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Items: 13

1.

Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy.

Bellerose MM, Baek SH, Huang CC, Moss CE, Koh EI, Proulx MK, Smith CM, Baker RE, Lee JS, Eum S, Shin SJ, Cho SN, Murray M, Sassetti CM.

MBio. 2019 Jul 30;10(4). pii: e00663-19. doi: 10.1128/mBio.00663-19.

2.

Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N, Delano K, Da Silva I, Davis J, Gallo C, Gardner M, Golas AJ, Guinn KM, Kennedy S, Korn R, McConnell JA, Moss CE, Murphy KC, Nietupski RM, Papavinasasundaram KG, Pinkham JT, Pino PA, Proulx MK, Ruecker N, Song N, Thompson M, Trujillo C, Wakabayashi S, Wallach JB, Watson C, Ioerger TR, Lander ES, Hubbard BK, Serrano-Wu MH, Ehrt S, Fitzgerald M, Rubin EJ, Sassetti CM, Schnappinger D, Hung DT.

Nature. 2019 Jul;571(7763):72-78. doi: 10.1038/s41586-019-1315-z. Epub 2019 Jun 19.

PMID:
31217586
3.

Gain-of-Function Analysis Reveals Important Virulence Roles for the Yersinia pestis Type III Secretion System Effectors YopJ, YopT, and YpkA.

Palace SG, Proulx MK, Szabady RL, Goguen JD.

Infect Immun. 2018 Aug 22;86(9). pii: e00318-18. doi: 10.1128/IAI.00318-18. Print 2018 Sep.

4.

The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.

Ratner D, Orning MP, Proulx MK, Wang D, Gavrilin MA, Wewers MD, Alnemri ES, Johnson PF, Lee B, Mecsas J, Kayagaki N, Goguen JD, Lien E.

PLoS Pathog. 2016 Dec 2;12(12):e1006035. doi: 10.1371/journal.ppat.1006035. eCollection 2016 Dec.

5.

Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype.

Smith CM, Proulx MK, Olive AJ, Laddy D, Mishra BB, Moss C, Gutierrez NM, Bellerose MM, Barreira-Silva P, Phuah JY, Baker RE, Behar SM, Kornfeld H, Evans TG, Beamer G, Sassetti CM.

MBio. 2016 Sep 20;7(5). pii: e01516-16. doi: 10.1128/mBio.01516-16.

6.

Manipulation of interleukin-1β and interleukin-18 production by Yersinia pestis effectors YopJ and YopM and redundant impact on virulence.

Ratner D, Orning MP, Starheim KK, Marty-Roix R, Proulx MK, Goguen JD, Lien E.

J Biol Chem. 2016 Jul 29;291(31):16417. doi: 10.1074/jbc.A115.697698. No abstract available.

7.

Reply to Gelfand and Cleveland.

Proulx MK, Ellison RT 3rd, Goguen JD.

J Infect Dis. 2016 May 15;213(10):1671-2. No abstract available.

8.

Manipulation of Interleukin-1β and Interleukin-18 Production by Yersinia pestis Effectors YopJ and YopM and Redundant Impact on Virulence.

Ratner D, Orning MP, Starheim KK, Marty-Roix R, Proulx MK, Goguen JD, Lien E.

J Biol Chem. 2016 May 6;291(19):9894-905. doi: 10.1074/jbc.M115.697698. Epub 2016 Feb 16. Erratum in: J Biol Chem. 2016 Jul 29;291(31):16417.

9.

Reversion From Methicillin Susceptibility to Methicillin Resistance in Staphylococcus aureus During Treatment of Bacteremia.

Proulx MK, Palace SG, Gandra S, Torres B, Weir S, Stiles T, Ellison RT 3rd, Goguen JD.

J Infect Dis. 2016 Mar 15;213(6):1041-8. doi: 10.1093/infdis/jiv512. Epub 2015 Oct 26.

10.

Genome-wide mutant fitness profiling identifies nutritional requirements for optimal growth of Yersinia pestis in deep tissue.

Palace SG, Proulx MK, Lu S, Baker RE, Goguen JD.

MBio. 2014 Aug 19;5(4). pii: e01385-14. doi: 10.1128/mBio.01385-14.

11.

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

Weng D, Marty-Roix R, Ganesan S, Proulx MK, Vladimer GI, Kaiser WJ, Mocarski ES, Pouliot K, Chan FK, Kelliher MA, Harris PA, Bertin J, Gough PJ, Shayakhmetov DM, Goguen JD, Fitzgerald KA, Silverman N, Lien E.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7391-6. doi: 10.1073/pnas.1403477111. Epub 2014 May 5.

12.

The NLRP12 inflammasome recognizes Yersinia pestis.

Vladimer GI, Weng D, Paquette SW, Vanaja SK, Rathinam VA, Aune MH, Conlon JE, Burbage JJ, Proulx MK, Liu Q, Reed G, Mecsas JC, Iwakura Y, Bertin J, Goguen JD, Fitzgerald KA, Lien E.

Immunity. 2012 Jul 27;37(1):96-107. doi: 10.1016/j.immuni.2012.07.006. Erratum in: Immunity. 2012 Sep 21;37(3):588.

13.

Fibrin microthreads support mesenchymal stem cell growth while maintaining differentiation potential.

Proulx MK, Carey SP, Ditroia LM, Jones CM, Fakharzadeh M, Guyette JP, Clement AL, Orr RG, Rolle MW, Pins GD, Gaudette GR.

J Biomed Mater Res A. 2011 Feb;96(2):301-12. doi: 10.1002/jbm.a.32978.

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