen KH, DasGupta A, Potus F, Dunham-Snary K, Bonnet S, Tian L, Fu J, Breuils-Bonnet S, Provencher S, Wu D, Mewburn J, Ormiston ML, Archer SL.

Am J Respir Crit Care Med. 2017 Feb 15;195(4):515-529. doi: 10.1164/rccm.201604-0814OC.

40.

High Oxygen Delivery to Preserve Exercise Capacity in Patients with Idiopathic Pulmonary Fibrosis Treated with Nintedanib. Methodology of the HOPE-IPF Study.

Ryerson CJ, Camp PG, Eves ND, Schaeffer M, Syed N, Dhillon S, Jensen D, Maltais F, O'Donnell DE, Raghavan N, Roman M, Stickland MK, Assayag D, Bourbeau J, Dion G, Fell CD, Hambly N, Johannson KA, Kalluri M, Khalil N, Kolb M, Manganas H, Morán-Mendoza O, Provencher S, Ramesh W, Rolf JD, Wilcox PG, Guenette JA.

Ann Am Thorac Soc. 2016 Sep;13(9):1640-7. doi: 10.1513/AnnalsATS.201604-267OC.

PMID:
27348402
41.

DNA Damage and Pulmonary Hypertension.

Ranchoux B, Meloche J, Paulin R, Boucherat O, Provencher S, Bonnet S.

Int J Mol Sci. 2016 Jun 22;17(6). pii: E990. doi: 10.3390/ijms17060990. Review.

42.

Shear Stress Maladaptation in Pulmonary Arterial Hypertension. An Ageless Concept.

Bonnet S, Provencher S.

Am J Respir Crit Care Med. 2016 Jun 15;193(12):1331-2. doi: 10.1164/rccm.201601-0113ED. No abstract available.

PMID:
27304240
43.

Role for Runt-related Transcription Factor 2 in Proliferative and Calcified Vascular Lesions in Pulmonary Arterial Hypertension.

Ruffenach G, Chabot S, Tanguay VF, Courboulin A, Boucherat O, Potus F, Meloche J, Pflieger A, Breuils-Bonnet S, Nadeau V, Paradis R, Tremblay E, Girerd B, Hautefort A, Montani D, Fadel E, Dorfmuller P, Humbert M, Perros F, Paulin R, Provencher S, Bonnet S.

Am J Respir Crit Care Med. 2016 Nov 15;194(10):1273-1285.

PMID:
27149112
44.

Combination therapy versus monotherapy for pulmonary arterial hypertension: a meta-analysis.

Lajoie AC, Lauzière G, Lega JC, Lacasse Y, Martin S, Simard S, Bonnet S, Provencher S.

Lancet Respir Med. 2016 Apr;4(4):291-305. doi: 10.1016/S2213-2600(16)00027-8. Epub 2016 Feb 27. Review. Erratum in: Lancet Respir Med. 2016 Jun;4(6):e34.

PMID:
26935844
45.

Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension.

Antigny F, Hautefort A, Meloche J, Belacel-Ouari M, Manoury B, Rucker-Martin C, Péchoux C, Potus F, Nadeau V, Tremblay E, Ruffenach G, Bourgeois A, Dorfmüller P, Breuils-Bonnet S, Fadel E, Ranchoux B, Jourdon P, Girerd B, Montani D, Provencher S, Bonnet S, Simonneau G, Humbert M, Perros F.

Circulation. 2016 Apr 5;133(14):1371-85. doi: 10.1161/CIRCULATIONAHA.115.020951. Epub 2016 Feb 24.

PMID:
26912814
46.

Bridging Lung Development with Chronic Obstructive Pulmonary Disease. Relevance of Developmental Pathways in Chronic Obstructive Pulmonary Disease Pathogenesis.

Boucherat O, Morissette MC, Provencher S, Bonnet S, Maltais F.

Am J Respir Crit Care Med. 2016 Feb 15;193(4):362-75. doi: 10.1164/rccm.201508-1518PP. Review.

PMID:
26681127
47.

Potassium channels in pulmonary arterial hypertension.

Boucherat O, Chabot S, Antigny F, Perros F, Provencher S, Bonnet S.

Eur Respir J. 2015 Oct;46(4):1167-77. doi: 10.1183/13993003.00798-2015. Epub 2015 Sep 4. Review.

48.

Diagnostic yield of non-guided flexible bronchoscopy for peripheral pulmonary neoplasia.

Labbé C, Beaudoin S, Martel S, Delage A, Joubert P, Drapeau C, Provencher S.

Thorac Cancer. 2015 Jul;6(4):517-23. doi: 10.1111/1759-7714.12223. Epub 2015 Jan 22.

49.

Bromodomain-Containing Protein 4: The Epigenetic Origin of Pulmonary Arterial Hypertension.

Meloche J, Potus F, Vaillancourt M, Bourgeois A, Johnson I, Deschamps L, Chabot S, Ruffenach G, Henry S, Breuils-Bonnet S, Tremblay È, Nadeau V, Lambert C, Paradis R, Provencher S, Bonnet S.

Circ Res. 2015 Aug 28;117(6):525-35. doi: 10.1161/CIRCRESAHA.115.307004. Epub 2015 Jul 29.

PMID:
26224795
50.

Downregulation of MicroRNA-126 Contributes to the Failing Right Ventricle in Pulmonary Arterial Hypertension.

Potus F, Ruffenach G, Dahou A, Thebault C, Breuils-Bonnet S, Tremblay È, Nadeau V, Paradis R, Graydon C, Wong R, Johnson I, Paulin R, Lajoie AC, Perron J, Charbonneau E, Joubert P, Pibarot P, Michelakis ED, Provencher S, Bonnet S.

Circulation. 2015 Sep 8;132(10):932-43. doi: 10.1161/CIRCULATIONAHA.115.016382. Epub 2015 Jul 10.

PMID:
26162916

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