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Items: 1 to 20 of 24


A lower affinity to cytosolic proteins reveals VDAC3 isoform-specific role in mitochondrial biology.

Queralt-Martín M, Bergdoll L, Teijido O, Munshi N, Jacobs D, Kuszak AJ, Protchenko O, Reina S, Magrì A, De Pinto V, Bezrukov SM, Abramson J, Rostovtseva TK.

J Gen Physiol. 2020 Feb 3;152(2). pii: e201912501. doi: 10.1085/jgp.201912501.


Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction?

Stoyanovsky DA, Tyurina YY, Shrivastava I, Bahar I, Tyurin VA, Protchenko O, Jadhav S, Bolevich SB, Kozlov AV, Vladimirov YA, Shvedova AA, Philpott CC, Bayir H, Kagan VE.

Free Radic Biol Med. 2019 Mar;133:153-161. doi: 10.1016/j.freeradbiomed.2018.09.008. Epub 2018 Sep 12. Review.


PCBP1 and NCOA4 regulate erythroid iron storage and heme biosynthesis.

Ryu MS, Zhang D, Protchenko O, Shakoury-Elizeh M, Philpott CC.

J Clin Invest. 2017 May 1;127(5):1786-1797. doi: 10.1172/JCI90519. Epub 2017 Apr 4.


Fungal physiology: Robbing the bank of haem iron.

Philpott CC, Protchenko O.

Nat Microbiol. 2016 Oct 26;1(11):16179. doi: 10.1038/nmicrobiol.2016.179. No abstract available.


α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease.

Rostovtseva TK, Gurnev PA, Protchenko O, Hoogerheide DP, Yap TL, Philpott CC, Lee JC, Bezrukov SM.

J Biol Chem. 2015 Jul 24;290(30):18467-77. doi: 10.1074/jbc.M115.641746. Epub 2015 Jun 8.


Heme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1.

Huynh C, Yuan X, Miguel DC, Renberg RL, Protchenko O, Philpott CC, Hamza I, Andrews NW.

PLoS Pathog. 2012;8(7):e1002795. doi: 10.1371/journal.ppat.1002795. Epub 2012 Jul 12.


Topologically conserved residues direct heme transport in HRG-1-related proteins.

Yuan X, Protchenko O, Philpott CC, Hamza I.

J Biol Chem. 2012 Feb 10;287(7):4914-24. doi: 10.1074/jbc.M111.326785. Epub 2011 Dec 15.


Identification of the genes affecting the regulation of riboflavin synthesis in the flavinogenic yeast Pichia guilliermondii using insertion mutagenesis.

Boretsky YR, Pynyaha YV, Boretsky VY, Fedorovych DV, Fayura LR, Protchenko O, Philpott CC, Sibirny AA.

FEMS Yeast Res. 2011 May;11(3):307-14. doi: 10.1111/j.1567-1364.2011.00720.x. Epub 2011 Mar 1.


Phosphatidylserine is involved in the ferrichrome-induced plasma membrane trafficking of Arn1 in Saccharomyces cerevisiae.

Guo Y, Au WC, Shakoury-Elizeh M, Protchenko O, Basrai M, Prinz WA, Philpott CC.

J Biol Chem. 2010 Dec 10;285(50):39564-73. doi: 10.1074/jbc.M110.177055. Epub 2010 Oct 5.


Metabolic response to iron deficiency in Saccharomyces cerevisiae.

Shakoury-Elizeh M, Protchenko O, Berger A, Cox J, Gable K, Dunn TM, Prinz WA, Bard M, Philpott CC.

J Biol Chem. 2010 May 7;285(19):14823-33. doi: 10.1074/jbc.M109.091710. Epub 2010 Mar 15.


Deficiency in frataxin homologue YFH1 in the yeast Pichia guilliermondii leads to missregulation of iron acquisition and riboflavin biosynthesis and affects sulfate assimilation.

Pynyaha YV, Boretsky YR, Fedorovych DV, Fayura LR, Levkiv AI, Ubiyvovk VM, Protchenko OV, Philpott CC, Sibirny AA.

Biometals. 2009 Dec;22(6):1051-61. doi: 10.1007/s10534-009-9256-x.


Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae.

Protchenko O, Shakoury-Elizeh M, Keane P, Storey J, Androphy R, Philpott CC.

Eukaryot Cell. 2008 May;7(5):859-71. doi: 10.1128/EC.00414-07. Epub 2008 Mar 7.


Response to iron deprivation in Saccharomyces cerevisiae.

Philpott CC, Protchenko O.

Eukaryot Cell. 2008 Jan;7(1):20-7. Epub 2007 Nov 9. Review. No abstract available.


Mutations and environmental factors affecting regulation of riboflavin synthesis and iron assimilation also cause oxidative stress in the yeast Pichia guilliermondii.

Boretsky YR, Protchenko OV, Prokopiv TM, Mukalov IO, Fedorovych DV, Sibirny AA.

J Basic Microbiol. 2007 Oct;47(5):371-7.


Development of a transformation system for gene knock-out in the flavinogenic yeast Pichia guilliermondii.

Boretsky YR, Pynyaha YV, Boretsky VY, Kutsyaba VI, Protchenko OV, Philpott CC, Sibirny AA.

J Microbiol Methods. 2007 Jul;70(1):13-9. Epub 2007 Mar 21.


A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.

Protchenko O, Rodriguez-Suarez R, Androphy R, Bussey H, Philpott CC.

J Biol Chem. 2006 Jul 28;281(30):21445-57. Epub 2006 May 22.


Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae.

Protchenko O, Philpott CC.

J Biol Chem. 2003 Sep 19;278(38):36582-7. Epub 2003 Jul 2.


The response to iron deprivation in Saccharomyces cerevisiae: expression of siderophore-based systems of iron uptake.

Philpott CC, Protchenko O, Kim YW, Boretsky Y, Shakoury-Elizeh M.

Biochem Soc Trans. 2002 Aug;30(4):698-702. Review.


[The reversion of Pichia guilliermondii transformants to the wild-type phenotype].

Piniaga IuV, Prokopiv TM, Petrishin AV, Khalimonchuk OV, Protchenko OV, Fedorovich DV, Boretskiĭ IuR.

Mikrobiologiia. 2002 May-Jun;71(3):368-72. Russian.


Three cell wall mannoproteins facilitate the uptake of iron in Saccharomyces cerevisiae.

Protchenko O, Ferea T, Rashford J, Tiedeman J, Brown PO, Botstein D, Philpott CC.

J Biol Chem. 2001 Dec 28;276(52):49244-50. Epub 2001 Oct 22.

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