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Peroxynitrite decomposition catalyst reduces vasopressin requirement in ovine MRSA sepsis.

Fujiwara O, Fukuda S, Lopez E, Zeng Y, Niimi Y, DeWitt DS, Herndon DN, Prough DS, Enkhbaatar P.

Intensive Care Med Exp. 2019 Sep 9;7(1):12. doi: 10.1186/s40635-019-0227-4.


MicroRNA profiling identifies a novel compound with antidepressant properties.

Sell SL, Boone DR, Weisz HA, Cardenas C, Willey HE, Bolding IJ, Micci MA, Falduto MT, Torres KEO, DeWitt DS, Prough DS, Hellmich HL.

PLoS One. 2019 Aug 23;14(8):e0221163. doi: 10.1371/journal.pone.0221163. eCollection 2019.


Surgical anatomy of the ovine sural nerve for facial nerve regeneration and reconstruction research.

Niimi Y, Fukuda S, Gilbert RS, Baljinnyam T, Niimi Y, Matsumine H, Liu K, Jacob S, Hawkins HK, Cox RA, Herndon DN, Prough DS, Enkhbaatar P.

Sci Rep. 2019 Jul 22;9(1):10564. doi: 10.1038/s41598-019-46661-3.


Population Kinetics of 0.9% Saline Distribution in Hemorrhaged Awake and Isoflurane-anesthetized Volunteers.

Nyberg J, Li H, Wessmark P, Winther V, Prough DS, Kinsky MP, Svensén CH.

Anesthesiology. 2019 Sep;131(3):501-511. doi: 10.1097/ALN.0000000000002816.


Cerebral Blood Flow and Blood Pressure: Dependent or Codependent?

DeWitt DS, Prough DS.

Crit Care Med. 2019 Jul;47(7):1007-1009. doi: 10.1097/CCM.0000000000003784. No abstract available.


Monophosphoryl Lipid A Attenuates Multiorgan Dysfunction During Post-Burn Pseudomonas Aeruginosa Pneumonia In Sheep.

Fukuda S, Ihara K, Bohannon JK, Hernandez A, Patil NK, Luan L, Stothers C, Stark R, Prough DS, Herndon DN, Sherwood ER, Enkhbaatar P.

Shock. 2019 Apr 26. doi: 10.1097/SHK.0000000000001364. [Epub ahead of print]


Club Cell Protein, CC10, Attenuates Acute Respiratory Distress Syndrome Induced by Smoke Inhalation.

Lopez E, Fujiwara O, Nelson C, Winn ME, Clayton RS, Cox RA, Hawkins HK, Andersen CR, Wade CE, Hariprakasha H, Prough DS, Pilon AL, Enkhbaatar P.

Shock. 2019 Apr 29. doi: 10.1097/SHK.0000000000001365. [Epub ahead of print]


Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries.

Rodriguez UA, Zeng Y, Parsley MA, Hawkins BE, Prough DS, DeWitt DS.

J Vis Exp. 2019 Apr 1;(146). doi: 10.3791/58792.


Traumatic brain injury induces long-lasting changes in immune and regenerative signaling.

Boone DR, Weisz HA, Willey HE, Torres KEO, Falduto MT, Sinha M, Spratt H, Bolding IJ, Johnson KM, Parsley MA, DeWitt DS, Prough DS, Hellmich HL.

PLoS One. 2019 Apr 3;14(4):e0214741. doi: 10.1371/journal.pone.0214741. eCollection 2019.


Finding the Hidden (Statistical) Platform.

Andersen CR, Hawkins BE, Prough DS.

Crit Care Med. 2019 Mar;47(3):480-483. doi: 10.1097/CCM.0000000000003611. No abstract available.


Surgical anatomy of ovine facial and hypoglossal nerves for facial nerve reconstruction and regeneration research: An experimental study in sheep.

Niimi Y, Matsumine H, Fukuda S, Salsbury JR, Niimi Y, Herndon DN, Prough DS, Enkhbaatar P.

Microsurgery. 2019 Jan 21. doi: 10.1002/micr.30405. [Epub ahead of print]


Modulation of Peroxynitrite Reduces Norepinephrine Requirements in Ovine MRSA Septic Shock.

Fukuda S, Ihara K, Andersen CR, Randolph AC, Nelson CL, Zeng Y, Kim J, DeWitt DS, Rojas JD, Koutrouvelis A, Herndon DN, Prough DS, Enkhbaatar P.

Shock. 2019 Nov;52(5):e92-e99. doi: 10.1097/SHK.0000000000001297.


Mild, moderate and severe: terminology implications for clinical and experimental traumatic brain injury.

Yamamoto S, Levin HS, Prough DS.

Curr Opin Neurol. 2018 Dec;31(6):672-680. doi: 10.1097/WCO.0000000000000624. Review.


Proteomic changes in traumatic brain injury: experimental approaches.

Sowers JL, Wu P, Zhang K, DeWitt DS, Prough DS.

Curr Opin Neurol. 2018 Dec;31(6):709-717. doi: 10.1097/WCO.0000000000000613. Review.


Publisher Correction: Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injury.

Boone DK, Weisz HA, Bi M, Falduto MT, Torres KEO, Willey HE, Volsko CM, Kumar AM, Micci MA, Dewitt DS, Prough DS, Hellmich HL.

Sci Rep. 2018 Oct 8;8(1):14994. doi: 10.1038/s41598-018-31991-5.


Accuracy and Precision of an Optoacoustic Prototype in Determining Endotracheal Tube Position in Children.

Volsko TA, Petrov Y, McNinch NL, Prough DS, Anderson CR, Bigham MT.

Respir Care. 2018 Dec;63(12):1463-1470. doi: 10.4187/respcare.06140. Epub 2018 Jul 31.


Adherence to Endotracheal Tube Depth Guidelines and Incidence of Malposition in Infants and Children.

Volsko TA, McNinch NL, Prough DS, Bigham MT.

Respir Care. 2018 Sep;63(9):1111-1117. doi: 10.4187/respcare.06024. Epub 2018 Jul 17.


Pre-Clinical Testing of Therapies for Traumatic Brain Injury.

DeWitt DS, Hawkins BE, Dixon CE, Kochanek PM, Armstead W, Bass CR, Bramlett HM, Buki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds SR, LaPlaca MC, Long JB, Meaney DF, Mondello S, Noble-Haeusslein LJ, Poloyac SM, Prough DS, Robertson CS, Saatman KE, Shultz SR, Shear DA, Smith DH, Valadka AB, VandeVord P, Zhang L.

J Neurotrauma. 2018 Dec 1;35(23):2737-2754. doi: 10.1089/neu.2018.5778. Epub 2018 Aug 30.


Is "Moderate" the Correct Adjective?

Yamamoto S, Levin HS, Robertson CS, Prough DS.

Crit Care Med. 2018 May;46(5):829-831. doi: 10.1097/CCM.0000000000003053. No abstract available.


Nano-Pulsed Laser Therapy Is Neuroprotective in a Rat Model of Blast-Induced Neurotrauma.

Esenaliev RO, Petrov IY, Petrov Y, Guptarak J, Boone DR, Mocciaro E, Weisz H, Parsley MA, Sell SL, Hellmich H, Ford JM, Pogue C, DeWitt D, Prough DS, Micci MA.

J Neurotrauma. 2018 Jul 1;35(13):1510-1522. doi: 10.1089/neu.2017.5249. Epub 2018 Apr 30.


Impact & Blast Traumatic Brain Injury: Implications for Therapy.

Yamamoto S, DeWitt DS, Prough DS.

Molecules. 2018 Jan 26;23(2). pii: E245. doi: 10.3390/molecules23020245. Review.


Effects of Mild Blast Traumatic Brain Injury on Cerebral Vascular, Histopathological, and Behavioral Outcomes in Rats.

Rodriguez UA, Zeng Y, Deyo D, Parsley MA, Hawkins BE, Prough DS, DeWitt DS.

J Neurotrauma. 2018 Jan 15;35(2):375-392. doi: 10.1089/neu.2017.5256. Epub 2017 Dec 20.


Effects of AAV-mediated knockdown of nNOS and GPx-1 gene expression in rat hippocampus after traumatic brain injury.

Boone DR, Leek JM, Falduto MT, Torres KEO, Sell SL, Parsley MA, Cowart JC, Uchida T, Micci MA, DeWitt DS, Prough DS, Hellmich HL.

PLoS One. 2017 Oct 10;12(10):e0185943. doi: 10.1371/journal.pone.0185943. eCollection 2017.


Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injury.

Boone DK, Weisz HA, Bi M, Falduto MT, Torres KEO, Willey HE, Volsko CM, Kumar AM, Micci MA, Dewitt DS, Prough DS, Hellmich HL.

Sci Rep. 2017 Jul 27;7(1):6645. doi: 10.1038/s41598-017-06341-6. Erratum in: Sci Rep. 2018 Oct 8;8(1):14994.


Delirium prevention: another piece of the puzzle.

Teegarden BM, Prough DS.

J Thorac Dis. 2016 Dec;8(12):E1614-E1616. doi: 10.21037/jtd.2016.12.27. No abstract available.


Persistent Behavioral Deficits in Rats after Parasagittal Fluid Percussion Injury.

Sell SL, Johnson K, DeWitt DS, Prough DS.

J Neurotrauma. 2017 Mar 1;34(5):1086-1096. doi: 10.1089/neu.2016.4616. Epub 2016 Oct 18.


Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant.

López-García I, Gerő D, Szczesny B, Szoleczky P, Olah G, Módis K, Zhang K, Gao J, Wu P, Sowers LC, DeWitt D, Prough DS, Szabo C.

Br J Pharmacol. 2018 Jan;175(2):284-300. doi: 10.1111/bph.13642. Epub 2016 Nov 15.


What to Do When Haloperidol Fails to Treat Agitated Delirium: Is Dexmedetomidine the Next Step?

Teegarden BM, Prough DS.

Crit Care Med. 2016 Jul;44(7):1426-8. doi: 10.1097/CCM.0000000000001803. No abstract available.


Delirium: Getting Back on Track.

Teegarden BM, Prough DS.

Crit Care Med. 2016 Jul;44(7):1265-6. doi: 10.1097/CCM.0000000000001945. No abstract available.


Reducing the Angst Associated With Withdrawal of Life-Sustaining Therapy.

Cohen MS, Prough DS.

Crit Care Med. 2016 Jun;44(6):1241-2. doi: 10.1097/CCM.0000000000001810. No abstract available.


Human Neural Stem Cell Transplantation-Mediated Alteration of Microglial/Macrophage Phenotypes after Traumatic Brain Injury.

Gao J, Grill RJ, Dunn TJ, Bedi S, Labastida JA, Hetz RA, Xue H, Thonhoff JR, DeWitt DS, Prough DS, Cox CS Jr, Wu P.

Cell Transplant. 2016 Oct;25(10):1863-1877. doi: 10.3727/096368916X691150.


Molecular Turbocharging Stem Cells to Improve Treatment of Experimental Spinal Cord Injury.

Wu P, Prough DS.

Crit Care Med. 2016 Mar;44(3):649-50. doi: 10.1097/CCM.0000000000001534. No abstract available.


Tau Oligomers Derived from Traumatic Brain Injury Cause Cognitive Impairment and Accelerate Onset of Pathology in Htau Mice.

Gerson J, Castillo-Carranza DL, Sengupta U, Bodani R, Prough DS, DeWitt DS, Hawkins BE, Kayed R.

J Neurotrauma. 2016 Nov 15;33(22):2034-2043. Epub 2016 Apr 22.


Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A.

Enkhbaatar P, Nelson C, Salsbury JR, Carmical JR, Torres KE, Herndon D, Prough DS, Luan L, Sherwood ER.

PLoS One. 2015 Dec 7;10(12):e0144345. doi: 10.1371/journal.pone.0144345. eCollection 2015.


Nebulized Epinephrine Limits Pulmonary Vascular Hyperpermeability to Water and Protein in Ovine With Burn and Smoke Inhalation Injury.

Lopez E, Fujiwara O, Lima-Lopez F, Suman OE, Mlcak RP, Hawkins HK, Cox RA, Herndon DN, Prough DS, Enkhbaatar P.

Crit Care Med. 2016 Feb;44(2):e89-96. doi: 10.1097/CCM.0000000000001349.


Measurement of Postreplicative DNA Metabolism and Damage in the Rodent Brain.

Patel JP, Sowers ML, Herring JL, Theruvathu JA, Emmett MR, Hawkins BE, Zhang K, DeWitt DS, Prough DS, Sowers LC.

Chem Res Toxicol. 2015 Dec 21;28(12):2352-63. doi: 10.1021/acs.chemrestox.5b00359. Epub 2015 Nov 24.


Pathway-focused PCR array profiling of enriched populations of laser capture microdissected hippocampal cells after traumatic brain injury.

Boone DR, Micci MA, Taglialatela IG, Hellmich JL, Weisz HA, Bi M, Prough DS, DeWitt DS, Hellmich HL.

PLoS One. 2015 May 27;10(5):e0127287. doi: 10.1371/journal.pone.0127287. eCollection 2015.


Optoacoustic detection of intra- and extracranial hematomas in rats after blast injury.

Petrov A, Wynne KE, Parsley MA, Petrov IY, Petrov Y, Ruppert KA, Prough DS, DeWitt DS, Esenaliev RO.

Photoacoustics. 2014 Apr 13;2(2):75-80. doi: 10.1016/j.pacs.2014.04.001. eCollection 2014 Jun.


Isoproternenol increases vascular volume expansion and urinary output after a large crystalloid bolus in healthy volunteers.

Asmussen S, Salter M, Prough DS, Kramer GC, Svensen C, Sheffield-Moore M, Kinsky MP.

Shock. 2014 Nov;42(5):407-14. doi: 10.1097/SHK.0000000000000233.


Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia.

Asmussen S, Ito H, Traber DL, Lee JW, Cox RA, Hawkins HK, McAuley DF, McKenna DH, Traber LD, Zhuo H, Wilson J, Herndon DN, Prough DS, Liu KD, Matthay MA, Enkhbaatar P.

Thorax. 2014 Sep;69(9):819-25. doi: 10.1136/thoraxjnl-2013-204980. Epub 2014 Jun 2.


Advantages and pitfalls of combining intravenous antithrombin with nebulized heparin and tissue plasminogen activator in acute respiratory distress syndrome.

Rehberg S, Yamamoto Y, Sousse LE, Jonkam C, Cox RA, Prough DS, Enkhbaatar P.

J Trauma Acute Care Surg. 2014 Jan;76(1):126-33. doi: 10.1097/TA.0b013e3182ab0785.


Traumatic brain injury in vivo and in vitro contributes to cerebral vascular dysfunction through impaired gap junction communication between vascular smooth muscle cells.

Yu GX, Mueller M, Hawkins BE, Mathew BP, Parsley MA, Vergara LA, Hellmich HL, Prough DS, Dewitt DS.

J Neurotrauma. 2014 Apr 15;31(8):739-48. doi: 10.1089/neu.2013.3187. Epub 2014 Jan 31.


Antithrombin attenuates vascular leakage via inhibiting neutrophil activation in acute lung injury.

Rehberg S, Yamamoto Y, Sousse LE, Jonkam C, Zhu Y, Traber LD, Cox RA, Prough DS, Traber DL, Enkhbaatar P.

Crit Care Med. 2013 Dec;41(12):e439-46. doi: 10.1097/CCM.0b013e318298ad3a.


Test driving levosimendan as the new "kidney protector": first impressions...

Gamilla-Crudo AK, Kadambi PV, Prough DS.

Crit Care Med. 2013 Oct;41(10):2445-6. doi: 10.1097/CCM.0b013e3182963fdc. No abstract available.


Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies.

Hawkins BE, Krishnamurthy S, Castillo-Carranza DL, Sengupta U, Prough DS, Jackson GR, DeWitt DS, Kayed R.

J Biol Chem. 2013 Jun 7;288(23):17042-50. doi: 10.1074/jbc.M113.472746. Epub 2013 Apr 30.


Monitoring the brain to save the kidneys.

Prough DS, Esenaliev R.

Crit Care Med. 2013 Feb;41(2):671-2. doi: 10.1097/CCM.0b013e318274247e. No abstract available.


Pathway analysis reveals common pro-survival mechanisms of metyrapone and carbenoxolone after traumatic brain injury.

Hellmich HL, Rojo DR, Micci MA, Sell SL, Boone DR, Crookshanks JM, DeWitt DS, Masel BE, Prough DS.

PLoS One. 2013;8(1):e53230. doi: 10.1371/journal.pone.0053230. Epub 2013 Jan 9.


Effects of trauma, hemorrhage and resuscitation in aged rats.

Hawkins BE, Cowart JC, Parsley MA, Capra BA, Eidson KA, Hellmich HL, Dewitt DS, Prough DS.

Brain Res. 2013 Feb 16;1496:28-35. doi: 10.1016/j.brainres.2012.12.027. Epub 2012 Dec 28.


'Professor Galveston' has departed. Obituary--Daniel Traber.

Prough DS, Enhkbaatar P, Szabo C.

Crit Care. 2012 Nov 8;16(6):169. doi: 10.1186/cc11810. No abstract available.


Traumatic brain injury-induced dysregulation of the circadian clock.

Boone DR, Sell SL, Micci MA, Crookshanks JM, Parsley M, Uchida T, Prough DS, DeWitt DS, Hellmich HL.

PLoS One. 2012;7(10):e46204. doi: 10.1371/journal.pone.0046204. Epub 2012 Oct 3.

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