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Items: 1 to 50 of 100

1.

Muscle activity prevents the uncoupling of mitochondria from Ca2+ Release Units induced by ageing and disuse.

Pietrangelo L, Michelucci A, Ambrogini P, Sartini S, Guarnier FA, Fusella A, Zamparo I, Mammucari C, Protasi F, Boncompagni S.

Arch Biochem Biophys. 2019 Mar 15;663:22-33. doi: 10.1016/j.abb.2018.12.017. Epub 2018 Dec 20.

2.

Addendum: Exercise-dependent formation of new junctions that promote STIM1-Orai1 assembly in skeletal muscle.

Boncompagni S, Michelucci A, Pietrangelo L, Dirksen RT, Protasi F.

Sci Rep. 2018 Nov 27;8(1):17463. doi: 10.1038/s41598-018-33063-0. No abstract available.

3.

Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy.

Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M.

EMBO J. 2019 Jan 3;38(1). pii: e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov 12.

4.

PERK inhibition attenuates the abnormalities of the secretory pathway and the increased apoptotic rate induced by SIL1 knockdown in HeLa cells.

Capone V, Clemente E, Restelli E, Di Campli A, Sperduti S, Ornaghi F, Pietrangelo L, Protasi F, Chiesa R, Sallese M.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3164-3180. doi: 10.1016/j.bbadis.2018.07.003. Epub 2018 Jul 7.

PMID:
30293566
5.

A 3D diffusional-compartmental model of the calcium dynamics in cytosol, sarcoplasmic reticulum and mitochondria of murine skeletal muscle fibers.

Marcucci L, Canato M, Protasi F, Stienen GJM, Reggiani C.

PLoS One. 2018 Jul 26;13(7):e0201050. doi: 10.1371/journal.pone.0201050. eCollection 2018.

6.

Aerobic Training Prevents Heatstrokes in Calsequestrin-1 Knockout Mice by Reducing Oxidative Stress.

Guarnier FA, Michelucci A, Serano M, Pietrangelo L, Pecorai C, Boncompagni S, Protasi F.

Oxid Med Cell Longev. 2018 Apr 3;2018:4652480. doi: 10.1155/2018/4652480. eCollection 2018.

7.

Mechanical parameters of the molecular motor myosin II determined in permeabilised fibres from slow and fast skeletal muscles of the rabbit.

Percario V, Boncompagni S, Protasi F, Pertici I, Pinzauti F, Caremani M.

J Physiol. 2018 Apr 1;596(7):1243-1257. doi: 10.1113/JP275404. Epub 2018 Jan 17.

PMID:
29148051
8.

Exercise-dependent formation of new junctions that promote STIM1-Orai1 assembly in skeletal muscle.

Boncompagni S, Michelucci A, Pietrangelo L, Dirksen RT, Protasi F.

Sci Rep. 2017 Oct 27;7(1):14286. doi: 10.1038/s41598-017-14134-0.

9.

Estrogens Protect Calsequestrin-1 Knockout Mice from Lethal Hyperthermic Episodes by Reducing Oxidative Stress in Muscle.

Michelucci A, Boncompagni S, Canato M, Reggiani C, Protasi F.

Oxid Med Cell Longev. 2017;2017:6936897. doi: 10.1155/2017/6936897. Epub 2017 Sep 10.

10.

Antioxidant Treatment Reduces Formation of Structural Cores and Improves Muscle Function in RYR1Y522S/WT Mice.

Michelucci A, De Marco A, Guarnier FA, Protasi F, Boncompagni S.

Oxid Med Cell Longev. 2017;2017:6792694. doi: 10.1155/2017/6792694. Epub 2017 Sep 10.

11.

Muscle Expression of SOD1G93A Triggers the Dismantlement of Neuromuscular Junction via PKC-Theta.

Dobrowolny G, Martini M, Scicchitano BM, Romanello V, Boncompagni S, Nicoletti C, Pietrangelo L, De Panfilis S, Catizone A, Bouchè M, Sandri M, Rudolf R, Protasi F, Musarò A.

Antioxid Redox Signal. 2018 Apr 20;28(12):1105-1119. doi: 10.1089/ars.2017.7054. Epub 2017 Oct 30.

PMID:
28931313
12.

Allele-Specific Silencing of Mutant mRNA Rescues Ultrastructural and Arrhythmic Phenotype in Mice Carriers of the R4496C Mutation in the Ryanodine Receptor Gene (RYR2).

Bongianino R, Denegri M, Mazzanti A, Lodola F, Vollero A, Boncompagni S, Fasciano S, Rizzo G, Mangione D, Barbaro S, Di Fonso A, Napolitano C, Auricchio A, Protasi F, Priori SG.

Circ Res. 2017 Aug 18;121(5):525-536. doi: 10.1161/CIRCRESAHA.117.310882. Epub 2017 Jun 15.

PMID:
28620067
13.

Strenuous exercise triggers a life-threatening response in mice susceptible to malignant hyperthermia.

Michelucci A, Paolini C, Boncompagni S, Canato M, Reggiani C, Protasi F.

FASEB J. 2017 Aug;31(8):3649-3662. doi: 10.1096/fj.201601292R. Epub 2017 May 2.

14.

Fatigue modulates dopamine availability and promotes flexible choice reversals during decision making.

Iodice P, Ferrante C, Brunetti L, Cabib S, Protasi F, Walton ME, Pezzulo G.

Sci Rep. 2017 Apr 3;7(1):535. doi: 10.1038/s41598-017-00561-6.

15.

Physical exercise in aging human skeletal muscle increases mitochondrial calcium uniporter expression levels and affects mitochondria dynamics.

Zampieri S, Mammucari C, Romanello V, Barberi L, Pietrangelo L, Fusella A, Mosole S, Gherardi G, Höfer C, Löfler S, Sarabon N, Cvecka J, Krenn M, Carraro U, Kern H, Protasi F, Musarò A, Sandri M, Rizzuto R.

Physiol Rep. 2016 Dec;4(24). pii: e13005. doi: 10.14814/phy2.13005. Erratum in: Physiol Rep. 2017 Mar;5(6):.

16.

Exercise-induced alterations and loss of sarcomeric M-line organization in the diaphragm muscle of obscurin knockout mice.

Randazzo D, Blaauw B, Paolini C, Pierantozzi E, Spinozzi S, Lange S, Chen J, Protasi F, Reggiani C, Sorrentino V.

Am J Physiol Cell Physiol. 2017 Jan 1;312(1):C16-C28. doi: 10.1152/ajpcell.00098.2016. Epub 2016 Oct 26.

17.

Role of the JP45-calsequestrin complex on calcium entry in slow twitch skeletal muscles.

Mosca B, Eckhardt J, Bergamelli L, Treves S, Bongianino R, De Negri M, Priori SG, Protasi F, Zorzato F.

J Biol Chem. 2016 Sep 23;291(39):20824. doi: 10.1074/jbc.A115.709071. No abstract available.

18.

Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles.

Mosca B, Eckhardt J, Bergamelli L, Treves S, Bongianino R, De Negri M, Priori SG, Protasi F, Zorzato F.

J Biol Chem. 2016 Jul 8;291(28):14555-65. doi: 10.1074/jbc.M115.709071. Epub 2016 May 4. Erratum in: J Biol Chem. 2016 Sep 23;291(39):20824.

19.

Mitochondria Association to Calcium Release Units is Controlled by Age and Muscle Activity.

Protasi F.

Eur J Transl Myol. 2015 Oct 27;25(4):257-62. doi: 10.4081/ejtm.2015.5604. eCollection 2015 Aug 24.

20.

Persistent Muscle Fiber Regeneration in Long Term Denervation. Past, Present, Future.

Carraro U, Boncompagni S, Gobbo V, Rossini K, Zampieri S, Mosole S, Ravara B, Nori A, Stramare R, Ambrosio F, Piccione F, Masiero S, Vindigni V, Gargiulo P, Protasi F, Kern H, Pond A, Marcante A.

Eur J Transl Myol. 2015 Mar 11;25(2):4832. doi: 10.4081/ejtm.2015.4832. eCollection 2015 Mar 11. Review.

21.

Age-dependent uncoupling of mitochondria from Ca2⁺ release units in skeletal muscle.

Pietrangelo L, D'Incecco A, Ainbinder A, Michelucci A, Kern H, Dirksen RT, Boncompagni S, Protasi F.

Oncotarget. 2015 Nov 3;6(34):35358-71. doi: 10.18632/oncotarget.6139.

22.

A CASQ1 founder mutation in three Italian families with protein aggregate myopathy and hyperCKaemia.

Di Blasi C, Sansanelli S, Ruggieri A, Moriggi M, Vasso M, D'Adamo AP, Blasevich F, Zanotti S, Paolini C, Protasi F, Tezzon F, Gelfi C, Morandi L, Pessia M, Mora M.

J Med Genet. 2015 Sep;52(9):617-26. doi: 10.1136/jmedgenet-2014-102882. Epub 2015 Jul 1.

PMID:
26136523
23.

Antioxidants protect calsequestrin-1 knockout mice from halothane- and heat-induced sudden death.

Michelucci A, Paolini C, Canato M, Wei-Lapierre L, Pietrangelo L, De Marco A, Reggiani C, Dirksen RT, Protasi F.

Anesthesiology. 2015 Sep;123(3):603-17. doi: 10.1097/ALN.0000000000000748.

24.

Oxidative stress, mitochondrial damage, and cores in muscle from calsequestrin-1 knockout mice.

Paolini C, Quarta M, Wei-LaPierre L, Michelucci A, Nori A, Reggiani C, Dirksen RT, Protasi F.

Skelet Muscle. 2015 Apr 18;5:10. doi: 10.1186/s13395-015-0035-9. eCollection 2015.

25.

Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres.

Boncompagni S, Arthurton L, Akujuru E, Pearson T, Steverding D, Protasi F, Mutungi G.

J Physiol. 2015 Jun 15;593(12):2679-92. doi: 10.1113/JP270502. Epub 2015 May 14.

26.

The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo.

Mammucari C, Gherardi G, Zamparo I, Raffaello A, Boncompagni S, Chemello F, Cagnin S, Braga A, Zanin S, Pallafacchina G, Zentilin L, Sandri M, De Stefani D, Protasi F, Lanfranchi G, Rizzuto R.

Cell Rep. 2015 Mar 3;10(8):1269-79. doi: 10.1016/j.celrep.2015.01.056. Epub 2015 Feb 26.

27.

New method for determining total calcium content in tissue applied to skeletal muscle with and without calsequestrin.

Lamboley CR, Kake Guena SA, Touré F, Hébert C, Yaddaden L, Nadeau S, Bouchard P, Wei-LaPierre L, Lainé J, Rousseau EC, Frenette J, Protasi F, Dirksen RT, Pape PC.

J Gen Physiol. 2015 Feb;145(2):127-53. doi: 10.1085/jgp.201411250.

28.

Role of Mitofusin-2 in mitochondrial localization and calcium uptake in skeletal muscle.

Ainbinder A, Boncompagni S, Protasi F, Dirksen RT.

Cell Calcium. 2015 Jan;57(1):14-24. doi: 10.1016/j.ceca.2014.11.002. Epub 2014 Nov 15.

29.

Deletion of small ankyrin 1 (sAnk1) isoforms results in structural and functional alterations in aging skeletal muscle fibers.

Giacomello E, Quarta M, Paolini C, Squecco R, Fusco P, Toniolo L, Blaauw B, Formoso L, Rossi D, Birkenmeier C, Peters LL, Francini F, Protasi F, Reggiani C, Sorrentino V.

Am J Physiol Cell Physiol. 2015 Jan 15;308(2):C123-38. doi: 10.1152/ajpcell.00090.2014. Epub 2014 Oct 29.

30.

AML cells carrying NPM1 mutation are resistant to nucleophosmin displacement from nucleoli caused by the G-quadruplex ligand TmPyP4.

De Cola A, Pietrangelo L, Forlì F, Barcaroli D, Budani MC, Graziano V, Protasi F, Di Ilio C, De Laurenzi V, Federici L.

Cell Death Dis. 2014 Sep 25;5:e1427. doi: 10.1038/cddis.2014.402. No abstract available.

31.

A mutation in the CASQ1 gene causes a vacuolar myopathy with accumulation of sarcoplasmic reticulum protein aggregates.

Rossi D, Vezzani B, Galli L, Paolini C, Toniolo L, Pierantozzi E, Spinozzi S, Barone V, Pegoraro E, Bello L, Cenacchi G, Vattemi G, Tomelleri G, Ricci G, Siciliano G, Protasi F, Reggiani C, Sorrentino V.

Hum Mutat. 2014 Oct;35(10):1163-70. doi: 10.1002/humu.22631. Epub 2014 Sep 10.

32.

Electrical stimulation counteracts muscle decline in seniors.

Kern H, Barberi L, Löfler S, Sbardella S, Burggraf S, Fruhmann H, Carraro U, Mosole S, Sarabon N, Vogelauer M, Mayr W, Krenn M, Cvecka J, Romanello V, Pietrangelo L, Protasi F, Sandri M, Zampieri S, Musaro A.

Front Aging Neurosci. 2014 Jul 24;6:189. doi: 10.3389/fnagi.2014.00189. eCollection 2014.

33.

Single delivery of an adeno-associated viral construct to transfer the CASQ2 gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age.

Denegri M, Bongianino R, Lodola F, Boncompagni S, De Giusti VC, Avelino-Cruz JE, Liu N, Persampieri S, Curcio A, Esposito F, Pietrangelo L, Marty I, Villani L, Moyaho A, Baiardi P, Auricchio A, Protasi F, Napolitano C, Priori SG.

Circulation. 2014 Jun 24;129(25):2673-81. doi: 10.1161/CIRCULATIONAHA.113.006901. Epub 2014 Jun 2.

PMID:
24888331
34.

Long-term high-level exercise promotes muscle reinnervation with age.

Mosole S, Carraro U, Kern H, Loefler S, Fruhmann H, Vogelauer M, Burggraf S, Mayr W, Krenn M, Paternostro-Sluga T, Hamar D, Cvecka J, Sedliak M, Tirpakova V, Sarabon N, Musarò A, Sandri M, Protasi F, Nori A, Pond A, Zampieri S.

J Neuropathol Exp Neurol. 2014 Apr;73(4):284-94. doi: 10.1097/NEN.0000000000000032.

PMID:
24607961
35.

Lifelong physical exercise delays age-associated skeletal muscle decline.

Zampieri S, Pietrangelo L, Loefler S, Fruhmann H, Vogelauer M, Burggraf S, Pond A, Grim-Stieger M, Cvecka J, Sedliak M, Tirpáková V, Mayr W, Sarabon N, Rossini K, Barberi L, De Rossi M, Romanello V, Boncompagni S, Musarò A, Sandri M, Protasi F, Carraro U, Kern H.

J Gerontol A Biol Sci Med Sci. 2015 Feb;70(2):163-73. doi: 10.1093/gerona/glu006. Epub 2014 Feb 18.

PMID:
24550352
36.

Post-natal heart adaptation in a knock-in mouse model of calsequestrin 2-linked recessive catecholaminergic polymorphic ventricular tachycardia.

Valle G, Boncompagni S, Sacchetto R, Protasi F, Volpe P.

Exp Cell Res. 2014 Feb 15;321(2):178-89. doi: 10.1016/j.yexcr.2013.12.014. Epub 2013 Dec 24.

PMID:
24370574
37.

Distinct regions of triadin are required for targeting and retention at the junctional domain of the sarcoplasmic reticulum.

Rossi D, Bencini C, Maritati M, Benini F, Lorenzini S, Pierantozzi E, Scarcella AM, Paolini C, Protasi F, Sorrentino V.

Biochem J. 2014 Mar 1;458(2):407-17. doi: 10.1042/BJ20130719.

PMID:
24325401
38.

Orai1-dependent calcium entry promotes skeletal muscle growth and limits fatigue.

Wei-Lapierre L, Carrell EM, Boncompagni S, Protasi F, Dirksen RT.

Nat Commun. 2013;4:2805. doi: 10.1038/ncomms3805.

39.

Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death.

Yarotskyy V, Protasi F, Dirksen RT.

PLoS One. 2013 Oct 15;8(10):e77633. doi: 10.1371/journal.pone.0077633. eCollection 2013.

40.

Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.

Scorzeto M, Giacomello M, Toniolo L, Canato M, Blaauw B, Paolini C, Protasi F, Reggiani C, Stienen GJ.

PLoS One. 2013 Oct 3;8(10):e74919. doi: 10.1371/journal.pone.0074919. eCollection 2013.

41.

Abnormal propagation of calcium waves and ultrastructural remodeling in recessive catecholaminergic polymorphic ventricular tachycardia.

Liu N, Denegri M, Dun W, Boncompagni S, Lodola F, Protasi F, Napolitano C, Boyden PA, Priori SG.

Circ Res. 2013 Jul 5;113(2):142-52. doi: 10.1161/CIRCRESAHA.113.301783. Epub 2013 May 14.

PMID:
23674379
42.

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease.

Nemazanyy I, Blaauw B, Paolini C, Caillaud C, Protasi F, Mueller A, Proikas-Cezanne T, Russell RC, Guan KL, Nishino I, Sandri M, Pende M, Panasyuk G.

EMBO Mol Med. 2013 Jun;5(6):870-90. doi: 10.1002/emmm.201202057. Epub 2013 Apr 30.

43.

Enhanced dihydropyridine receptor calcium channel activity restores muscle strength in JP45/CASQ1 double knockout mice.

Mosca B, Delbono O, Laura Messi M, Bergamelli L, Wang ZM, Vukcevic M, Lopez R, Treves S, Nishi M, Takeshima H, Paolini C, Martini M, Rispoli G, Protasi F, Zorzato F.

Nat Commun. 2013;4:1541. doi: 10.1038/ncomms2496.

44.

Mitochondrial dysfunction in skeletal muscle of amyloid precursor protein-overexpressing mice.

Boncompagni S, Moussa CE, Levy E, Pezone MJ, Lopez JR, Protasi F, Shtifman A.

J Biol Chem. 2012 Jun 8;287(24):20534-44. doi: 10.1074/jbc.M112.359588. Epub 2012 Apr 19.

45.

Viral gene transfer rescues arrhythmogenic phenotype and ultrastructural abnormalities in adult calsequestrin-null mice with inherited arrhythmias.

Denegri M, Avelino-Cruz JE, Boncompagni S, De Simone SA, Auricchio A, Villani L, Volpe P, Protasi F, Napolitano C, Priori SG.

Circ Res. 2012 Mar 2;110(5):663-8. doi: 10.1161/CIRCRESAHA.111.263939. Epub 2012 Jan 31.

PMID:
22298808
46.

Atrophy/hypertrophy cell signaling in muscles of young athletes trained with vibrational-proprioceptive stimulation.

Kern H, Pelosi L, Coletto L, Musarò A, Sandri M, Vogelauer M, Trimmel L, Cvecka J, Hamar D, Kovarik J, Löfler S, Sarabon N, Protasi F, Adami N, Biral D, Zampieri S, Carraro U.

Neurol Res. 2011 Dec;33(10):998-1009. doi: 10.1179/016164110X12767786356633.

PMID:
22196751
47.

Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage.

Yuen B, Boncompagni S, Feng W, Yang T, Lopez JR, Matthaei KI, Goth SR, Protasi F, Franzini-Armstrong C, Allen PD, Pessah IN.

FASEB J. 2012 Mar;26(3):1311-22. doi: 10.1096/fj.11-197582. Epub 2011 Nov 30.

48.

Lessons from calsequestrin-1 ablation in vivo: much more than a Ca(2+) buffer after all.

Protasi F, Paolini C, Canato M, Reggiani C, Quarta M.

J Muscle Res Cell Motil. 2011 Dec;32(4-5):257-70. doi: 10.1007/s10974-011-9277-2. Epub 2011 Dec 1.

PMID:
22130610
49.

Calsequestrin (CASQ1) rescues function and structure of calcium release units in skeletal muscles of CASQ1-null mice.

Tomasi M, Canato M, Paolini C, Dainese M, Reggiani C, Volpe P, Protasi F, Nori A.

Am J Physiol Cell Physiol. 2012 Feb 1;302(3):C575-86. doi: 10.1152/ajpcell.00119.2011. Epub 2011 Nov 2.

50.

Potential antibacterial activity of carvacrol-loaded poly(DL-lactide-co-glycolide) (PLGA) nanoparticles against microbial biofilm.

Iannitelli A, Grande R, Di Stefano A, Di Giulio M, Sozio P, Bessa LJ, Laserra S, Paolini C, Protasi F, Cellini L.

Int J Mol Sci. 2011;12(8):5039-51. doi: 10.3390/ijms12085039. Epub 2011 Aug 8.

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